Clinical trials: Randomized Clinical Trial
HIV
mHealth Physical Activity Trial for Older HIV-infected Adults (mFIT)
This pilot study will examine the effect of a mobile health text messaging platform linked to a digital physical activity tracker on physical activity among persons living with HIV and frailty.
- Trial name
- NCT03708640
- Testing
- Digital Activity Tracker, Smart Text Messaging, Physical Activity Counseling
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Parenting, Child Abuse
Parents Make the Difference II: Trial of a Parenting Intervention
Multisite randomized trial of a parenting intervention in Liberia for caregivers of young children. Two main objectives of the "Parents Make the Difference" program are to teach parents (a) skills for decreasing harsh punishments…
- Trial name
- PMD2 (NCT02852291)
- Testing
- Parents Make the Difference, Parents Make the Difference Plus
- Where
- Liberia
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Duke University
Apico Marginal Defects
Efficacy of Guided Tissue Regeneration in the Healing of Periapical Defects With Periodontal Communication Using CBCT
Healing of the Apicomarginal defects will be checked by comparing 2 groups . In first group amniotic membrane will be applied over the defect before flap closure during surgery and in second group no GTR material will be applied.
- Trial name
- NCT03905590
- Testing
- Periapical surgery with amniotic membrane, periapical surgery without amniotic membrane
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Contraceptive Usage, Contraception Behavior
Effectiveness Testing of a Videogame Intervention (No Baby No) to Decrease Contraception Non-use Among Adolescents.
The purpose of this study is to evaluate the effectiveness of a videogame compared to an attention/time control at reducing contraceptive non-use among adolescents.
- Trial name
- NCT06990724
- Testing
- Videogame Intervention, Commercial game control
- Where
- 7 sites in United States
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Smoking &Amp; Tobacco Cessation
An Innovative Conversational Agent (Quitbot) for Smoking Cessation
This phase III trial compares two remote digital smoking cessation programs to see how well they work for quitting smoking.
- Trial name
- NCT04308759
- Testing
- Experimental Smoking Cessation Program, Control Smoking Cessation Program
- Where
- United States
- Volunteers
- 1,647 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
White Spot Lesion
The Effect of ICON Treatment on WPL With Patients After Fixed Orthodontic Appliances
The aim of this study is to determine the effect of ICON on White spot lesions compared to CPP-ACPF plus.
- Trial name
- NCT03391180
- Testing
- ICON Remineralization, CPP-ACPF
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Varying Heights of Power Arm During en Masse Retraction
Effects on Maxillary Anterior Dentition Following En Masse Retraction Using Mini-implants and Various Heights of Anterior Power Arm.
The controlled three dimensional movement of anterior dentition during orthodontic treatment is a desire of every orthodontist. Maxillary en masse retraction with mini implants has been reported to provide absolute anchorage thus…
- Trial name
- NCT04184427
- Testing
- Anterior Power Arm
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Functional Disorder
Patient Education and Duloxetine, Alone and in Combination, for Patients With Multisystem Functional Somatic Disorder
The goal of this clinical trial is to test if patient education or duloxetine can be used to treat multisystem functional somatic disorder (FSD).
- Trial name
- EDULOX (NCT06232473)
- Testing
- Patient Education, Duloxetine, Enhanced usual care
- Where
- Denmark
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Hand Hygiene, Health Education
Effect of Virtual Reality-Based Handwashing Education on Knowledge, Skills, and Emotional Indicators in Preschool Children
A randomized controlled trial designed to evaluate the effects of virtual reality-based handwashing education on handwashing knowledge, skills, and emotional indicators in preschool children aged 5-6 years.
- Conditions
- Hand Hygiene, Health Education, Infection Prevention
- Trial name
- VR-HAND (NCT07518082)
- Testing
- Virtual Reality-Based Handwashing Education, Traditional Handwashing Education
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Istanbul Arel University
Edentulous; Alveolar Process, Atrophy
Reliability of All on 4 Using 2 Zygomatic and 2 Conventional Implants vs All on 4 Implants for Rehabilitation of Maxilla
Oral rehabilitation by dental implants in the severely atrophic maxilla often represents a challenge. To overcome this difficulty, bone augmentation procedures such as sinus augmentation, guided bone regeneration (GBR), or…
- Trial name
- NCT05108324
- Testing
- zygomatic implant, conventional implant
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Zinc Deficiency
Clinical Trial to Determine the Bioavailability of Three Different Zinc Preparations
The main objective of this clinical is to get information on pharmacokinetics of zinc-enriched yeast.The bioavailability of the yeast enriched with zinc will be compared to two selected zinc salts used in food supplements that…
- Trial name
- NCT02292303
- Testing
- zinc-enriched yeast, Zinc references
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Lesaffre International
Healthy Young Men
Aronia Berry Consumption on Vascular Function
There is an increasing interest in the effects of various food derived polyphenols on vascular function. Arguably the most well-established vascular benefits are attributed to flavanols from cocoa beans and this has been…
- Trial name
- NCT03041961
- Testing
- Aronia full spectrum, Aronia extract
- Where
- United Kingdom
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- King's College London
Stigmatization, Depression
Impact of Video Presentations on Medical Students' Attitudes Toward Mental Illness
This is a randomized controlled trial examining the impact of videos on medical students' implicit and explicit attitudes and knowledge related to mental illness in Nepal.
- Conditions
- Stigmatization, Depression, Psychosis
- Trial name
- NCT03231761
- Testing
- Service user testimonial videos, mhGAP didactic video
- Where
- 2 sites in Nepal
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- George Washington University
Healty Volunteers
Acute Effects of Thoracolumbar Fascia Myofascial Release on Cortical Activity
This study will examine the immediate (acute) effects of a single myofascial release technique applied to the thoracolumbar fascia on brain activity in healthy young adults aged 18-25.
- Trial name
- MFR-EEG (NCT07728617)
- Testing
- Thoracolumbar Fascia Myofascial Release (Pilat MIF Crossed-Hands Technique)
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Hitit University
Mental Illness
Multimodal Psychotherapy Training for Chinese Medical Students
Providing evidence-based, well-designed psychotherapy teaching to train them to get a basic understanding of psychotherapy and to gain required skills for clinical practice would be fundamental to medical students, residency.
- Trial name
- NCT06258460
- Testing
- psychotherapy training program intervention, the wail-list control intervention
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Diarrhea, Cholera
Randomized Controlled Trial of Killed Oral Cholera Vaccine in Kolkata
The primary purpose of this study is to estimate the efficacy of a two-dose regimen of the oral killed bivalent cholera vaccine when administered to individual residing in a cholera-endemic area in India.
- Conditions
- Diarrhea, Cholera, Vibrio Infections
- Trial name
- NCT00289224
- Testing
- bivalent killed whole cell oral cholera vaccine
- Where
- India
- Volunteers
- 69,329 people, healthy volunteers welcome
- Sponsor
- International Vaccine Institute
Phenylketonuria
Effect of L-carnitine Supplementation on Phenylalanine and Brain-derived Neurotrophic Factor Levels in Infants and Children With Phenylketonuria
Effect of L-carnitine supplementation on phenylalanine and brain-derived neurotrophic factor levels in infants and children with phenylketonuria L-carnitine is mainly obtained from foods such as red meat and milk that are limited…
- Trial name
- NCT06901323
- Testing
- L-carnitine
- Where
- Egypt
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Simvastatin, Photodynamic Therapy
Treatment of Intrabony Defects With Simvastatin and Antimicrobial Photodynamic Therapy
Antimicrobial photodynamic therapy (aPDT) is characterized by the association of photosensitizing agents, promoting the generation of reactive oxygen species like free radicals and singlet oxygen, which are cytotoxic to certain…
- Conditions
- Simvastatin, Photodynamic Therapy, Periodontal Diseases
- Trial name
- NCT05031923
- Testing
- SMV and antimicrobial photodynamic therapy, SMV application
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Thoracic Surgical Procedures
Erector Spinae Plane vs. Paravertebral Nerve Block for Thoracic Surgery
Continuous paravertebral analgesia and erector spinae plane blockade (ESP) are accepted techniques at University of Pittsburgh Medical Center (UPMC) for the management of thoracic pain following surgery and trauma.
- Trial name
- NCT03758261
- Testing
- Paravertebral nerve block, Erector Spinae nerve block
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Charles Luke
Patients Satisfaction
Patient Satisfaction, Peri-implant Parameters and Crestal Bone Evaluation of PEEK (Polyetheretherketone) Abutments Versus Zirconium Abutments Restored With PEEK Based Superstructure
The aim of the study is to evaluate the patients' satisfaction, peri-implant parameters (bleeding on probing, probing depth and plaque index) and crestal bone resorption of implants restored with PEEK abutments restored with PEEK…
- Trial name
- NCT03714074
- Testing
- PEEK implant abutment, Zirconia abutment
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
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