Clinical trials: Postspinal Hypotension
Adverse Effect
Phenylephrine Prophylaxis for Postspinal Anesthesia Hypotension in Parturients With Preeclampsia
The purpose of this study is to investigate the suitable infusion dose of phenylephrine for prophylaxis against postspinal anesthesia hypotension in parturients with preeclampsia undergoing cesarean section.
- Trial name
- NCT04576663
- Testing
- Normal saline, Phenylephrine
- Volunteers
- 95 people
- Sponsor
- General Hospital of Ningxia Medical University
Postspinal Hypotension, Cesarean Birth
The Role of Preoperative Internal Jugular Vein Collapsibility and Perfusion Index in Predicting Hypotension After Spinal Anesthesia in Elective Cesarean Sections: A Prospective Observational Study
Spinal anesthesia is widely preferred for elective cesarean delivery due to its favorable safety profile and superior postoperative analgesia.
- Trial name
- NCT07539896
- Testing
- Baseline PI will be recorded,IJV diameters will be measured via ultrasound
- Volunteers
- 110 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Adverse Effect
Norepinephrine Prophylaxis for Postspinal Anesthesia Hypotension
The purpose of this study is to investigate the suitable infusion dose of norepinephrine for prophylaxis against post-spinal anesthesia hypotension.
- Trial name
- NCT04272567
- Testing
- Norepinephrine, Normal saline
- Where
- China
- Volunteers
- 99 people
- Sponsor
- General Hospital of Ningxia Medical University
Comparing Ephedrine With Norepinephrine for Mangement Postspinal Hypotension
Effectiveness of Prophylactic Bolus Ephedrine Versus Norepinephrine for Management of Post Spinal Hypotension
This study was conducted to compare the effectiveness of ephedrine versus norepinephrine for management of hypotension after spinal anesthesia for mothers undergoing elective cesarean section
- Trial name
- NCT05522088
- Where
- Ethiopia
- Volunteers
- 84 people
- Sponsor
- Wachemo University
Complications; Anesthesia, Spinal and Epidural, in Pregnancy
The Effect of the Timing of Colloid and Crystalloid Infusions on Postspinal Hypotension After Spinal Anesthesia for Caesarian Section
Prevention of postspinal hypotension after spinal anesthesia for caesarian section by use of preoperative or intraoperative volume replacement.
- Trial name
- NCT02680678
- Testing
- Colloid Preload, colloid co-load, Crystalloid preload
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Adverse Effect
90% Effective Dose of Phenylephrine Infusions Under Intensive and Standard Treatment
The objective of this study is to investigate the 90% effective dose of phenylephrine infusions for preventing postspinal anesthesia hypotension under intensive and standard treatment during cesarean section
- Trial name
- NCT06151522
- Testing
- Alpha-Agonist, α-adrenergic receptor agonist
- Volunteers
- 80 people
- Sponsor
- General Hospital of Ningxia Medical University
Adverse Event
Prophylactic Norepinephrine Infusion Combined With Colloid Coloading for Postspinal Anesthesia Hypotension
The purpose of this study is to investigate the suitable infusion dose of prophylactic norepinephrine infusion combined with 6% Hydroxyethyl starch (130/0.4) coload for post-spinal anesthesia hypotension in patients undergoing…
- Trial name
- NCT05133817
- Testing
- Normal saline, Norepinephrine (0.025 μg/kg/min), Norepinephrine (0.05 μg/kg/min)
- Where
- China
- Volunteers
- 175 people
- Sponsor
- General Hospital of Ningxia Medical University
Adverse Effect
Comparison of Different HES Coload Volumes on the 90% ED of Norepinephrine
The purpose of this study is to investigate the effect of different 6% hydroxyethyl starch (130/0.4) coload volumes on the 90% effective dose of norepinephrine infusion prophylaxis for hypotension during spinal anesthesia for…
- Trial name
- NCT05712018
- Testing
- Hydroxyethyl starch coload - 0 ml/kg, Hydroxyethyl starch coload - 5 ml/kg, Hydroxyethyl starch coload - 10 ml/kg
- Where
- China
- Volunteers
- 90 people
- Sponsor
- General Hospital of Ningxia Medical University
Postspinal Hypotension
Diastolic Shock Index for Predicting Postspinal Hypotension
This prospective observational study aims to evaluate the diagnostic performance of the preoperative Diastolic Shock Index in predicting postspinal hypotension and to compare its performance with other shock indices, including…
- Trial name
- NCT07765342
- Testing
- Spinal Anesthesia
- Volunteers
- 85 people
- Sponsor
- Istinye University
Adverse Effect
90% Effective Dose of Phenylephrine Infusions Under Intensive and Standard Treatment in Preeclamptic Patients
The objective of this study is to investigate the 90% effective dose of phenylephrine infusions for preventing postspinal anesthesia hypotension under intensive and standard treatment in preeclamptic patients during cesarean…
- Trial name
- NCT06151470
- Testing
- Alpha-Agonist, α-adrenergic receptor agonist
- Volunteers
- 80 people
- Sponsor
- General Hospital of Ningxia Medical University
Hypotension Symptomatic, Vasoconstriction
Colloid Co-hydration and Vasoconstrictor Infusion for Prevention of Hypotension During Cesarean Section
This will be a double-blind randomized study, aiming at investigating a fixed rate phenylephrine infusion versus a fixed rate norepinephrine infusion versus placebo in combination with co-hydration with colloids for the…
- Conditions
- Hypotension Symptomatic, Vasoconstriction, Cesarean Section Complications, Obstetric Anesthesia Problems
- Trial name
- annie-zoe (NCT04404946)
- Testing
- phenylephrine infusion, norepinephrine infusion
- Where
- Greece
- Volunteers
- 120 people
- Sponsor
- Aretaieion University Hospital
Adverse Effect
Different Crystalloid Coload Volumes on the 90% ED of Norepinephrine
The purpose of this study is to investigate the effect of different crystalloid coload volumes on the 90% effective dose of prophylactic norepinephrine infusions for preventing postspinal anesthesia hypotension during cesarean…
- Trial name
- NCT05690334
- Testing
- Crystalloid - 0 ml/kg, Crystalloid - 5 ml/kg, Crystalloid - 10 ml/kg
- Where
- China
- Volunteers
- 90 people
- Sponsor
- General Hospital of Ningxia Medical University
Adverse Effect
90% Effective Dose of Norepinephrine Infusions Under Intensive and Standard Treatment
The objective of this study is to investigate the 90% effective dose of norepinephrine infusions for preventing postspinal anesthesia hypotension under intensive and standard treatment during cesarean section
- Trial name
- NCT06151509
- Testing
- Alpha-Agonist, α-adrenergic receptor agonist
- Volunteers
- 80 people
- Sponsor
- General Hospital of Ningxia Medical University
Postspinal Hypotension, Cesarean Delivery
Two Norepinephrine Rescue Bolus Doses for Management of Severe Post-spinal Hypotension During Elective Cesarean Delivery
Maternal hypotension after spinal block is a common complication after subarachnoid block in this population whose incidence reached 60% in many reports.
- Conditions
- Postspinal Hypotension, Cesarean Delivery, Norepinephrine
- Trial name
- NCT05290740
- Testing
- Norepinephrine 5 mcg, Norepinephrine 10 mcg
- Where
- Egypt
- Volunteers
- 158 people
- Sponsor
- Kasr El Aini Hospital
Adverse Effect
Prophylactic Norepinephrine and Phenylephrine Boluses for Postspinal Anesthesia Hypotension
The purpose of this study is to investigate the potency between prophylactic norepinephrine and phenylephrine boluses for postspinal anesthesia hypotension in patients undergoing caesarean section.
- Trial name
- NCT05035888
- Testing
- Phenylephrine, Norepinephrine
- Where
- China
- Volunteers
- 80 people
- Sponsor
- General Hospital of Ningxia Medical University
Adverse Effect
ED90 of Norepinephrine and Phenylephrine Infusions Under Intensive Treatment
The objective of this study is to investigate the ED90 of norepinephrine and phenylephrine infusions for preventing postspinal anesthesia hypotension under intensive treatment during cesarean section
- Trial name
- NCT06158048
- Testing
- Norepinephrine, Phenylephrine
- Where
- China
- Volunteers
- 60 people
- Sponsor
- General Hospital of Ningxia Medical University
Adverse Effect
Norepinephrine Prophylaxis for Postspinal Anesthesia Hypotension in Parturients With Preeclampsia.
The purpose of this study is to investigate the suitable infusion dose of norepinephrine for prophylaxis against postspinal anesthesia hypotension in parturients with preeclampsia undergoing cesarean section.
- Trial name
- NCT04556370
- Testing
- Normal saline, Norepinephrine
- Where
- China
- Volunteers
- 180 people
- Sponsor
- General Hospital of Ningxia Medical University
Adverse Effect
Comparison of Hydroxyethyl Starch and Crystalloid Coload Combined With Norepinephrine Infusion for Hypotension
The purpose of this study is to investigate the ED50 and ED90 for an effective 6% Hydroxyethyl starch (130/0.4) or crystalloid coload combined with prophylactic norepinephrine infusion dose for postspinal anesthesia hypotension…
- Trial name
- NCT05475990
- Testing
- Hydroxyethyl starch, Crystalloid
- Where
- China
- Volunteers
- 80 people
- Sponsor
- General Hospital of Ningxia Medical University
Anesthesia Complication, Vasopressor
Management of Postspinal Anesthesia Hypotension During Elective Cesarean Section: Baby Norepinephrine Versus Ephedrine
Background : Spinal anesthesia emerges as the preferred anesthesia technique for elective cesarean section . It offers a preferable alternative to general anesthesia because it provides better maternal safety and neonatal…
- Conditions
- Anesthesia Complication, Vasopressor, Cesarean Section Complications, Hypotension During Surgery
- Trial name
- NCT06498076
- Testing
- Norepinephrine, Ephedrine
- Where
- Tunisia
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Hopital Charles Nicolle
Adverse Effect
The Potency of Prophylactic Norepinephrine and Phenylephrine Boluses for Postspinal Anesthesia Hypotension
The purpose of this study is to investigate the potency between prophylactic norepinephrine and phenylephrine boluses for postspinal anesthesia hypotension in patients with severe preeclampsia during caesarean section.
- Trial name
- NCT05035472
- Testing
- Phenylephrine, Norepinephrine
- Volunteers
- 80 people
- Sponsor
- General Hospital of Ningxia Medical University