Clinical trials: Sarcopenia in Elderly
Sarcopenia in Elderly, Chronic Heart Failure
Effects of Resistance Training on Sarcopenia in Older Patients With Chronic Heart Failure
The goal of study is to evaluate the effects of an eight-week machine-based resistance training program on managing sarcopenia in older outpatients with chronic heart failure (HF) at Military Hospital 175.
- Trial name
- NCT06785168
- Testing
- Machine-based Resistance Training
- Where
- 2 sites in Vietnam
- Volunteers
- 146 people
- Sponsor
- Kieu Dang Phuong Nguyen
Inactivity, Physical, Treatment Adherence and Compliance
VR vs. Conventional Cycling Exercise for Geriatric Inpatient Physical Activation
The aim of this study is to investigate whether virtual reality assisted stationary cycling exercise results in more physical activity than conventional unsupervised stationary cycling exercise.
- Conditions
- Inactivity, Physical, Treatment Adherence and Compliance, Hospital Acquired Condition, Sarcopenia
- Trial name
- NCT05123638
- Testing
- Virtual reality cycling exercise, Unsupervised stationary cycling exercise
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Bispebjerg Hospital
Aging, Sarcopenia
Effects of Whole-body Electrical Muscle Stimulation Exercise on Spinal Motoneuronal Activation in Older Adults
During this pilot study, the investigators will examine the effects of whole-body electrical muscle stimulation exercise (WB-EMS Exercise) on motoneuronal activation in healthy adults, which typically decreases with age.
- Conditions
- Aging, Sarcopenia, Sarcopenia in Elderly
- Trial name
- NCT06689618
- Testing
- Exercise
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Possible Sarcopenia
Exercise Snacks for Muscle Strength in Older Adults With Possible Sarcopenia
This study aims to investigate whether exercise snacks, a time-efficient approach involving short bouts of exercise performed throughout the day, can improve muscle strength in older adults with possible sarcopenia.
- Trial name
- NCT07821164
- Testing
- Exercise Snacks, Home-based Resistance Training
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ziren Zhao
Sarcopenia
Creatine-Guanidinoacetic Acid Supplementation for Sarcopenia (CREGAAS)
Sarcopenia-driven brain and muscle creatine deficit could be seen as a distinctive pathological facet of this condition, and this might be approached with targeted therapies in aim to restore creatine homeostasis in target…
- Trial name
- CREGAAS (NCT04652921)
- Testing
- Creatine-guanidinoacetic acid, Inulin
- Where
- Serbia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Aging, Muscular Atrophy
Maximizing Mechanisms of Muscle Hypertrophy to Combat Sarcopenia in Older Adults
Resistance training has shown the most promise among interventions aimed to combat aging muscle atrophy as it enhances strength, power, and mobility function, but induces varying degrees of skeletal muscle hypertrophy as the…
- Trial name
- NCT02442479
- Testing
- resistance training
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Sarcopenia, Osteoporosis
The Effect of Bovine Colostrum Supplementation in Older Adults
Bovine colostrum is the initial milk secreted by cows during the first day after calving. Colostrum is high in protein and contains a number of substances that have potential to be beneficial for the immune system.
- Trial name
- NCT01792297
- Testing
- Bovine colostrum, Whey protein
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Sarcopenia
Balance Trainning for Sarcopenic Inpatients Aged 80+ Years
Resistance training and aerobic exercise have been recommended for sarcopenic patients. However, whether balance training would further benefit for sarcopenic patients on the basis of resistance training and aerobic exercise…
- Trial name
- NCT04216368
- Testing
- balance training, resistance training
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Yuxiang Liang
Sarcopenia
Calf Circumference Versus X-ray Absorptiometry in the Diagnosis of Sarcopenia in Elderly Hospitalized Patients
This is a prospective single-center study to evaluate a diagnostic method. The main objective of the study is to evaluate the performance of calf circumference as a diagnostic method for sarcopenia in hospitalized elderly people…
- Trial name
- PAPY-SARCM (NCT05869487)
- Testing
- Dual-energy X-ray absorptiometry
- Where
- France
- Volunteers
- 298 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Sarcopenia
Effect of Nutrition Supplementation Combined With Resistance Exercise in Elderly With Sarcopenia.
The purpose of this study was determine whether milk or soy milk supplements combined with resistance exercise improved sarcopenia in the elderly.
- Trial name
- NCT05035121
- Testing
- milk supplement, soy milk supplement, resistance exercise
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Sarcopenia
Assessing the Dose-response of Muscle Protein Synthesis to "Super-whey" in Older Adults
Skeletal muscle accounts for approximately 45-55% of total body mass in healthy adults and plays a pivotal role in whole-body metabolic health, locomotion and physical independence.
- Trial name
- ARLA-WHEY (NCT05700058)
- Testing
- Dietary protein supplement
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
The Association Between Sarcopenia and the Strength of Peripheral and Respiratory Muscles in Elderly Individuals, Cardiovascular Diseases
The Association Between Sarcopenia and the Strength of Peripheral and Respiratory Muscles in Elderly Individuals
Population aging is a significant global trend, with projections indicating that by 2050, 1 in 6 individuals worldwide will be over 65 years old, compared to 1 in 11 in 2019.
- Conditions
- The Association Between Sarcopenia and the Strength of Peripheral and Respiratory Muscles in Elderly Individuals, Cardiovascular Diseases, Diabetes Mellitus, Hypertension
- Trial name
- NCT06756399
- Testing
- Questionnare, hand grip and respiratory muscle strength
- Volunteers
- 100 people
- Sponsor
- Biruni University
Sarcopenia in Elderly
THE EFFECT OF PROPRIOCEPTIVE EXERCISE TRAINING ON CERVICAL PROPRIOCEPTION, KINESIOPHOBIA, AND PAIN CATASTROPHIZING LEVELS IN SARCOPENIC GERIATRIC INDIVIDUALS RESIDING IN NURSING HOMES
This study investigated the effects of cervical proprioceptive exercise training on cervical proprioception, kinesiophobia and pain catastrophising in sarcopenic nursing home residents.
- Trial name
- NCT07253714
- Testing
- Classic exercises, Proprioceptive exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Atılım University
Sarcopenia
Nutritional Intervention for Sarcopenia
Sarcopenia is an age-related poor healthy outcome. nutrition intervention is one , progressive, generalized loss of muscle mass and the decrement in physical activity.
- Trial name
- NCT03891134
- Testing
- Branched Chain Amino Acid
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Chimei Medical Center
Sarcopenia
Understanding Acute Sarcopenia
This study aims to characterise acute changes in muscle mass, strength, physical performance in hospitalised older adults. We will assess the impact of these changes upon physical function at three month follow-up, and assess for…
- Trial name
- NCT03858192
- Testing
- Colorectal surgery procedure, Emergency abdominal surgery, Antibiotics
- Where
- United Kingdom
- Volunteers
- 168 people
- Sponsor
- University of Birmingham
Browning of Subcutaneous White Adipose Tissue Post Intervention, Metabolic and Inflammatory Variables Post Intervention
Taurine Supplementation Associated or Not With Exercise: Effect on Browning of White Adipose Tissue in Elderly Women With Sarcopenic Obesity
The aging process is followed by metabolic and body composition changes, increasing the risk of obesity and sarcopenia. The coexistence of these conditions acts synergistically on each other and is known as sarcopenic obesity.
- Trial name
- NCT05415176
- Testing
- Taurine supplementation, Pshysical exercise
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Elderly, Metabolic Syndrome
Metabolic Syndrome and Vitamin D Level in Old People
In 2012, a cross-sectional survey sampling 1,966 community-dwelling old people was conducted. Structurized questionnaires were interviewed face-to-face by well-trained staffs.
- Conditions
- Elderly, Metabolic Syndrome, Vitamin D Deficiency, Ostreocalcin
- Trial name
- NCT03344718
- Where
- Taiwan
- Volunteers
- 549 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Sarcopenia, Dietary Exposure
Impact of Diet on the Gut-Muscle Axis in Older Adults
Muscle health declines during aging. One factor that may impact muscle health is the community of bacteria that live in our intestines, but studies aimed at improving muscle health by targeting the gut in older adults are sparse.
- Conditions
- Sarcopenia, Dietary Exposure, Microbial Colonization
- Trial name
- NCT05549622
- Testing
- Low-soluble fiber diet, High-soluble fiber diet
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Tufts University
Postoperative Delirium, Sarcopenia
Effect of Preoperative Sarcopenia on Postoperative Delirium in Elderly Patients Undergoing Gastrointestinal Surgery
The goal of this observational study is to compare Incidence of postoperative delirium in Sarcopenic and non-sarcopenic elderly patients undergoing gastrointestinal surgery.
- Conditions
- Postoperative Delirium, Sarcopenia, Gastrointestinal Surgery, Anesthesia
- Trial name
- NCT05847296
- Where
- China
- Volunteers
- 334 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Sarcopenia, Gait Disorders in Old Age
A Double-blind, Placebo-controlled, Randomized INTerventional Clinical Trial (SARA-INT)
The main objective of the study is to evaluate the effect of two daily doses of BIO101 versus placebo on mobility function as measured by gait speed using the 400MW test.
- Conditions
- Sarcopenia, Gait Disorders in Old Age, Muscle Weakness
- Trial name
- SARA-INT (NCT03452488)
- Testing
- BIO101
- Where
- 22 sites in United States, Belgium
- Volunteers
- 233 people
- Sponsor
- Biophytis