Clinical trials: Prediabetic State
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
The Effect of Exercise and Nicotinamide Riboside Muscle Health and Insulin Resistance in Survivors of Childhood Cancer
This trial studies the effect of exercise and nicotinamide riboside on muscle health and insulin resistance in adult survivors of childhood cancer with prediabetes (elevated blood sugar level that is not high enough to be…
- Conditions
- Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm, Prediabetes
- Trial name
- NCT05023993
- Testing
- Exercise Intervention, Nicotinamide Riboside
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- City of Hope Medical Center
Prediabetes
Trial of CGM Technology in Persons Living With Prediabetes
Continuous glucose monitor (CGM) technology has become increasingly prevalent in the population and has the ability to transform care of patients living with prediabetes.
- Trial name
- CGM (NCT07639593)
- Testing
- Stelo CGM
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Wake Forest University Health Sciences
MAFLD in Prediabetes and Diabetes
Effect of SGLT2 Inhibitor on Metabolic-Dysfunction-Associated Fatty Liver Disease in Patients With Insulin Resistance
Metabolic-dysfunction-associated fatty liver disease (MAFLD) has evolved as a major health problem recently. Discovering ways to prevent or delay the progression of MAFLD has become a global focus.
- Trial name
- SGLT2 (NCT07891234)
- Testing
- Dapagliflozin 5Mg Tab, Metfomin 500 mg, Dapagliflozin (10mg Tab)
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Sherihan AboElyazed Mohamed Khalil
Pre Diabetic, Obesity & Overweight
The Impact of Continuous Glucose Monitoring on Glucose Variability and Weight Loss in Individuals With Prediabetes and Obesity
This randomized, crossover interventional study evaluates the effects of real-time (open) versus blinded continuous glucose monitoring (CGM) on glycemic variability, lifestyle behaviors, and metabolic outcomes in adults with…
- Trial name
- CGM (NCT07423065)
- Testing
- Continuous Glucose Monitoring (CGM)
- Where
- 3 sites in Slovenia
- Volunteers
- 34 people
- Sponsor
- University of Primorska
Prediabetes
Nested Pilot Study Comparing Two Treatments to Reduce Type 2 Diabetes Risk in At-Risk Delawareans
This nested pilot Randomized Clinical Trial will determine whether the Diabetes Prevention Program (DPP) enhanced with evidence-based sleep health and time restricted eating interventions ("DPP++") is more effective than the DPP…
- Trial name
- NCT07450118
- Testing
- National Diabetes Prevention Program (DPP), Sleep Health Digital Application, Time-Restricted Eating (TRE)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Delaware
Nutritional and Metabolic Diseases, Prediabetes
LIfestyle MEtabotype Study B (LIME-B)
Glycemic responses vary significantly among individuals, even when consuming identical foods or meals, but the factors predicting individual glucose responses to food intake remain poorly investigated.
- Conditions
- Nutritional and Metabolic Diseases, Prediabetes, Type 2 Diabetes
- Trial name
- LIME-B (NCT07888257)
- Testing
- βHB drink (ketone ester), Carbohydrate drink
- Where
- 2 sites in Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- German Institute of Human Nutrition
Prediabetes, Dietary Self-Management
Continuous Glucose Monitoring and Dietary Self-Management in Adults in Namwon
This study will test whether adding a continuous glucose monitoring (CGM) device, which shows personal glucose patterns, improves dietary self-management over the first 6 weeks.
- Conditions
- Prediabetes, Dietary Self-Management, Diabetes Mellitus, Type 2
- Trial name
- NCT07890740
- Testing
- Continuous Glucose Monitoring With Application-Based Biofeedback, Common Standardized Education and Behavioral Goal Setting, Common Digital Health Program and Basic Health Counseling
- Where
- 4 sites in South Korea
- Volunteers
- 860 people
- Sponsor
- Ji-Yeob Choi
Prediabetes, Type 2 Diabetes
New T-UP: Engaging Vulnerable Students in Diabetes Prevention
The goal of this study is to enhance reach and uptake of diabetes prevention among young adults, with a focus on recruiting underserved and high-need students who face additional challenges, including food and financial…
- Trial name
- NCT07225218
- Testing
- Tailored DPP Intervention
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Prediabetes
Efficacy of Diacylglycerol Oil on Metabolic Risk Factors in Prediabetes
This study will implement a four-week dietary intervention among middle-aged and older adults with pre-diabetes. Participants assigned to the intervention arm will replace their usual cooking oil with diacylglycerol (DAG) oil…
- Trial name
- NCT07289880
- Testing
- Diacylglycerol oil, Colza Oil
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangdong Pharmaceutical University
Diabetes Mellitus, Type 2, PreDiabetes
Mastering Diabetes Study
This is a program evaluation that will evaluate the effectiveness of Mastering Diabetes, a therapeutic lifestyle change (TLC) program to control prediabetes and type 2 diabetes.
- Trial name
- NCT04454957
- Testing
- Mastering Diabetes
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Ohio University
PreDiabetes, Adolescent Obesity
SMART GOALS for Youth With Prediabetes
The goal of this study is to compare the impact of a SMART ((specific, measurable, attainable, realistic, or timely) Goal setting protocol on body weight, metabolic parameters (Hemoglobin A1c, lipids), diet quality and physical…
- Conditions
- PreDiabetes, Adolescent Obesity, Behavior, Health, Nutritional and Metabolic Diseases
- Trial name
- NCT06067451
- Testing
- SMART GOALS Setting Tool/ Protocol
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Northwell Health
Type 2 Diabetes, Type II Diabetes Mellitus
The GRoceries Aimed at Increasing Nutrition Study
Only 2% of Americans meet the recommended levels of whole grain consumption, despite its association with reduced risk of type 2 diabetes.
- Conditions
- Type 2 Diabetes, Type II Diabetes Mellitus, Type II Diabetes, Pre-diabetes
- Trial name
- GRAINS (NCT07167004)
- Testing
- Marketing Nudges Only, Marketing Nudges + Dynamically Adapted Financial Incentives
- Where
- United States
- Volunteers
- 219 people
- Sponsor
- University of Pennsylvania
Prediabetes or Overweight, Obesity Type 2 Diabetes Mellitus
Real-World Outcomes of Tirzepatide in Pakistani Adults With Obesity, Prediabetes, and Type 2 Diabetes
This is a multicentre, prospective, observational study of the medicine tirzepatide as it is used in routine clinical care in Pakistan.
- Conditions
- Prediabetes or Overweight, Obesity Type 2 Diabetes Mellitus, Obesity & Overweight
- Trial name
- TRIBUTE-PK (NCT07809568)
- Where
- 9 sites in Pakistan
- Volunteers
- 330 people
- Sponsor
- Universiti Sains Malaysia
Prediabetes, Weight Loss
Diabetes Prevention Through Genetics, Familial History and Behavior Change
The goal of this clinical trial is to learn if adding a family engagement component to the standard Diabetes Prevention Program (DPP) improves outcomes for adults with prediabetes.
- Trial name
- NCT07815236
- Testing
- LEGACY DPP, DPP
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Morehouse School of Medicine
Prediabetic State, Life Style
PreventT2 Together: Examining the Efficacy of Couple-based Lifestyle Intervention to Prevent Type 2 Diabetes
Nearly half of adults in the United States have or are at risk of developing type 2 diabetes. The overall goal of this community-engaged research is to examine the efficacy of an innovative couple-based lifestyle intervention to…
- Conditions
- Prediabetic State, Life Style, Intervention Study, Social Support
- Trial name
- PT2T (NCT06690788)
- Testing
- Individual intervention condition (PreventT2), Couple-based intervention condition (PreventT2 Together; couple-based adaptation of 2021 PreventT2; approved by the CDC in November 2022 as an Alternate Curriculum for use in the NDPP)
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of Utah
Prediabetes
Piloting FUERTE: Federally qUalified Health Centers Engaging Hispanic Men at Risk of diabeTEs
The goal of this study is to learn whether FUERTE (Federally qUalified Health Centers Engaging Hispanic Men at Risk of diabeTEs) can facilitate referrals of Hispanic men with prediabetes to the Diabetes Prevention Program (DPP)…
- Trial name
- FUERTE (NCT07878806)
- Testing
- FUERTE Arm, Standard care, No Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Weill Medical College of Cornell University
Glucose Metabolism Disorders (Including Diabetes Mellitus), Cognitive Decline
Glucose Variability and Cognition in Prediabetes
This study examines the association of variability in glucose values over a 10-day period with cognitive function and AD risk markers among individuals with prediabetes, aged 50 or older.
- Conditions
- Glucose Metabolism Disorders (Including Diabetes Mellitus), Cognitive Decline, PreDiabetes, Aging
- Trial name
- NCT04201600
- Testing
- Continuous Glucose Monitoring System (CGMS)
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Type 2 Diabetes, Insulin Resistance
Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents
This research study collects health-related information and blood samples to better understand how body composition, lifestyle habits, and diet influence meta-inflammatory monocytes (MiMos) in adolescents.
- Conditions
- Type 2 Diabetes, Insulin Resistance, Obesity, Metabolic Disease
- Trial name
- NCT06007404
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Obesity, Gestational Diabetes
Strategies for Implementing a Postpartum Lifestyle Intervention in WIC Clinics
The primary objective of the STRIVE study is to compare two implementation strategies for Diabetes Prevention Program delivery: an in-person health coach strategy (standard 24 in-person sessions at WIC clinics) vs.
- Conditions
- Obesity, Gestational Diabetes, Lifestyle, Healthy, Glucose Intolerance During Pregnancy
- Trial name
- STRIVE (NCT06116149)
- Testing
- In-person health coach delivery of the GLB, Technology-assisted health coach delivery of the GLB
- Where
- United States
- Volunteers
- 722 people, healthy volunteers welcome
- Sponsor
- Tulane University
Diabetes, PreDiabetes
Fresh Takes!: An Evaluation of the Impact of Receiving Fresh Food Boxes
Fresh Takes! is a targeted food distribution and nutrition education program offered by Montefiore Bronx Health Collective, a Federally Qualified Health Center located in the South Bronx.
- Conditions
- Diabetes, PreDiabetes, Food Insecurity
- Trial name
- NCT06019624
- Testing
- Fresh Takes!
- Where
- United States
- Volunteers
- 315 people
- Sponsor
- Montefiore Medical Center