Clinical trials: Sacroiliitis
Sacroiliitis, Sacroiliac Joint Dysfunction
Post-Market Clinical Study on a Modular SI Joint Fusion System
A prospective study on the use of the TransLoc 3D SI Joint Fusion System for patients with sacroiliac joint disruptions or degenerative sacroiliitis.
- Trial name
- SPARTAN (NCT05916092)
- Testing
- TransLoc 3D
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- CornerLoc
Arthritis, Spondylitis, Ankylosing
Natural History and Development of Spondyloarthritis
Background: Spondyloarthritis (SpA) is a group of bone and joint disorders that may cause back and joint pain and stiffness. In some cases, SpA can lead to abnormal bone growth affecting the joints and spine.
- Trial name
- NCT01422694
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Non-radiographic Axial Spondyloarthritis
A Study of Secukinumab to Evaluate Maintenance of Response in Participants With Non-radiographic Axial Spondyloarthritis Who Achieved Remission
This study will establish whether prolonged chronic dosing with secukinumab is needed in participants with Non-radiographic axial spondyloarthritis, (nr-axSpA) who have achieved remission.
- Trial name
- NCT05622708
- Testing
- Secukinumab
- Where
- 61 sites in Belgium, Brazil and 16 more
- Volunteers
- 240 people
- Sponsor
- Novartis Pharmaceuticals
Sacroiliitis, Sacroiliac; Fusion
Evaluation of the iFuse Bedrock Technique in Association With Posterior Lumbosacral Fusion With Iliac Fixation.
The purpose of this study is to describe the impact of the iFuse Bedrock technique to decrease post-operative pains in patients who underwent multilevel posterior lumbosacral fusion.
- Conditions
- Sacroiliitis, Sacroiliac; Fusion, Lumbosacral; Fusion, Spine Deformity
- Trial name
- NCT05276024
- Testing
- iFuse Bedrock technique
- Where
- 2 sites in France
- Volunteers
- 48 people
- Sponsor
- Polyclinique Bordeaux Nord Aquitaine
Degenerative Sacroiliitis, Sacroiliac Disorder
Sacroiliac Joint Fusion Intervention For Mobility, Pain Relief, and Lasting Improvement in Functional Recovery "SIMPLIFY"
The purpose of this study is to determine the clinical efficacy of The Trellis SI Joint Fusion System in unilateral sacroiliac (SI) joint fusion surgeries.
- Trial name
- SIMPLIFY (NCT07849244)
- Testing
- TRELLIS SI Joint Fusion System
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- OrthoFundamentals, LLC
Sacroiliitis
Outcomes of Intra-articular Steroid Injection Via Ultrasound Guidance Versus Fluoroscopic Guidance in the Sacroiliac Joint in Patients With Sacroiliitis
Sacroiliitis is a common cause of low back and buttock pain. Intra-articular steroid injection of the sacroiliac joint can provide pain relief and functional improvement.
- Trial name
- NCT07791108
- Testing
- Ultrasound-guided intra-articular steroid injection
- Where
- Pakistan
- Volunteers
- 176 people
- Sponsor
- Allied Hospital Faisalabad
Sacroilitis
Laser Therapy in the Isotretinoin-Induced Sacroiliitis
The clinical significance of this adverse effect lies in its impact on quality of life and the potential for misdiagnosis. The symptomatology can be severe enough to limit daily activities and may be mistakenly attributed to a…
- Trial name
- NCT07264153
- Testing
- Laser Therapy, Exercises for both groups
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Uşak University
Chronic Pain, Sacroiliitis
Conventional Sacroiliac Joint Injection Versus Pulsed Radiofrequency in SIJ Pain
Therapeutic options for SIJ pain include intra-articular corticosteroid injections, which provide symptomatic relief but typically require repeated administration due to variable and short-lived efficacy.
- Trial name
- NCT07709689
- Testing
- Conventional injection, Pulsed radiofrequency (PRF)
- Volunteers
- 80 people
- Sponsor
- National Cancer Institute, Egypt
Sacro Iliac Joint Pain, Sacro-iliac Joints
Posterior-Inferior Intra-articular Cortical Piercing Titanium Implant for Sacroiliac Joint Fusion: Evaluation of Safety and Effectiveness Outcomes
The purpose of this study is to evaluate outcomes in patients treated with iFuse INTRA Ti for chronic SI joint pain.
- Conditions
- Sacro Iliac Joint Pain, Sacro-iliac Joints, Sacroiliac Disorder, Sacroiliac Joint Dysfunction
- Trial name
- PIERCE (NCT07565545)
- Testing
- iFuse INTRA Ti Implant System
- Volunteers
- 120 people
- Sponsor
- SI-BONE, Inc.
Sacroiliitis, Low Back Pain
Neurolyser XR for the Treatment of Sacroiliitis
Our study aims to investigate the safety and efficacy of high intensity focused ultrasound in the management of low back pain due to sacroiliitis.
- Trial name
- NCT07647757
- Testing
- Patients treated with high intensity focused ultrasound
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Federico II University
Sacro Iliac Joint Pain, Sacroiliac Disorder
Gong's Mobilization and Jone's Positional Release for SIJ Dysfunction
This study aims to compare the efficacy of Gong's mobilization and Jones's positional release technique in individuals with sacroiliac joint dysfunction.
- Conditions
- Sacro Iliac Joint Pain, Sacroiliac Disorder, Sacroiliac Joint Dysfunction
- Trial name
- NCT07580430
- Testing
- Gong's mobilization, Jone's positional release
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Elite College of Management Sciences, Gujranwala, Pakistan
Rheumatoid Arthritis, Palindromic Arthritis
Rheumatology-based Adaptive Intervention for Social Determinants and Health Equity
Social determinants of health (SDoH), defined by the World Health Organization as "the conditions in which people are born, grow, work, live and age and the wider set of forces and systems shaping the conditions of daily life"…
- Conditions
- Rheumatoid Arthritis, Palindromic Arthritis, Juvenile Rheumatoid Arthritis, Ankylosing Spondylitis
- Trial name
- RAISE (NCT05715463)
- Testing
- Resource sheets, Community Resource Specialist, Nurse Navigator
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Brigham and Women's Hospital
Sacroiliitis
Use of the Neurolyser XR for the Treatment of Low Back Pain Related to Sacroiliitis
The Neurolyser XR is a device used to deliver high-intensity focused ultrasound for the ablation of the lateral sacral branch nerve in patients with Sacroiliitis.
- Trial name
- NCT06053255
- Testing
- High-intensity focused ultrasound for Sacroiliitis using the Neurolyser XR
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- FUSMobile Inc.
Rheumatoid Arthritis (RA, Psoriatic Arthritis (PsA
Efficacy Of Upadacitinib In Psoriatic Arthritis And Comparison To Rheumatoid Arthritis.
The general objective of the OPTIMA study is to assess the time course and interrelationship of imaging (ultrasound and magnetic resonance imaging), clinical, laboratory, and Patient Reported Outcome variables in patients with…
- Trial name
- OPTIMA (NCT06630715)
- Testing
- Upadacitinib 15 MG [Rinvoq]
- Where
- 14 sites in Italy
- Volunteers
- 178 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Spondyloarthritis
Value of Whole-body SPECT-CT CzT-based Camera (VERITON-CT) in the Assessment of Chronic Inflammatory Rheumatism With Axial Involvement
The diagnosis of chronic inflammatory rheumatism with axial involvement is not always easy, and is fraught with difficulties : radiological sacroiliitis is not an early sign of spondyloarthritis and the delay in detecting…
- Trial name
- ASOCE (NCT06198361)
- Where
- France
- Volunteers
- 47 people
- Sponsor
- Central Hospital, Nancy, France
Sacroiliitis
Significance and Outcome of Magnetic Resonance Enterography Revealing Sacroiliitis in Crohn's Disease: A Pilot Study
This study aims to further define and characterize imaging findings of possible sacroiliitis in Crohn's Disease patients by recalling subjects who had findings of possible sacroiliitis on prior MRE and assess the natural history…
- Trial name
- NCT05203926
- Testing
- MRI scan
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- NYU Langone Health
Ankylosing Spondylitis
Study to Demonstrate the Efficacy, Safety and Tolerability of an Intravenous Regimen of Secukinumab Compared to Placebo in Subjects With Active axSpA
The purpose of this global study was to demonstrate the efficacy, safety, and tolerability of an intravenous (i.v.) regimen of secukinumab compared to placebo in participants with active ankylosing spondylitis (AS) or…
- Trial name
- NCT04156620
- Testing
- Secukinumab
- Where
- 102 sites in United States, Belgium and 16 more
- Volunteers
- 527 people
- Sponsor
- Novartis Pharmaceuticals
Sacroiliac Joint Disruption, Degenerative Sacroiliitis
Post-Market Feasibility Study of the Tenon Medical CATAMARAN™ SI Joint Fusion System
The purpose of this study is to evaluate the outcomes of patients with sacroiliac joint pain treated with the CATAMARAN SI Joint Fusion System.
- Trial name
- NCT05633888
- Testing
- CATAMARAN SI Joint Fusion System
- Where
- 6 sites in United States
- Volunteers
- 50 people
- Sponsor
- Tenon Medical
Sacroiliitis
Frequency of Sacroiliitis in Inflammatory Bowel Disease Patients Using MRI
1. to determine the overall frequency of Inflammatory sacroiliitis among patients with Inflammatory bowel disease using magnetic resonance imaging 2.
- Trial name
- NCT06034808
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Sacroiliitis
Safety and Feasibility of the NeurolyserXR for Sacroiliac Joint Pain
Pilot study to evaluate the safety and the effectiveness of the Neurolyser XR as a treatment for sacroiliitis
- Trial name
- NCT05396495
- Testing
- NeurolyserXR
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- FUSMobile Inc.