Clinical trials: Prostheses and Implants
Prosthesis Durability
Complete Digital Workflow for Construction of Full Arch Implant Supported Screw Retained Restoration
This study will compare the occlusal accuracy of different techniques for recording maxillomandibular relationships in a Complete digital workflow to construct full arch implant-supported screw-retained restoration.
- Trial name
- NCT06332482
- Testing
- Implant supported screw retained prosthesis
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Upper Extremity Amputee
Peripheral Interfaces in Amputees for Sensorimotor Integration
The purpose of this research is to gather information on the safety and effectiveness of an implanted wireless sensory enabled highly intuitive controlled prosthetic device.
- Trial name
- iSens (NCT04430218)
- Testing
- iSens
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- VA Office of Research and Development
Prosthesis Durability
Direct Versus Indirect Pick up of the Locator Retentive Caps:(Within-patient Study)
The purpose of this study will be to evaluate the effect of direct and indirect pick up of the locator retentive caps and compare the clinical results with those of the manufacturer retentive force.
- Trial name
- NCT05289752
- Testing
- dental implants in the mandible, locator attachment and overdenture
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Amputations, Peripheral Nerve Injury
Micro-Electrodes Implanted in a Human Nerve
The main objective of the intervention in the study is devise feasibility using high-count microelectrode arrays implanted into peripheral nerves of patients with limb amputations or peripheral nerve injury.
- Conditions
- Amputations, Peripheral Nerve Injury, Spinal Cord Injury
- Trial name
- NCT02034461
- Testing
- Utah Slanted Electrode Array
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Utah
Edentulous Jaws
Computer Assisted Implant Surgery and Immediate Loading
Purpose: The aim of this study was to analyze the clinical and radiographic outcomes of 23 edentulous jaws treated with 3D software planning, guided surgery, immediate loading and restored with Cad-Cam Zirconia and titanium full…
- Trial name
- NCT01866696
- Testing
- oral implants
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Università degli Studi di Sassari
Prostheses, Endosseous Dental Implant Failure
Pink Esthetic Score Around Immediate Implants Using PDDM as Jumping Gap Filling Material.
Will there be a difference in Pink Esthetic score and soft tissue changes around immediate implants in maxillary esthetic zone following grafting the jumping gap with partially demineralized dentin matrix compared with xenograft?
- Trial name
- NCT05952765
- Testing
- Immediate implant
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Prosthesis, Implant-Supported
A Retrospective Data Collection on NobelProcera® Zirconia Implant Bridges from 4 to 14 Units.
This is a retrospective multicenter data collection in which clinical and radiographic data on implant zirconia bridges are collected from partially or fully edentulous subjects consecutively treated with at least one 4- to…
- Trial name
- NCT06600451
- Testing
- observational study, no intervention is required
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nobel Biocare
Otorhinolaryngologic Diseases
Reconstruction Implant Bone After Removal Using Porous Titanium Prosthesis
This trial will study the reconstruction of the anterior part of the mandible and the adjacent soft tissue parts by a mandibular prosthesis made in porous titanium, associated or not, to a latissimus dorsi or pectoral flap, to…
- Trial name
- NCT00213837
- Testing
- Mandibular prosthesis made of a new highly biointegratable material
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Strasbourg, France
Edentulism, Implant Dentistry
Marginal Bone Remodeling at Monolithic Zirconia Full-Arch Prostheses in the Maxilla and Mandible
This prospective observational clinical study aims to compare 12-month clinical, radiographic, and patient-reported outcomes of monolithic zirconia full-arch implant-supported prostheses placed in the maxilla versus the mandible.
- Trial name
- NCT07323290
- Testing
- No intervention
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Staphylococcal Infections, Joint Prosthesis
StaphVAX Immunogenicity in Orthopedic Implant Patients
S. aureus is the most common pathogen involved in prosthetic joint infection. StaphVAX® is a vaccine to prevent these infections, which conjugates the purified capsular polysaccharides of S. aureus to a carrier protein.
- Trial name
- NCT00211926
- Testing
- S. aureus Type 5 & 8 Capsular Polysaccharide Conjugate
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nabi Biopharmaceuticals
Prosthesis Related Infection
Contribution of the Sonication of Implants to the Diagnosis of Joint Prosthesis Infection: A Retrospective Cohort Study
Studies on sonication suffer from a heterogeneity which makes their analysis complex, due to the absence of a gold standard allowing positive cases to be defined unequivocally.
- Trial name
- SonicHUS (NCT05867108)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Dental Implants, Dental Materials
Hybrid Polyetheretherketone (PEEK)-Acrylic Resin Prostheses and the All-on-4 Concept for Full Arch Rehabilitation
It is necessary to evaluate the outcome of implant supported fixed prosthetic rehabilitations using peek material. To test this, the study design to be used will be a prospective single cohort to evaluate the long term outcome of…
- Conditions
- Dental Implants, Dental Materials, Mandible, Prosthesis Survival
- Trial name
- AO4PEEKDev (NCT04446078)
- Testing
- PEEK- acrylic resin prosthesis supported by 4 dental implants
- Where
- Portugal
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Malo Clinic
Knee Arthritis, Knee Osteoarthritis
In-vivo Wear Behaviour of AS Coated Versus Uncoated Columbus® Total Knee Prosthesis
This clinical study is a Post-Market Clinical Follow-Up (PMCF) measure and is aiming to compare the in-vivo wear behaviour of the Columbus® total knee prosthesis between the standard Cobalt Chromium (CoCr) and the multilayer…
- Conditions
- Knee Arthritis, Knee Osteoarthritis, Primary Osteoarthritis of Knee Nos, Secondary Osteoarthritis of Knee Nos
- Trial name
- COLRAS (NCT05509972)
- Testing
- total knee prosthesis implantation
- Where
- Germany
- Volunteers
- 7 people
- Sponsor
- Aesculap AG
Implant Site Reaction, Implant Complication
Retention, Chewing Efficiency and Masticatory Performance of Partial Dentures Opposing Implant Retained Prosthesis.
This study aims to evaluate retention ,chewing efficiency and masticatory performance of flexible versus CAD/CAM partial dentures opposing to fixed implant retained restorations.
- Trial name
- NCT05999760
- Testing
- evaluation of retention of Versacryle and CAD/CAM partial dentures by force gauge, chewing efficiency by electromyograph(E.M.G), masticatory performance(questionnaire)
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- National Research Centre, Egypt
Implant Infection
Maintenance Protocol for Implant Supported Hybrid Prosthesis.
The study we intend to carry out aims to analyze the clinical and microbiological effects of a new maintenance protocol for implant-supported hybrid prostheses.
- Trial name
- NCT05482490
- Testing
- Maintenance protocol for the hygiene of implant supported prosthesis
- Where
- Italy
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Age Related Macular Degeneration
Study of WA-NG Telescope Prosthesis in Patients With End-stage Age-related Macular Degeneration
This is a pilot study to evaluate the safety of the Model WA-NG telescope prosthesis in patients with bilateral moderate to profound central vision impairment due to end-stage age-related macular degeneration.
- Trial name
- NCT01731964
- Testing
- Telescope prosthesis, WA-NG Telescope Prothesis
- Where
- Israel
- Sponsor
- VisionCare, Inc.
Funnel Chest
Evaluation of a New Model of Metallic Bar and Stabilizer for Use in MIRPE
Pectus excavatum (PE) is the most common deformity of the chest wall, occurring in approximately 1/1000 people. Currently, surgical treatment by minimally invasive technique is consolidating as preferred technique for the…
- Trial name
- NCT03087734
- Testing
- Implantation of new model of bar with oblique stabilizers, Implantation of regular bar with perpendicular stabilizers
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Peri-implant Mucositis, Peri-Implantitis
Peri-implant Disease and Prosthetic Cement: Cross-sectional Study
The main objective of the present clinical study project, of a cross-sectional observational nature, is to evaluate the presence of submucosal cement residues through endoscopic visualization in clinical situations with…
- Trial name
- NCT05945836
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- University of Bologna
Vestibular Disorder, Bilateral Vestibulopathy
Electrical Stimulation of the Peripheral Vestibular System in Order to Develop a Vestibular Implant
This study has three main goals (1) to explore the effects of electrical stimulations of the peripheral vestibular system(2) to assess the potential of this technique to rehabilitate basic vestibular functions in patients with…
- Conditions
- Vestibular Disorder, Bilateral Vestibulopathy, Bilateral Vestibular Loss
- Trial name
- NCT05246553
- Testing
- Electrical stimulation of the vestibular system, Electrical stimulation of the auditory system, Bilateral vestibulopathy Patients (BV)
- Where
- Switzerland
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Nils Guinand
Testicular Cancer, Testicular Torsion
Prospective Observational Study on SEBBIN Silicone Gel-filled Testicular Implants
To analyze the short and long term postoperative clinical outcome and patient satisfaction of silicone gel-filled testicular implants.
- Conditions
- Testicular Cancer, Testicular Torsion, Gender Dysphoria, Undescended Testes
- Trial name
- NCT05097820
- Testing
- Placement of testicular prosthesis
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent