Clinical trials: Remote Ischemic Conditioning
Moyamoya Disease, TIA
The Effect of RIC on TIA/Stroke in Children With Moyamoya Disease
Moyamoya disease is a common reason of transient ischemic attack (TIA) and stroke in children. Remote ischemic conditioning (RIC) has been shown to prevent recurrent stroke in intracranial arterial stenosis, but it is unclear…
- Conditions
- Moyamoya Disease, TIA, Children, Stroke
- Trial name
- RIC-PMD-1 (NCT03821181)
- Testing
- RIC group
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Capital Medical University
Ischemic Heart Disease
Effects of Remote Ischemic Conditioning on Myocardial Perfusion in Humans
Cardiovascular disease is the second leading cause of death in Denmark, and ischemic heart disease accounts for the bulk of it. The purpose of this study is to clarify whether a mechanical method of remote ischemic conditioning…
- Trial name
- CONDI-PET (NCT02230098)
- Testing
- Remote Ischemic Conditioning
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Diabetes Mellitus, Coronary Artery Bypass
Remote Ischemic Preconditioning in Type 2 Diabetic Patients Undergoing CABG
This randomized, double-blind, prospective clinical trial aims to investigate the effect of remote ischemic preconditioning (RIPC) on myocardial protection in patients with type 2 diabetes mellitus undergoing elective coronary…
- Conditions
- Diabetes Mellitus, Coronary Artery Bypass, Remote Ischaemic Conditioning
- Trial name
- NCT06977230
- Testing
- Remote Ischemic Preconditioning
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Muğla Sıtkı Koçman University
Remote, Ischemic Conditioning
Remote Ischemic Conditioning in Patients Undergoing Primary Percutaneous Coronary Intervention
This study aimed to detect the effects of remote ischemic conditioning on infarct size, global contractility, morbidity, mortality, and renal function in patients undergoing primary percutaneous coronary intervention.
- Conditions
- Remote, Ischemic Conditioning, Primary Percutaneous Coronary Intervention
- Trial name
- NCT07272408
- Testing
- Remote ischemic conditioning, Normal primary percutaneous coronary intervention
- Where
- Egypt
- Volunteers
- 2 people
- Sponsor
- Helwan University
Cerebral Small Vessel Diseases
Remote Ischemic Conditioning on Cerebral Small Vessel Disease
This trial is a randomized, controlled, single-center, double-blind trial. Cerebral small vessel disease (CSVD) patients will be recruited and randomized into RIC or control group.The protective effect of remote ischemic…
- Trial name
- RIC-SVD (NCT04816500)
- Testing
- Automatic ischemic conditioning treatment instrument, Regular treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
Retinal Ischemia, Diabetes Complications
Changes in the Diameter of Retinal Vessels After Remote Ischemic Conditioning in Patients With Type 1 Diabetes
Remote ischemic conditioning (RIC) is a therapeutic strategy for protecting organs or tissue against the detrimental effects of acute ischemia-reperfusion injury.
- Conditions
- Retinal Ischemia, Diabetes Complications, Ischemia, Diabetes Mellitus, Type 1
- Trial name
- NCT03906383
- Testing
- Remote Ischemic Conditioning
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- University of Aarhus
Stroke
Augmenting Cerebral Blood Flow in Acute Ischemic Stroke
The most common type of stroke is ischemic (lack of blood flow to the brain due to a clot blocking a blood vessel). Time is brain and an average of 1.9 million brain nerve cells per minute are destroyed in patients experiencing a…
- Trial name
- NCT06911385
- Testing
- Arm Remote Ischemic Conditioning plus Pneumatic Compression lower limb
- Volunteers
- 150 people
- Sponsor
- University of Alberta
Stroke, Acute
Exercise and RIC and TCD
The first week after a stroke is a particularly important time, as improving blood flow may limit secondary ischaemic damage to the brain and help reduce the overall burden neurological injury and future disability.
- Trial name
- NCT03968068
- Testing
- Exercise Procedure, Remote Ischaemic Conditioning
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Moyamoya Disease, Moyamoya Syndrome
Evaluating Antiplatelet and Physical Therapy for Slowing Progression in Mild Moyamoya Disease.
Moyamoya disease (MMD) is a chronic occlusive cerebrovascular disease characterized by progressive stenosis or occlusion at the terminal portion of the internal carotid artery, with formation of an abnormal vascular network at…
- Conditions
- Moyamoya Disease, Moyamoya Syndrome, Aspirin, Remote Ischemic Conditioning
- Trial name
- MOUNT-EASE (NCT07762547)
- Testing
- aspirin treatment, Remote Ischemic Conditioning
- Where
- China
- Volunteers
- 724 people
- Sponsor
- Beijing Tiantan Hospital
Cerebral Palsy
Ischemic Conditioning to Enhance Function (I-C-FUN) in Children With Cerebral Palsy
The purpose of this research study is to determine if remote limb ischemic conditioning (RLIC) can increase skeletal muscle power, enhance learning of motor (dynamic balance) task, and improve walking performance in children with…
- Trial name
- I-C-FUN (NCT04598711)
- Testing
- RLIC, Muscle Power training, Balance training
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- East Carolina University
ST-elevation Myocardial Infarction (STEMI)
Long-term Clinical Outcome in Patients Undergoing Remote Ischemic Conditioning Before Primary Percutaneous Coronary Intervention for ST-elevation Myocardial Infarction: a Follow-up Study
The aim of this prospective follow-up study is to investigate 5-year clinical outcome in patients with ST-elevation myocardial infarction undergoing remote ischemic conditioning before primary percutaneous coronary intervention.
- Trial name
- NCT01665365
- Testing
- Remote ischemic perconditioning
- Where
- Denmark
- Volunteers
- 251 people
- Sponsor
- University of Aarhus
Enterocolitis, Necrotizing
Remote Ischemic Conditioning in Necrotizing Enterocolitis
Necrotizing enterocolitis (NEC) affects up to 10% of very preterm infants. NEC mortality is high (30-50 %) and has remained unchanged over the last decades. New treatments are urgently needed.
- Trial name
- NCT03860701
- Testing
- Remote ischemic conditioning
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- The Hospital for Sick Children
Acute Stroke
Remote Ischemic Conditioning Paired With Endovascular Treatment for Acute Ischemic Stroke (REVISE-1)
Currently, early reperfusion is considered as the most effective therapy for the treatment of acute ischemic stroke (AIS). Over the past 20 years, intravenous tissue plasminogen activator (IV tPA) has been demonstrated to be the…
- Trial name
- NCT03210051
- Testing
- Remote ischemic conditioning, Endovascular treatment
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Capital Medical University
Acute Ischemic Stroke
Remote Ischemic Conditioning for Acute Moderate Ischemic Stroke Due to Large Artery Atherosclerosis
Large Artery Atherosclerosis is one of the most prevalent causes of stroke worldwide and is associated with a high risk of disability and recurrent strokes.
- Trial name
- RIC-LAA (NCT06775782)
- Testing
- Remote Ischemic Conditioning (RIC) treatment, Medical Management
- Where
- China
- Volunteers
- 1,150 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Refractory Angina Pectoris
Effect of Daily Remote Ischemic Conditioning on the Life Quality of Refractory Angina Pectoris Patients
The purpose is to test whether daily ischemic conditioning of the arms over 30 days could reduce the frequency and severity of angina pectoris and improve the life quality of refractory angina pectoris patients.
- Trial name
- D-RIC-RAP (NCT02499250)
- Testing
- remote ischemic conditioning (TDFT-12-A2), Optimal medical treatment
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Navy General Hospital, Beijing
Diabetic Foot Ulcer, Diabetic Angiopathies
Remote Ischemic Conditioning and Diabetic Foot Ulcers
Study type: Randomized, double blinded, interventional, single-site study. Two groups: Active receiving RIC therapy from the LifeCuff device and standard of care treatment without RIC.
- Trial name
- NCT04567563
- Testing
- Remote Ischemic conditioning (RIC)
- Volunteers
- 50 people
- Sponsor
- Des Moines University
Chronic Kidney Diseases
The Renal Protective Effects of Remote Ischemic Preconditioning in Patients With Chronic Kidney Disease
The incidence of Chronic kidney disease (CKD) is showing an upward trend, but the therapeutic effect of treatment is limited. Remote ischemic conditioning (RIC) has the potential to safeguard remote organs via the repeated…
- Trial name
- NCT06501222
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Yuanjun Yang
Unruptured Intracranial Aneurysm, Infarction Cerebral
Chronic Remote Ischemic Conditioning in Small Infarctions Associated with Stent-assisted Coiling of Unruptured Intracranial Aneurysms
1. Disease Description Stent-assisted coiling has become an effective treatment modality for intracranial aneurysms. With continuous advancements in periprocedural antiplatelet regimens, the incidence of symptomatic…
- Trial name
- CRISIS (NCT06826144)
- Testing
- remote ischemic conditioning
- Volunteers
- 84 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Central Sympathetic Nervous System Diseases
Role of Sympathetic Activation in Ischemia Reperfusion Injury
This study is designed to assess the effect of forearm ischemia-reperfusion injury on sympathetic nerve activity. To determine whether reduced sympathetic responsiveness is a contributor to the protective effects of remote…
- Trial name
- NCT04479813
- Testing
- Moxonidine 0.2 MG
- Where
- Australia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Royal Perth Hospital
Myocardial Infarction, Anterior Wall
COmprehensive Remote Ischemic Conditioning in Myocardial Infarction
The primary objective of the CORIC-MI trial is to evaluate whether comprehensive (per, post plus delayed) remote ischemic conditioning (CORIC) as an adjunctive therapy in patients with ST-elevation myocardial infarction (STEMI)…
- Trial name
- CORIC-MI (NCT03233919)
- Testing
- comprehensive remote ischaemic conditioning
- Where
- China
- Volunteers
- 200 people
- Sponsor
- China National Center for Cardiovascular Diseases