Clinical trials: Pregnancy Early
Endometrial Neoplasms, DNA Methylation
Cervical Cytology DNA Methylation for Endometrial Lesion Screening and Follow-up
The goal of this observational study is to evaluate the accuracy of a novel molecular test for screening and monitoring endometrial lesions in women at medium-to-high risk for endometrial cancer.
- Conditions
- Endometrial Neoplasms, DNA Methylation, Cervical Smears, Early Detection of Cancer
- Trial name
- EndoMethy-V (NCT07298707)
- Volunteers
- 3,500 people
- Sponsor
- Peking Union Medical College Hospital
Chronic Kidney Disease
A Study on Patients With Chronic Kidney Disease (CKD) to Assess Treatment Experience and Patterns, Effect of the Treatment, Patient Outcomes and Patient Quality of Life
DISCOVER CKD is an international observational cohort study in patients with CKD, comprising both prospective and retrospective patient cohorts.
- Trial name
- NCT04034992
- Where
- 43 sites in United States, Italy and 4 more
- Volunteers
- 1,052 people
- Sponsor
- AstraZeneca
Hypertension, Chronic Kidney Disease.
Effect of Eplerenone in Elderly Hypertensive Early Stage Chronic Kidney Disease (CKD) Patients
The purpose of this study is to determine whether eplerenone is effective in the treatment of blood pressure, heart function, renal function in elderly hypertensive stage1 (eGFR>=90ml/min/1.73m2) and stage2 (eGFR…
- Trial name
- NCT01302236
- Testing
- Eplerenone
- Sponsor
- Jichi Medical University
Diabetic Kidney Disease
To Improve the Ability of Early Screening and Diagnosis in Patients With Diabetic Nephropathy
This is a large-scale, multi-center, observational study. It is planned to establish a large database of 10,000 patients with type 2 diabetes mellitus to investigate the prevalence, awareness and screening rates of diabetes…
- Trial name
- NCT05047471
- Where
- 50 sites in China
- Volunteers
- 10,000 people
- Sponsor
- Yiming Mu
Infertility, Female
Time-lapse Monitoring of Early Embryo Development After Ovarian Stimulation During Infertility Treatment
The number of children conceived by assisted reproductive technology is increasing in Nordic countries as well as worldwide. An important factor of success in treatment of infertility is a short "time to pregnancy" with impact on…
- Trial name
- NCT01882166
- Testing
- fostimon, puregon
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- St. Olavs Hospital
Ovarian Cancer, Liquid Biopsy
Setting Up ctDNA Analysis on Archived Plasma Samples
This study (DARE part 1) is a single-center, retrospective, observational feasibility study promoted by the Fondazione Policlinico Universitario Agostino Gemelli IRCCS and co-funded by Fondazione AIRC, aimed at evaluating the…
- Trial name
- DARE-part1 (NCT07546578)
- Testing
- ctDNA
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Ovarian Cancer
Pilot Study to Evaluate 18F-fluorodeoxyglucose (FDG) Positron Emission Tomography /Computed Tomography (PET/CT) in Prediction of Early Response to Chemotherapy in Ovarian Cancer.
We hypothesize that 18FDG Positron Emission Tomography (FDG PET) imaging, carried out after the first cycle of chemotherapy, will identify responders, thus permitting early termination of potential toxic therapy in non…
- Trial name
- NCT00620243
- Testing
- 1: FDG PET
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Retinopathy of Prematurity
Oral Propranolol Versus Placebo for Early Stages of Retinopathy of Prematurity: A Randomized and Prospective Study
In premature infants, propranolol (Prop) treatment might suppress continuing neo-vascularization (NV) and decelerate the progression of retinopathy of prematurity (ROP) towards its severe stages (III-V), thus avoiding the need of…
- Trial name
- NCT01238471
- Testing
- propranolol, sucrose 5%
- Where
- 4 sites in Israel
- Volunteers
- 20 people
- Sponsor
- Rambam Health Care Campus
Spontaneous Abortion, Oxidative Stress
Heavy Metals' Influence on Early Pregnancy Through Oxidative Stress
Patients with diagnosis of spontaneous abortion are enrolled in the cohort, in the cohort of patients who met the criteria, 3ml of whole blood intravenous and 5ml of urine were taken for heavy metal level examnation.
- Trial name
- NCT04003064
- Testing
- Blood
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking Union Medical College Hospital
Infertility, Female
A New Revolutionary 3-Injection- Protocol in Infertile Women
This is a prospective randomised study of the evaluation of the clinical IVF results after following a new revolutionary 3-Injection- Protocol for controlled ovarian stimulation in infertile women.
- Trial name
- NCT03877185
- Testing
- Live birth rate
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assisting Nature
Oxytocin
The Effect of Labor Induction With Oxytocin on Early Postpartum Hemorrhage, Perineal Integrity and Breastfeeding
Aim: This study has been planned as an observational study. The aim of this study is to determine the effect of labor induction with oxytocin on early postpartum hemorrhage, perineal integrity and breastfeeding.
- Trial name
- NCT04441125
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Saglik Bilimleri Universitesi
Premature Birth
A Longitudinal Study of Effectiveness of Early Intervention for Preterm Infants
The main purpose of this study is to extend the investigators' previous research to longitudinally examine the effectiveness of three early intervention programs: usual care program, clinic-based intervention program and…
- Trial name
- NCT00946244
- Where
- Taiwan
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Urinary Bladder Neoplasms
GreenBladder - Early Detection of Bladder Cancer in Residents in Greenland Using a Urinary Marker and a Mobile Cystoscopy Unit
The goal of this observational study is to evaluate whether a urinary biomarker (Xpert® Bladder Cancer Detection Test) can be used as a selection tool to decide which patients that should undergo cystoscopy in haematuria work-up…
- Trial name
- NCT06281691
- Testing
- Xpert® Bladder Cancer Detection Test
- Where
- 2 sites in Denmark, Greenland
- Volunteers
- 127 people
- Sponsor
- Jørgen Bjerggaard Jensen
Kidney Impairment
Study to Evaluate Blood and Urine Kidney Injury Markers to Facilitate Early Detection of Renal Adverse Drug Events in Pediatric Cancer Patients Treated With Nephrotoxic Chemotherapy
This study is to investigate blood and urine kidney injury markers (especially Uromodulin) in pediatric cancer patients treated with nephrotoxic chemotherapy.
- Trial name
- Kid-MaCareOnco (NCT04308642)
- Testing
- blood test for renal biomarkers, urine test for renal biomarkers
- Where
- Switzerland
- Volunteers
- 6 people
- Sponsor
- University Hospital, Basel, Switzerland
Malignant Tumor of Cervix, Cervical Intraepithelial Neoplasia
Participation in Screening for Cervical Cancer: Interest of a Self-sampling Device Provided by the General Practitioner
This study evaluates the benefit in women aged from 30 to 65 years, who do not participate to the French opportunistic cervical cancer screening program, of an organized screening with the proposition by the family physician of a…
- Trial name
- PaCUDAHL-Gé (NCT02749110)
- Testing
- Vaginal self-sampling brush
- Where
- France
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Endometrial Carcinoma Stage I, Atypical Endometrial Hyperplasia
Patient-derived Tumor-like Cell Clusters Predict Progesterone Sensitivity in Patients With Early Endometrial Cancer
To construct a prediction model of progesterone sensitivity in patients with endometrial cancer treated with fertility preservation
- Trial name
- NCT05647109
- Testing
- No intervention
- Where
- China
- Volunteers
- 244 people
- Sponsor
- Peking University People's Hospital
Premature Birth
2-Brain Regulation to Achieve Improved Neuroprotection During Early Development
Each year 15 million infants are born preterm (PT). Even without severe comorbidities, they are exposed to sensory stress during the Neonatal Intensive Care Unit (NICU) stay and are at greater risk of neurodevelopmental problems…
- Trial name
- 2-BRAINED (NCT06659809)
- Testing
- Tele-care video-feedback intervention (TVFI)
- Where
- 2 sites in Italy
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Lactation Disorders
The Relationship Between Oxytocin Massage in Mothers With Insufficient Milk Production in the Early Postpartum Period and Breastfeeding Self-Efficacy and Milk Let-down Reflex: A Randomized Controlled Study
This randomized controlled trial aims to evaluate the effects of oxytocin massage on breastfeeding self-efficacy and the milk ejection reflex among mothers experiencing insufficient milk supply in the early postpartum period.
- Trial name
- NCT07609693
- Testing
- Oxytocin Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Respiratory Viral Infections, Adverse Pregnancy Outcomes
APOs Associated With Respiratory Viral Infections Before and During Early Pregnancy
Adverse pregnancy outcomes (APOs) are a collection of conditions that have short-term and long-term effects of complications related to pregnancy and childbirth on pregnant women and their fetuses, including hypertensive…
- Trial name
- APO (NCT07257952)
- Volunteers
- 1,440 people
- Sponsor
- Shanghai General Hospital, China
Preterm Pregnancy, Antenatal Corticosteroid
The Effect Of Antenatal Corticosteroids On Early And Late Perinatal Outcomes
In this study, the investigators aims to evaluate whether antenatal corticosteroid administration to women likely to give birth in the late preterm period will reduce early and late neonatal complications and contribute to the…
- Conditions
- Preterm Pregnancy, Antenatal Corticosteroid, Perinatal Problems
- Trial name
- NCT06164080
- Testing
- participants receiving Corticosteroid
- Where
- Turkey (Türkiye)
- Volunteers
- 459 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
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