Clinical trials: Practice Guideline
Relapsed and Refractory Multiple Myeloma
Retrospective Viability Study of the PETHEMA-POMCIDEX Clinical Practice Guidelines for the Treatment of Patients With Relapsed and Refractory Multiple Myeloma (RRMM)
Multiple myeloma (MM) is a plasma cell neoplasm representing the second most common type of hematologic tumor after lymphomas. The incorporation of novel agents such as bortezomib, lenalidomide, or thalidomide into first-line…
- Trial name
- NCT03477643
- Where
- 27 sites in Spain
- Volunteers
- 110 people
- Sponsor
- PETHEMA Foundation
Nutritional Support, Intensive Care Unit
Evaluation of Nutritional Practices in the Critical Care
Background: The adequacy of the artificial Nutritional Support (NS) in the critical care patient has implications in morbidity and prognosis.
- Conditions
- Nutritional Support, Intensive Care Unit, Critical Illness
- Trial name
- ENPIC (NCT03634943)
- Testing
- Patients with Nutritional Support
- Where
- 43 sites in Spain
- Volunteers
- 642 people
- Sponsor
- Hospital Universitari de Bellvitge
Amblyopia, Strabismus
Multimodal Physician Intervention to Detect Amblyopia
Current research shows low rates of quantitative vision screening at preschool ages in the medical home. This study targets providers (PCPs) to evaluate the effectiveness of a web-based intervention to improve knowledge about…
- Trial name
- EPPICC (NCT01109459)
- Testing
- Pediatric blood pressure screening, Pediatric vision screening
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- University of Alabama at Birmingham
Diverticulitis
Improving the Treatment of Acute Uncomplicated Diverticulitis in Routine Care
Acute uncomplicated diverticulitis is often treated with antibiotics, although current evidence shows that antibiotics are not always necessary.
- Trial name
- AUD (NCT07824180)
- Testing
- standardized treatment algorithm
- Volunteers
- 800 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Clinical Decision Support, Clinical Practice Guidelines
Professional Development in Emergency Medical Services
The ProDEms-trial focuses on nurses and ambulance drivers working in prehospital care, taking care on the one hand of patients suffering from time-sensitive critical conditions like STEMI, acute stroke or severe traumatic brain…
- Conditions
- Clinical Decision Support, Clinical Practice Guidelines, Emergency Medical Services
- Trial name
- ProDEms (NCT02365792)
- Testing
- Clinical Decision Support Tool for Prehospital Care
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- KU Leuven
Overweight, Obesity
Network Meta-analyses of Artificially Sweetened Beverages and Cardiometabolic Risk
Sugars especially in form or sugar-sweetened beverages (SSBs) have been singled out as one of the prime culprits in the dual epidemics of obesity and diabetes.
- Trial name
- NCT02879500
- Testing
- Diet beverages
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Malaria
Use of Rapid Diagnostic Tests for Malaria Case Management in Kenya
The purpose of this study is to investigate the impact of rapid diagnostic tests (RDTs) in the context of a newly implemented malaria case management guidelines using artemisinin-based combination therapy on the malaria…
- Trial name
- NCT00336388
- Testing
- Paracheck Device
- Where
- Kenya
- Volunteers
- 3,600 people
- Sponsor
- Centers for Disease Control and Prevention
Peripheral Arterial Disease
Prevention of Ischemic Events in Patients With Peripheral Arterial Disease
The PID-PAB study aims to test the efficacy of the European Guidelines on Cardiovascular Disease Prevention in patients with peripheral arterial disease.
- Trial name
- PID-PAB (NCT00761969)
- Testing
- Implementation of the European Guidelines on cardiovascular Disease Prevention in Clinical Practice
- Where
- Slovenia
- Volunteers
- 1,455 people, healthy volunteers welcome
- Sponsor
- KRKA
Chronic Kidney Disease, Chronic Kidney Insufficiency
Improving Evidence-Based Primary Care for Chronic Kidney Disease
Background: Chronic Kidney Disease (CKD) is under-recognized and under-treated in primary care offices and primary care physicians are generally not familiar with treatment guidelines.
- Conditions
- Chronic Kidney Disease, Chronic Kidney Insufficiency, Chronic Renal Diseases, Chronic Renal Insufficiency
- Trial name
- NCT01767883
- Testing
- Facilitated Clinical Decision Support, Clinical Decision Support Only
- Where
- United States
- Volunteers
- 27,000 people
- Sponsor
- American Academy of Family Physicians
Hypertension
Group Visits to Improve Hypertension Management
This study investigates group medical visits as a quality improvement strategy for hypertension. It studies group visits in which patients see their own primary care provider together with other patients who have hypertension.
- Trial name
- NCT00129493
- Testing
- Group medical visits
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- US Department of Veterans Affairs
Diabetes Mellitus, Cardiovascular Disease
Evaluation of a Toolkit to Improve Cardiovascular Disease Screening and Treatment for People With Type 2 Diabetes
Diabetes is a common and serious chronic disease. However, there is a large gap between the level of care that people should receive (based on research and guidelines) and the level of care they actually receive.
- Trial name
- NCT01026688
- Testing
- Toolkit, Control
- Where
- Canada
- Volunteers
- 1,592 people
- Sponsor
- Sunnybrook Health Sciences Centre
Colorectal Cancer
Translation of Colorectal Cancer Screening Guidelines to Practice: A System Intervention
Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the United States. Results from randomized clinical trials and intervention studies have suggested that implementation of a CRC screening program for…
- Trial name
- NCT00122187
- Testing
- Electronic Consult System
- Where
- 9 sites in United States
- Volunteers
- 8 people
- Sponsor
- US Department of Veterans Affairs
Hypertension
VISN Collaborative for Improving Hypertension Management With ATHENA-HTN
This project is a VA HSR\&D-funded Quality Enhancement Research Initiative (QUERI) project to translate into practice evidence about clinical management of primary hypertension.
- Trial name
- HTN (NCT00374452)
- Testing
- ATHENA-CDS-HTN plus Guideline Link, Guideline Link Only
- Where
- 7 sites in United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Evidence Based Practice, Stroke
Adherence to Stroke Rehabilitation Guidelines Among Physical Therapists and Internship Students
The goal of this observational study is to learn about adherence to the 2024 VA/DoD Clinical Practice Guidelines for Stroke Rehabilitation among Turkish physiotherapists and internship students treating post-stroke patients.
- Conditions
- Evidence Based Practice, Stroke, Physical Therapist
- Trial name
- NCT07044817
- Testing
- Stroke Rehabilitation Guideline Adherence Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Medipol University
Contraception
A Prospective Observational Study of the Clinical Performance of Femplant in Pakistan
This will be a non-comparative prospective observational study of women using Femplant as a primary method of contraception in Pakistan.
- Trial name
- NCT01463254
- Where
- Pakistan
- Volunteers
- 724 people, healthy volunteers welcome
- Sponsor
- FHI 360
HIV Infections, Gonorrhea
Cellulose Sulfate (CS) Gel and HIV in Nigeria
This is a Phase 3, multi-center, randomized, placebo-controlled trial to determine the effectiveness and safety of the 6% cellulose sulfate (CS) vaginal gel for the prevention of HIV infection.
- Conditions
- HIV Infections, Gonorrhea, Chlamydia Infections
- Trial name
- NCT00120770
- Testing
- Cellulose Sulfate Vaginal Gel (Microbicide)
- Where
- 2 sites in Nigeria
- Volunteers
- 2,160 people, healthy volunteers welcome
- Sponsor
- FHI 360
Fluid Therapy
Fluid Day Spanish Observational Study
Perioperative fluid therapy has undergone a huge change in clinical practice in recent years. The patterns of replacement and / or restoration of volemia described in the classic anaesthesiology books were supported by weak…
- Trial name
- Fluid Day (NCT03630744)
- Testing
- Fluid therapy
- Where
- Spain
- Volunteers
- 3,500 people
- Sponsor
- Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor
Attitude, Practice Guideline
Patient Perception of Mammogram Guidelines
The purpose of this study was to determine attitudes regarding the 2009 USPSTF Guidelines for breast cancer screening for women in their 40's and assess the effect of one of two newspaper articles on their attitudes.
- Conditions
- Attitude, Practice Guideline, Breast Cancer
- Trial name
- NCT01267877
- Testing
- read unfavorable article prior to answering questions, read favorable article prior to answering questions
- Where
- 4 sites in United States
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Diabetes, Prediabetes
Meta-analyses of Pasta as Part of Low Glycemic Index Diets and Adiposity
Pasta is an important example of a food which can lower the glycemic index (GI) of the diet, a property that has been exploited extensively in studies of low GI dietary patterns.
- Conditions
- Diabetes, Prediabetes, Overweight, Obesity
- Trial name
- NCT02961088
- Testing
- Pasta as part of a low GI/GL diet
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Chronic Obstructive Pulmonary Disease (COPD)
Translating The GOLD COPD Guidelines Into Primary Care Practice
This project will evaluate the translation of the Gold (the Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease) COPD guidelines into primary care practice.
- Trial name
- LungAge (NCT01237561)
- Testing
- provider support tools plus spirometer
- Where
- United States
- Volunteers
- 3,593 people, healthy volunteers welcome
- Sponsor
- Memorial Hospital of Rhode Island