Clinical trials: Refractive Errors
Myopia
Sustained Effect of Red-light Therapy for Myopia Control: A 2-Year Post-Trial Follow-up Study
To evaluate the long-term efficacy and safety of red-light therapy for myopia control over 2 years, and the potential rebound effect after treatment cessation.
- Trial name
- NCT06232161
- Testing
- Red-light therapy device, Spectacles
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Myopia
Comparison of Next Generation Laser Techniques of Myopia Correction: iDesign vs. SMILE
The proposed study seeks to compare visual acuity, tomographic outcomes, biomechanical changes and inflammatory profile of normal eyes (matched for age, refraction and corneal thickness) undergoing iDesign and SMILE procedure.
- Trial name
- NCT03001401
- Testing
- iDesign, SMILE
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Narayana Nethralaya
Refractive Error
Clinical Evaluation of Two Daily Disposable Contact Lenses
The objective of this study is to compare the ease of removing two daily disposable soft contact lenses off the eye.
- Trial name
- NCT01875471
- Testing
- delefilcon A, narafilcon A
- Where
- 11 sites in United Kingdom
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Myopia Prevention With Reading Glasses
The last decades have seen a significant increase in myopia in children and young adults. Possible cause: increased near-work (school, computer, smartphone).
- Trial name
- SMART2 (NCT05030103)
- Testing
- Reading glasses, +2.0 diopters
- Where
- Liechtenstein
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Reis Augenklinik AG
Axial Length, Myopia
China Children Eye Study
The primary objective of this multi-center, observational study is to establish the reference ranges of axial length in Chinese children and adolescents.
- Conditions
- Axial Length, Myopia, Child Development
- Trial name
- CCES (NCT05770661)
- Where
- 2 sites in China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Astigmatism
Performance of Fanfilcon A Toric Lenses After at Least One Month Wearing Enfilcon A Toric Lenses
This is a prospective, multi-center, subject-masked, bilateral, daily wear, two-month dispensing study
- Trial name
- NCT02921412
- Testing
- fanfilcon A
- Where
- 4 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Presbyopia Condition
A Randomized, Active-Controlled, Double-Masked, Crossover Study to Evaluate the Clinical Performance of Deseyne (Vifilcon C) Daily Disposable Soft Contact Lens for Presbyopia Extended Depth of Focus (EDOF)
The goal of this clinical trial is to learn if the contact lens we are testing will work to extend the range of clear focus at distance to provide an increase in clear vision at closer ranges without the additional need for…
- Trial name
- EDOF (NCT06698731)
- Testing
- Test lens, Control lens
- Where
- 3 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Bruno Vision Care
Myopia
Performance of DAILIES TOTAL1 Daily Disposable Contact Lenses in Habitual Soft Lens Wearers Who Report Substantial Digital Device Use
The purpose of this study is to evaluate the performance of DAILIES TOTAL1 daily disposable contact lenses with regards to subjective symptoms (comfort, dryness, vision) in lens wearers who use identify themselves as substantial…
- Trial name
- FOX (NCT06308666)
- Testing
- Delefilcon A contact lenses
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Full Spectrum
A Self-controlled Study of the Effect of Partial Spectral Absence of Visible Light on the Pupil
Previous studies have shown that the spectrum of light influences myopia. LED lights with a partially absent light spectrum increase the risk of myopia progression compared to LEDs with a full spectrum, potentially mediated by…
- Trial name
- NCT06501131
- Testing
- full-spectrum light exposure, specific spectrum absence light exposure
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataract, Nuclear Sclerosis
Evaluating the Need for the Pseudophakic Intraoperative Abberrometry in Toric IOL Implantation
To determine clinically significant difference in results obtained from cataract surgery using IA. One eye will receive aphakic measurements only and the fellow eye will receive aphakic and then pseudophakic measurements when…
- Conditions
- Cataract, Nuclear Sclerosis, Cortical Cataract, Posterior Subcapsular Cataract
- Trial name
- NCT03819842
- Testing
- Pseudophakic Measurement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alterman, Modi, & Wolter Ophthalmic Physicians & Surgeons
Presbyopia
1-Week Dispensing Evaluation of Kalifilcon A Daily Disposable Multifocal Compared to Ultra for Presbyopia
Experienced soft contact lens wearing subjects will be enrolled in this 1-week, confirmatory, randomized, bilateral, 2-way crossover, double masked (subject and investigator), repeated measures, dispensing study.
- Trial name
- NCT05325931
- Testing
- kalifilcon A Daily Disposable Multifocal, samfilcon A for Presbyopia
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Hyperopia
Comparing Low-cost Handheld Autorefractors - a Practical Approach to Measuring Refraction in Low Resource Settings
Study compares four portable vision measurement and eye-imaging technologies in terms of accuracy and time and ease of use with older adult (ages 40-100) participants in a developing-country setting (India).
- Trial name
- NCT03456245
- Testing
- Vision device validation
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Myopia
Visual Performance of Center Distance Daily Disposable Multifocal Lenses
The purpose of this study is to compare visual performance (high and low contrast acuity, reading acuity, contrast sensitivity, stereoacuity, accommodative response, eye hand coordination, far near vision, and dynamic vision)…
- Trial name
- ViPCD3 (NCT06475053)
- Testing
- NaturalVue Enhanced Multifocal 1 Day contact lens, MiSight 1 Day contact lens
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Visioneering Technologies, Inc
Myopia, Refractive Errors
VisuMax Femtosecond Laser Small Incision Lenticule Extraction for the Correction of High Myopia
The purpose of this study is to validate the safety and effectiveness of treating myopia (short-sightedness) higher than -10D using small incision lenticule extraction (SMILE) with the VisuMax femtosecond laser.
- Trial name
- NCT02528123
- Testing
- Small incision lenticule extraction, Tobramycin and dexamethasone, Ofloxacin
- Where
- United Kingdom
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- London Vision Clinic
Myopia
Evaluation of The Clinical Acceptance of Soft Contact Lenses for Myopia Control
The main objective of the study was to evaluate the clinical acceptance of soft contact lenses for Myopia control.
- Trial name
- NCT04709237
- Testing
- omafilcon A control lens, omafilcon A test lens 1, omafilcon A test lens 2
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Moderate to High Myopia
The purpose of this study is to determine whether the MEL 80 Excimer Laser is effective in the treatment of moderate to high myopia (nearsightedness), when used as part of the Laser In Situ Keratomileusis (LASIK) procedure.
- Trial name
- NCT00762541
- Testing
- MEL 80 Treatment of High Myopia
- Where
- 5 sites in United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Ametropia
Clinical Evaluation of HPT Treated Rigid Contact Lenses Made From Hexafocon A
This will be an up to six months, subject-masked, contralateral, parallel-group, randomised, daily wear study. All subjects will wear the Test lens in one eye and the Control lens in the other eye.
- Trial name
- NCT04525170
- Testing
- HPT treatment, untreated
- Where
- 2 sites in Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Contamac Ltd
Myopia, Progressive
Clinical Study of Light Therapy to Control Myopia Progression in Children
Low-lever red light therapy (LLLT) has been used to control myopia progression in China for a few years besides amblyopia therapy for a few decades.
- Trial name
- NCT05761379
- Testing
- Photobiomodualtion Therapy, Single vision spectacles for correction myopia
- Where
- China
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Presbyopia
Clinical Outcome of Extended-depth-of-focus Trifocal Intraocualr Lens (Triumf) Implantation
Clinical outcome of extended-depth-of-focus trifocal intraocualr lens (Triumf) implantation
- Trial name
- NCT04392024
- Testing
- Triumf
- Where
- South Korea
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Astigmatism
Evaluating and Improving Functional Driving Vision of Patients With Astigmatism
Small amounts of astigmatism are often uncorrected in contact lens wearers. The effect with respect to driving is unknown, but it could threaten safe operation of a motor vehicle, especially under conditions such as nighttime…
- Trial name
- NCT02624791
- Testing
- 1-DAY ACUVUE® MOIST contact lenses, 1-DAY ACUVUE® MOIST for ASTIGMATISM contact lenses, No contact lenses
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Virginia