Chronic PainNCT07709689
Conventional Sacroiliac Joint Injection Versus Pulsed Radiofrequency in SIJ Pain
A study testing Conventional injection and Pulsed radiofrequency (PRF) in people with Chronic Pain and Sacroiliitis, run by National Cancer Institute, Egypt.
Trial summary
Therapeutic options for SIJ pain include intra-articular corticosteroid injections, which provide symptomatic relief but typically require repeated administration due to variable and short-lived efficacy. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Chronic Pain, Sacroiliitis
- What is being tested?
- Conventional injection and Pulsed radiofrequency (PRF)
- Type of treatment
- Injection or infusion, Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 80 participants
- Where
- No sites listed yet
- Study dates
- 12 Jul 2026to Sep 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Sacroiliac Joint (SIJ) Pain
- Diagnostic Block Response: Demonstrated a pain reduction of at least 50% following a diagnostic intra- articular SIJ block.
- Failure of Medical Management
- Chronic Pain Duration: Presence of chronic pain for a minimum duration of 6 months.
- Pain Intensity: A pain intensity score greater than 5 on a 10-point Numeric Rating Scale (NRS), where 0 represents no pain and 10 represents the worst imaginable pain.
- Age: Aged between 18 and 65 years.
- Body Mass Index (BMI): A BMI within the range of 20 kg/m² to 35 kg/m².
Who cannot join
- Patient refusal.
- Local infection at the puncture site.
- Coagulopathies with platelets count below 50,000 or an INR>1.6.
- Unstable cardiovascular disease and Poor general condition and severe respiratory distress.
- History of psychiatric and cognitive disorders or opioid addiction.
- Patients are allergic to medication used.
- Previous surgery to the affected site.
- Rheumatological disease such as rheumatoid arthtritis or ankylsoing spondyolitis.
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Unlocking Sacroiliac Joint Pain: A Comparative Study of Pulsed Radiofrequency and Conventional Technique
Therapeutic options for SIJ pain include intra-articular corticosteroid injections, which provide symptomatic relief but typically require repeated administration due to variable and short-lived efficacy.
More recently, pulsed radiofrequency (PRF) has been investigated for joint pain management through intra-articular electrode placement and stimulation. However, its effectiveness in treating SIJ pain remains insufficiently studied and warrants further exploration.
- Conditions
- Chronic Pain, Sacroiliitis
- Being tested
- Conventional injection, Pulsed radiofrequency (PRF)
- Medical subject headings
- Chronic Pain, Sacroiliitis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Conventional injectionProcedure or surgery
Sacroiliac joint (SIJ) steroid injection
Pulsed radiofrequency (PRF)Procedure or surgery
PRF of Sacroiliac Joint (SIJ)
| Study group | Role | What they receive |
|---|---|---|
| Conventional injection | Active comparator | Particulate steroid injection in SIJ Receives: Procedure: Conventional injection |
| Pulsed radiofrequency of SIJ | Experimental | Pulsed radiofrequency of SIJ Receives: Procedure: Pulsed radiofrequency (PRF) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Numeric rating score (NRs) reduction
Numeric rating score (NRs) reduction of pain scores after 1 month
Measured: 1 month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Jul 2026
- Study start12 Jul 2026 (estimated)
- Primary completionAug 2027 (estimated)
- Study completionSep 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Chronic PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 80 participants (estimated)
Sponsor and investigators
- Lead sponsor
- National Cancer Institute, Egypt
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Walaa Youssef Elsabeeny, National Cancer Institute, Egypt
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07709689
- Sponsor's protocol ID
- AP2603-501-165-208
- Status last verified
- Jul 2026
- First submitted
- 12 Jul 2026
- Last updated
- 16 Jul 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 16 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Unlocking Sacroiliac Joint Pain: A Comparative Study of Pulsed Radiofrequency and Conventional Technique
- ClinicalTrials.gov ID
- NCT07709689
- Acronym / sponsor ID
- AP2603-501-165-208
- Conditions
- Chronic Pain, Sacroiliitis
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 80 participants (estimated)
- Lead sponsor
- National Cancer Institute, EgyptUniversity, hospital or other
- Study start
- 12 Jul 2026 (estimated)
- Primary completion
- Aug 2027 (estimated)
- Study completion
- Sep 2027 (estimated)
- First posted
- 16 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Therapeutic options for SIJ pain include intra-articular corticosteroid injections, which provide symptomatic relief but typically require repeated administration due to variable and short-lived efficacy.
More recently, pulsed radiofrequency (PRF) has been investigated for joint pain management through intra-articular electrode placement and stimulation. However, its effectiveness in treating SIJ pain remains insufficiently studied and warrants further exploration.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Conventional injection | Active comparator | Procedure: Conventional injectionParticulate steroid injection in SIJ |
| Pulsed radiofrequency of SIJ | Experimental | Procedure: Pulsed radiofrequency (PRF)Pulsed radiofrequency of SIJ |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (7 listed)
- Sacroiliac Joint (SIJ) Pain
- Diagnostic Block Response: Demonstrated a pain reduction of at least 50% following a diagnostic intra- articular SIJ block.
- Failure of Medical Management
- Chronic Pain Duration: Presence of chronic pain for a minimum duration of 6 months.
- Pain Intensity: A pain intensity score greater than 5 on a 10-point Numeric Rating Scale (NRS), where 0 represents no pain and 10 represents the worst imaginable pain.
Key exclusion criteria (8 listed)
- Patient refusal.
- Local infection at the puncture site.
- Coagulopathies with platelets count below 50,000 or an INR>1.6.
- Unstable cardiovascular disease and Poor general condition and severe respiratory distress.
- History of psychiatric and cognitive disorders or opioid addiction.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Conventional injectionSacroiliac joint (SIJ) steroid injection | Procedure or surgery | Conventional injection |
| Pulsed radiofrequency (PRF)PRF of Sacroiliac Joint (SIJ) | Procedure or surgery | Pulsed radiofrequency of SIJ |
Primary outcome
Numeric rating score (NRs) reduction
Time frame: 1 month
Numeric rating score (NRs) reduction of pain scores after 1 month
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Jul 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing Conventional injection and Pulsed radiofrequency (PRF) in people with Chronic Pain and Sacroiliitis, run by National Cancer Institute, Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 16 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Walaa Y Elsabeeny, MD (01007798466, walaa.elsabeeny@nci.cu.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Numeric rating score (NRs) reduction (time frame: 1 month). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Jul 2026.