Clinical trials: Senior
Older Adults
The Effect of IoT-based Smart Exercises System in the Senior Adults: Coordination
Subjects are divided into two groups, (1) Control (Ctrl) and (2) Smart Exercise (SE) group. Participants in the Ctrl group are instructed to perform combined muscle strength and coordination exercises twice weekly, with each…
- Trial name
- NCT07772726
- Testing
- Smart Exercise program, Exercises
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Kidney Transplantation
Minimizing Immunosuppression in Old for Old Kidney Transplantation
Kidney transplantation in the elderly is a challenge since patient's co-morbidity and the decreased injury threshold of older grafts may limit the benefits of transplantation in these patients.
- Trial name
- ESP-CNI (NCT00912678)
- Testing
- MMF (Cellcept) and Steroids, Tacrolimus (Prograf)
- Where
- 5 sites in Germany
- Volunteers
- 90 people
- Sponsor
- University of Luebeck
Exercise Training
Golf for Healthy Aging
Aging is associated with physiological declines that could impair the ability to perform activities of daily living and thus impair the quality of life of older adults.
- Trial name
- GHA (NCT03916887)
- Testing
- Golf instruction
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Hypertension
DASH Diet Intervention at Senior Centers
The Carter Burden Network (CBN) is an New York City senior services agency, providing vital meal programs for low-income, minority seniors, age 60 and over.
- Trial name
- NCT03993808
- Testing
- Revision of congregate meal menus and recipes to align with parameters of DASH eating plan, On-site blood pressure monitoring, Home self blood pressure monitoring
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Mortality, Pediatric
Operative Duration as a Predictor of Mortality in Pediatric Emergency Surgery
Introduction Operative duration is an important but under-studied predictor of mortality in emergency laparotomies. Aims \& Objectives The objective of this study was to quantify the effect of duration of emergency laparotomy in…
- Conditions
- Mortality, Pediatric, Laparotomy, Emergencies
- Trial name
- NCT03270930
- Testing
- Emergency laparotomy
- Volunteers
- 213 people
- Sponsor
- Jawaharlal Nehru Medical College
The Effect of Milk Components on the Response to Pneumococcal Vaccines in the Elderly
The Effect of Milk Components on the Response to the Pneumonia Vaccine in Senior Citizens
The purpose of this study is to determine if the daily use of a certain amount and type of milk component for 2 months provides a significant stimulation to the immune system and specifically increases the chances of being…
- Trial name
- NCT01626300
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Unspecified Adult Solid Tumor, Protocol Specific
Screening Tools to Predict Treatment Outcome in Older Cancer Patients Who Are Undergoing Treatment
RATIONALE: Questionnaires that measure how well older patients think, learn, remember, and make judgments and carry out daily activities may improve the ability to plan treatment for patients with cancer.
- Trial name
- NCT01005693
- Testing
- questionnaire administration, cognitive assessment, examination
- Where
- 4 sites in Belgium
- Volunteers
- 300 people
- Sponsor
- Ziekenhuis Netwerk Antwerpen (ZNA)
Pre-frail Senior Adults
What Are the Effects of a Bilateral Hip Exoskeleton During Daily Use by 65+ Adults?
Despite the huge popularity exoskeletons have gained in the past years and the benefits that they have shown to provide to users, there are still many aspects of wearing an exoskeleton that have yet to be determined.
- Trial name
- NCT06041100
- Testing
- Exoskeleton
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Social Isolation in Older Adults, Quality of Life (QOL)
Virtual Senior Center
In a 3-group trial with randomization and follow-up for 12 months, we will compare use of the VSC as well as health and quality of life outcomes among 650 older adults in St.
- Conditions
- Social Isolation in Older Adults, Quality of Life (QOL), Activities of Daily Living
- Trial name
- VSC (NCT06946186)
- Testing
- Virtual Senior Center - GrandPad, Virtual Senior Center - No GrandPad
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Colon Cancer Patients Receiving Chemotherapy in the Adjuvant or Metastatic Setting, Aged 70 or Older
MOST: Mediterranean Oncology Senior Tests
MOST is a longitudinal study whose aim is to test the hypothesis that frailty markers are better at detecting vulnerable patients and that they are a better "Adverse Events" predictive tool than the CGA (Comprehensive Geriatric…
- Trial name
- MOST (NCT02148731)
- Testing
- Frailty markers
- Where
- 8 sites in France
- Volunteers
- 180 people
- Sponsor
- Association Sud pour la Recherche en Oncogériatrie
Nursing Homes Residents, Deterioration, Clinical
Clinical Assessment and Treatment in the Nursing Home as an Alternative to Hospital Admission
This multicenter, cluster-randomized, unblinded quality-improvement study evaluates whether home-based clinical assessment by municipal acute care teams can safely reduce hospital admissions among nursing home residents…
- Conditions
- Nursing Homes Residents, Deterioration, Clinical, Infection, Dehydration
- Trial name
- NCT07756554
- Testing
- Home-based Clinical Assessment and Treatment
- Where
- 4 sites in Denmark
- Volunteers
- 9,000 people
- Sponsor
- Copenhagen University Hospital at Herlev
Family, Alzheimer Dementia
The Senior Companion Program Plus
Alzheimer's disease and related dementia (ADRD) is one of the most challenging chronic health conditions in the United States and considerable disparities exist in the diagnosis and prevalence of ADRD among communities of color.
- Trial name
- SCP Plus (NCT03602391)
- Testing
- SCP Plus
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Disasters, Disaster Preparedness
Effectiveness of an Audiovisual Disaster-Education Intervention on Disaster Risk Perception and Preparedness Belief Among Senior High-School Adolescents
This cluster-randomized controlled trial tests whether a short, standardized disaster-education video improves two psychological precursors of disaster preparedness among senior high-school students in a hazard-prone district of…
- Conditions
- Disasters, Disaster Preparedness, Health Behavior, Risk Perception
- Trial name
- DERAP (NCT07781527)
- Testing
- Audiovisual disaster-education module, Attention-matched general-health video
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Tanjungpura University
Physical Inactivity
Comparison of the Effects of Green Exercise Programs Including Resistance and Aerobic Exercises
It was aimed to evaluate the effects of aerobic exercise and resistance exercises performed together with aerobic exercise, applied in the concept of green exercise with a multidisciplinary team (specialist doctors…
- Trial name
- GREENCITY (NCT05958745)
- Testing
- Aerobic Exercise, Aerobic + resistance exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Mild Cognitive Impairment
Applying a Person-Centered Approach to Enhance Cognitive Training in Senior Living Community Residents With Mild Cognitive Impairment
Computerized cognitive interventions (CCIs) have been increasingly widely implemented among older adults with mild cognitive impairment (MCI).
- Trial name
- CogT-PACT (NCT03292705)
- Testing
- PEP, CCI
- Where
- 2 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Older Adults (65 Years and Older), Cognitive Impairment, Mild
How Video Game Therapy Affects Thinking and Emotions in Older Adults With Cognitive Impairment
Golden Gamers Go is running a study together with Rey Juan Carlos University to better understand how videogames can help older adults, especially those with memory problems or cognitive decline.
- Trial name
- NCT07615647
- Testing
- Videogames masterclass, Therapy with videogames
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Golden Gamers Go SL
Hypertension
Aliskiren Study of Safety and Efficacy in Senior Hypertensives
This study is designed to compare the blood pressure lowering efficacy of aliskiren, a combination of aliskiren plus amlodipine, and ramipril in elderly patients with mild to moderate hypertension.
- Trial name
- ASSESS (NCT01922141)
- Testing
- Aliskiren, Amlodipine, Ramipril
- Sponsor
- Novartis Pharmaceuticals
Psychological Resilience, Career Decision Making
Effect of a Nurse-Led Transition Program on Resilience and Career Decisions in Senior Students
The transition to higher education is a critical stage that affects young people's academic, emotional, and professional development.
- Trial name
- NCT07823881
- Testing
- Nurse-Led On-Campus Experiential Transition Program
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Coronary Disease
Post-Market Registry to Evaluate the Safety and Efficacy of the The SUPRAFLEX CRUZ™ Sirolimus Eluting Coronary Stent System in the Treatment of an Octo- and Nonagenerian All-Comer Patient Cohort With Coronary Artery Disease - the Cruz Senior Study
Prospective, multi-centre, open-label, single-armed, non-interventional observational clinical investigation designed to enrol 2000 octo- and nonagenerian all-comer patients with coro-nary artery disease in up to 37 sites in…
- Trial name
- NCT04612179
- Testing
- The SUPRAFLEX CRUZ™ Sirolimus eluting coronary stent system
- Where
- Germany
- Volunteers
- 2,017 people
- Sponsor
- IHF GmbH - Institut für Herzinfarktforschung
Age-Related Macular Degeneration
A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration
Age-related macular degeneration (AMD) is an eye disease which causes people to lose their sharp central vision over time. Aging damages the macula, which is in the middle of the retina - the light-sensitive part at the back of…
- Trial name
- NCT03178149
- Testing
- ASP7317, tacrolimus, trimethoprim-sulfamethoxazole
- Where
- 20 sites in United States
- Volunteers
- 42 people
- Sponsor
- Astellas Institute for Regenerative Medicine