Spontaneous Coronary Artery DissectionNCT07497633
Spontaneous Coronary Artery Dissection (SCAD) Avatar Study
An observational study of Spontaneous Coronary Artery Dissection, run by Mayo Clinic at 1 site in United States.
Trial summary
The purpose of this study is to evaluate patient satisfaction, comfort, and trust in interacting with an avatar compared with speaking to a human clinician during a pre clinical visit. Read more about this study
- Who is it for?
- Ages 18 to 99 years
- Conditions the study is for
- Spontaneous Coronary Artery Dissection
- What is being tested?
- Video Avatar Interview, Voice-Only Avatar Interview and Human Interview
- How many people
- 150 participants
- Where
- 1 siteUnited States
- Study dates
- Dec 2026to May 2028
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 99 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Eligible SCAD patients will be identified once they have a confirmed Mayo Clinic SCAD Clinic appointment
Who may be able to join
- All patients scheduled for a SCAD appointment at Mayo Clinic
Who cannot join
- Not Applicable
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Spontaneous Coronary Artery Dissection (SCAD) Avatar Study (Pilot)
The purpose of this study is to evaluate patient satisfaction, comfort, and trust in interacting with an avatar compared with speaking to a human clinician during a pre clinical visit.
- Conditions
- Spontaneous Coronary Artery Dissection
- Being tested
- Video Avatar Interview, Voice-Only Avatar Interview, Human Interview
- Medical subject headings
- Coronary Artery Dissection, Spontaneous
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Video Avatar InterviewOther
Patients will undergo a pre-visit interview with a Video Avatar (LLM powered digital interviewer presented with on-screen video)
Voice-Only Avatar InterviewOther
Patients will undergo a pre-visit interview with a Voice-Only Avatar ( LLM-powered interviewer delivered without visuals)
Human InterviewOther
Patients will undergo a Human Interview conducted by trained Mayo personnel
| Study group | Role | What they receive |
|---|---|---|
| Video Avatar | Not described Receives: Other: Video Avatar Interview | |
| Voice-Only Avatar | Not described Receives: Other: Voice-Only Avatar Interview | |
| Human Interview | Not described Receives: Other: Human Interview |
What is being measured
The primary outcome is the main question the study is designed to answer.
Patient Satisfaction
Patient satisfaction with the AI avatar (Visual/Voice and Voice only) will be assessed using a structured questionnaire completed after the AI-conducted pre-interview. Responses will be measured on a numeric Likert scale (1-5), with higher scores indicating greater satisfaction and comfort with the AI avatar interaction.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Mar 2026
- Study startDec 2026 (estimated)
- Primary completionMay 2028 (estimated)
- Study completionMay 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Spontaneous Coronary Artery DissectionStudies of the same condition, open and under way.
- More trials run by Mayo ClinicThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 150 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Mayo Clinic
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Sharonne Hayes, Mayo Clinic
- Investigators
- Sharonne Hayes, M.D, Principal investigator, Mayo Clinic
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07497633
- Sponsor's protocol ID
- 25-014040
- Status last verified
- Sep 2026
- First submitted
- 23 Mar 2026
- Last updated
- 23 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 23 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Spontaneous Coronary Artery Dissection (SCAD) Avatar Study (Pilot)
- ClinicalTrials.gov ID
- NCT07497633
- Acronym / sponsor ID
- 25-014040
- Conditions
- Spontaneous Coronary Artery Dissection
- Study type
- Observational
- Recruitment status
- Enrolling by invitation
- Enrolment
- 150 participants (estimated)
- Lead sponsor
- Mayo ClinicUniversity, hospital or other
- Study start
- Dec 2026 (estimated)
- Primary completion
- May 2028 (estimated)
- Study completion
- May 2028 (estimated)
- First posted
- 27 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to evaluate patient satisfaction, comfort, and trust in interacting with an avatar compared with speaking to a human clinician during a pre clinical visit.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Video Avatar | – | Other: Video Avatar Interview |
| Voice-Only Avatar | – | Other: Voice-Only Avatar Interview |
| Human Interview | – | Other: Human Interview |
Who may qualify
- Ages
- 18 to 99 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Eligible SCAD patients will be identified once they have a confirmed Mayo Clinic SCAD Clinic appointment
Key inclusion criteria (1 listed)
- All patients scheduled for a SCAD appointment at Mayo Clinic
Key exclusion criteria (1 listed)
- Not Applicable
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Video Avatar InterviewPatients will undergo a pre-visit interview with a Video Avatar (LLM powered digital interviewer presented with on-screen video) | Other | Video Avatar |
| Voice-Only Avatar InterviewPatients will undergo a pre-visit interview with a Voice-Only Avatar ( LLM-powered interviewer delivered without visuals) | Other | Voice-Only Avatar |
| Human InterviewPatients will undergo a Human Interview conducted by trained Mayo personnel | Other | Human Interview |
Primary outcome
Patient Satisfaction
Time frame: Baseline
Patient satisfaction with the AI avatar (Visual/Voice and Voice only) will be assessed using a structured questionnaire completed after the AI-conducted pre-interview. Responses will be measured on a numeric Likert scale (1-5), with higher scores indicating greater satisfaction and comfort with the AI avatar interaction.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Sep 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Sharonne Hayes, M.D principal investigator
Mayo Clinic
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Spontaneous Coronary Artery Dissection, run by Mayo Clinic at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 23 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Patient Satisfaction (time frame: Baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Sep 2026.