Clinical trials: SCAD, open to volunteers
Spontaneous Coronary Artery Dissection, SCAD
Genetic Investigations in Spontaneous Coronary Artery Dissection (SCAD)
The purpose of the research is to identify mutations (defects in the genetic blueprint) that cause spontaneous coronary artery dissection (SCAD), in other words, spontaneous tears in blood vessels that supply the heart.
- Trial name
- NCT01427179
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Spontaneous Coronary Artery Dissection
Randomized Study of Beta-Blockers and Antiplatelets in Patients With Spontaneous Coronary Artery Dissection
Spontaneous coronary artery dissection (SCAD) is a cause of acute coronary syndrome (ACS). Most patients are treated with beta-blockers (BB) and antiplatelet drugs (AP) on empiric basis.
- Trial name
- BA-SCAD (NCT04850417)
- Testing
- Beta blocker, aspirin, clopidogrel
- Volunteers
- 600 people
- Sponsor
- Spanish Society of Cardiology
Spontaneous Coronary Artery Dissection
Spontaneous Coronary Artery Dissection (SCAD) Avatar Study
The purpose of this study is to evaluate patient satisfaction, comfort, and trust in interacting with an avatar compared with speaking to a human clinician during a pre clinical visit.
- Trial name
- NCT07497633
- Testing
- Video Avatar Interview, Voice-Only Avatar Interview, Human Interview
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Mayo Clinic
SCAD, Myocardial Infarction (MI)
Norwegian Spontaneous Coronary Artery Dissection Study
The Norwegian Spontaneous Coronary Artery Dissection Study (NOR-SCAD) is a national, multicenter prospective observational study conducted at major hospitals in Norway.
- Conditions
- SCAD, Myocardial Infarction (MI), Women
- Trial name
- NOR-SCAD (NCT07317323)
- Where
- 3 sites in Norway
- Volunteers
- 300 people
- Sponsor
- Oslo University Hospital
Spontaneous Coronary Artery Dissection
Spontaneous Coronary Artery Dissection National Swiss Registry
Spontaneous coronary artery dissection (SCAD), is an underdiagnosed pathology, affecting predominantly young women without traditional cardiovascular risk factors and is associated with major adverse outcomes including myocardial…
- Trial name
- SwissSCAD (NCT04457544)
- Where
- Switzerland
- Volunteers
- 1,000 people
- Sponsor
- Dr. Sophie Degrauwe
SCAD, ACS (Acute Coronary Syndrome)
Spontaneous Coronary Artery Dissection - AntipLatelet Therapy Intensity in Guided coNservative Management (SCAD-ALIGN) Trial
Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome in which blood flow to the heart muscle is reduced or interrupted.
- Trial name
- SCAD-ALIGN (NCT07683923)
- Testing
- Acetylsalicylic acid ASA, ASA plus Clopidogrel
- Where
- 5 sites in Canada, Germany and 3 more
- Volunteers
- 3,518 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Fibromuscular Dysplasia of Arteries, Fibromuscular Dysplasia
Survey on Physical Activity and Qualify of Life in Fibromuscular Dysplasia
Fibromuscular dysplasia (FMD) is a disease of the arteries that is not due to plaque build-up or inflammation. While some patients with FMD are health, some may experience heart attacks, strokes, aneurysms or blood vessel…
- Conditions
- Fibromuscular Dysplasia of Arteries, Fibromuscular Dysplasia, Spontaneous Coronary Artery Dissection
- Trial name
- NCT07529691
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Vanderbilt University Medical Center
Spontaneous Coronary Artery Dissection
Genetics of Spontaneous Coronary Artery Dissection (SCAD-INSPIRE Genetics)
Spontaneous coronary artery dissection (SCAD) is a rare cause of coronary ischemia and infarction where a tear in blood vessel wall either restricts the flow of blood or the blood becomes trapped in between the layers of the…
- Trial name
- SCAD-INSPIRE (NCT03876847)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Intermountain Health Care, Inc.
Spontaneous Coronary Artery Dissection
A Study of SCAD Using Stress Contrast Echocardiography
This study aims to fill knowledge gaps regarding microvascular perfusion and pressor response to stress among patients with history of spontaneous coronary artery dissection (SCAD) using stress contrast echocardiography.
- Trial name
- NCT07178509
- Testing
- Stress Echocardiography with Contrast
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Spontaneous Coronary Artery Dissection, Myocardial Infarction (MI)
Norwegian Danish Spontaneous Coronary Artery Dissection Exercise Study
The goal of this randomized clinical trial is to determine whether a supervised high-intensity interval training (HIIT) program can safely improve cardiorespiratory fitness and overall health in adults who have previously had…
- Conditions
- Spontaneous Coronary Artery Dissection, Myocardial Infarction (MI), High Intensity Interval Training
- Trial name
- NorDen-SCAD Ex (NCT07785765)
- Testing
- High intensity interval training (HIIT)
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
Spontaneous Coronary Artery Dissection, Healthy
A Study to Analyze the Role of Sympathetic Nervous System in Spontaneous Coronary Artery Dissection
The purpose of this research is to compare sympathetic function (flight or fight system) and arterial health including structure and mechanics of participants with history of spontaneous coronary artery dissection (SCAD) to age…
- Trial name
- NCT05699200
- Testing
- Arterial Tonometry, Echocardiogram, Carotid Ultrasounds
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Spontaneous Coronary Artery Dissection
SCAD : a Registry of Spontaneous Coronary Artery Dissection
Spontaneous coronary artery dissection (SCAD) is an increasingly recognised cause of non-atherosclerotic acute coronary syndromes (ACS), predominantly afflicting young women without conventional atherosclerotic risk factors.
- Trial name
- SCAD (NCT06601270)
- Testing
- There are no interventions as the study is purely observational.
- Where
- 73 sites in Argentina, Austria and 22 more
- Volunteers
- 1,500 people
- Sponsor
- European Society of Cardiology
Coronary Arterial Disease (CAD), ACS (Acute Coronary Syndrome)
Impact of CYP2C19 Genotype-guided Approach in Antiplatelet Therapy on Platelet Reactivity Index Among Coronary Artery Disease (CAD) Patients
The goal of this clinical trial is to learn if the pilot intervention of CYP2C19 genotype-guided antiplatelet therapy works to reduce the occurrence of cardiovascular events after Percutaneous Coronary Intervention (PCI) done in…
- Conditions
- Coronary Arterial Disease (CAD), ACS (Acute Coronary Syndrome), SCAD
- Trial name
- NCT06759272
- Testing
- CYP2C19 genotype-guided antiplatelet therapy
- Where
- Malaysia
- Volunteers
- 120 people
- Sponsor
- Nur Hafizah Annezah binti Utuh
Spontaneous Coronary Artery Dissection, SCAD
Canadian SCAD Study
Natural history multicenter, prospective, observational registry with 10-year follow-up
- Conditions
- Spontaneous Coronary Artery Dissection, SCAD, Fibromuscular Dysplasia
- Trial name
- NCT04906356
- Testing
- Genetic sub-study
- Where
- Canada
- Volunteers
- 3,000 people
- Sponsor
- Cardiology Research UBC
Spontaneous Coronary Artery Dissection, SCAD
The "Virtual" Multicenter Spontaneous Coronary Artery Dissection (SCAD) Registry
The primary goal of this project is to describe the clinical and physiologic characteristics of Spontaneous Coronary Artery Dissections (SCAD) in order to increase awareness, understanding, treatment and prevention of a…
- Trial name
- SCAD (NCT01429727)
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic