Clinical trials: Posterior Circulation
Acute Ischemic Stroke
Pro-urokinase for Extended-Window Posterior Circulation Stroke
This study aims to evaluate whether, in patients with imaging-confirmed acute ischemic stroke of the posterior circulation presenting within 4.5-24 hours after symptom onset and not scheduled for endovascular thrombectomy…
- Trial name
- PROMISE (NCT07617870)
- Testing
- rhPro-UK, Aspirin
- Where
- China
- Volunteers
- 586 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Bilateral Iliac Artery Ligation, Postpartum Hemorrhage
Influence of BIIAL Following PPH on Dorsal Clitoral Artery Blood Flow and FSFI
Dorsal clitoral artery Doppler examinations in women with bilateral internal iliac artery ligation due to postpartum hemorrhage (study group) and age-matched healthy puerperal women were performed regularly in the postoperative…
- Trial name
- NCT02409602
- Testing
- Doppler ultrasonographic examination
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
Mechanical Thrombectomy, General Anesthesia
Multicentre ObseRvational Study in Posterior mecHanical thrombEctomy: conscioUs Sedation vs General aneSthesia
The association of conscious sedation vs. general anesthesia in ischemic stroke with posterior circulation occlusions undergoing endovascular therapy, is istill unknown.
- Conditions
- Mechanical Thrombectomy, General Anesthesia, Conscious Sedation, Posterior Circulation
- Trial name
- NCT05082896
- Testing
- Type of anesthesia choice
- Where
- Spain
- Volunteers
- 453 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Non-specific Low Back Pain
The Effects of Blood Flow Restriction-based Abdominal draw-in Maneuver on Activation of Abdominal Core Muscles in Patients With Non-specific Low Back Pain
The transverse abdominis (TrA) is the deepest muscle layer of lateral and anterior abdominal wall and also known as a significant component of core stability.
- Trial name
- NCT05996341
- Testing
- blood flow restriction
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Chronic Rhinitis
Effects of Radiofrequency Ablation of Posterior Nasal Nerves on Inflammatory Cytokines, Peak Nasal Inspiratory Flow, and Nasal Blood Flow in Patients With Chronic Rhinitis
The purpose of this study is to assess the effectiveness of radiofrequency ablation (RFA) of the posterior nasal nerve (PNN) in chronic rhinitis (CR) patients by comparing patient reflective total nasal symptom score (rTNSS) and…
- Trial name
- NCT05648565
- Testing
- Radiofrequency ablation (RFA)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- The University of Texas Health Science Center, Houston
Low Back Pain
Low Blood Flow Restriction Training on Low Back Pain
The aim of this randomized controlled trial is to find the effectiveness of low load blood restriction training on improving hamstring muscle strength, alleviating pain and reducing functional disability in nonspecific low back…
- Trial name
- NCT07576101
- Testing
- Conventional PT, Low Blood Flow Restriction Training
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Low Back Pain
Impact of Combined CST, BFR, and Tai Chi on Muscle Physiology and Functional Characteristics Among Adults With LBP
Background: Low back pain (LBP) is highly prevalent globally, affecting people of all ages(Wu et al., 2020). In China, LBP is a leading cause of disease burden(Wu et al., 2019).
- Trial name
- NCT06599645
- Testing
- CST+BFR+Tai Chi+Education, CST+BFR+Education, Tai Chi +BFR+Education
- Volunteers
- 52 people
- Sponsor
- Universiti Teknologi Mara
Posterior Circulation Brain Infarction
Choice of Anesthesia for Endovascular Treatment of Acute Ischemic Stroke in Posterior Circulation
There is few randomized controlled clinical to investigated the impact of anesthetic type on outcome in patients with acute ischemic stroke in posterior cerebral circulation.
- Trial name
- CANVAS-II (NCT03317535)
- Testing
- General anesthesia, Local anesthesia/concious sedation, Spontaneous breath
- Where
- 2 sites in China
- Volunteers
- 93 people
- Sponsor
- Beijing Tiantan Hospital
Low Back Pain
Changes in Blood Flow in the Application of Magnetic Tape in Patients With Low Back Pain. RCT
A tape is applied over the lumbar 4th and lumbar 5th levels crosswise in people with low back pain. The possible variation of the arterial flow of the femoral artery is measured with ultrasound.
- Trial name
- NCT04836468
- Testing
- Tape application
- Where
- Spain
- Volunteers
- 22 people
- Sponsor
- Francisco Selva
Endovascular Thrombectomy
Medical Imaging Screening for Posterior-circulation Ischemic Stroke
Patients with ischemic stroke in the posterior circulation continue to have high rates of mortality and disability, even with aggressive treatment.
- Trial name
- NCT06094569
- Testing
- Endovascular Therapy
- Where
- 4 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Tianjin Huanhu Hospital
Low Back Pain, Knee Osteoarthritis
Ischemic Preconditioning in Osteoarthritis and Back Pain
We are examining the use of restricted blood flow, through full occlusion, on a single thigh for 50 minutes (5 minutes on, 5 minutes off), completed every other day for 2 weeks to improve function in individuals with knee…
- Trial name
- NCT07003113
- Testing
- Ischemic Preconditioning
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Illinois at Chicago
Stroke, Acute Ischemic
EXtending the Time Window for Thrombolysis in Posterior Circulation Stroke Without Early CT Signs
The primary hypothesis being tested in this trial is that ischemic stroke patients in posterior circulation at 4.5 - 24 hours post onset of stroke will have improved clinical outcomes when given intravenous tissue plasminogen…
- Trial name
- NCT05429476
- Testing
- Tissue Plasminogen Activator (Alteplase)
- Where
- 27 sites in China
- Volunteers
- 234 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cardiac Surgery, Hypertension, Pulmonary
The Effect of Pituitrin on the Patients With Pulmonary Hypertension Undergoing Cardiac Surgery
This study is a parallel group, single blind, randomized controlled trial. Patients with pulmonary hypertension who met the inclusion criteria and planned to undergo elective cardiac surgery under cardiopulmonary bypass from July…
- Trial name
- NCT05727618
- Testing
- Pituitrin, normal saline
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Qianfoshan Hospital
Diabetic Macular Edema
Anterior and Posterior Segment Vascular Changes Following Laser and Anti-Vascular Endothelial Growth Factor (VEGF) Treatment of Diabetic Retinopathy
The study will investigate changes in the structure and function of blood vessels in the front and back of the eye following laser and anti-VEGF treatments for sight-threatening diabetic eye disease.
- Trial name
- VEGF (NCT01196325)
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Ischemic Stroke
Acetyl-leucine in Post-stroke Ataxia
Along with the current clinical trial, the efficacy and safety of 4 gram of acetyl-leucine daily for three months in patients with post-stroke ataxia following posterior-circulation ischaemic stroke assessed through BBS, SARA…
- Trial name
- NCT07275749
- Testing
- Acetyl-Leucine, Clopidogrel 75 Mg Oral Tablet, aspirin 100mg
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Kafrelsheikh University
Congenital Heart Disease
Cerebral Oximetric Monitoring of the Posterior Circulation
One known risk of pediatric heart surgery is the possibility for brain damage. This problem results from a lack of oxygen rich blood flow to the brain during surgery.
- Trial name
- CerebralOx (NCT00751712)
- Testing
- Cerebral oximeter sensor
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Upper Crossed Syndrome
The Effects of Dynamic Taping Combined With Corrective Exercises on Cervical Proprioception and Muscle Imbalance in Patients With Upper Crossed Syndrome
Upper Crossed Syndrome (UCS) is a pattern of muscle imbalance that leads to forward head posture, rounded shoulders, or excessive thoracic kyphosis, thereby affecting posture and cervical-shoulder function.
- Trial name
- NCT07182461
- Testing
- Dynamic Tape, Swiss Ball, Dumbbells
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Acute Ischemic Stroke, Endovascular Thrombectomy
Minocycline After Successful Endovascular Thrombectomy Recanalization in Posterior Circulation Arterial Occlusion (ATTRACTION-MINOP)
Acute ischemic stroke (AIS) is a leading cause of mortality and long-term disability worldwide. Among these, stroke caused by large vessel occlusion (LVO) are associated with particularly poor outcomes.
- Conditions
- Acute Ischemic Stroke, Endovascular Thrombectomy, Minocycline, Posterior Circulation
- Trial name
- NCT07594301
- Testing
- Minocycline hydrochloride capsule
- Where
- China
- Volunteers
- 234 people
- Sponsor
- Xiang Luo
Vertigo
A Study To Evaluate The Efficacy And Safety Of Betahistine Mesilate In The Treatment Of Patients With Vertigo Caused By Cerebral Infarction In Posterior Circulation
The purpose of this study is to determine the efficacy and safety of Betahistine Mesilate in the treatment of patients with vertigo caused by Cerebral Infarction in posterior circulation.
- Trial name
- NCT00474409
- Testing
- Merislon
- Where
- 4 sites in China
- Sponsor
- Eisai Inc.
Ischemic Stroke
Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Posterior Circulation Large Vessel Occlusion Stroke
This is an investigator-initiated phase III clinical trial employing a randomized, double-blind, placebo-controlled design. The primary objective of this study is to investigate the efficacy and safety of an interleukin-6…
- Trial name
- IRIS-3 (NCT07509645)
- Testing
- Tocilizumab
- Where
- 30 sites in China
- Volunteers
- 348 people
- Sponsor
- Capital Medical University