Clinical trials: Postoperative Pulmonary Complications (PPCs)
Postoperative Pulmonary Complications (PPCs), Feasibility Studies
PROtective Ventilation With FLOW-Controlled Ventilation
The investigators want to investigate in patients undergoing robot-assisted laparoscopic surgery (a minimally invasive procedure) how applicable flow-controlled ventilation is, and whether it might also be safer than the current…
- Conditions
- Postoperative Pulmonary Complications (PPCs), Feasibility Studies, Pilot Study
- Trial name
- PROFLOW (NCT06703814)
- Testing
- Intraoperative flow-controlled ventilation strategy, Intraoperative pressure-controlled ventilation strategy
- Where
- 3 sites in Austria, Germany and 1 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cantonal Hospital of St. Gallen
Mechanical Ventilation, Postoperative Pulmonary Complications (PPCs)
Flow-Controlled Ventilation to Improve Postoperative Pulmonary Outcome After Thoracic Surgery
In an international multicenter randomized clinical pilot trial, intraoperative flow-controlled ventilation (FCV) will be compared with volume-controlled ventilation (VCV) in patients scheduled for (open, video- or…
- Trial name
- PROFLOW-THORAC (NCT07623395)
- Testing
- Flow-Controlled Ventilation, Volume-Controlled Ventilation
- Where
- 7 sites in Austria, France and 2 more
- Volunteers
- 140 people
- Sponsor
- Cantonal Hospital of St. Gallen
Mechanical Ventilation, Postoperative Pulmonary Complications (PPCs)
Intraoperative Driving Pressure and Postoperative Lung Ultrasound Score in Robot-Assisted Radical Prostatectomy
The primary objective of this study is to evaluate the relationship between intraoperative driving pressure and postoperative lung ultrasound scores in patients undergoing robot-assisted laparoscopic radical prostatectomy.
- Conditions
- Mechanical Ventilation, Postoperative Pulmonary Complications (PPCs), Prostatic Neoplams, Driving Pressure
- Trial name
- NCT07610824
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara Etlik City Hospital
Postoperative Pulmonary Complications (PPCs), Preoperative Functional Status
Physical Function Before Surgery and Lung Complications After Lung Surgery
This study will examine whether patients' ability to perform everyday physical activities before lung surgery is related to their risk of developing lung complications after surgery.
- Trial name
- NCT07853430
- Testing
- Preoperative Functional Status Assessment
- Volunteers
- 450 people
- Sponsor
- Aerospace Center Hospital
Postoperative Pulmonary Complications (PPCs), Atelectasis
Evaluation of the Effectiveness of Lung-Protective Ventilation in Patients Undergoing Laparoscopic Gastrectomy
The goal of this clinical trial is to learn if lung-protective ventilation can improve perioperative oxygenation and reduce postoperative pulmonary complications in patients undergoing elective laparoscopic gastrectomy.
- Trial name
- NCT07823816
- Testing
- Conventional Ventilation, Lung-Protective Ventilation
- Where
- Vietnam
- Volunteers
- 102 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
CABG, Respiratory Insufficiency
Early Postoperative Physiotherapy to Prevent Respiratory Insufficiency After Elective Heart Surgery
This study aims to determine whether starting respiratory physiotherapy one hour after removal of the breathing tube following elective coronary artery bypass graft (CABG) surgery leads to better recovery than the current…
- Conditions
- CABG, Respiratory Insufficiency, Postoperative Pulmonary Complications (PPCs)
- Trial name
- EPP-CABG (NCT07730034)
- Testing
- Early postoperative physiotherapy, Standard postoperative care
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- Dijana Filipović
Intraoperative Hypotension, Postoperative Pulmonary Complications (PPCs)
PRO STRESS Trial: Proactive Low-Dose Norepinephrine to Reduce Intraoperative Fluid Administration in Patients at High-Risk for Postoperative Pulmonary Complications Undergoing Laparoscopic Abdominal Surgery
Intraoperative hypotension is commonly treated with fluid administration; however, excessive fluid therapy may contribute to postoperative pulmonary complications.
- Conditions
- Intraoperative Hypotension, Postoperative Pulmonary Complications (PPCs), Fluid Over-load
- Trial name
- PRO STRESS (NCT07627360)
- Testing
- Norepinephrine
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Suez Canal University
Esophageal Cancer (EsC), Postoperative Pulmonary Complications (PPCs)
Effect of VExUS Score on Postoperative Pulmonary Complications in Elderly Patients
Brief Summary This clinical trial aims to evaluate whether perioperative goal-directed fluid therapy (GDFT) targeting a venous excess ultrasound (VExUS) score of 1 can reduce postoperative pulmonary complications (PPCs) in…
- Trial name
- NCT07691944
- Testing
- VExUS Score-Guided Intraoperative Goal-Directed Fluid Therapy
- Volunteers
- 126 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Robotic Surgery, Urologic Surgical Procedures
Timing of Recruitment Maneuver in Robotic Prostate Surgery
Robotic prostate surgery is commonly performed under general anesthesia with carbon dioxide pneumoperitoneum and steep Trendelenburg positioning.
- Conditions
- Robotic Surgery, Urologic Surgical Procedures, Postoperative Pulmonary Complications (PPCs), Pulmonary Atelectasis
- Trial name
- ROBPROREC1 (NCT07662642)
- Testing
- Recruitment maneuver after insufflation and Trendelenburg positioning, Recruitment maneuver in the supine position
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Ankara University
Lung Neoplasm, Lung Cancer
Lung Ultrasound to Assess Aeration Loss After Lung Resection Surgery
The purpose of this prospective observational study is to assess perioperative changes in lung aeration after lung resection surgery using lung ultrasound, and to explore their relationship with oxygenation, inflammatory…
- Conditions
- Lung Neoplasm, Lung Cancer, Lung Resection Surgery, Thoracic Surgery
- Trial name
- THORUS (NCT04677309)
- Testing
- Perioperative lung ultrasound assessment
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Ana Broseta Lleó
Cardiac Surgery, Mechanical Power
Individualized PEEP and Pulmonary Complications in On-Pump CABG
Postoperative pulmonary complications (PPCs) are an important cause of morbidity and mortality after major surgery and are frequently observed in cardiac surgery patients undergoing cardiopulmonary bypass (CPB).
- Conditions
- Cardiac Surgery, Mechanical Power, Postoperative Pulmonary Complications (PPCs)
- Trial name
- NCT07623109
- Testing
- Driving pressure-based personalized PEEP strategy, Conventional lung protective mechanical ventilation strategy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bursa City Hospital
Postoperative Pulmonary Complications (PPCs), Cardiac Surgery With Sternotomy
Effect of Positioning and ACBT on Pulmonary Complications After Cardiac Surgery
The goal of this quasi-experimental clinical trial is to learn if position management combined with the Active Cycle of Breathing Techniques (ACBT) works to reduce postoperative pulmonary complications in adult patients…
- Conditions
- Postoperative Pulmonary Complications (PPCs), Cardiac Surgery With Sternotomy, Atelectasis, Postoperative Pneumonia
- Trial name
- P-ACBT (NCT07612033)
- Testing
- Structured Position Management Protocol, Active Cycle of Breathing Techniques (ACBT)
- Where
- Egypt
- Volunteers
- 124 people
- Sponsor
- Assiut University
Postoperative Pulmonary Complications (PPCs)
Postoperative High-flow Nasal Oxygenation After High-risk Surgery in the Frail Adult
High flow nasal oxygen (HFNO) in the immediate postoperative period has been demonstrated to reduce the risk of postoperative pulmonary complications (PPC) after cardiothoracic surgery.
- Trial name
- Hi-POP (NCT07464730)
- Testing
- High Flow Oxygen, Oxygen
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Region Stockholm
Postoperative Pulmonary Complications (PPCs), Abdominal Surgeries
Can Ultrasound-Guided Fascial Plane Blocks Reduce Postoperative Pulmonary Complications After Major Abdominal Surgery?
This prospective observational study aims to evaluate whether the use of ultrasound-guided fascial plane blocks is associated with a lower incidence of postoperative pulmonary complications in adult patients undergoing elective…
- Conditions
- Postoperative Pulmonary Complications (PPCs), Abdominal Surgeries, Postoperative Pain Management
- Trial name
- FPB-PPC (NCT07394816)
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Mechanical Power, Postoperative Pulmonary Complications (PPCs)
EIT vs Dynamic Compliance Guided PEEP Titration During Laparoscopic Gynecological Surgery
The goal of this randomized controlled clinical trial is to compare the pulmonary protective effects of two different positive end-expiratory pressure (PEEP) titrating methods in patients with non-injured lungs undergoing…
- Conditions
- Mechanical Power, Postoperative Pulmonary Complications (PPCs), Oxygenation
- Trial name
- TITRANT (NCT07170514)
- Testing
- EIT-guided PEEP titration, Cdyn-guided PEEP titration
- Where
- 3 sites in Hungary
- Volunteers
- 200 people
- Sponsor
- Pest County Flór Ferenc Hospital
Postoperative Pulmonary Complications (PPCs), Hypoxemia
Lung Ultrasound Score and Postoperative Pulmonary Complications in Major Non-Thoracic Surgery
This prospective observational cohort study aims to evaluate the predictive value of perioperative lung ultrasound (LUS) score in determining early postoperative oxygen requirement and pulmonary complications in patients…
- Trial name
- LUS-POSTOP (NCT07515001)
- Volunteers
- 97 people
- Sponsor
- Dicle University
Postoperative Pulmonary Complications (PPCs)
Intraoperative Nebulization of Lidocaine and Postoperative Pulmonary Complications
There is high incidence of postoperative pulmonary complications (PPCs) in patients undergoing major abdominal surgeries.PPCs significantly prolongs the hospital stay of patients, increases their economic burden, and raises the…
- Trial name
- NCT07000760
- Testing
- Nebulization of lidocaine, Nebulization of normal saline
- Where
- 2 sites in China
- Volunteers
- 270 people
- Sponsor
- Jun Zhang
Postoperative Pulmonary Complications (PPCs)
Perioperative Prophylactic Positive Pressure Ventilation Reduces Postoperative Pulmonary Complications.
The incidence of postoperative pulmonary complications (PPCs) ranges from 5% to 33%. PPCs significantly prolong hospital stay, increase the economic burden, and are associated with postoperative mortality at 30 days and 1 year.
- Trial name
- NCT07461285
- Testing
- Conventional Ventilation, Perioperative positive pressure ventilation
- Volunteers
- 206 people
- Sponsor
- Jun Zhang
Postoperative Pulmonary Complications (PPCs), Postoperative Atelectasis
Optimal PEEP Level for Minimizing the Risk of Postoperative Atelectasis: A Retrospective Cohort Study Based on Lung Ultrasound Monitoring
Background: After surgery with general anesthesia, it is common for parts of the lungs to collapse, a condition called atelectasis. This can lead to low blood oxygen levels and other lung complications.
- Conditions
- Postoperative Pulmonary Complications (PPCs), Postoperative Atelectasis, Lung Ultrasound
- Trial name
- ULTRASVENT-1 (NCT07211074)
- Where
- Russia
- Volunteers
- 450 people
- Sponsor
- State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia
Postoperative Atelectasis, Postoperative Pulmonary Atelectasis
Lung Ultrasound Assessment of Postoperative Atelectasis After Mechanical Ventilation With Minimum Driving Pressure
Brief summary The goal of this clinical trial is to compare two different types of perioperative mechanical ventilation (MV), specifically Protective Mechanical Ventilation (PMV) and MV with the lowest possible Driving Pressure…
- Conditions
- Postoperative Atelectasis, Postoperative Pulmonary Atelectasis, Postoperative Pulmonary Complications (PPCs), Lung Ultrasonography Score
- Trial name
- NCT07186920
- Testing
- PEEP titration for Minimum Driving Pressure, Lung Protective Ventilation
- Where
- Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University General Hospital of Patras