Postoperative Pulmonary Complications (PPCs)LUS-POSTOPNCT07515001
Lung Ultrasound Score and Postoperative Pulmonary Complications in Major Non-Thoracic Surgery
An observational study of Postoperative Pulmonary Complications (PPCs) and Hypoxemia, run by Dicle University.
Trial summary
This prospective observational cohort study aims to evaluate the predictive value of perioperative lung ultrasound (LUS) score in determining early postoperative oxygen requirement and pulmonary complications in patients undergoing major non-thoracic surgery. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Postoperative Pulmonary Complications (PPCs), Hypoxemia
- How many people
- 97 participants
- Where
- No sites listed yet
- Study dates
- Apr 2026to Jan 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Adult patients aged 18 to 65 years undergoing elective major non-thoracic surgery under general anesthesia with an expected surgical duration of 3 hours or longer at Dicle University Faculty of Medicine Hospital.
Who may be able to join
- Aged 18 to 65 years
- Scheduled for elective major non-thoracic surgery
- Undergoing surgery under general anesthesia
- Expected surgical duration of 3 hours or longer
- ASA physical status I-III
- Willing to participate in the study
- Provides written informed consent
Who cannot join
- Patients undergoing thoracic or cardiac surgery
- Advanced chronic lung disease (e.g., severe COPD or pulmonary fibrosis)
- History of previous lung resection
- Preoperative pneumonia or active pulmonary infection
- Body mass index greater than or equal to 40 kg/m2
- Pregnancy
Show all 9Show fewer
- Emergency surgery
- Planned postoperative mechanical ventilation or intensive care unit admission
- Refusal to participate in the study
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Predictive Value of Perioperative Lung Ultrasound Score for Early Postoperative Oxygen Requirement and Pulmonary Complications in Patients Undergoing Major Non-Thoracic Surgery
This prospective observational cohort study aims to evaluate the predictive value of perioperative lung ultrasound (LUS) score in determining early postoperative oxygen requirement and pulmonary complications in patients undergoing major non-thoracic surgery. Postoperative pulmonary complications remain a significant cause of morbidity and mortality in surgical patients. Lung ultrasound is a non-invasive, bedside imaging modality that allows real-time assessment of lung aeration and pathology. This study will investigate the association between perioperative LUS score and early postoperative respiratory outcomes, including oxygen requirement and pulmonary complications.
Read the detailed description
Postoperative pulmonary complications are among the most common causes of postoperative morbidity and prolonged hospital stay following major surgery. Early identification of patients at risk is crucial for timely intervention and improved outcomes. Lung ultrasound (LUS) has emerged as a reliable, non-invasive, and bedside tool for evaluating lung aeration and detecting pulmonary abnormalities such as atelectasis, interstitial syndrome, and pleural effusion.
This prospective observational cohort study is designed to assess the predictive value of perioperative lung ultrasound score in patients undergoing major non-thoracic surgery. A total of 97 patients aged between 18 and 65 years will be included. Lung ultrasound examinations will be performed perioperatively, and LUS scores will be calculated based on standardized protocols.
The primary objective of this study is to evaluate the relationship between perioperative LUS score and early postoperative oxygen requirement. Secondary objectives include assessing the association between LUS score and the incidence of postoperative pulmonary complications, need for intensive care unit admission, and length of hospital stay.
By identifying the predictive role of lung ultrasound scoring, this study aims to contribute to improved perioperative risk stratification and support the use of lung ultrasound as a practical tool in routine anesthetic and surgical care.
- Keywords
- lung ultrasound, Lus Score, Perioperative Ultrasound, Postoperative Complications, Oxygen Requirement, Non-Thoracic Surgery, Anesthesia
- Medical subject headings
- Hypoxia, Postoperative Complications
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| atients Undergoing Major Non-Thoracic Surgery | Patients aged 18 to 65 years undergoing major non-thoracic surgery who will be evaluated using perioperative lung ultrasound score to assess its association with early postoperative oxygen requirement and pulmonary complications. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Early Postoperative Oxygen Requirement
Assessment of the need for supplemental oxygen in the first 24 hours postoperatively and its association with perioperative lung ultrasound score.
Measured: Within the first 24 hours after surgery
Secondary outcomes (6)
Postoperative Pulmonary Complications
Incidence of postoperative pulmonary complications including atelectasis, pneumonia, pleural effusion, respiratory failure, pneumothorax, acute respiratory distress syndrome (ARDS), pulmonary edema, and need for reintubation.
Measured: Within 7 days after surgery
Correlation Between LUS Score and Hypoxemia
Evaluation of the relationship between perioperative lung ultrasound score and postoperative hypoxemia.
Measured: Within 24 hours after surgery
Number of participants requiring ICU admission
Requirement for postoperative intensive care unit admission.
Measured: Within 7 days after surgery
Length of Hospital Stay
Total duration of hospitalization measured in days.
Measured: From surgery until hospital discharge (up to 30 days)
Duration of Postoperative Oxygen Therapy
Total duration of supplemental oxygen therapy required during the first 24 hours postoperatively.
Measured: Within the first 24 hours after surgery
Number of participants requiring high-flow nasal oxygen or noninvasive ventilation
Requirement for advanced respiratory support including high-flow nasal oxygen or noninvasive ventilation in the postoperative period.
Measured: Within 7 days after surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Apr 2026
- Study startApr 2026 (estimated)
- Primary completionDec 2026 (estimated)
- Study completionJan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Postoperative Pulmonary Complications (PPCs)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 97 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Dicle University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Huseyi̇n Ceti̇k, Dicle University
- Investigators
- Zeynep Baysal Yildirim, MD,Professor, Principal investigator, Dicle University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07515001
- Sponsor's protocol ID
- DICLE-ANES-001
- Acronym
- LUS-POSTOP
- Status last verified
- Mar 2026
- First submitted
- 25 Mar 2026
- Last updated
- 7 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared due to institutional policies and ethical considerations regarding patient confidentiality.
Study at a glance
From the registry record, last updated by the sponsor on 7 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Predictive Value of Perioperative Lung Ultrasound Score for Early Postoperative Oxygen Requirement and Pulmonary Complications in Patients Undergoing Major Non-Thoracic Surgery
- ClinicalTrials.gov ID
- NCT07515001
- Acronym / sponsor ID
- LUS-POSTOP / DICLE-ANES-001
- Keywords
- lung ultrasound, Lus Score, Perioperative Ultrasound, Postoperative Complications, Oxygen Requirement, Non-Thoracic Surgery, Anesthesia
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 97 participants (estimated)
- Lead sponsor
- Dicle UniversityUniversity, hospital or other
- Study start
- Apr 2026 (estimated)
- Primary completion
- Dec 2026 (estimated)
- Study completion
- Jan 2027 (estimated)
- First posted
- 7 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This prospective observational cohort study aims to evaluate the predictive value of perioperative lung ultrasound (LUS) score in determining early postoperative oxygen requirement and pulmonary complications in patients undergoing major non-thoracic surgery. Postoperative pulmonary complications remain a significant cause of morbidity and mortality in surgical patients. Lung ultrasound is a non-invasive, bedside imaging modality that allows real-time assessment of lung aeration and pathology. This study will investigate the association between perioperative LUS score and early postoperative respiratory outcomes, including oxygen requirement and pulmonary complications.
Detailed description
Postoperative pulmonary complications are among the most common causes of postoperative morbidity and prolonged hospital stay following major surgery. Early identification of patients at risk is crucial for timely intervention and improved outcomes. Lung ultrasound (LUS) has emerged as a reliable, non-invasive, and bedside tool for evaluating lung aeration and detecting pulmonary abnormalities such as atelectasis, interstitial syndrome, and pleural effusion.
This prospective observational cohort study is designed to assess the predictive value of perioperative lung ultrasound score in patients undergoing major non-thoracic surgery. A total of 97 patients aged between 18 and 65 years will be included. Lung ultrasound examinations will be performed perioperatively, and LUS scores will be calculated based on standardized protocols.
The primary objective of this study is to evaluate the relationship between perioperative LUS score and early postoperative oxygen requirement. Secondary objectives include assessing the association between LUS score and the incidence of postoperative pulmonary complications, need for intensive care unit admission, and length of hospital stay.
By identifying the predictive role of lung ultrasound scoring, this study aims to contribute to improved perioperative risk stratification and support the use of lung ultrasound as a practical tool in routine anesthetic and surgical care.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| atients Undergoing Major Non-Thoracic Surgery | – | –Patients aged 18 to 65 years undergoing major non-thoracic surgery who will be evaluated using perioperative lung ultrasound score to assess its association with early postoperative oxygen requirement and pulmonary complications. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Adult patients aged 18 to 65 years undergoing elective major non-thoracic surgery under general anesthesia with an expected surgical duration of 3 hours or longer at Dicle University Faculty of Medicine Hospital.
Key inclusion criteria (7 listed)
- Aged 18 to 65 years
- Scheduled for elective major non-thoracic surgery
- Undergoing surgery under general anesthesia
- Expected surgical duration of 3 hours or longer
- ASA physical status I-III
Key exclusion criteria (9 listed)
- Patients undergoing thoracic or cardiac surgery
- Advanced chronic lung disease (e.g., severe COPD or pulmonary fibrosis)
- History of previous lung resection
- Preoperative pneumonia or active pulmonary infection
- Body mass index greater than or equal to 40 kg/m2
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Early Postoperative Oxygen Requirement
Time frame: Within the first 24 hours after surgery
Assessment of the need for supplemental oxygen in the first 24 hours postoperatively and its association with perioperative lung ultrasound score.
6 secondary outcomes
Postoperative Pulmonary Complications
Time frame: Within 7 days after surgery
Correlation Between LUS Score and Hypoxemia
Time frame: Within 24 hours after surgery
Number of participants requiring ICU admission
Time frame: Within 7 days after surgery
Length of Hospital Stay
Time frame: From surgery until hospital discharge (up to 30 days)
Duration of Postoperative Oxygen Therapy
Time frame: Within the first 24 hours after surgery
Number of participants requiring high-flow nasal oxygen or noninvasive ventilation
Time frame: Within 7 days after surgery
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Apr 2026.
- Individual participant dataSharing planned: No. Individual participant data will not be shared due to institutional policies and ethical considerations regarding patient confidentiality.
Related trials for Postoperative Pulmonary Complications (PPCs)
Recruiting
PROtective Ventilation With FLOW-Controlled Ventilation
Postoperative Pulmonary Complications (PPCs), Feasibility Studies
Not yet recruiting
Flow-Controlled Ventilation to Improve Postoperative Pulmonary Outcome After Thoracic Surgery
Mechanical Ventilation, Postoperative Pulmonary Complications (PPCs)
Not yet recruitingObservational study
Physical Function Before Surgery and Lung Complications After Lung Surgery
Postoperative Pulmonary Complications (PPCs), Preoperative Functional Status
Enrolling by invitation
Evaluation of the Effectiveness of Lung-Protective Ventilation in Patients Undergoing Laparoscopic Gastrectomy
Postoperative Pulmonary Complications (PPCs), Atelectasis
Recruiting
Early Postoperative Physiotherapy to Prevent Respiratory Insufficiency After Elective Heart Surgery
CABG, Respiratory Insufficiency
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Zeynep Baysal Yildirim, MD,Professor principal investigator
Dicle University
Questions about this trial
What is this clinical trial studying?
An observational study of Postoperative Pulmonary Complications (PPCs) and Hypoxemia, run by Dicle University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 7 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Huseyin Cetik, MD (+90 538 970 0171, huseyincetik@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Early Postoperative Oxygen Requirement (time frame: Within the first 24 hours after surgery). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Apr 2026.