Clinical trials: Self-harm Behavior
Suicide Prevention
Evaluating Primary Suicide Prevention in Adolescents With Risk Factors
Suicide is one of the main causes of death among teenagers. Because it is preventable, primary prevention of suicide has become a public health priority, with encouraging results in promoting suicide awareness and reducing…
- Trial name
- ESPAIR (NCT06551038)
- Testing
- Primary suicide prevention intervention, Art-based control intervention
- Where
- 19 sites in Switzerland
- Volunteers
- 240 people
- Sponsor
- Stephanie Baggio
Suicide
Neurocognitive Mechanisms of Perimenstrual Estrogen Effects on Suicidality
This within-person, crossover, 2-condition, placebo-controlled study compares the impact of two perimenstrual conditions on severity of suicidal symptoms in females with past-month suicidality but minimal risk of imminent suicide…
- Trial name
- CLEAR-4 (NCT06191289)
- Testing
- Transdermal Estradiol
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Illinois at Chicago
Self-injurious Behavior, Self Mutilation
Evaluation of Naltrexone as a Treatment for Self-injurious Behavior
The proposed study examines the effect of oral naltrexone on self-injurious behavior (SIB) in adolescents and adults of normal intelligence.
- Trial name
- NTX-SIB (NCT02726035)
- Testing
- Naltrexone
- Where
- United States
- Sponsor
- Western Michigan University School of Medicine
Rumination, Depression
Adolescent Mindfulness Mobile App Study (RCT)
Rumination involves focusing on negative emotions repeatedly and is a risk factor for developing depression, anxiety, and self-injury. These negative outcomes increase in adolescence.
- Conditions
- Rumination, Depression, Anxiety, Self-Injurious Behavior
- Trial name
- AMMASRCT (NCT03900416)
- Testing
- Mindfulness App
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Lawrence University
Suicide, Suicide Attempt
Nudging Parental Actions for Youth Suicide Prevention
The goal of the study is to determine effectiveness of a behaviorally informed text messaging intervention to help parents increase safety practices and reduce their teens' access to lethal means following a suicide-related…
- Trial name
- NCT07383714
- Testing
- Text-messaging for safety reminders, Text-messaging with safety reminders and risk framing
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- University of Texas Southwestern Medical Center
Battered Women, Suicide, Attempted
Effectiveness of Empowerment Group Sessions for Treating Suicidal African American Women in Abusive Relationships
This study will evaluate the effectiveness of culturally competent psychoeducational empowerment sessions in treating suicidal African-American women who are in abusive relationships.
- Trial name
- NCT00601939
- Testing
- Psychoeducational intervention (PEI), Enhanced treatment as usual (ETAU)
- Where
- United States
- Volunteers
- 241 people
- Sponsor
- Emory University
Suicide, Schizophrenia
Alexithymia Intervention for Suicide
Suicide rates among Veterans with Serious Mental Illness (SMI) are intractably high, representing a serious public health concern and a critical target for interventions.
- Conditions
- Suicide, Schizophrenia, Bipolar Disorder, Post Traumatic Stress Disorder
- Trial name
- ALEXIS (NCT05724953)
- Testing
- Affective Awareness
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- VA Office of Research and Development
Suicidal Ideation, Suicide
The Impact of Ketamine on the Reward Circuitry of Suicidal Patients
Every 40 seconds, someone in the world dies by suicide. There is a lack of effective and safe antisuicidal agents for preventing suicide attempts.
- Trial name
- NCT02532153
- Testing
- Ketamine Hydrochloride
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Suicidal Ideation
Effectiveness of a CBT Online-based Program to Reduce Suicide Ideation Among School Adolescents
This is a single-blind two armed cluster randomized controlled trial (cRCT) aimed to determine the effectiveness of an integrated blended intervention (online a face-to face sessions) to reduce suicidal ideation (primary…
- Trial name
- NCT05229302
- Testing
- Reframet IT, Usual care
- Where
- Chile
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Talca
Self Harm
Adaptation of STEPPS Program for Addressing Emotional Dysregulation and Self-harming Behaviors in Penitentiary Centers
The overall objective of this study is to assess the feasibility, within the Penitentiary Centers of Catalonia, of adapting the STEPPS program for addressing and preventing emotional dysregulation and self-harming behaviors…
- Trial name
- NCT06297460
- Testing
- Systems Training for Emotional Predictability & Problem Solving (STEPPS)
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Universitat Jaume I
Self Harm
Multicenter Study to Evaluate the Clinical and Cost Effectiveness of a Youth Culturally Adapted Therapy (YCMAP)
To evaluate the clinical and cost-effectiveness of a youth culturally adapted manual assisted therapy (YCMAP) in Pakistani Adolescents with a history of self-harm
- Trial name
- NCT04131179
- Testing
- Youth Culturally Adapted Manual Assisted Psychological Therapy (Y-CMAP)
- Where
- 3 sites in Pakistan
- Volunteers
- 684 people
- Sponsor
- Pakistan Institute of Living and Learning
Leadership, Self-Harm
Implementing Evidence-Based Nursing: Leadership and Organizational Change for Implementation
This study aims to find out whether a leadership and organizational development program called the LOCI (Leadership and Organizational Change for Implementation) strategy can help nurses and their managers use the best available…
- Conditions
- Leadership, Self-Harm, Malnutrition Elderly
- Trial name
- LOCI-FIN-P (NCT07378696)
- Testing
- Leadership and organizational change for implementation
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- Jaakko Varpula
Assisted Suicide
Assisted Suicide in Switzerland
Background: Researchers want to learn more about how the Swiss model of assisted suicide works. To do this, they have interviewed 25 Swiss experts.
- Trial name
- NCT04261088
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Suicidal Ideation, Suicide, Attempted
Establishing Efficacy of an Inpatient Intervention and Phone App to Reduce Suicidal Risk
In this 2-site study, University of Texas Southwestern Medical Center (UTSW) and Western Psychiatric Institute and Clinic (WPIC), the investigators will conduct a randomized clinical trial (RCT) in 240 psychiatrically…
- Trial name
- ASAP+BRITE (NCT03825588)
- Testing
- ASAP (As Safe As Possible), BRITE smart phone app, TAU (treatment as usual)
- Where
- 2 sites in United States
- Volunteers
- 241 people
- Sponsor
- University of Texas Southwestern Medical Center
Suicide
Pilot Study of a Brief, Recovery-focused Intervention for Crisis Stabilization Centers
Crisis Stabilization Centers (CSCs) have a unique role to play in Emergency Department diversion and suicide-specific care. However, brief interventions tailored for CSC settings are needed.
- Trial name
- THRIVE (NCT05558891)
- Testing
- THRIVE, Usual Care
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Centerstone Research Institute
Mental Health Issue
The Relationship Between Internet-use Behavior and Mental Health in Youth
Introduction: WHO defines youth as 15-24 years age group. At this stage, the brain is still under development, with high impulsiveness, being fond of stimulation and yearning for peer life.
- Trial name
- NCT06284551
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Suicidal Ideation
Home-based tDCS for Prevention of Suicidal Ideation
Risk for suicide is elevated in the period after discharge from hospital among adults with major affective disorder. The primary objective of this study is to investigate the feasibility of delivering tDCS sessions for high-risk…
- Trial name
- NCT05280756
- Testing
- Home-based transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Rochester
Attempted Suicide, Depression
Culturally Adapted Cognitive Behavioral Therapy for Prevention of Self Harm
Aim: To adapt and develop a culturally appropriate psychological intervention and test its feasibility, and acceptability for the patients presenting to general hospital following self-harm in Karachi Pakistan.
- Trial name
- NCT01308151
- Testing
- Other
- Where
- 4 sites in Pakistan
- Volunteers
- 221 people
- Sponsor
- Pakistan Institute of Living and Learning
Suicide, Attempted, Suicide Threat
Written Exposure Therapy for Suicide Prevention
Military service members admitted to inpatient psychiatry for self-injurious thoughts and behaviors (SITBs) represent an at-risk group for continued SITBs and rehospitalizations in the post-discharge period.
- Trial name
- NCT05878795
- Testing
- WET-SP, TAU
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Boston University
Major Depressive Disorder, Suicidal Ideation
Paliperidone and Lithium in the Treatment of Suicidality - Treatment Indication and Epigenetic Regulation
The study aims to use a combined clinical and translational approach to identify an efficient pharmacotherapy for the acute management of suicidality and the epigenetic regulation associated with the treatment.The primary…
- Trial name
- AFSP (NCT01134731)
- Testing
- paliperidone, lithium
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Alabama at Birmingham