Clinical trials: Pre-Frailty
Frail Elderly Syndrome
A Health Promotion Program to Prevent Frailty and Improve Frailty Status Among Pre-frail Elderly: Frailty Intervention Through Nutrition Education and Exercises.
Prevention of frailty is a major concern in geriatrics due to its high prevalence and various adverse health outcomes among elderly population.
- Trial name
- FINE (NCT04327544)
- Testing
- Frailty Intervention
- Where
- Malaysia
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Frailty
Blood Flow Restriction on Functional Mobility in Pre-frail Older Adults
This study investigates the effect of blood flow restriction with resistance exercise on functional mobility in pre-frail older adults.
- Trial name
- NCT05209685
- Testing
- Resistance exercise on the lower extremities, Resistance exercise on the lower extremities with blood flow restriction
- Where
- Taiwan
- Volunteers
- 54 people
- Sponsor
- National Cheng Kung University
Frailty, Quality of Life
Frailty Status and Quality of Life in Elderly
Frailty is a dynamic process from fit (robust) and pre-frail elderly. There is no previous study that determine the risk factors from fit to pre-frailty and pre-frailty to frailty in Indonesian elderly.
- Trial name
- NCT02333552
- Volunteers
- 269 people
- Sponsor
- Universitas Indonesia
Pre-frail Elderly
The Effect of SOD Enzyme on Frailty and HRQOL Among Indonesian Pre-frail Elderly: A Double Blind Randomized Controlled Trial
The primary objective is to determine the effect of SOD enzyme on frailty and health related quality of life among Indonesian pre-frail elderly.
- Trial name
- NCT02753582
- Testing
- SOD+Gliadin Capsule
- Where
- Indonesia
- Volunteers
- 150 people
- Sponsor
- Universitas Indonesia
Aortic Aneurysm, Abdominal
Adherence and Acceptability of a Remote, Home-based, Pre-surgery Programme for Patients Undergoing Abdominal Aortic Aneurysm Surgery
Design A multi-centre pilot study investigating the acceptability and adherence of a prehabilitation on patients requiring abdominal aortic aneurysm repair. Setting 3 NHS Hospital Vascular Surgery Clinics in the UK.
- Trial name
- NCT04792411
- Testing
- Prehabilitation
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Frailty, Dementia
HEalthy Aging Team Supported Home-care Services (HEAT-YASAM)
Depending on the YASAM project which was established to home-visit evaluate community-dwelling older adults (80 years of age and over), we aimed to determine the prevalence (prevalence) of geriatric syndromes (dependence…
- Conditions
- Frailty, Dementia, Depression, Malnutrition
- Trial name
- HEAT-YASAM (NCT05993572)
- Testing
- Comprehensive Geriatric Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Gulhane Training and Research Hospital
Spine Degeneration, Spine Fusion
Pre-operative Risk Assessment Combined With Targeted Intervention in the Chinese Elderly With Spine Surgery
With the extended life expectancy of the Chinese population and improvements in surgery and anesthesia techniques, the number of aged patients undergoing surgery has been increasing annually.
- Conditions
- Spine Degeneration, Spine Fusion, Frailty Syndrome
- Trial name
- PRACTICE (NCT06140797)
- Testing
- Multimodal prehabilitation combined with perioperative ERAS care（PREERAS）
- Where
- 3 sites in China
- Volunteers
- 164 people
- Sponsor
- Xuanwu Hospital, Beijing
Fragility
Investigation of a Link Between Heart Rate Variability and Frailty in Geriatric Patients
The aim of this study is the evaluation of differences in heart rate variability (both time- and frequency-domain) [a]: between frail and non-frail patients and [b] at the beginning and end of a geriatric therapy which included…
- Trial name
- NCT03585985
- Testing
- Standard patient monitor, Photoplethysmographie-Imaging (PPGI) + Infrared thermography (IRT)
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Frailty Syndrome, Surgery--Complications
Pre-frailty and Rehospitalization in Cardiac Surgery
Background: It has been demonstrated that pre-frailty has more adverse outcomes after cardiac surgery, however, data on prognosis and long-term evolution in pre-frailty patients after cardiac surgery without postoperative…
- Conditions
- Frailty Syndrome, Surgery--Complications, Coronary Artery Disease, Valve Anomalies
- Trial name
- NCT03949439
- Testing
- Elective Cardiac Surgery
- Where
- Brazil
- Volunteers
- 453 people
- Sponsor
- Instituto Dante Pazzanese de Cardiologia
Frailty
Evaluation of a Frailty Intervention Program in Hong Kong
The present study aims to compare the pre-post effect of a frailty intervention program with exercise, nutrition, cognitive and social components with a control group without such program on improving gait speed and frailty in…
- Trial name
- NCT04216056
- Testing
- Frailty intervention program
- Where
- China
- Volunteers
- 185 people
- Sponsor
- Chinese University of Hong Kong
Frailty, Frail Elderly
Prehabilitation of Elderly Patients With Frailty Syndrome Before Elective Surgery (PRAEP-GO)
The aim of the study is to evaluate the effect of a shared decision-making conference and three-week prehabilitation program on the outcome "care dependency" one year after surgery.
- Trial name
- NCT04418271
- Testing
- Prehabilitation- new form of care
- Where
- 23 sites in Germany
- Volunteers
- 1,199 people
- Sponsor
- Charite University, Berlin, Germany
Stroke, Frailty
Pilot of Cognitive Stimulation Therapy for Pre-frail Stroke Survivors
Frailty is described as a type of vulnerability where one can struggle to recover fully from things that can put stress on one\'s body, e.g., cold weather or bronchitis.
- Conditions
- Stroke, Frailty, Carers
- Trial name
- NCT06733103
- Testing
- Stroke Cognitive Behavioural Therapy
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Chronic Kidney Diseases
Description of Treatment Patterns and Population Characteristics of Pre-dialysis CKD Patients in the Czech Republic
The decision making in the Czech nephrology offices depends on the local common practice which is likely to be heterogenous. In other words, the same patient would be indicated to different therapy and regimen at different sites.
- Trial name
- NCT05380843
- Where
- 5 sites in Czechia
- Volunteers
- 1,200 people
- Sponsor
- Value Outcomes Ltd.
Lung Cancer, Esophageal Cancer
Assessment of Patient Frailty Prior to Thoracic Surgery
Determine the feasibility of assessment of measures of frailty and determine if these measures provide a clinically important contribution of risk assessment in a population of patients undergoing major thoracic surgery for lung…
- Trial name
- NCT02803281
- Testing
- Frailty Assessment
- Where
- 3 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Pre-Frailty, Aging
Exploratory Study on a Multi-nutrient Supplement and Exercise Program for Improving Health Markers Associated to Longevity in Pre-frail Adults
Frailty is associated with biological changes in the gut microbiome and immune system, along with marked declines in physical and cognitive function, leading to an overall reduction in quality of life.
- Trial name
- RtM (NCT07454616)
- Testing
- Supervised exercise program, a balanced micronutrient blend
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- National University of Singapore
Pre-frail
Effects of Whole Body Vibration in Pre-frail Individuals Over 65 Years of Age
In this study, individuals aged 65 and over who applied to the physical medicine and rehabilitation outpatient clinic with any complaint will be evaluated in terms of geriatric syndromes.
- Trial name
- NCT06004999
- Testing
- Whole body vibration, The exercise program on flat ground without a vibration platform
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Trakya University
Sarcopenia
Exercise and Nutrition for Healthy AgeiNg
The aim of this randomized placebo-controlled 5-arm clinical trial is to evaluate the effect of combined anabolic interventions compared to single or placebo interventions on physical performance in community-dwelling…
- Trial name
- ENHANce (NCT03649698)
- Testing
- Home-based training program, High-quality protein supplement, Omega-3 fatty acid
- Where
- Belgium
- Volunteers
- 180 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Older Adults
The Effectiveness of Health Promotion Programs on the Pre-frail Individuals
This pilot study aimed to examine the efficacy of a home-based multicomponent exercise training program in older community- dwellers during to the Coronavirus Disease 2019.
- Trial name
- NCT05476471
- Testing
- multicomponent exercise training program
- Where
- Taiwan
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Shu-Hung Chang
Fragility, Sarcopenia
Efficacy of an Intervention to Prevent Frailty in Obese Elderly People (PRE-FROB)
Rationale: There is increasing evidence that obesity may be a risk factor for frailty in the elderly. Obesity favors a state of chronic inflammation and insulin resistance, involves a fatty infiltration of the muscle and an…
- Conditions
- Fragility, Sarcopenia, Obese, Elderly
- Trial name
- PRE-FROB (NCT03000907)
- Testing
- Intervention
- Where
- Spain
- Volunteers
- 319 people
- Sponsor
- Consorci Sanitari del Maresme
Post Cardiac Surgery
Pre-Frailty Risk in Cardiovascular Surgery
Frailty is an important risk factor for cardiovascular disease (CVD), recent data has shown significant association between pre-frailty and the risk of incident for CVD, irrespective of any classical cardiometabolic risk factors…
- Trial name
- NCT02829203
- Volunteers
- 221 people
- Sponsor
- Instituto Dante Pazzanese de Cardiologia