Clinical trials: Rectal Prolapse
Rectocele; Female, Rectocele and Incomplete Uterine Prolapse
3D vs 2D-laparoscopy for Rectocele and Rectal Prolapse Correction: a Prospective, Randomized, Single Center Study
The aim is to compare proximate and remote results of 3D and conventional 2D laparoscopic interventions in terms of efficacy and safety in treatment of symptomatic rectocele and rectal prolapse.
- Conditions
- Rectocele; Female, Rectocele and Incomplete Uterine Prolapse, Rectocele and Complete Uterovaginal Prolapse, Rectal Prolapse
- Trial name
- LARC (NCT04817150)
- Testing
- Laparoscopic ventral mesh rectopexy
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexander Khitaryan
Rectal Prolapse
Recurrence of Dyschezia in Rectal Prolapse, Rectocele and Elytrocele
Prolapse of the rectum is a pathology that preferentially affects older women with a significant impact on quality of life. A very large number of therapeutic approaches can be proposed (functional treatment, surgical techniques…
- Trial name
- PEXITY (NCT04627610)
- Testing
- Rectal prolapse, rectocele and elytrocele
- Where
- France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Grenoble
Hemorrhoid, Hemorrhoids
Endoscopic Injection Sclerotherapy Versus Endoscopic Band Ligation for Grade I-III Internal Hemorrhoids
This study is a prospective, multicentre, and randomized-controlled clinical study.The researchers wanted to explore the optimal treatment regimen for soft hemorrhoid within I-Ⅲ degrees by evaluating and comparing the…
- Conditions
- Hemorrhoid, Hemorrhoids, Hemorrhoids Internal, Hemorrhoid Prolapse
- Trial name
- NCT05089500
- Testing
- Endoscopic injection sclerotherapy, Endoscopic Band Ligation
- Where
- 2 sites in China
- Volunteers
- 984 people, healthy volunteers welcome
- Sponsor
- Renmin Hospital of Wuhan University
Hemorrhoids Prolapse
Doppler-guided or Non Doppler-guided Arterial Ligation and Mucopexy for Third Degree Hemorrhoids: That is the Question
Hemorrhoidal disease is one of the most common proctological disease affecting the general population from the mid-teens onward with considerable implications for the National Health Service (NHS) both from an economic point of…
- Trial name
- HAMLeT (NCT03729414)
- Testing
- mucopexy with Doppler artery ligation, mucopexy without Doppler artery ligation
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Societa Italiana di Chirurgia ColoRettale
Posterior Laparoscopic, Lateral Laparoscopic
Posterior Versus Lateral Laparoscopic Mesh Rectopexy for the Management of Complete Rectal Prolapse
Aim of the study is to evaluate the outcomes of two different methods of mesh placement during laparoscopic rectopexy for the management of complete rectal prolapse lateral versus posterior mesh rectopexy
- Conditions
- Posterior Laparoscopic, Lateral Laparoscopic, Rectopexy, Complete Rectal Prolapse
- Trial name
- NCT06559085
- Testing
- Laproscopic posterior mesh rectopexy (Wells or LPMR), Laparoscopic lateral mesh rectopexy (Orr-Loygue)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Rectal Prolapse, Surgery
The Nordic Rectal Prolapse Study
The goal of this observational study is to gather data about surgical procedures for rectal prolapse in adult human subjects. The main question it aims to answer is: Which procedure is best for treating external rectal prolapse?…
- Conditions
- Rectal Prolapse, Surgery, Recurrence, Quality of Life
- Trial name
- NORDIC (NCT05569980)
- Where
- Denmark
- Volunteers
- 430 people
- Sponsor
- Aarhus University Hospital
Rectal Prolapse
Swedish Rectal Prolapse Trial
Rectal prolapse is a medical condition where rectum is protruding through the anal opening. The treatment is by surgery that can be performed with an anterior approach through the abdomen or a posterior perineal approach.
- Trial name
- NCT04893642
- Testing
- Suture rectopexy, resection rectopexy, Delorme's operation
- Where
- 12 sites in Sweden
- Volunteers
- 134 people
- Sponsor
- Danderyd Hospital
Vaginal Vault Prolapse, Uterine Prolapse
Laparoscopic Pectopexy and Laparoscopic Colporrhaphies in Pelvic Organ Prolapse Treatment
This prospective cohort study investigates the surgical outcomes of laparoscopic pectopexy and laparoscopic colporraphy performed at the Wellbeing Services County of South Ostrobothnia.
- Conditions
- Vaginal Vault Prolapse, Uterine Prolapse, Cystocele, Midline, Rectocele; Female
- Trial name
- NCT06902909
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- Tampere University Hospital
Rectal Prolapse, Fecal Incontinence
Clinical Outcomes of Rectopexy for Rectal Prolapse
This study evaluates the clinical outcomes of patients who underwent rectopexy for rectal prolapse, ODS or FI. Rectopexy is a surgical procedure used to restore and fix the rectum in its normal position.
- Conditions
- Rectal Prolapse, Fecal Incontinence, Rectopexy, Obstructive Defecation Syndrome
- Trial name
- NCT07848308
- Testing
- anterior mesh rectopexy
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- Lukas Marti
Pelvic Floor Disorders
Correlation of Anal Acoustic Reflectometry Parameters With Degree of Rectal Intussusception and Prolapse
Anal Acoustic Reflectometry (AAR) is a reliable and reproducible technique that has been studied in our department over the last 6 years.
- Trial name
- NCT02774798
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- Manchester University NHS Foundation Trust
Rectal Prolapse
Safety and Performance Evaluation of a Biological Matrix Used for Rectal Prolapse Repair by Ventral Rectopexy
The general objective of the study is to confirm the medium/long-term safety and clinical performance of the CELLIS Rectopexy membrane used in rectal prolapse repair by ventral rectopexy and to identify emerging risks in…
- Trial name
- NCT04130555
- Testing
- CELLIS Rectopexy (Porcine Acellular Dermal Matrix, PADM)
- Where
- 3 sites in France
- Volunteers
- 55 people
- Sponsor
- Meccellis Biotech
Sexuality, Pelvic Organ Prolapse
Psychometric Validation of a French Version of the PISQ-R and a New Questionnaire About Sexuality
The primary objective of this study is the psychometric validation of two questionnaires (PISQ-R and a new questionnaire on sexuality) as compared to a non specific questionnaire on female sexual function (FSFI).
- Conditions
- Sexuality, Pelvic Organ Prolapse, Urinary Incontinence, Fecal Incontinence
- Trial name
- NCT01632839
- Where
- 14 sites in France
- Volunteers
- 298 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Rectal Prolapse
LVMR Versus PSR for External FTRPin Elderly Patients
In frail patients with external full-thickness rectal prolapse (FTRP), the exact postoperative recurrence and functional result outcomes difference between Laparoscopic ventral mesh rectopexy (LVMR) and perineal stapler resection…
- Trial name
- NCT05915936
- Testing
- LVMR, PSR
- Volunteers
- 330 people
- Sponsor
- Zagazig University
Rectal Prolapse
Frailty Increase Rectal Prolapse Recurrence
evaluate recurrent RP in relation to frailty
- Trial name
- NCT07230275
- Testing
- LVMR for RP, PSR for RP
- Volunteers
- 342 people
- Sponsor
- Zagazig University
Uterine Prolapse, Urinary Incontinence
The Immune Reactivity of Biofilms in Vaginal Mesh Erosion.
Aging, birth trauma and extensive pelvic surgery are the causes known to cause advanced pelvic organ prolaspe, fecal as well as urinary incontinence.
- Conditions
- Uterine Prolapse, Urinary Incontinence, Fecal Incontinence
- Trial name
- NCT00564044
- Testing
- excision of the protruding mesh and its surrounding vaginal tissue
- Where
- Taiwan
- Volunteers
- 82 people
- Sponsor
- Chang Gung Memorial Hospital
Rectal Cancer, Colon Cancer
Perfusion Assessment in Laparoscopic Left Anterior Resection
The purpose of this study is to demonstrate that NIR fluorescence angiography using the PINPOINT Endoscopic Fluorescence Imaging System ("PINPOINT System" or "PINPOINT") can assess viability of colon tissue during laparoscopic…
- Conditions
- Rectal Cancer, Colon Cancer, Crohn's Disease, Polyp
- Trial name
- PILLAR II (NCT01560377)
- Testing
- PINPOINT Endoscopic Fluorescence Imaging System
- Where
- 11 sites in United States
- Volunteers
- 147 people
- Sponsor
- Novadaq Technologies ULC, now a part of Stryker
Vaginal Vault Prolapse, Enterocele
Sacrocolpopexy Versus Vaginal Mesh Procedure for Pelvic Prolapse
Pelvic prolapse is one of the most frequent pathology in Gynecology. Recurrency of the prolapse after primary surgery is relatively high, 15-30%.
- Conditions
- Vaginal Vault Prolapse, Enterocele, Uterine Prolapse, Cystocele
- Trial name
- NCT01097200
- Testing
- Elevate mesh, Sacrocolpopexy
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Francisco Carmona
Rectal Prolapse, Fecal Incontinence
Recurrence and Bowel Function After Laparoscopic Vaginorectopexy, a Modified Anterior Rectopexy
Several pelvic prolapses can render defecation difficulties and they are often treated with different surgical techniques. This study will evaluate a novel variation of a laparoscopic technique used to treat rectal prolapse that…
- Conditions
- Rectal Prolapse, Fecal Incontinence, Defecation Disorder, Enterocele
- Trial name
- NCT06330857
- Testing
- Laparoscopic vaginorectopexy
- Volunteers
- 25 people
- Sponsor
- Sahlgrenska University Hospital
Rectal Prolapse, Procidentia
An International Double Cohort Study to Compare Laparoscopic Ventral Rectopexy With Laparoscopic Resection Rectopexy
Background: Rectal prolapse (RP) is the descent of the upper rectum and is a common problem in the western world. Surgery is the only definite treatment and is preferably performed minimally invasive.
- Trial name
- LaProS (NCT01595412)
- Testing
- Laparoscopic Resection Rectopexy, Laparoscopic Ventral Rectopexy
- Where
- 6 sites in United States
- Volunteers
- 2 people
- Sponsor
- The Cleveland Clinic
Pelvic Organ Prolapse
Evaluation of the Avaulta Procedure for the Correction of Pelvic Organ Prolapse - Results at 1 Year
This study is a 1 year review of all patients who had surgery to correct pelvic organ prolapse (i.e. cystocele, rectocele, enterocele) using the Avaulta synthetic mesh kit.
- Trial name
- NCT00774215
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Atlantic Health System