Clinical trials: Screening Colonoscopy
CRC
Evaluation of the Motus Gl CleanUp System During Screening Colonoscopy
Motus Gl is developing a single-use device that attaches to a standard colonoscope, thereby integrating colon cleansing, screening and treatment into one procedure. The device creates turbulence within the colon using water jets.
- Trial name
- NCT02161549
- Testing
- Motus Gl CleanUp System
- Where
- Spain
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Motus GI Medical Technologies Ltd
Colorectal Cancer, Advanced Adenocarcinoma
Retrospective Analysis of Colorectal Cancer Screening Results
The purpose of this study is to retrospectively analyze colorectal cancer screening data of 40-74 year old population in Shipai Town, Dongguan City.
- Conditions
- Colorectal Cancer, Advanced Adenocarcinoma, Hyperplastic Polyp, Colorectal Neoplasms
- Trial name
- NCT05374369
- Testing
- SDC2 Gene Methylation Test and Q-FIT Test, Colonoscopy and/or pathological examination
- Where
- China
- Volunteers
- 822 people
- Sponsor
- Creative Biosciences (Guangzhou) Co., Ltd.
Colon Cancer
Polyp Detection With the EndoRings™: A Randomized Tandem Colonoscopy Study
To compare the adenoma miss rate with the EndoRings™ vs. the adenoma miss rate with Standard view colonoscopy. To compare the polyp miss rate with the EndoRings™ vs.
- Trial name
- NCT01955122
- Testing
- Tandem Colonoscopy
- Where
- 3 sites in United States, Israel and 1 more
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- EndoAid
Colonic Polyp
A Clinical Study on Endoscopic and Histopathological Outcomes of Screening and Surveillance Colonoscopies
The objective of this study is to collect colonoscopy data for use in the development and testing of artificial intelligence (AI) devices for colonoscopies.
- Trial name
- CODACO (NCT05869838)
- Testing
- Colonoscopy
- Where
- 2 sites in Germany, Spain
- Volunteers
- 600 people
- Sponsor
- Olympus Europe SE & Co. KG
Colorectal Cancer, Colorectal Polyp
Feasibility and Safety of MiWEndo-assisted Colonoscopy
The study involves the planned use of a new microwave-based device during colonoscopy procedures in a small group of patients to assess the preliminary safety of its use and lack of normal clinical practice modification.
- Conditions
- Colorectal Cancer, Colorectal Polyp, Colorectal Adenoma, Colorectal Neoplasms
- Trial name
- MiWEndo1 (NCT05477836)
- Testing
- MiWEndo-assisted colonoscopy
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- MiWEndo Solutions S.L.
Natural Killer Cell Cytokine Production
Measurement of NK Cell Activity in Whole Blood in Subjects Being Screened for Colorectal Cancer Using Colonoscopy
This study will look at measuring the activity of natural killer (NK) cells using the in vitro diagnostic device NK Vue in subjects being screened for colorectal cancer using colonoscopy.
- Trial name
- NCT02291198
- Testing
- NK Vue: NK cell activity in stimulated whole blood
- Where
- Canada
- Volunteers
- 1,081 people, healthy volunteers welcome
- Sponsor
- ATGen Canada Inc
Colon Cancer
Study to Assess the Tolerability, Safety and Efficacy of an Adapted Gut Cleansing Solution in Routine Colon Cleansing Prior to Colonoscopies
It is particularly important that thorough gut cleansing is achieved prior to the colonoscopy for the procedure to be successful.
- Trial name
- NCT01251237
- Testing
- NRL0706
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Norgine
Colonoscopy, Colorectal Cancer Screening
Triton 1.5 Robotic System for Diagnostic Colonoscopy in the Middle East
The purpose of this study is to gain early experience in the Triton 1.5 System in performing diagnostic, screening, surveillance, and basic therapeutic tasks (e.g., polypectomy for lesions ≤ 2 cm).
- Trial name
- CARE-UAE (NCT07835542)
- Testing
- Diagnostic Test: Diagnostic Colonoscopy
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Neptune Medical
Colonoscopy
Comparison of 2L NRL994 With NaP Preparation in Colon Cleansing Prior to Colonoscopies for Colon Tumor Screening
To compare the efficacy, acceptability and safety of the new 2 liter gut cleansing solution (Moviprep) and NaP preparation in routine colon cleansing prior to tumor screening colonoscopies
- Trial name
- NCT00427089
- Testing
- Macrogol 3350 Na sulphate NaCl KCl Ascorbic Acid Na Ascorbate, Sodium Phosphate solution (NaP)
- Where
- 12 sites in Germany
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Norgine
Colonoscopy, Colorectal Cancer Screening
Triton 1.5 Robotic System for Diagnostic Colonoscopy
This study is a prospective, single-arm, non-randomized, single-site study, focused on evaluating the safety and efficacy of the Triton 1.5 System in diagnostic and basic therapeutic colonoscopy.
- Trial name
- CARE II (NCT07606963)
- Testing
- Diagnostic Test: Diagnostic Colonoscopy
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Neptune Medical
Colorectal Adenoma, Colorectal Polyp
To Compare Artificial Intelligence Software Aided Adenoma Detection in Screening Colonoscopies Versus Standard Colonoscopy Without Artificial Intelligence Software Assistance in Participants Between 45 and 75 Years of Age
The aim of this study is to assess the efficacy of Ultivision Artificial Intelligence (AI) Software in detecting adenomas in screening colonoscopy procedures. The safety of Ultivision AI Software will also be assessed.
- Conditions
- Colorectal Adenoma, Colorectal Polyp, Colorectal Adenocarcinoma, Colorectal SSA
- Trial name
- AIDA (NCT04196088)
- Testing
- Ultivision Artificial Intelligence Software, No Artificial Intelligence Software enhancement
- Where
- 9 sites in United States
- Volunteers
- 978 people, healthy volunteers welcome
- Sponsor
- Docbot, Inc.
Screening Colonoscopy, Surveillance Colonoscopy
A Study to Evaluate the Safety and Efficacy of the Use of ME-APDS During Colonoscopy
ME-APDS is a device (software-based with hardware) developed by Magentiq Eye LTD and intended to support the decision of the endoscopist on polyps which appear in the colonoscopy video during the colonoscopy procedure.
- Trial name
- NCT04640792
- Testing
- Screening or Surveillance Conventionall colonoscopy
- Where
- 11 sites in United States, Germany and 2 more
- Volunteers
- 952 people, healthy volunteers welcome
- Sponsor
- Magentiq Eye LTD
Colonoscopy, Colorectal Cancer Screening
Effect of Counseling and Education on Mechanical Bowel Preparation
The goal of this clinical trial is to learn whether enhanced education and counseling can improve bowel preparation before colonoscopy in high-risk patients.
- Trial name
- EEFEC-AMBP (NCT07093099)
- Testing
- Enhanced Education Package for Bowel Preparation, Standard Education Leaflet
- Where
- Palestinian Territories
- Volunteers
- 150 people
- Sponsor
- Al-Ram Drug Store
Colorectal Screening
Demonstrating Effective Salvage of Inadequate Colonoscopies
The aim of this study is to demonstrate that the use of the Pure-Vu EVS System can salvage inadequately prepared optical colonoscopies (OCs) to adequate OCs.
- Trial name
- NCT05585879
- Testing
- Pure-Vu EVS
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Motus GI Medical Technologies Ltd
Polypoid Lesions
Evaluation of Check-Cap C-Scan System in Providing Structural Information and Detection of Polypoid Lesions
The purpose of this study is to establish the efficacy of Check-Cap's C-Scan System in providing structural information on colonic polypoid lesions and masses, as an adjacent tool to FIT.
- Trial name
- NCT02990715
- Testing
- C-Scan System
- Where
- 3 sites in Israel
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Check-Cap Ltd.
Colorectal Cancer
The Safety and Efficacy of Methylene Blue MMX® Modified Release Tablets Administered to Subjects Undergoing Screening or Surveillance Colonoscopy
Evaluation of the histologically proven adenoma and carcinoma detection rate in patients undergoing a full colonoscopy with and without mucosal contrast enhancement, obtained with 200 mg of Methylene Blue MMX® tablets.
- Trial name
- NCT01694966
- Testing
- Methylene Blue MMX®
- Where
- 19 sites in United States, Belgium and 6 more
- Volunteers
- 1,249 people, healthy volunteers welcome
- Sponsor
- Cosmo Technologies Ltd
Colorectal Cancer, Polyp of Colon
EAGLE Trial CADDIE Artificial Intelligence Endoscopy
The EAGLE study is a prospective randomized controlled multicenter parallel design trial, for the assessment of clinical performance of the CADDIE device and to confirm that the device performs as expected.
- Conditions
- Colorectal Cancer, Polyp of Colon, Adenoma Colon
- Trial name
- EAGLE (NCT05730192)
- Testing
- Colonoscopy with CADDIE, Standard Colonoscopy
- Where
- 8 sites in Germany, Italy and 2 more
- Volunteers
- 985 people
- Sponsor
- Odin Medical
Cancer
Post Market Evaluation of Aer-O-Scope Visualization
This will be a prospective multi-center, multi-national comparative non-blinded clinical investigation. Each subject will undergo back-to-back tandem colonoscopies with the Aer-O-Scope Colonoscope System and a conventional…
- Trial name
- NCT02926209
- Testing
- Aer-O-Scope (Colonoscopy), Colonoscopy (Conventional Colonoscope)
- Where
- 2 sites in United States, Israel
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- GI View Ltd.
Screening Colonoscopy for Low Risk Subjects
First in Man Aer-O-Scope
A single center study intended to evaluate the Aer-O-Scope Colonoscope System.
- Trial name
- NCT02102412
- Testing
- screening colonoscopy
- Where
- Croatia
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- GI View Ltd.
Colonic Polyp, Colonic Neoplasms
Validation of Aer-O-Scope Colonoscope System Cecal Intubation
61 subjects (male or female) between the ages of 45 and 75 will undergo colonoscopy. The primary outcome is Cecal Intubation
- Conditions
- Colonic Polyp, Colonic Neoplasms, Colonic Diseases, Colon Adenoma
- Trial name
- NCT03949777
- Testing
- Aer-O-Scope Colonoscopy
- Where
- Israel
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- GI View Ltd.