Clinical trials: Rhytides
Skin Aging, Facial Rhytides
AnteAGE Biosomes With Radiofrequency Microneedling for Facial Skin Rejuvenation
This prospective, randomized controlled study evaluated the efficacy and tolerability of AnteAGE Biosome Solution used in conjunction with facial radiofrequency microneedling.
- Conditions
- Skin Aging, Facial Rhytides, Skin Tone
- Trial name
- NCT07849556
- Testing
- AnteAGE Biosome Treatment Solution, Radiofrequency Microneedling, AnteAGE Homecare Regimen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cellese Inc.
Facial Aging, Skin Aging
Hyaluronic Acid Crosslinking Clinical Study
This prospective observational case series aims to evaluate the clinical efficacy, safety, and patient satisfaction associated with hyaluronic acid dermal fillers with different degrees of divinyl sulfone (DVS) crosslinking.
- Conditions
- Facial Aging, Skin Aging, Facial Volume Loss, Facial Rhytides
- Trial name
- HACS (NCT07744464)
- Testing
- Hyaluronic Acid Dermal Fillers
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Antony de Paula Barbosa
Wrinkles and Rhytides
Treatment of Aging Signs of the Skin With Bipolar Radiofrequency
This is a retrospective data collection from patients treated with the bipolar radiofrequency applicator (Coaxipolar) of the Accent devices.
- Trial name
- NCT07739212
- Where
- Kosovo
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Alma Mater Europaea College of Medical Sciences "Rezonanca"
Aging, Wrinkle
Restylane Refyne for Correction of Horizontal Neck Rhytides
Subjects with grades ranging from 1---3 on the Transverse Neck Line Scale, will be randomized to receive up to 1cc of Restylane Refyne on one side of their neck utilizing a cannula and up to 1cc of Restylane Refyne on the other…
- Conditions
- Aging, Wrinkle, Rhytides
- Trial name
- NCT04162496
- Testing
- Restylane Refyne
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Siperstein Dermatology
Facial Aging, Facial Wrinkles and Rhytides Reduction
Intradermal Microbotulinum Toxin for Sebum Reduction and Facial Pore Improvement
This study aims to evaluate the efficacy and safety of microdoses of botulinum toxin type A (microtoxin) for improving periocular skin quality and reducing fine wrinkles.
- Trial name
- MICROTOX-PORE (NCT07526870)
- Testing
- Botulinum Toxin Type A (Dysport®)
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Skin Laxity, Wrinkles
Safety and Efficacy Evaluation of High Intensity Focused Ultrasound Device in Eyebrow Lifting
The goal of this clinical trial is to assess the safety and efficacy of the high-intensity focused ultrasound (HIFU) device, ULTRAFORMER MPT (UF4-M400), developed by CLASSYS Inc., for eyebrow lifting.
- Conditions
- Skin Laxity, Wrinkles, Facial Wrinkles and Rhytides Reduction
- Trial name
- NCT06724510
- Testing
- HIFU treatment with ULTRAFOMER MPT
- Where
- 4 sites in China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- CLASSYS Inc.
Dermal Fillers, Cheek Augmentation
Evaluation of Performance and Safety of Injectable KIO017 Device Range for Facial Tissue Filling
The goal of this clinical trial is to primarily evaluate the performance of KIO017 in filling/volumizing after injection in different areas in healthy women or men, older than 18 years and seeking an improvement of her/his face…
- Conditions
- Dermal Fillers, Cheek Augmentation, Lip Augmentation, Perioral Rhytids
- Trial name
- LITCHEE (NCT06872359)
- Testing
- KIO017-1, KIO017-2, KIO017-3
- Where
- 3 sites in France, Poland
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Kiomed Pharma
Facial Wrinkles, Anti-Aging
Safety and Efficacy Evaluation of the Monopolar Radiofrequency Device for the Improvement of Facial Wrinkles
The goal of this clinical trial is to evaluate the safety and efficacy of the monopolar radiofrequency therapy device developed by CLASSYS Inc. for improving facial and periorbital wrinkles.
- Conditions
- Facial Wrinkles, Anti-Aging, Wrinkles and Rhytides, Wrinkles Such as Nasolabial Folds
- Trial name
- NCT06657365
- Testing
- Radiofrequency (RF) Treatment with Volnewmer, Radiofrequency (RF) Treatment with Thermage CPT
- Where
- China
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- CLASSYS Inc.
Parotid Gland Tumor, Facial and Neck Rhytides
Facial Nerve Monitoring During Parotid and Facial Surgery Using a Non-Invasive Patch
The goal of this study is to test if a non-invasive patch can safely monitor facial nerve activity in adults during parotid or facial surgery.
- Trial name
- NCT07523373
- Testing
- Non-invasive facial nerve monitoring patch
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Photodamaged Skin, Rhytids
2910 nm Erbium-Doped Fluoride Fiber Glass Laser for the Treatment of Advanced Perioral Lines and Wrinkles
The primary objective is to assess the efficacy, safety and satisfaction associated with the resurfacing treatment of perioral lines and wrinkles with the 2,910 nm mid-infrared Fiber Laser (UltraClear, Acclaro Medical) using both…
- Conditions
- Photodamaged Skin, Rhytids, Lines Skin, Wrinkles and Rhytides
- Trial name
- NCT07222397
- Testing
- Laser Resurfacing
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- FA Corporation
Facial Aging, Skin Rejuvenation
Performance and Safety of Semical Dermal Fillers in Facial Rejuvenation
The aim of the study is to verify safety and performance of Semical dermal fillers according to real-world data.
- Conditions
- Facial Aging, Skin Rejuvenation, Volume Defects in the Mid-face, Lip Augmentation and Correction of Perioral Rhytids
- Trial name
- SEMDERMA (NCT07160777)
- Testing
- cross-linked hyaluronic acid, Mesolifter
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Semikal Technology
Rhytides, Skin Texture Irregularities
Efficacy & Safety of hADM Skin Booster
The goal of this randomized, split-face, double-blinded clinical trial is to evaluate the efficacy and safety of Elravie Re2O (particulated human Acellular Dermal Matrix, phADM) as a skin booster compared with hyaluronic acid…
- Conditions
- Rhytides, Skin Texture Irregularities, Photoaged Facial Skin, Skin Lifting and Tightening
- Trial name
- NCT07155278
- Testing
- Elravie Re2O, Elravie Balance
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yonsei University
Wrinkles and Rhytides
Eye Cream 8-Week Efficacy Clinical Study
To investigate efficacy on test cream [Formula#899675 44A] on female subjects after 2-week wash-out and 8-week repeated application.
- Trial name
- NCT07079501
- Testing
- Test Eye Cream (Formula# 899675 44A)
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Forehead Rhytides
A Study Comparing the Safety, Efficacy, and Diffusion of Letibotulinum Toxin A Versus Other Botulinum Toxin Products in Adults With Moderate-to-Severe Forehead Wrinkles
The goal of this clinical trial is to learn if letibotulinum toxin A is effective and safe for treating moderate-to-severe horizontal forehead wrinkles in adults.
- Trial name
- NCT07072806
- Testing
- Letibotulinum toxin A, Prabotulinum toxin A, Onabotulinum toxin A
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yonsei University
Facial Wrinkles and Rhytides Reduction
Cream Short-term Efficacy Clinical Study
This study aimed to evaluate the short-term efficacy of a facial cream (Formula# 899675 44A) on improving various skin quality and wrinkle parameters after a single application.
- Trial name
- NCT07067086
- Testing
- Test Cream
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Facial Rhytides, Skin Folds
Study to Evaluate Subject Satisfaction With Facial Appearance and Impact of Combined Facial Treatment
The primary objective of this study is to quantify the psychological, social, and emotional impact of comprehensive aesthetic treatment with a portfolio of the Sponsor's products by measuring the change in subject's satisfaction…
- Conditions
- Facial Rhytides, Skin Folds, Loss of Volume and Skin Quality
- Trial name
- NCT04609020
- Testing
- JUVÉDERM, BOTOX, HArmonyCA Lidocaine
- Where
- 6 sites in Brazil
- Volunteers
- 64 people
- Sponsor
- Allergan
Rhytides, Wrinkle
Safety and Efficacy of SofWave Treatment to Lift the Upper Lip and Improve the Peri-Oral Rhytids
Open-label, non-randomized, prospective, multi-center, self-controlled
- Trial name
- NCT06104514
- Testing
- Sofwave
- Where
- 6 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sofwave Medical LTD
Wrinkle, Rhytides
Healing Study of Fractional Skin Resurfacing and Tissue Histopathology After Ellacor Treatment
The goal of this study is to observe the healing of skin after ellacor® treatment at different timepoints, depths and coring densities.
- Conditions
- Wrinkle, Rhytides, Histopathology
- Trial name
- NCT06502470
- Testing
- ellacor® Micro-Coring procedure
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Cytrellis Biosystems, Inc.
Histopathology, Wrinkle
Open Label Study Exploring Tissue Histopathology After Ellacor® Procedure in an Abdominoplasty Model.
The goal of this study to better understand how the ellacor® Micro-Coring™ procedure works using an abdominoplasty, or tummy tuck surgery, model.
- Conditions
- Histopathology, Wrinkle, Rhytides
- Trial name
- NCT06421207
- Testing
- ellacor® Micro-Coring procedure
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Cytrellis Biosystems, Inc.
Rhytides, Wrinkle
BCT-HA Kit for Dehydrated and Wrinkled Skin
This study will assess the efficacy of Cellular MatrixTM BCT-HA Kit treatment compared to placebo condition on revitalization and skin rejuvenation on the midface.
- Trial name
- NCT05514834
- Testing
- Cellular Matrix TM BCT-HA Kit (ref. BCT-HA-3), PRP Only
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Minnesota