Clinical trials: SCAD
SCAD, ACS (Acute Coronary Syndrome)
Spontaneous Coronary Artery Dissection - AntipLatelet Therapy Intensity in Guided coNservative Management (SCAD-ALIGN) Trial
Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome in which blood flow to the heart muscle is reduced or interrupted.
- Trial name
- SCAD-ALIGN (NCT07683923)
- Testing
- Acetylsalicylic acid ASA, ASA plus Clopidogrel
- Where
- 5 sites in Canada, Germany and 3 more
- Volunteers
- 3,518 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Spontaneous Coronary Artery Dissection, SCAD
Genetic Investigations in Spontaneous Coronary Artery Dissection (SCAD)
The purpose of the research is to identify mutations (defects in the genetic blueprint) that cause spontaneous coronary artery dissection (SCAD), in other words, spontaneous tears in blood vessels that supply the heart.
- Trial name
- NCT01427179
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Spontaneous Coronary Artery Dissection, SCAD
The "Virtual" Multicenter Spontaneous Coronary Artery Dissection (SCAD) Registry
The primary goal of this project is to describe the clinical and physiologic characteristics of Spontaneous Coronary Artery Dissections (SCAD) in order to increase awareness, understanding, treatment and prevention of a…
- Trial name
- SCAD (NCT01429727)
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
SCAD, Myocardial Infarction (MI)
Norwegian Spontaneous Coronary Artery Dissection Study
The Norwegian Spontaneous Coronary Artery Dissection Study (NOR-SCAD) is a national, multicenter prospective observational study conducted at major hospitals in Norway.
- Conditions
- SCAD, Myocardial Infarction (MI), Women
- Trial name
- NOR-SCAD (NCT07317323)
- Where
- 3 sites in Norway
- Volunteers
- 300 people
- Sponsor
- Oslo University Hospital
SCAD, AMI
Effects of Edoxaban on Platelet Aggregation
Rationale: The interaction between nonvitamin K oral anticoagulants (NOACs) and platelet aggregation is complex. The direct activated factor X inhibitors (factor Xa inhibitors) an NOAC antagonizes thrombin generation, one of most…
- Trial name
- Edoxaban (NCT05122455)
- Testing
- ASA, Clopidogrel, Edoxaban
- Where
- Brazil
- Volunteers
- 61 people
- Sponsor
- University of Sao Paulo
Coronary Arterial Disease (CAD), ACS (Acute Coronary Syndrome)
Impact of CYP2C19 Genotype-guided Approach in Antiplatelet Therapy on Platelet Reactivity Index Among Coronary Artery Disease (CAD) Patients
The goal of this clinical trial is to learn if the pilot intervention of CYP2C19 genotype-guided antiplatelet therapy works to reduce the occurrence of cardiovascular events after Percutaneous Coronary Intervention (PCI) done in…
- Conditions
- Coronary Arterial Disease (CAD), ACS (Acute Coronary Syndrome), SCAD
- Trial name
- NCT06759272
- Testing
- CYP2C19 genotype-guided antiplatelet therapy
- Where
- Malaysia
- Volunteers
- 120 people
- Sponsor
- Nur Hafizah Annezah binti Utuh
Coronary Artery Disease, Coronary Disease
Clinical Cohort Study - INTERCATH
Within a CAD patient cohort there is a wide variability of clinical manifestation and severity of coronary disease. Distinct determinants that would explain the variety of CAD phenotypes with differing prognosis are yet…
- Conditions
- Coronary Artery Disease, Coronary Disease, Coronary Syndrome, SCAD
- Trial name
- NCT04936438
- Where
- Germany
- Volunteers
- 5,000 people
- Sponsor
- University of Hamburg-Eppendorf
Cardiac Rehabilitation Program Following the Management of ACS in Patients Presenting With SCAD
Modalities And Safety Of Cardiac Rehabilitation In A Population Managed For Spontaneous Hematoma Or Coronary Disruption
Spontaneous Coronary Artery Dissection (SCAD) is a rare and often misdiagnosed cause of Acute Coronary Syndrome (ACS) affecting predominantly young women without cardiovascular risk factors.
- Trial name
- READAPT-DISCO (NCT05744947)
- Testing
- Data collection
- Where
- 29 sites in France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Bordeaux
Spontaneous Coronary Artery Dissection, SCAD
Canadian SCAD Study
Natural history multicenter, prospective, observational registry with 10-year follow-up
- Conditions
- Spontaneous Coronary Artery Dissection, SCAD, Fibromuscular Dysplasia
- Trial name
- NCT04906356
- Testing
- Genetic sub-study
- Where
- Canada
- Volunteers
- 3,000 people
- Sponsor
- Cardiology Research UBC
SCAD, Addison Disease
Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity
This case control study aims to determine whether spontaneous coronary artery dissection (SCAD) is associated with autoimmune diseases and to update the incidence of SCAD in a population-based cohort.
- Conditions
- SCAD, Addison Disease, Ankylosing Spondylitis, Antiphospholipid Antibody Syndrome
- Trial name
- NCT03941184
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Mayo Clinic