Clinical trials: Pregnancy, Ectopic
Genital Diseases, Female, Ectopic Pregnancy
Randomized Study of a Dematerialized Management for Post-Emergency Gynecological Follow-Up
The GYNAB study aims to compare patient satisfaction and clinical outcomes between dematerialized post-emergency gynecological follow-up using a connected health app and traditional in-person follow-up. Conducted by Drs.
- Conditions
- Genital Diseases, Female, Ectopic Pregnancy, Uncertain Viability of Pregnancy, Abortion, Missed
- Trial name
- GYNAB (NCT06615843)
- Testing
- Participants will receive post-emergency gynecological follow-up at home using a connected health app
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ectopic Pregnancy
Sequential vs. Combined Letrozole and Methotrexate for Tubal Ectopic Pregnancy.
This study evaluates two medical strategies designed to minimize surgical intervention and reduce methotrexate (MTX) exposure in women with undisturbed tubal ectopic pregnancy (TEP).
- Trial name
- NCT07842796
- Testing
- Letrozole, Methotrexate
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Benha University
Benign Gynecological Disease, Uterine Fibroids
Prospective Perioperative Clinical Registry for Women Undergoing Benign Gynecological Surgery
This prospective observational registry aims to systematically collect preoperative, intraoperative, and postoperative clinical data from patients undergoing surgery for benign gynecological conditions.
- Conditions
- Benign Gynecological Disease, Uterine Fibroids, Endometriosis, Adenomyosis
- Trial name
- OPGYNBEN (NCT07772076)
- Testing
- Standard Surgical Procedures for Benign Gynecological Conditions
- Where
- Italy
- Volunteers
- 6,000 people
- Sponsor
- IRCCS San Raffaele
Pregnancy of Unknown Location (PUL)
Expediting Pregnancy of Unknown Location Risk Stratification Using the ROM-Plus Point of Care Test
The goal of this study is to learn if the ROM-Plus bedside test can effectively triage patients who present with pregnancy of unknown location (PUL) and vaginal bleeding as high or low risk for ectopic pregnancy.
- Trial name
- NCT07519954
- Testing
- ROM-Plus bedside test
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Salpingectomy, Hysterectomy
Analysis of the Molecular Composition of Tubal Cilia in Patients With or Without Ectopic Pregnancy
Primary Ciliary Dyskinesia associated with abnormalities of lateralization of organs (with existence of a situs inversus in 50% of cases) and secondary fertility disorders related in humans to abnormalities of mobility of sperm…
- Conditions
- Salpingectomy, Hysterectomy, Primary Ciliary Dyskinesia, Ectopic Pregnancy
- Trial name
- CILTUBE (NCT05374720)
- Testing
- salpingectomy, hysterectomy
- Where
- France
- Volunteers
- 61 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Ectopic Pregnancy
Letrozole Versus Methotrexate for Management of Undisturbed Ectopic Pregnancy
The aim of work is to study the effectiveness of letrozole in treatment of early undisturbed ectopic pregnancy in comparison with Methotrexate.
- Trial name
- NCT07624903
- Testing
- Methotrexate (drug), Letrozole 2.5Mg Tab
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Kafrelsheikh University
To Validate a Decision Aid for Ectopic Pregnancy
Development and Validation of a Therapeutic Decision Aid in Ectopic Pregnancy: GEUDECID Study
The aim's study is to validate a therapeutic aid in women with a less active ectopic pregnancy. A prospective recrutement of 100 women will be performed in 16 different hospitals in France.
- Trial name
- GEUDECID (NCT05745831)
- Testing
- Therapeutic decision tool
- Where
- 15 sites in France
- Volunteers
- 109 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Ectopic Pregnancy
Doppler Flow in Tubal Ectopic Pregnancy in Diagnosis as a Predictor of Treatment Success - Conservative and MTX Treatment
The study "Doppler Flow in Tubal Ectopic Pregnancy as a Predictor of Treatment Success: Conservative and MTX Therapy" aims to evaluate the role of Doppler ultrasound parameters (RI, PI, and PSV) in predicting treatment success…
- Trial name
- NCT07541937
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Meir Medical Center
Pregnancy of Unknown Location
Hysteroscopy for the Diagnosis and Treatment of Pregnancy of Unknown Location
Infertility patients have a higher baseline risk of ectopic pregnancy compared to the general population. If an early pregnancy is not visible by ultrasound, patients with a pregnancy of unknown location (PUL) will undergo…
- Trial name
- NCT07469605
- Testing
- Hysteroscopy for diagnosis and treatment of pregnancy of unknown location
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pennsylvania
Ectopic Pregnancy
Reproductive Health Education, Birth Control and Sexual Quality of Life in Ectopic Pregnancy
Ectopic pregnancy (EP) is defined as the implantation of a fertilized ovum outside the uterine cavity, most commonly in the fallopian tubes.
- Trial name
- NCT07431411
- Testing
- Reproductive Health Counseling and Educational Brochure
- Volunteers
- 102 people
- Sponsor
- Buket Kömürcü
Ectopic Pregnancy
The Effect of Subclinical Dose of Ketamine on Early Postoperative Pain Sensitivity in Patients Undergoing Salpingectomy
The experiment aims to explore the clinical effect of subclinical doses of ketamine on early postoperative pain sensitivity in ectopic pregnancy population.
- Trial name
- NCT06559280
- Testing
- esketamine
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Fujian Provincial Hospital
Non-Viable Pregnancy
Detection of Kisspeptins and miRNAs in Patients With Non-viable Pregnancy
Ectopic pregnancy (EP) is a pathology that affects 3%-16% of pregnancies in humans, being the main cause of morbidity and maternal mortality in the first trimester of pregnancy worldwide.
- Trial name
- TESTKM (NCT03877939)
- Testing
- Blood samples collection for analysis
- Where
- 2 sites in Spain
- Volunteers
- 433 people, healthy volunteers welcome
- Sponsor
- Vida Recoletas Sevilla
Ectopic Pregnancy
Posttraumatic Stress Disorder in Ectopic Pregnancy
The objective of the study is to prospectively assess the prevalence of post-traumatic stress disorder (PTSD) symptoms in a population of women who have experienced a diagnosis of ectopic pregnancy.
- Trial name
- NCT07306689
- Testing
- Impact of Event Scale - Revised (IES-R) questionnaire, Posttraumatic Stress Disorder Checklist - Specific (PCL-S) questionnaire, Trauma Recovery Measure (TRM) questionnaire
- Where
- 2 sites in Poland
- Volunteers
- 200 people
- Sponsor
- Jagiellonian University
Pneumonia, Pleural Effusion
Evaluation of Ultra-portable Ultrasound in General Practice
This is an interventional multi-centre study comparing two groups of general practitioners with or without an ultrasound scanner over a period of 6 months.
- Conditions
- Pneumonia, Pleural Effusion, Renal Colic, Hepatic Colic or Cholecystitis
- Trial name
- EPEMedG (NCT04127149)
- Testing
- Ultrasound scan
- Where
- France
- Volunteers
- 166 people
- Sponsor
- Hospices Civils de Lyon
Ectopic Pregnancy
Methotrexate Treatment in Cases of Ectopic Pregnancy With Relative Contraindications
Study Description (For Patients, Families, and Healthcare Providers) Purpose: The aim of this study is to evaluate the effectiveness and safety of methotrexate treatment in women with ectopic pregnancy who belong to a group for…
- Trial name
- NCT07186127
- Testing
- Drug: Methotrexate (MTX) Patients received methotrexate treatment according to institutional protocols. Dosage and administration routes were recorded retrospectively. For patients who did not respond
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people
- Sponsor
- Bagcilar Training and Research Hospital
Ectopic Pregnancy
Comparison of vNOTES and Laparoscopic Salpingectomy in the Surgical Treatment of Ectopic Pregnancy
This study compares vNOTES salpingectomy and laparoscopic salpingectomy in the treatment of ectopic pregnancy, focusing on outcomes such as operative time, postoperative pain, and recovery.
- Trial name
- vNOTES (NCT07057115)
- Testing
- vNOTES Salpingectomy Group., Laparoscopic Salpingectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Ectopic Pregnancy
Comparison of the Effectiveness of Single-Dose Methotrexate Protocol With Letrozole + Single-Dose Methotrexate in the Medical Treatment of Patients Diagnosed With Ectopic Pregnancy
The objective of the study is to compare the effectiveness of single-dose methotrexate and letrozole + single-dose methotrexate in treating ectopic pregnancy, focusing on treatment success, changes in ß-hCG levels, hemogram and…
- Trial name
- NCT06504082
- Testing
- Letrozole, Methotrexate
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yuzuncu Yil University
Pregnancy, Ectopic, Early Pregnancy Loss
Beta-HCG Levels in Uterine Cavity Lavage for Pregnancies of Unknown Location
The goal of this interventional study is to investigate the role of beta-hCG levels in uterine cavity lavage for differentiating between ectopic pregnancy and early pregnancy loss in female patients aged 18-45 years.
- Trial name
- BHCG-UCL-DEP (NCT07048587)
- Testing
- Beta-hCG levels in the uterine cavity lavage for differential diagnosis in pregnancy of unknown locations and ectopic pregnancy
- Where
- Turkey (Türkiye)
- Volunteers
- 121 people
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Ectopic Pregnancy, Anxiety
Nalbuphine Dosing and Its Impact on Anxiety and Depression in Ectopic Pregnancy Surgery
This prospective, randomized, controlled study aims to evaluate the impact of different doses of nalbuphine on anxiety and depression in patients undergoing surgery for ectopic pregnancy.
- Conditions
- Ectopic Pregnancy, Anxiety, Depression, Nalbuphine
- Trial name
- NCT07009808
- Testing
- Nalbuphine 0.20mg/ml(total 30 mg), Nalbuphine 0.27mg/ml(total 40 mg), Nalbuphine 0.33mg/ml(total 50 mg)
- Volunteers
- 165 people
- Sponsor
- Chengdu Jinjiang Maternity and Child Health Hospital
Pregnancy, Ectopic, Pregnancy, High Risk
Management of Pregnancies of Unknown Location (PUL)
In a randomized multicenter trial the investigators want to compare the ability of two hCG-based models in correctly classifying EPs as high risk among PULs and correctly classifying IUPs and failed PULs as low risk after two hCG…
- Conditions
- Pregnancy, Ectopic, Pregnancy, High Risk, Pregnancy Early
- Trial name
- NCT03461835
- Testing
- Risk classification of PUL by M4, Risk classification of PUL by NICE
- Where
- 3 sites in Sweden
- Volunteers
- 609 people
- Sponsor
- Göteborg University