Clinical trials: RHINOPLASTY, active
Pain, Postoperative
Screen Addiction and Postoperative Pain
Excessive or problematic smartphone use has become increasingly common and has been associated with various psychological and physical health consequences, including anxiety, depressive symptoms, reduced sleep quality…
- Trial name
- NCT07242872
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Septal Extension Graft in Rhinoplasty, Primary Rhinoplasty
Unilateral Septal Extension Graft and Bilateral Septal Extension Graft in Droopy Tip and Its Effect on Tip Deviation
This study aims to compare between the unilateral and bilateral septal extension graft and evaluate the effect of each of them on tip deviation.
- Conditions
- Septal Extension Graft in Rhinoplasty, Primary Rhinoplasty, Nasal Projection
- Trial name
- NCT07446426
- Testing
- Unilateral septal extension graft, Bilateral septal extension graft
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Tanta University
Effect of Postoperative Topical St. John's Wort Oil (Hypericum Perforatum) on Periorbital Edema and Ecchymosis Following Rhinoplasty
THE EFFECT OF ST. JOHN'S WORT OİL APPLİCATİON ON PERIORBITAL EDEMA AND ECCHYMOSİS AFTER RHİNOPLASTY
Rhinoplasty is one of the most frequently performed procedures in aesthetic and reconstructive surgery, with steadily increasing demand worldwide.
- Trial name
- NCT07448051
- Testing
- Topical St. John's Wort oil application
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Inonu University
Pain, Postoperative
Liposomal Bupivacaine vs Standard Bupivacaine for Post-Rhinoplasty Analgesia
The purpose of this study is to find out which pain medication is more effective in reducing pain after nose surgery (rhinoplasty).
- Trial name
- NCT07689162
- Testing
- Standard Bupivacaine, Liposomal Bupivacaine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Washington University School of Medicine
Rhinoplasty Techniques
Hybrid Osteoplasty Versus Osteotomy in Rhinoplasty
This study is designed to compare two common techniques for reducing the nasal hump during rhinoplasty: the traditional method using osteotomes and rasps, and a newer technique called hybrid osteoplasty that uses a surgical…
- Trial name
- NCT07142525
- Testing
- Hybrid Osteoplasty, Traditional Osteotomy and Rasping
- Where
- Iraq
- Volunteers
- 200 people
- Sponsor
- University of Sulaimani
Pain, Postoperative, Opioid Use
A Prospective Randomized Double Blind Trial to Assess the Effect of a Single Preoperative Dose of Gabapentin on Postoperative Opioid Consumption in Patients Undergoing Rhinoplasty
Adding a single preoperative dose of gabapentin to the standard pain regimen will reduce postoperative opioid consumption within the first 72 hours in patients undergoing rhinoplasty.
- Trial name
- NCT03498261
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Septal Extension Graft in Rhinoplasty
Outcomes Assessment of Septal Extension Graft Versus Columellar Strut Graft in Rhinoplasty.
Nose is an important aesthetic landmark with its length, width, shape, and position in the middle of the face. Rhinoplasty is now one of the most common rhinological procedures with both functional and aesthetic aspects.
- Trial name
- NCT06958575
- Testing
- Septal extension graft, Columellar strut
- Volunteers
- 60 people
- Sponsor
- Assiut University
Intraoperative, Ketamine
Intraoperative Combination of Ketamine and Magnesium Sulfate Infusions on Postoperative Analgesia in Open Rhinoplasty
The study aims to evaluate the effectiveness of intraoperative combination of ketamine and magnesium sulfate infusions on postoperative analgesia in patients undergoing open rhinoplasty.
- Conditions
- Intraoperative, Ketamine, Magnesium Sulfate, Postoperative Analgesia
- Trial name
- NCT06966518
- Testing
- Ketamine and Magnesium Sulfate, Saline 0.9%
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Rhinoplasty, Pain Management
Efficacy of Liposomal Bupivacaine Post Septorhinoplasty
The objective of this study is to determine if there is a difference in post-operative pain after septorhinoplasty when long-acting liposomal bupivacaine is used for local anesthesia compared to other standard local anesthetic…
- Trial name
- NCT05964868
- Testing
- Liposomal Bupivacaine, 0.25% bupivacaine with 1:200,000 epinephrine
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Jessyka Lighthall
Rhinoplasty, Edema
Effects of Red and Infrared Photobiomodulation in Rhinoplasty at a Single Centre
This single-centre, randomized, double-blind, sham-controlled clinical trial evaluates whether preoperative photobiomodulation (PBM) with red and infrared light can reduce early postoperative periorbital edema in patients…
- Trial name
- NCT07033039
- Testing
- Photobiomodulation, Simulation of Photobiomodulation, Standard treatment protocol
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Rhinoplasty, AI (Artificial Intelligence)
AI in Assessing Aesthetic Outcomes in Rhinoplasty
This study aims to thoroughly assess the predictive accuracy of artificial intelligence-based nasal outcome simulations by comparing AI-generated preoperative predictions with objective postoperative nasal morphology using…
- Trial name
- NCT07580573
- Testing
- AI
- Volunteers
- 20 people
- Sponsor
- Assiut University
Rhinoplasty, Nasal Obstruction
Outcome Analysis in Septorhinoplasty
A prospective observational cohort study that measures pre- and postoperative outcome of septorhinoplasty by means of patient-related outcome measures (PROMS: NOSE, FACE-Q, Utrecht Questionnaire, SCHNOS and BDDQ-AS) as well as…
- Conditions
- Rhinoplasty, Nasal Obstruction, Esthetics
- Trial name
- NCT03925389
- Testing
- External septorhinoplasty
- Where
- Belgium
- Volunteers
- 750 people
- Sponsor
- FRANK DECLAU
Controlled Hypotension for Nasal Surgeries
Effects of Different MAP Targets on Ocular Perfusion and Optic Nerve Microvasculature During Rhinoplasty
This randomized controlled trial aims to evaluate the effects of two different mean arterial pressure (MAP) targets during controlled hypotension on ocular perfusion and optic nerve head microvasculature in patients undergoing…
- Trial name
- NCT07832305
- Testing
- Lower MAP Target Strategy (50-60 mmHg), Higher MAP Target Strategy (60-70 mmHg)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hitit University
Emergence Agitation
Prevention of Emergence Agitation in Rhinoplasty With Subanesthetic Propofol and Single-Dose Dexmedetomidine: A Prospective Double-Blind Clinical Study
To compare of prevention of emergence agitation in rhinoplasty with subanesthetic propofol and single dose dexmedetomidine
- Trial name
- NCT07144007
- Testing
- Dexmedetomidine, Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Surgery, Postoperative Blood Loss
Tranexamic Acid in Rhinoplasty: Perioperative Bleeding, Edema and Ecchymosis
This study will be a prospective randomized study to evaluate the effect of tranexamic acid (TXA) use on intraoperative and postoperative outcomes among patients undergoing rhinoplasty by two Facial Plastic surgeons at…
- Trial name
- NCT05774717
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Nasal Septum Deviation, Rhinoplasty
Effect of Controlled Hypotension on GFAP and Cognition in Rhinoplasty
This prospective observational study aims to evaluate the neurological safety of controlled hypotension (Mean Arterial Pressure 50-65 mmHg) during elective rhinoplasty.
- Conditions
- Nasal Septum Deviation, Rhinoplasty, Induced Hypotension
- Trial name
- NCT07699133
- Testing
- Controlled Hypotension (Standard of Care)
- Volunteers
- 40 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Cleft Lip and Palate, Rhinoplasty
Single Stage Versus Multiple Staged Repair of Nasal & Alveolar Deformities in Patients With Cleft Lip and Palate
Cleft lip and palate patients are commonly seen among maxillofacial patients. Patients with cleft lip and palate have evident cosmetic nasal deformities.
- Trial name
- NCT06510881
- Testing
- Rhinoplasty with or without cleft alveolus repair
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Nasal Valve Collapse, Nose Enhancement
Cartilage Remodeling Using Low-Temperature Radiofrequency for Nasal Airway Reconstruction
The goal of this study is to evaluate the efficacy of using the Vivaer low-temperature radio-frequency (LTRF) device to reshape ex-vivo human nasal or auricular cartilage for use in cosmetic and functional septorhinoplasty.
- Trial name
- NCT07032675
- Testing
- Low-temperature radio-frequency reshaping of autologous cartilage nasal and/or auricular cartilage
- Where
- 6 sites in United States
- Volunteers
- 20 people
- Sponsor
- Indiana University
Nasal Deformity, Rhinoplasty
Patient-Reported Outcomes and Complications After Structural Rhinoplasty Using Septal Extension Grafts
Structural rhinoplasty with septal extension graft (SEG) is commonly used to achieve stable nasal tip support and predictable long-term outcomes.
- Conditions
- Nasal Deformity, Rhinoplasty, Nasal Obstruction
- Trial name
- SEG-PROM (NCT07531810)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Cumhuriyet University Hospital
Nasal Obstruction, Nasal Surgical Procedures
Antibiotic Prophylaxis in Rhinoplasty
This study compares the efficacy of a single intra-operative (intravenous) dose of "cephalexin" (first generation cephalosporin) or "clindamycin" (lincosamides), alone versus both intra-operative (intravenous) dose of…
- Trial name
- NCT04194216
- Testing
- Intra-operative single intravenous(iv) dose of "cephalexin" 2 g or "clindamycin" 900 mg., Intra-operative single dose (iv) of "cephalexin" 2 g or "clindamycin" 900 mg and postoperative oral dose of "cephalexin" 250mg (every 4 hours) or "clindamycin" 150mg(every 6 hours) for 3 days
- Where
- United States
- Volunteers
- 864 people
- Sponsor
- Stanford University