Clinical trials: Senior, open to volunteers
Older Adults
The Effect of IoT-based Smart Exercises System in the Senior Adults: Coordination
Subjects are divided into two groups, (1) Control (Ctrl) and (2) Smart Exercise (SE) group. Participants in the Ctrl group are instructed to perform combined muscle strength and coordination exercises twice weekly, with each…
- Trial name
- NCT07772726
- Testing
- Smart Exercise program, Exercises
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Social Isolation in Older Adults, Quality of Life (QOL)
Virtual Senior Center
In a 3-group trial with randomization and follow-up for 12 months, we will compare use of the VSC as well as health and quality of life outcomes among 650 older adults in St.
- Conditions
- Social Isolation in Older Adults, Quality of Life (QOL), Activities of Daily Living
- Trial name
- VSC (NCT06946186)
- Testing
- Virtual Senior Center - GrandPad, Virtual Senior Center - No GrandPad
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Nursing Homes Residents, Deterioration, Clinical
Clinical Assessment and Treatment in the Nursing Home as an Alternative to Hospital Admission
This multicenter, cluster-randomized, unblinded quality-improvement study evaluates whether home-based clinical assessment by municipal acute care teams can safely reduce hospital admissions among nursing home residents…
- Conditions
- Nursing Homes Residents, Deterioration, Clinical, Infection, Dehydration
- Trial name
- NCT07756554
- Testing
- Home-based Clinical Assessment and Treatment
- Where
- 4 sites in Denmark
- Volunteers
- 9,000 people
- Sponsor
- Copenhagen University Hospital at Herlev
Disasters, Disaster Preparedness
Effectiveness of an Audiovisual Disaster-Education Intervention on Disaster Risk Perception and Preparedness Belief Among Senior High-School Adolescents
This cluster-randomized controlled trial tests whether a short, standardized disaster-education video improves two psychological precursors of disaster preparedness among senior high-school students in a hazard-prone district of…
- Conditions
- Disasters, Disaster Preparedness, Health Behavior, Risk Perception
- Trial name
- DERAP (NCT07781527)
- Testing
- Audiovisual disaster-education module, Attention-matched general-health video
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Tanjungpura University
Age-Related Macular Degeneration
A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration
Age-related macular degeneration (AMD) is an eye disease which causes people to lose their sharp central vision over time. Aging damages the macula, which is in the middle of the retina - the light-sensitive part at the back of…
- Trial name
- NCT03178149
- Testing
- ASP7317, tacrolimus, trimethoprim-sulfamethoxazole
- Where
- 20 sites in United States
- Volunteers
- 42 people
- Sponsor
- Astellas Institute for Regenerative Medicine
Frailty, Cardiac Surgery
SAGE-Heart : Senior Assessment fraGility and Post-opErative QALYs 1 Year After Emergency HEART Surgery for Patients Aged 75 and Older
The hypothesis is that the preoperative Clinical Frailty Score (CFS) is a predictive factor for a loss in quality-adjusted life years (QALYs) one year after emergency cardiac surgery under cardiopulmonary bypass (CPB) in patients…
- Conditions
- Frailty, Cardiac Surgery, QALYs
- Trial name
- SAGE-Heart (NCT07677319)
- Testing
- Phone Calls
- Where
- France
- Volunteers
- 265 people
- Sponsor
- University Hospital, Bordeaux
Graft Failure, Death
European Transplant Registry of Senior Renal Transplant Recipients on Advagraf
SENIOR transplant Registry European transplant registry of senior renal transplant recipients (above the age of 65 years) receiving initial immunosuppression with tacrolimus once daily, mycophenolate and steroids to investigate…
- Conditions
- Graft Failure, Death, Acute Rejection of Renal Transplant, Infections
- Trial name
- SENIOR (NCT02558452)
- Testing
- Tacrolimus once daily (Advagraf)
- Volunteers
- 1,000 people
- Sponsor
- Klemens Budde
Healthy Lifestyle
SENior PRIorat: Participatory Research for the Improvement of Lifestyles, Quality of Life, Emotional Well-being, and Locomotor Abilities of Older Adults in the Priorat
Spain is experiencing a demographic shift towards an ageing population. In 2022, 20.1% of Spaniards were 65 or older, a figure projected to reach 30.4% by 2050.
- Trial name
- SENPRI (NCT07189533)
- Testing
- Co-created intervention
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Achilles Tendinopathy (AT)
Change in ATOR Screening Test Scores Over 12 Weeks
Achilles tendinopathy (AT) is one of the most common overuse injuries in runners, with an estimated incidence ranging from 0.6% to 18.5% of all running-related injuries, reaching up to 52% in elite runners.
- Trial name
- ATOR (NCT07497217)
- Testing
- Alfredson Exercise Program + Health Education + Analytical Stretching, Alfredson Exercise Program + Health Education
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Zaragoza
Patient Safety
Simulation Practices and Medical Error Tendencies in Nursing Students
As the professional group that has the most frequent contact with patients, nurses are critical to the sustainability of safe care.
- Trial name
- NCT07349355
- Testing
- Standardized patient, İn-situ simulation
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Selçuk Görücü
Postpartum Hemorrhage, Simulation Based Medical Education
Effect of Simulation-Based Postpartum Hemorrhage Training on Team Performance in Senior Anesthesiology Teams
This prospective interventional study aims to evaluate the effect of simulation-based postpartum hemorrhage (PPH) training on team performance and crisis resource management skills among senior anesthesiology residents.
- Trial name
- PPH-SIM (NCT07519252)
- Testing
- Simulation-Based Postpartum Hemorrhage Training
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Mehmet Kırıköz
Myopia
Screening for Hyperopic Reserve in Kindergarten
Screening for hyperopic reserve among senior kindergarten children is an important population-based eye health measure. Hyperopic reserve refers to physiological hyperopia in young children, which acts as a natural buffer against…
- Trial name
- NCT07851532
- Where
- China
- Volunteers
- 134,000 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Healthy Adult Participants, Gut Microbiomes
DORA - A Study Using Digital Health Tools/Platform to Explore the Impact of the Consumption of Senior Milk Powder Containing Synbiotics on the Gut micRobiome in Healthy Aging Individuals
The DORA study is a single-arm, open-label, interventional exploratory study designed to evaluate the impact of a synbiotic-containing senior milk powder on the gut microbiome and selected biological, physiological, and digital…
- Conditions
- Healthy Adult Participants, Gut Microbiomes, AI
- Trial name
- DORA (NCT07575529)
- Testing
- Synbiotic Nutritional Product
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Danone Asia Pacific Holdings Pte, Ltd.
Dietary Quality
Teaching Kitchens Intervention for Older Adults in a Senior Center in New England
This study will evaluate a culinary nutrition intervention designed to improve the quality of meals served to older adults participating in a senior center.
- Trial name
- NCT07609368
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tufts University
Refractive Errors
Consistency of an Automated Subjective Refraction Program Between Personnel With Diverse Professional Backgrounds and Senior Optometrists
This study aims to evaluate the performance of automated subjective refraction performed by operators with different professional backgrounds.
- Trial name
- NCT07891884
- Testing
- Nurse-Operated Automated Subjective Refraction, Village Doctor-Operated Automated Subjective Refraction, Lay Personnel-Operated Automated Subjective Refraction
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Healthy Aging
An Aging Healthy Intervention for Older Adults Delivered by Community Health Workers in Senior Centers: A Clinical Trial
The aCT Study will develop, implement and evaluate a community health worker (CHW) integrated model of care delivery for older adults that is senior center based.
- Trial name
- aCT (NCT07428174)
- Testing
- aCT CHW intervention
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- George Mason University
Depression
Lay-Delivered Behavioral Activation in Senior Centers
In response to large numbers of senior center clients who suffer untreated depression and the dearth of geriatric mental health providers, the investigators have simplified Behavioral Activation to be delivered by lay volunteers…
- Trial name
- NCT04621877
- Testing
- Volunteer-delivered Behavioral Activation, Master's level clinician-delivered Behavioral Activation
- Where
- 25 sites in United States
- Volunteers
- 288 people
- Sponsor
- University of Washington
Fall, Pressure Ulcer
PROSENIOR. Prevention of Pressure Ulcers, Malnutrition, Poor Oral Health and Falls Among Older Persons Receiving Municipal Health Care and Are Registered in the Quality Registry Senior Alert
Inclusion criteria for study I and II is nurse aides, registered nurses and managers working in nursing homes who register in Senior Alert.
- Conditions
- Fall, Pressure Ulcer, Malnutrition, Oral Health
- Trial name
- NCT05308862
- Testing
- Care process for assessements of risks
- Where
- Sweden
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Malmö University
Ovarian Cancer, Surgery
PROADAPT-ovary/EWOC-2
PROADAPT is a standardized geriatric intervention that is currently being co-constructed during an exploratory phase on a multi-professional and multi-disciplinary basis after a systematic analysis of published data (Figure).
- Trial name
- NCT04284969
- Testing
- PROADAPT program
- Where
- 11 sites in France
- Volunteers
- 292 people
- Sponsor
- Hospices Civils de Lyon
Fall Prevention
Evaluation of a Foot Health Program Incorporating Minimalist Footwear on Fall Risk Factors in Older People Living in Senior Nursing Homes: a Pilot Study.
Every year in France, 2 million falls by people over 65 are responsible for 10,000 deaths, the leading cause of accidental death, and more than 130,000 hospitalizations.
- Trial name
- GRAND'PAS (NCT06996444)
- Testing
- Program Including Various Workshops aiming to preserve elderly's autonomy through foot health
- Where
- 5 sites in France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Emile Roux