Clinical trials: Pregnancy Preterm
Placenta Accreta
Lower Placental Edge Thickness in Relation to Gestational Age at Delivery in Placenta Accreta (Prospective Cohort Study)
The aim of our study is to determine correlation between lower placental edge thickness measured by ultrasound and gestational age at delivery and predict the risk of emergency preterm birth in patients having placenta previa…
- Trial name
- NCT06248385
- Testing
- 2D ultrasound
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Premature Birth
A Longitudinal Study of Effectiveness of Early Intervention for Preterm Infants
The main purpose of this study is to extend the investigators' previous research to longitudinally examine the effectiveness of three early intervention programs: usual care program, clinic-based intervention program and…
- Trial name
- NCT00946244
- Where
- Taiwan
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Prematurity; Extreme
Risk of Chronic Diseases in Young Adults Born Preterm: Relationship With Inflammation and Oxidative Stress Biomarkers.
The purpose of the HAPI project is to study the overall health of preterm infants once they reach adulthood. The investigators would like to compare the health of adults born preterm with that of adults born full-term.
- Trial name
- NCT03261609
- Testing
- preterm birth
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Preterm Birth, Tube Feeding
Maternal Role in Oral Feed Establishment in Preterm Neonates
Hypothesis Preterm babies who receive sensory motor stimulation from their mothers as compared to trained nurses will 1. Start taking oral feed at the same time as compared to control group 2.
- Conditions
- Preterm Birth, Tube Feeding, Swallowing Disorder, Maternal Care Patterns
- Trial name
- NCT05484726
- Testing
- perioral sensory motor stimulation
- Where
- Pakistan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Fatima Memorial Hospital
Acute Respiratory Distress Syndrome Related to SARS-CoV-2
COronaVirus Induced Acute Respiratory Disease Syndrome During PREGnancy
Few data are available on the management of critically ill pregnant women with pneumonia related to SARS-CoV-2. In the absence of clear recommendations for the management of delivery, clinicians are faced with the risk of…
- Trial name
- COVADIS-PREG (NCT05193526)
- Testing
- No intervention
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Obstetric Labour, Premature
The Safety, Tolerability And Metabolism Of GSK221149A, In Pregnant Women (30-36 Weeks), In Pre-Term Labor
Pre-Term Labor (prior to 37 weeks gestation) is the largest single cause of infant morbidity and mortality and is frequently associated with long-term disability. Oxytocin is a hormone produced by the body during labor.
- Trial name
- NCT00404768
- Testing
- GSK221149A
- Where
- 57 sites in United States, Argentina and 9 more
- Volunteers
- 93 people
- Sponsor
- GlaxoSmithKline
Preterm Birth, Cervix; Pregnancy
Prospective Evaluation of Pathways for Preterm Birth
This is a single center, prospective cohort study of pregnant patients at high risk for spontaneous preterm birth: patient's with history of spontaneous preterm birth, patient's with a short cervix and patient's symptomatic for…
- Trial name
- PEPP (NCT05246579)
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- John O'Brien, MD
Preterm Birth, Visual Impairment
Eye and Growth in Adolescents Born Moderate-to-late Preterm
During recent years, the interest in studying the risks of being born moderate-to-late preterm (MLP), defined as birth between gestational week 32 to 36, has increased.
- Conditions
- Preterm Birth, Visual Impairment, Eye Abnormalities
- Trial name
- NCT04190147
- Testing
- Structural, functional and metabolic eye examinations
- Where
- Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Cervical Insufficiency, Preterm Birth
Optimal Timing of Routine Cervical Length Measurements During Anatomy Survey
The goal of this clinical trial is to determine the optimal timing for measuring cervical length (CL) during fetal anatomy surveys in pregnant individuals.
- Conditions
- Cervical Insufficiency, Preterm Birth, Cervical Length Measurement
- Trial name
- NCT06822647
- Testing
- Cervical Length Measurement at the Beginning of the Anatomy Survey, Cervical Length Measurement at the End of the Anatomy Survey
- Where
- United States
- Volunteers
- 550 people
- Sponsor
- Henry Ford Health System
Pulse Oximetry, Disparities
Beyond Race: Objectively Assessed Skin Color and Its Association With Pulse Oximeter Bias in Critically Ill Infants
The overall objective of this proposal is to quantify the bias in pulse oximeter reported oxygen saturation (SpO2) by evaluating its measures compared to the gold standard blood gas measured arterial oxygen saturation (SaO2)…
- Conditions
- Pulse Oximetry, Disparities, Infants
- Trial name
- NCT05994417
- Volunteers
- 200 people
- Sponsor
- Arkansas Children's Hospital Research Institute
Hypothermia, Preterm Infants
Heat Loss Prevention in Delivery Room Using a Polyethylene Cap
It is apparent that the head of a preterm infant should not be left uncovered, however it remains unclear whether covering the head of a preterm baby with plastic wrapping is effective in preventing heat loss.
- Trial name
- NCT00930917
- Testing
- Polyethylene cap, Polyethylene wrap, conventional treatment
- Volunteers
- 96 people
- Sponsor
- University of Padova
Fetal Heartbeat Tracings
Comparing Two Methods of Contractions Monitoring for Clinical Decision Making Regarding Treatment Among Pregnant Women With Preterm Contractions.
Background: Identification and measurement of uterine contractions throughout pregnancy and labor is crucial to the well being of both mother and fetus.
- Trial name
- NCT02875418
- Testing
- EUM, Tocodynamometry
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Premature Birth
2-Brain Regulation to Achieve Improved Neuroprotection During Early Development
Each year 15 million infants are born preterm (PT). Even without severe comorbidities, they are exposed to sensory stress during the Neonatal Intensive Care Unit (NICU) stay and are at greater risk of neurodevelopmental problems…
- Trial name
- 2-BRAINED (NCT06659809)
- Testing
- Tele-care video-feedback intervention (TVFI)
- Where
- 2 sites in Italy
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Respiratory Distress Syndrome, Newborn
Feasibility Study of Placement and Surfactant Administration Through a Preterm Size Laryngeal Mask Airway in Very Low Birth Weight Neonates With Respiratory Distress Syndrome
Surfactant administration via a supraglottic airway device or laryngeal mask airway (SALSA) is a minimally invasive method of instilling surfactant in the trachea during spontaneous breathing and after applying nasal continuous…
- Trial name
- NCT06606444
- Testing
- Surfactant Administration Through Laryngeal or Supraglottic Airways
- Where
- Vietnam
- Volunteers
- 45 people
- Sponsor
- Karolinska Institutet
Preterm Rupture of Membranes
Trace Elements and Heavy Metals at PPROM
Objectives: To evaluate maternal serum trace elements and heavy metals namely, aluminum (Al), chromium (Cr), manganese (Mn), cobalt (Co), nickel (Ni), copper (Cu), zinc (Zn), arsenic (As), molybdenum (Mo), cadmium (Cd), tin (Sn)…
- Trial name
- metals&PROM (NCT04077944)
- Testing
- maternal serum concentration of trace elements and heavy metals levels
- Where
- Turkey (Türkiye)
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Cengiz Gokcek Women's and Children's Hospital
Respiratory Distress Syndrome, Chronic Lung Disease of Prematurity
Prevention of Chronic Lung Disease (CLD) in Preterm Infants
Pulmonary inflammation plays an important role in the early development of CLD. Postnatal glucocorticoids have been shown effective in the prevention or treatment of CLD with various success.
- Trial name
- NCT00883532
- Testing
- budesonide
- Where
- China
- Volunteers
- 300 people
- Sponsor
- China Medical University, China
Patent Ductus Arteriosus
International Experience in Timing And Choices for Ductal Closure in Patent Ductus Arteriosus:INTERPDA Trial
The three options for the treatment of patent ductus arterioles (PDA) in preterm infants are conservative approach, pharmacological intervention and surgical ligation.
- Trial name
- NCT02910609
- Testing
- Echocardiography
- Volunteers
- 1,000 people
- Sponsor
- Ankara University
Previous Mid Trimester Miscarriage, Previous Preterm Birth
Arabin Pessary in Singleton Pregnancy
This was a retrospective study sharing the experience of women high risk for spontaneous preterm birth managed by Arabin pessary.
- Conditions
- Previous Mid Trimester Miscarriage, Previous Preterm Birth, Previous Cervical Surgery, Short Cervix on Ultrasound
- Trial name
- NCT04638023
- Testing
- Arabin pessary
- Where
- Malaysia
- Volunteers
- 58 people
- Sponsor
- National University of Malaysia
Apnea, Bradycardia
microEEG for Neonatal Apnea, Bradycardia and Desaturation
The study utilizes microEEG (a novel miniaturized, FDA approved EEG device) to prospectively investigate the cerebral electrical activity of infants with Apnea, Bradycardia and Desaturation events.
- Conditions
- Apnea, Bradycardia, Premature Birth, Seizures
- Trial name
- NCT02436616
- Testing
- microEEG
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Bio-Signal Group Corp.
Respiratory Viral Infections, Adverse Pregnancy Outcomes
APOs Associated With Respiratory Viral Infections Before and During Early Pregnancy
Adverse pregnancy outcomes (APOs) are a collection of conditions that have short-term and long-term effects of complications related to pregnancy and childbirth on pregnant women and their fetuses, including hypertensive…
- Trial name
- APO (NCT07257952)
- Volunteers
- 1,440 people
- Sponsor
- Shanghai General Hospital, China