Clinical trials: Scarring
Scarring
Dehydrated Human Amnion/Chorion Membrane (dHACM) for Recovery After Fractionated Ablative CO2 Laser Resurfacing of the Face
The purpose of this study is to evaluate the efficacy of dHACM (Dehydrated Human Amnion Chorion Membrane) for reducing time to healing when used in post-laser recovery following ActiveFX™ and DeepFx™ fractionated ablative CO2…
- Trial name
- NCT01995604
- Testing
- Application of Sterile 0.9% Saline Solution, Application of dHACM
- Where
- United States
- Sponsor
- MiMedx Group, Inc.
Wrinkle, Rosacea
Evaluation of Cutera Excel V™ Laser With Green Genesis and Micro-Lens Array (MLA)Attachment
Evaluate the Cutera excel V™ Laser with Green Genesis and a Micro-Lens Array (MLA) Attachment
- Conditions
- Wrinkle, Rosacea, Scarring
- Trial name
- NCT03424304
- Testing
- Excel V™ Laser With Green Genesis
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Pregnancy, Cesarean Section
Vaginal Birth After Caesarean Section - Effect on Maternal Psychosocial Function
The incidence of caesarean section has reached 15-20% in most developed countries. Encouraging vaginal birth after caesareans section (VBAC) has been considered a key component of a strategy to reduce the caesarean section rate.
- Conditions
- Pregnancy, Cesarean Section, Uterine Rupture
- Trial name
- NCT00517140
- Testing
- Repeat Caesaen section, vaginal delivery
- Where
- China
- Volunteers
- 262 people
- Sponsor
- Hospital Authority, Hong Kong
Keloid, Stem Cell
Comparison of Keloid Volume and Symptoms Reduction Between Intralesional Umbilical-Cord Mesenchymal Stem Cells, Its Conditioned Medium, and Triamcinolone Acetonide Injection as Keloid Therapy: A Randomised Controlled Trial
This study is a double-blind randomized controlled trial (RCT) examining the effect of intralesional injection of umbilical cord-derived mesenchymal stem cells (UC-MSC), umbilical cord-derived conditioned medium (UC-CM), or…
- Trial name
- NCT05887804
- Testing
- umbilical cord-derived mesenchymal stem cells (UC-MSC), umbilical cord-derived mesenchymal stem cells conditioned medium (UC-CM), Triamcinolone Acetonide (TA)
- Where
- Indonesia
- Volunteers
- 24 people
- Sponsor
- Rumah Sakit Pusat Angkatan Darat Gatot Soebroto
Cesarean Section Complications
Evaluation Of The Diagnostic Role Of Hysterosalpingography In Cesarean Scar Niche Diagnosed By Hysteroscopy
The term CS niche (defect) describes the presence of a hypoechoic area within the myometrium in the isthmus (lower uterine segment) with discontinuation of myometrium at the site of previous CS.
- Trial name
- NCT05911815
- Testing
- hysterosalpingography
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Burns, Burn Scar
PORCINE XENOGRAFT OR MICROBIAL CELLULOSE IN THE TREATMENT OF PARTIAL THICKNESS BURNS
The purpose of this study was to compare two wound dressing products for partial thickness burns in adults.
- Conditions
- Burns, Burn Scar, Burn Second Degree
- Trial name
- NCT04412759
- Testing
- microbial cellulose
- Where
- Sweden
- Volunteers
- 26 people
- Sponsor
- University Hospital, Linkoeping
Suture; Complications, Mechanical, Scar
Comparing 1 Week Versus 2 Week Cutaneous Suture Removal
Our goal is to compare the difference in surgical outcomes and patient satisfaction for surgical scars on the face between suture removal at 1 week versus 2 weeks.
- Conditions
- Suture; Complications, Mechanical, Scar, Surgery
- Trial name
- NCT05267002
- Testing
- Suture removal timing
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- DermSurgery Associates
Hypertrophic Scar
Safety, Tolerability, Pharmacokinetics, Immunogenicity and Efficacy of STP705 in Adult Patients With Hypertrophic Scars
Adult patients with hypertrophic scars 30 Subjects in Dose Escalation 20 Subjects in Dose Expansion Intrascar injection of STP705 weekly for 4 weeks
- Trial name
- NCT05196373
- Testing
- STP705
- Where
- China
- Sponsor
- Sirnaomics
Keloid
Retrospective Study of Keloid Disorder
Purpose of this retrospective study is to review and analyze the information and data that has been already been generated during the course of routine practice of medicine by the investigators from 2007 up until Sept 1, 2016…
- Trial name
- NCT02923596
- Testing
- History of prior Surgery, History of Radiation Therapy
- Where
- 2 sites in United States
- Volunteers
- 5,000 people
- Sponsor
- Tirgan, Michael H., M.D.
Scar Tissue, Hypertrophic Scar
Effectiveness of Dry Needling in Linear Scar Tissue
Scar tissue can cause serious complications that significantly impact a patient's quality of life. Common complications include stiffness and contractions, which can restrict joint mobility and make daily activities challenging.
- Conditions
- Scar Tissue, Hypertrophic Scar, Hypertrophic Scar of Upper Arm (Disorder), Hypertrophic Surgical Scar
- Trial name
- NCT06033430
- Testing
- True dry needling
- Where
- 2 sites in United States, Iran
- Volunteers
- 80 people
- Sponsor
- Iran University of Medical Sciences
Healthy
Investigational Air-Activated Adhesive-Backed Heat Patch (3-Cell)
This is an open-label study. A total of approximately 60 subjects will be randomly assigned to receive either the heat patch (30 subjects) with a temperature probe/skin reference probe or a heat patch (30 subjects) alone.
- Trial name
- NCT02241057
- Testing
- Investigational Air-Activated Adhesive-Backed Heat Patch (3-Cell), Temperature Probe
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chattem, Inc.
Cicatrix
Safety and Efficacy of RN1001(Avotermin) in Healthy Male Subjects
A double blind, Placebo (Vehicle) and Standard Care controlled, randomised study to investigate the clinical safety and toleration (including systemic pharmacokinetics), wound healing and antiscarring potential of two…
- Trial name
- NCT00847925
- Testing
- Avotermin (RN1001)
- Where
- United Kingdom
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Renovo
Burn Scar, Hypertrophic Scar
Characterization of Dyschromic Hypertrophic Scar
Currently, there are limited prevention or treatments available for dyschromia in burn hypertrophic scars (HTSs). The limited available techniques involve transferring melanocytes from unaffected areas to the scar to adjust…
- Conditions
- Burn Scar, Hypertrophic Scar, Hyperpigmentation, Hypopigmented Scar
- Trial name
- NCT04619589
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Medstar Health Research Institute
Burns, Scars
The Technique of Skin Stretching for Acute Burn Treatment and Scar Reconstruction
Objective: A randomized controlled trial is performed to evaluate the clinical effectiveness of the skin stretching technique for two categories: 1.
- Trial name
- NCT00609908
- Testing
- Split skin graft, skin stretching device, serial excision
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Association of Dutch Burn Centres
Cosmetics, Suture, Cicatrix
Polyglactin 910 vs Poligelecaprone 25 Running Subcuticular Closure of Elliptical Excision Wounds
We will be recruiting patients requiring excisions of skin cancer and comparing aesthetic and functional differences of suture repair of excisional defects using polyglactin 910 vs poliglecaprone 25 with a split-scar model.
- Trial name
- NCT02776618
- Testing
- running subcuticular closure of excisional defect
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Cesarean Scar Pregnancy, Menstruation
Outcome After MTX & Transvaginal Surgery or UAE & Uterine Curettage in Patients With Cesarean Scar Pregnancy
Cesarean scar pregnancy (CSP)is one of the more serious complications of pregnancies that occur after a prior cesarean delivery. No clinical guidelines have been issued for the management of CSP.
- Trial name
- NCT03218059
- Testing
- Methotrexate Combined With Transvaginal Surgery
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Cardiomyopathies, Ventricular Dysfunction
Measuring Electrical Resistance of Different Tissues on the Outer Surface of the Heart
This is a research study to evaluate the electrical properties of heart tissue. The purpose of this study is to determine the impedance (electrical resistance) of different tissues on the outer surface of the heart.
- Conditions
- Cardiomyopathies, Ventricular Dysfunction, Myocardial Infarction, Arrhythmia
- Trial name
- NCT00291174
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Pennsylvania
COVID-19, Virus Disease
Prevalence of Myocardial Scars on CMR After COVID-19 Infection
The aim of this study is to assess the prevalence and arrhythmogenic role of occult myocardial scars on Cardiac Magnetic Resonance (CMR) in a population of patients with history of laboratory-proven symptomatic COVID-19 infection…
- Trial name
- COVID-CMR (NCT04636320)
- Testing
- Contrast-enhanced CMR, Exercise test ECG, Blood sample
- Where
- France
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Ventricular Tachycardia
Safety and Effectiveness of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere VT)
Sphere VT is a prospective, multi-center, single-arm, unblinded pivotal clinical study. Adult subjects with recurrent, sustained, monomorphic ventricular tachycardia (MMVT) due to prior myocardial infarction (MI) will be enrolled…
- Trial name
- NCT07585968
- Testing
- Sphere-9 Catheter with the Affera Mapping and Ablation System
- Where
- 7 sites in United States
- Volunteers
- 260 people
- Sponsor
- Medtronic Cardiac Ablation Solutions
Burn Scar
Fat Grafting in Skin-grafted Deep Burn Scars
fat grafting in human skin-grafted immature burn scars histological, clinical and photographic follow-up
- Trial name
- NCT03627650
- Testing
- lipofilling/ fat grafting
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
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