Clinical trials: Prolapse
Pelvic Organ Prolapse, Symptoms
Evaluation of Functional Outcomes After Laparoscopic Promontofixation (PFL).
Prolapse of the pelvic organs is a common pathology in women with a strong impact on the quality of life. Its prevalence tends to increase due to increased life expectancy and obesity.
- Conditions
- Pelvic Organ Prolapse, Symptoms, Satisfaction, Quality of Life
- Trial name
- PeSuLife (NCT03919123)
- Testing
- Evaluation of laparoscopic promontofixation
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Caen
Stress Urinary Incontinence, Vaginal Hysterectomy
Vaginal Prolapse Surgery Accompanied by Mid Urethral Sling Versus no Sling for Reduction of Postoperative Incontinence
Prevalence of pelvic organ prolapsed is high in Nepal. After prolapse surgery many patients are affected with incontinence. Incontinence has physical, social and mental effect to the individual.
- Conditions
- Stress Urinary Incontinence, Vaginal Hysterectomy, Quality of Life
- Trial name
- NCT04251923
- Testing
- Retro pubic sling
- Volunteers
- 56 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Mitral Valve Prolapse Syndrome, Arrhythmogenic Bileaflet Mitral Prolapse
Mitro-annular Disjunction in Cardiac Magnetic Resonance
Mitral annular disjunction (MAD) is an abnormal atrial displacement of the mitral valve leaflet hinge point. MAD is gaining clinical importance for several studies reporting its association to mitral valve prolapse (MVP), complex…
- Conditions
- Mitral Valve Prolapse Syndrome, Arrhythmogenic Bileaflet Mitral Prolapse, Mitral Valve Disorder
- Trial name
- NCT06436573
- Where
- Italy
- Volunteers
- 4,000 people
- Sponsor
- IRCCS San Raffaele
Pelvic Organ Prolapse, Gynecologic Disorders
Comparison of Learning Curves for Two Different Techniques in Vaginal Hysterectomy
Randomized prospective monocentric interventional study to compare learning curves for traditional vaginal hysterectomy and vaginal hysterectomy performed by bipolar coagulation comparing short-term outcomes for both procedures.
- Conditions
- Pelvic Organ Prolapse, Gynecologic Disorders, Surgery
- Trial name
- NCT06220253
- Testing
- vaginal hysterectomy by bipolar vessels sealing, vaginal hysterectomy by traditional technique
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Prolapse
Outcomes After Sacrocolpopexy With and Without Burch to Prevent Stress Urinary Incontinence in 3rd and 4th Degree Apical Uterine Prolapse
Urinary incontinence will develop after prolapse repair in approximately one quarter of patients with advanced pelvic organ prolapse who remain continent despite significant loss of anterior vaginal and pelvic organ support.
- Trial name
- NCT03609229
- Testing
- Burch, Abdominal Sacrocolpopexy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Pelvic Organ Prolapse, Prolapse
A New POP (Pelvic Organ Prolapse) Scoring System: Validity and Reliability
There is a strong need for a better, simplified and informative applicable classification system that should be used to speak a common descriptive language among health care providers that treat POP.
- Conditions
- Pelvic Organ Prolapse, Prolapse, Prolapse, Vaginal, Prolapse Uterus
- Trial name
- NCT06520722
- Testing
- Prolapse scoring system
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Cairo University
Myocardial Protection, Minimally Invasive Surgery
Myocardial Protection in Minimally Invasive Mitral Valve Surgery
Perfusion strategies and aortic clamping techniques for right mini-thoracotomy mitral valve (MV) surgery have evolved over time and remarkable short- and long-term results have been re-ported.
- Conditions
- Myocardial Protection, Minimally Invasive Surgery, Mitral Valve Prolapse
- Trial name
- NCT04231903
- Testing
- Aortic clamp
- Volunteers
- 116 people
- Sponsor
- University of Turin, Italy
Brow Ptosis, Skin Aging
Single-Session Microfocused Ultrasound, AbobotulinumtoxinA and Temporal Hyaluronic Acid Filler for Non-Surgical Brow Lifting
This observational study describes the results of a routine aesthetic treatment for mild to moderate eyebrow drooping (brow ptosis).
- Conditions
- Brow Ptosis, Skin Aging, Facial Aging
- Trial name
- NCT07894822
- Testing
- Microfocused ultrasound with visualization, AbobotulinumtoxinA, Hyaluronic acid filler
- Where
- Russia
- Volunteers
- 36 people
- Sponsor
- Estelab Clinic
Pelvic Organ Prolapse
A Study of the Effects of Physiotherapy to Prevent Pelvic Organ Prolapse
Pelvic organ prolapse is a problem experienced by women where a bulge comes down in the vagina, and may even drop down outside the vagina.
- Trial name
- PREVPROL (NCT01171846)
- Testing
- Pelvic Floor Muscle training
- Where
- 3 sites in New Zealand, United Kingdom
- Volunteers
- 337 people
- Sponsor
- Glasgow Caledonian University
Eyelid Diseases, Ptosis, Eyelid
Telemedicine Follow-up for Routine, Low-Risk Oculoplastic Surgery
The investigators propose utilizing a simple telemedical protocol to allow patients to substitute the first post-operative visit with a remote survey that includes essential post-operative history, vision measurement, and…
- Conditions
- Eyelid Diseases, Ptosis, Eyelid, Blepharoptosis, Dermatochalasis
- Trial name
- NCT04235803
- Testing
- Telemedicine follow-up
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of California, San Francisco
Dermatochalasis, Blepharoptosis
Vibration-Assisted Anaesthesia
Aim of study is to investigate whether a small, non-invasive vibrating device applied to the forehead during local anaesthetic administration reduces the pain of the injection.
- Trial name
- NCT00793988
- Testing
- Vibration-assisted anaesthesia, Switched-off vibrating device
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pelvic Organ Prolapse, Urinary Incontinence,Stress
Timing of Repeat Voiding Trials After Outpatient Pelvic Floor Surgery
This study is a randomized controlled trial designed to assess the rate of failure of voiding trials in the early and late post-operative period within patients who underwent outpatient pelvic floor surgery that failed initial…
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence,Stress, Surgery
- Trial name
- NCT03048682
- Testing
- Foley catheter - Early Voiding Trial, Foley catheter - Late Voiding Trial
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- The Cleveland Clinic
Sexuality, Sexual Dysfunction
Improving Female Sexual Wellness
The purpose of this study is to assess the effect of commercially available genital vibrator use on sexual health, female pelvic floor disorders, and overall quality of life among a diverse population of women.
- Conditions
- Sexuality, Sexual Dysfunction, Sexual Desire Disorder, Hypoactive Sexual Desire Disorder
- Trial name
- NCT04824820
- Testing
- Vibrator
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Cedars-Sinai Medical Center
Sacrospinofixation, Apical Prolapse
Concordance of Pelvic Organ Mobility Measurements Between the Finite Element Model and the Dynamic Pelvic Floor MRI in Patients Undergoing a Sacrospinofixation Surgery
The primary objective of this study is to demonstrate the feasibility of using a Finite Element model of pelvic organs by evaluating the concordance of pelvic organ mobility measurements performed by this mechanical model…
- Trial name
- BiomécaRichter (NCT04551859)
- Testing
- Dynamic Pelvic Floor MRI
- Volunteers
- 41 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon