Clinical trials: Screening Colonoscopy
Colonoscopy, Colorectal Cancer Screening
Triton 1.5 Robotic System for Diagnostic Colonoscopy in the Middle East
The purpose of this study is to gain early experience in the Triton 1.5 System in performing diagnostic, screening, surveillance, and basic therapeutic tasks (e.g., polypectomy for lesions ≤ 2 cm).
- Trial name
- CARE-UAE (NCT07835542)
- Testing
- Diagnostic Test: Diagnostic Colonoscopy
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Neptune Medical
Colonoscopy, Colorectal Cancer Screening
Water Exchange Colonoscopy in Elderly Patients
Colonoscopy is an important test for detecting colorectal polyps and cancer, but it can cause pain and discomfort, especially in older adults. Traditional colonoscopy uses air to expand the colon.
- Trial name
- NCT07830823
- Testing
- Water exchange colonoscopy, Gas insufflation colonoscopy, Propofol and opioid anesthesia
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First People's Hospital Of Lin'an District, Hangzhou
Colonoscopy, Colorectal Cancer Screening
Triton 1.5 Robotic System for Diagnostic Colonoscopy
This study is a prospective, single-arm, non-randomized, single-site study, focused on evaluating the safety and efficacy of the Triton 1.5 System in diagnostic and basic therapeutic colonoscopy.
- Trial name
- CARE II (NCT07606963)
- Testing
- Diagnostic Test: Diagnostic Colonoscopy
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Neptune Medical
Colorectal Neoplasia, Screening Colonoscopy
Total Underwater Colonoscopy (TUC) for Improved Colorectal Cancer Screening: A Randomized Controlled Trial
Colorectal cancer (CRC), the third most diagnosed cancer and second most common cause of cancer death. CRCs develop from precursors like adenomas (about 70% of CRCs) or serrated lesions (SSLs) (about 25-30% of CRCs).
- Conditions
- Colorectal Neoplasia, Screening Colonoscopy, Colorectal Cancer, Colorectal Cancer Screening
- Trial name
- NCT06333392
- Testing
- Total underwater colonoscopy, Conventional colonoscopy
- Where
- 5 sites in Norway, Sweden
- Volunteers
- 1,070 people
- Sponsor
- Vestre Viken Hospital Trust
Polyps Colorectal, Colonoscopy
Optical Diagnosis of Neoplasia Using Artificial Intelligence
Computer-aided diagnosis (CADx) for colonoscopy aims to enhance optical diagnosis but often underperforms when used alongside humans due to under-reliance on AI.
- Conditions
- Polyps Colorectal, Colonoscopy, Optical Biopsy, Colorectal Cancer Control and Prevention
- Trial name
- FAIR (NCT07158203)
- Testing
- CADx simultaneously, CADx delayed
- Where
- 2 sites in Norway, Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
Cancer Screening, Chronic Diseases in Older Adults
Pragmatic Mobile Health Trial to Promote Cancer Screening and Healthy Behaviors
Cancer is the leading cause of death in Singapore, but many people who are eligible for breast, cervical, and colorectal cancer screening do not get screened on time.
- Conditions
- Cancer Screening, Chronic Diseases in Older Adults, Early Cancer Detection, Mammography
- Trial name
- mHEALTH (NCT07725328)
- Testing
- Intensive Engagement, Standard Engagement
- Where
- Singapore
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Colonoscopy, Bowel Preparation Solutions
Electrolyte Beverage Combined With Polyethylene Glycol for Colonoscopy Bowel Preparation
This randomized controlled trial aims to evaluate the effects of different ratios of electrolyte beverage and water combined with polyethylene glycol (PEG) on bowel preparation quality before colonoscopy.
- Conditions
- Colonoscopy, Bowel Preparation Solutions, Colorectal Cancer Screening
- Trial name
- NCT07608120
- Testing
- PEG With Water, PEG With Low-dose Electrolyte Beverage, PEG With Medium-dose Electrolyte Beverage
- Where
- China
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Bowel Preparation, Efficacy, Tolerability, Safety, Colon Cancer Screening
Assessment of Safety, Quality, and Acceptance of a Bowel Preparation Using a Food Kit With Laxatives
The main purpose of this research study is to learn if an alternative bowel preparation (bowel prep) for colonoscopy is safe, tolerable and effective as compared to the standard bowel prep.
- Conditions
- Bowel Preparation, Efficacy, Tolerability, Safety, Colon Cancer Screening, Bowel Preparation for Colonoscopy
- Trial name
- NCT07605897
- Testing
- Use of a standardized meal content (food-kit) the day prior to colonoscopy, Polyethylene glycol 3350 - electrolyte solution (GoLYTELY)
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Joseph Spataro
Colorectal Cancer Screening, Colonic Polyps/Colonoscopy/Colorectal Neoplasms
The Impact of Image-Assisted Colonoscope on Patient Experience, Physician Workload, and Examination Quality
Colonoscopy is the cornerstone for colorectal cancer screening, diagnosis, and post-treatment surveillance. Procedural quality is influenced by patient anatomy, particularly variations in colonic configuration such as sigmoid…
- Conditions
- Colorectal Cancer Screening, Colonic Polyps/Colonoscopy/Colorectal Neoplasms, Difficult Colonoscopy, Colonoscopy-Related Discomfort
- Trial name
- LOOP-p1 (NCT07541924)
- Testing
- CT-Based Image-Assisted Colonoscope Insertion
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- DONG WU
Obesity (Body Mass Index &Amp;Amp;gt;30 kg/m2), Screening Colonoscopy
Randomized Controlled Trial Comparing Adult to Pediatric Colonoscope in Obese Patients.
The goal of this study is to test which colonoscope works best in people who are above a certain body mass index. Currently, both pediatric and adult colonoscopes are accepted as standard treatments in colonoscopies.
- Trial name
- NCT06776913
- Testing
- Colonoscopy
- Where
- United States
- Volunteers
- 244 people
- Sponsor
- Cleveland Clinic Florida
Colonoscopy, Screening Colonscopy
What Influence Re-participation in the Danish Colorectal Screening Program.
This prospective observational study investigates how participants experience screening colonoscopy within the Danish colorectal cancer screening program and how these experiences relate to clinical findings, procedural factors…
- Conditions
- Colonoscopy, Screening Colonscopy, Pain
- Trial name
- NCT07353632
- Where
- 8 sites in Denmark
- Volunteers
- 8,000 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Colorectal Cancer Screening, Bowel Cleansing for Colonoscopy
Cleansing Options in Out-Patient Setting to Improve Tolerance (COOP SIT) Trial
The purpose of this research is to compare patient preferences for two bowel preparation options: low-volume tablets (Suflave/Sutab) versus the standard colon preparation using Golytely (polyethylene glycol).
- Trial name
- COOP SIT (NCT07215000)
- Testing
- Golytely, Sulfave, Sutab
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Morehouse School of Medicine
Colonoscopy, Colorectal Cancer Screening
Effect of Counseling and Education on Mechanical Bowel Preparation
The goal of this clinical trial is to learn whether enhanced education and counseling can improve bowel preparation before colonoscopy in high-risk patients.
- Trial name
- EEFEC-AMBP (NCT07093099)
- Testing
- Enhanced Education Package for Bowel Preparation, Standard Education Leaflet
- Where
- Palestinian Territories
- Volunteers
- 150 people
- Sponsor
- Al-Ram Drug Store
Colonoscopy, Colorectal Cancer Screening
Robotic Colonoscopy Using the Triton 4.0 System in Adults for Screening, Surveillance, and Diagnosis of Lower Gastrointestinal Conditions
This study is a prospective, single-arm, non-randomized, single site first-in-human study and will be conducted in two phases, where Phase A will serve to evaluate the safety of the Triton 4.0 System to perform screening…
- Conditions
- Colonoscopy, Colorectal Cancer Screening, Colorectal Neoplasms, Gastrointestinal Endoscopy
- Trial name
- CARE I (NCT06935734)
- Testing
- Diagnostic Colonoscopy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Neptune Medical
Adenoma Detection Rate Improvement in Screening Colonoscopy
Endoscopic Size Assessment of Advanced Adenomatous Polyps
The investigators are retrospectively comparing detection rates of adenomatous polyps, advanced adenomas, and size assessment of the polyps among Rush University Medical Center endoscopists.
- Trial name
- NCT02193646
- Where
- United States
- Volunteers
- 1,930 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Screening Colonoscopy, Surveillance Colonoscopy
Study to Evaluate the Diagnostic Performance of of MAGENTIQ-COLO During Colonoscopy.
This is an international, multicenter, study to evaluate the diagnostic performance of the CADx polyp sizing modality of the MAGENTIQ-COLO.
- Trial name
- NCT06568523
- Testing
- MAGENTIQ-COLO.
- Where
- 5 sites in United States, Israel and 1 more
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Magentiq Eye LTD
Colorectal Cancer Screening, Colonoscopy
Smart Phone App for COLOnoscopic PREParation
This is a randomized controlled trial designed to assess the efficacy of a novel smartphone application as an automated reminder tool in improving the quality of bowel preparation for patients undergoing outpatient colonoscopies.
- Conditions
- Colorectal Cancer Screening, Colonoscopy, Mass Screening
- Trial name
- COLOPREP (NCT03225560)
- Testing
- Bowel Preparation
- Where
- Canada
- Volunteers
- 238 people
- Sponsor
- Sunil Patel
Screening Colonoscopy, Colonoscopic Control After Polypectomy
Study on the Use of Artificial Intelligence (Fujifilm) for Polyp Detection in Colonoscopy
Colonoscopy is currently the best method of detection of intestinal tumors and polyps, particularly because polyps can also be biopsied and removed.
- Conditions
- Screening Colonoscopy, Colonoscopic Control After Polypectomy, Suspected Colon Polyps
- Trial name
- Fuji AI (NCT04894708)
- Testing
- colonoscopy
- Where
- 10 sites in Germany
- Volunteers
- 1,572 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Screening Colonoscopy
Effect of Real-time Computer-aided System (ENDO-AID) on Adenoma Detection in Endoscopist-in-training
The investigator's hypothesis is that a CADe system (ENDO-AID) would improve the adenoma detection rate in junior endoscopists.
- Trial name
- ENDOAIDTRAIN (NCT04838951)
- Testing
- ENDO-AID CADe
- Where
- Hong Kong
- Volunteers
- 856 people
- Sponsor
- Chinese University of Hong Kong
Screening Colonoscopy, Surveillance Colonoscopy
A Study to Evaluate the Safety and Efficacy of the Use of ME-APDS During Colonoscopy
ME-APDS is a device (software-based with hardware) developed by Magentiq Eye LTD and intended to support the decision of the endoscopist on polyps which appear in the colonoscopy video during the colonoscopy procedure.
- Trial name
- NCT04640792
- Testing
- Screening or Surveillance Conventionall colonoscopy
- Where
- 11 sites in United States, Germany and 2 more
- Volunteers
- 952 people, healthy volunteers welcome
- Sponsor
- Magentiq Eye LTD