Clinical trials: Retention, active
Substance Use Disorders, Alcohol Use Disorder
Impact of Federal and State Medications for Opioid Use Disorder (MOUD) Policy Changes During the Pandemic
"Gold-standard" medications for opioid use disorder (MOUD) treatment combines FDA-approved medications, primarily methadone and buprenorphine, with behavioral therapies to provide "whole-patient" treatment.
- Conditions
- Substance Use Disorders, Alcohol Use Disorder, Opioid Use Disorder
- Trial name
- IMPACT (NCT07232641)
- Where
- United States
- Volunteers
- 185,810 people
- Sponsor
- Boston University
Edentulous Alveolar Ridge In Mandible, Complete Edentulism
Compare the Difference in Occlusal Force Distribution and Denture Retention Using 2 Different Denture Base Materials in Implant Retained Overdenture
The global increase in the aging population has led to a rise in total edentulism, which remains a major public health concern. two-implant-retained mandibular overdentures have been regarded as the standard of care, offering…
- Conditions
- Edentulous Alveolar Ridge In Mandible, Complete Edentulism, Dental Implant, Attachments
- Trial name
- NCT07250503
- Testing
- Conventional acrylic resin denture, Flexible resin denture
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Hemorrhage, Obstetric, Uterine Abnormality
Evaluation of the Non-inferiority of Resorbable Gelatin Embolization Compared to Embolization Combined With Endometrial Aspiration for the Management of Hemorrhagic Uterine Vascular Abnormalities Following Premature Termination of Pregnancy
The goal of this clinical trial is to determine the best treatment for patients who experience vaginal bleeding following a premature termination of pregnancy.
- Conditions
- Hemorrhage, Obstetric, Uterine Abnormality, Uterine Artery Embolization, Vaginal Bleeding During Pregnancy
- Trial name
- NIEMBUT (NCT07206342)
- Testing
- embolization therapy, embolization followed by aspiration
- Where
- 4 sites in France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Grenoble
Urinary Retention
Post-operative Urinary Retention (POUR) Following Thoracic Surgery
Inability to urinate a common complication that happens to many patients after a surgery, especially in men over 60 years of age who undergo surgery on their chest.
- Trial name
- POUR (NCT03609580)
- Testing
- Tamsulosin - 1 week, Tamsulosin - 3 days
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Hackensack Meridian Health
Urinary Retention
Post Operative Urinary Retention (POUR) Following Thoracic Oncological Surgery
This is a feasibility study looking at whether the use of Tamsulosin could lower the high incidence of postoperative urinary retention (POUR) in older men who undergo an oncological thoracic surgical procedure for suspected or…
- Trial name
- NCT05657990
- Testing
- Tamsulosin
- Where
- 4 sites in United States
- Volunteers
- 46 people
- Sponsor
- Hackensack Meridian Health
Postoperative Urinary Retention (POUR)
Efficacy of Acupuncture for Postoperative Urinary Retention Following Radical Hysterectomy for Cervical Cancer
The goal of this clinical trial is to learn if acupuncture works to treat postoperative urinary retention in patients who have undergone radical hysterectomy for cervical cancer.
- Trial name
- APOUR (NCT07711977)
- Testing
- Acupuncture
- Volunteers
- 324 people
- Sponsor
- Obstetrics & Gynecology Hospital of Fudan University
Prosthetic Joint Infection, Debridement With Prosthesis Retention
Antibiotic-coated Braided Suture Study
The purpose of this study is to evaluate whether the use of antibiotic-coated (triclosan) braided sutures is non-inferior or potentially superior to standard monofilament sutures in patients with prosthetic joint infections…
- Conditions
- Prosthetic Joint Infection, Debridement With Prosthesis Retention, Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee
- Trial name
- NCT07322289
- Testing
- VICRYL™ Plus (Coated VICRYL™ Plus Antibacterial), Polydioxanone (PDS™ II ) Sterile Synthetic Absorbable Surgical Suture-Monofilament
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- University of Miami
Opioid Use Disorder, Digital Health Intervention
Pilot Testing of the emPath Platform to Improve Medication for Opioid Use Disorder (MOUD) Linkage and Retention Among Adults With Opioid Use Disorder in Durham, North Carolina
This pilot study will evaluate the emPath digital platform, a platform designed to improve access to and retention in low-barrier telemedicine for delivery of medication for opioid use disorder (MOUD) among adults with opioid use…
- Conditions
- Opioid Use Disorder, Digital Health Intervention, Telemedicine, Outreach Intervention
- Trial name
- NCT07810322
- Testing
- emPath Intervention
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Duke University
Opioid Use Disorder
Identifying Optimal Buprenorphine Dosing for Opioid Use Disorder Treatment and Prevention of Overdose
The investigators aim to test the effectiveness of a high maintenance daily dose of buprenorphine (24 mg) for improving outcomes among patients who used fentanyl compared to the standard daily dose (16 mg).
- Trial name
- Optimal Bup (NCT06316830)
- Testing
- Buprenorphine
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Rhode Island Hospital
Mucus Retention, Mechanical Ventilation Complication
Effects of Mechanical Insufflation-Exsufflation With Optimized Settings on Wet Mucus Volume During Invasive Ventilation
Retention of airway secretions is a frequent complication in critically ill patients requiring invasive mechanical ventilation (MV).This complication is often due to excessive secretion production and ineffective secretion…
- Trial name
- NCT06491017
- Testing
- MI-E Intervention protocol, Standard MI-E setting
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Tuberculosis (TB), Tuberculosis Infection, Latent
Screening With Portable X-rays for Rapid Recognition of TB
SPOT-TB (Screening with Portable X-rays for rapid recOgniTion of TB) is a prospective study evaluating a community-based tuberculosis (TB) screening strategy for migrant populations in New York City.
- Conditions
- Tuberculosis (TB), Tuberculosis Infection, Latent, HIV (Human Immunodeficiency Virus)
- Trial name
- SPOT-TB (NCT07737275)
- Testing
- Mobile chest radiography for tuberculosis screening
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Columbia University
Gambling Disorder, Gambling Problem
Contingency Management to Reinforce Attendance to Cognitive Behavioral Treatment for Gambling Disorder
The aim of this study is to conduct a trial to investigate the effectiveness of adding contingency management treatment (CM) to standard care cognitive behavioral therapy (CBT) for the treatment of gambling disorder to increase…
- Trial name
- NCT07016100
- Testing
- Contingency management, Cognitive behavioral therapy/ treatment as usual
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- East Tennessee State University
Fertility Issues, Emotional Stress
Frame Support Study
This is a randomized, controlled pilot study evaluating an intervention of non-significant risk. Potential subjects will be women who have completed an initial new patient consultation at one of the participating fertility…
- Trial name
- NCT07083700
- Testing
- Frame Access
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Inception Fertility Research Institute, LLC
Dental Sealant, Sealant Retention
COES: Curing Order Effects on Sealants
Background: Sealants are a great tool in the prevention of caries in the pediatric population. It has been shown that up to 71% of occlusal decay is preventable after a single sealant application in a fissure, and thus is the…
- Trial name
- COES (NCT06342258)
- Testing
- Ultradent Ultra Seal XT Plus
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Opioid Use Disorder
A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder
VA-BRAVE will determine whether a 28-day long-acting injectable sub-cutaneous formulation of buprenorphine at a target dose of 300 milligrams (mg) is superior in retaining Veterans in opioid treatment and in sustaining opioid…
- Trial name
- VA-BRAVE (NCT04375033)
- Testing
- Sublingual buprenorphine with naloxone, Injectable subcutaneous buprenorphine
- Where
- 25 sites in United States
- Volunteers
- 952 people
- Sponsor
- VA Office of Research and Development
HIV 1 Infection
Study on Retention in Care and on Clinical Chracteristics of HIV-infected Women Treated With Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIKWO).
Women are an underrepresented population in clinical studies on HIV and antiretroviral therapy. This study aims to help bridge this gap by providing real-world data on therapeutic management with B/F/TAF (Biktarvy) in an…
- Trial name
- BIKWO (NCT07859904)
- Testing
- Bictegravir (BIC) plus Emtricitabine (FTC) plus Tenofovir Alafenamide (TAF)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Ente Ospedaliero Ospedali Galliera
Orthodontic Retainers, Tooth Mobility
Comparison Physiological Tooth Mobility and Retention Success in Patients Using Different Retainers
The purpose of this prospective clinical study is to comparatively evaluate the long-term stability of teeth, physiological tooth mobility, and effects on periodontal tissues of three different fixed lingual retainer materials…
- Trial name
- NCT07801768
- Testing
- Mobility measurement with Periotest device, Digital intraoral impression
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Marmara University
Inflammatory Arthritis, Spondylarthropathies
Assessing Pain by the painDETECT Questionnaire (PDQ)
Prospective cohort study using drug survival rates to assess the predictive value of the PDQ when used to classify patients into a non-neuropathic pain phenotype group (score <13) or a neuropathic pain phenotype group (score ≥13)
- Conditions
- Inflammatory Arthritis, Spondylarthropathies, Rheumatoid Arthritis, Psoriatic Arthritis
- Trial name
- NCT06402396
- Testing
- bDMARDS
- Volunteers
- 7,056 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Skill Performance, Knowledge
Standard Two-Day Advanced Life Support (ALS) Versus One Day Recertification Course
this study aims to compare the effectiveness of a one-day versus two-day ALS recertification course in terms of knowledge retention, practical skills performance, participant satisfaction, and confidence.
- Trial name
- NCT07358741
- Where
- Egypt
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- National Hepatology & Tropical Medicine Research Institute
Cervical Cancer
Evaluation of the Cancer Tracking System (CATSystem)
Cervical cancer contributes to significant preventable mortality in Kenya where less than 20% of women are screened. The Cancer Tracking System (CATSystem) is a web-based, algorithm generated tool to promote guideline adherent…
- Trial name
- CATSystem (NCT06286462)
- Testing
- Cancer Tracking System (CATSystem)
- Where
- 10 sites in Kenya
- Volunteers
- 6,600 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center