Clinical trials: Posterior Circulation
Sub-acute Non-specific Low Back Pain
Low Load Blood Flow Restriction Training Versus Traditional Heavy Load Resistance Training in Male Athletes With Sub-acute Non-specific Low Back Pain
his randomized clinical trial aims to compare the effects of low-load blood flow restriction (LL-BFR) training and traditional heavy-load resistance training (HL-RT) on male athletes with sub-acute non-specific low back pain.
- Trial name
- NCT07480759
- Testing
- Low Load Blood Flow Restriction Training (LL-BFR), Traditional Heavy Load Resistance Training (HL-RT)
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- University of Lahore
Acute Stroke, Ischemic Stroke, Acute
Rescue Extracranial Vertebral Stenting in Tandem Occlusions
The acute vertebrobasilar occlusion associated with the poor prognosis, particularly tandem occlusion. However, few data on the efficacy of the endovascular therapy was indicated in this occlusion.
- Conditions
- Acute Stroke, Ischemic Stroke, Acute, Vertebro Basilar Ischemia
- Trial name
- REVET (NCT06365294)
- Testing
- Rescue extracranial stenting
- Where
- Vietnam
- Volunteers
- 9 people
- Sponsor
- Dr. Cuong Tran Chi
Adolescent Athletic Performance, Muscle Strength Development
Effects of Back Squat Exercise with or Without Blood Flow Restriction in Healthy Adolescent Basketball Athletes
The goal of this clinical trial is to assess the effectiveness of Blood Flow Restriction (BFR) training compared to traditional high-intensity training in adolescent basketball players aged 16-18.
- Conditions
- Adolescent Athletic Performance, Muscle Strength Development, Jump Height Improvement, Ground Reaction Force (GRF) Enhancement
- Trial name
- BFR (NCT06684093)
- Testing
- Back squat with Blood flow restriction machine, Back squats
- Where
- Lebanon
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- St Joseph University, Beirut, Lebanon
Acute Ischemic Stroke, Intracranial Artery Occlusion
Intra-arterial TNK Following Endovascular Thrombectomy in Patients With Large Vessel Occlusion of Posterior Circulation
Rationale: Recently, one prospective multicenter RCT reported a potential beneficial effect of intra-arterial alteplase following successful endovascular thrombectomy (EVT) in patients with an acute intracranial large vessel…
- Conditions
- Acute Ischemic Stroke, Intracranial Artery Occlusion, Endovascular Thrombectomy
- Trial name
- NCT05684172
- Testing
- Tenecteplase, endovascular thrombectomy alone
- Where
- China
- Volunteers
- 208 people
- Sponsor
- The First Affiliated Hospital of University of Science and Technology of China
Ischemic Stroke
Total Posterior-circulation Infarct Volume in Basilar Artery Stroke
Preprocedural predictors of outcome in patients with acute basilar artery occlusion (ABAO) who underwent endovascular treatment (EVT) remain controversial.
- Trial name
- TPCIV-ABAO (NCT04650022)
- Testing
- Mechanical thrombectomy
- Where
- France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Montpellier
Infarction, Middle Cerebral Artery, Infarction, Anterior Cerebral Artery
Effect of Mesenchymal Stem Cells(MSCs) Transplantation for Acute Cerebral Infarction Patients
This is a placebo controlled, randomized, double blinded study including Phase 1 and Phase 2. Phase I study is a safety assessment and Phase 2 study is incline to assess effectiveness of MSCs.
- Conditions
- Infarction, Middle Cerebral Artery, Infarction, Anterior Cerebral Artery, Cerebral Infarction, Stroke, Ischemic
- Trial name
- NCT04093336
- Testing
- human umbilical cord mesenchymal stem cells, standardized treatment
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai East Hospital
Cerebral Aneurysm, Aneurysm, Middle Cerebral Artery
Safety Study of Minimally Invasive Approaches to Unruptured Anterior Circulation Aneurysms
The study is designed to evaluate the efficacy and safety of minimally invasive neurosurgical techniques for patients with incidental cerebral aneurysms of the anterior circulation in the Hospital das Clínicas of the University…
- Conditions
- Cerebral Aneurysm, Aneurysm, Middle Cerebral Artery, Aneurysm, Anterior Communicating Artery, Aneurysm, Posterior Communicating Artery
- Trial name
- MININCRUSP (NCT02345395)
- Testing
- Aneurysm Clipping
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Sao Paulo General Hospital
Basilar Artery Occlusion, Posterior Circulation Brain Infarction
Cerebrolysin as an Add-On Therapy to Standard Treatment of Basilar Artery Occlusion
The standard therapy for acute ischemic posterior circulation stroke (PCS) often leads to poor functional outcomes and high mortality rates, despite all advances in reperfusion therapy.
- Trial name
- NCT06489925
- Testing
- Cerebrolysin
- Volunteers
- 20 people
- Sponsor
- University Hospital Sestre Milosrdnice
Posterior Circulation Acute Ischemic Stroke Due to Large Vessel Occlusion of the Vertebral or Basilar Artery Needing Endovascular Thrombectomy
PRECISE (PERFUSION IMAGING TO IDENTIFY POSTERIOR CIRCULATION CANDIDATES FOR THROMBECTOMY)
We hypothesize that patients with a favorable Critical Area Perfusion Score (CAPS≤3) on cerebral perfusion imaging will have a favorable response to revascularization by thrombectomy and that patients with a CAPS>3 will not
- Trial name
- SWISS-PRECISE (NCT06375174)
- Testing
- Thrombectomy
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Dr. med. Carlo Cereda
Acute Ischemic Stroke, Basilar Artery Occlusion
Endovascular Therapy for Acute Basilar Artery Occlusion With Large Ischemic Core
Acute basilar artery occlusion is associated with high mortality and severe disability. Previous randomized trials have demonstrated the benefit of endovascular therapy in selected patients with basilar artery occlusion; however…
- Conditions
- Acute Ischemic Stroke, Basilar Artery Occlusion, Large Ischemic Core
- Trial name
- NCT07672795
- Testing
- Endovascular Therapy, Best Medical Management
- Where
- China
- Volunteers
- 256 people
- Sponsor
- The First Affiliated Hospital of University of Science and Technology of China
Basilar Artery Occlusion
Extending the Time Window for Tenecteplase by Recanalization of Basilar Artery Occlusion in Posterior Circulation Stroke
Patients presenting to the emergency department with an acute ischemic stroke due to basilar artery occlusion within 24 hours of stroke onset will be assessed to determine their eligibility for randomization into the trial.
- Trial name
- POST-ETERNAL (NCT05105633)
- Testing
- Tenecteplase, Standard Care (which may include intravenous Alteplase)
- Where
- 17 sites in Australia, Brazil and 1 more
- Volunteers
- 688 people
- Sponsor
- University of Melbourne
Posterior Ischemic Stroke, Cerebral Infarction
Derivation and External Validation of the "FORECAST-PC" Prediction Scores
This study aims to develop and externally validate machine learning prediction models (FORECAST-PC) to determine 90-day functional outcomes for patients suffering from acute ischemic stroke in the posterior circulation who are…
- Conditions
- Posterior Ischemic Stroke, Cerebral Infarction, Cerebrovascular Disorders
- Trial name
- FORECAST-PC (NCT07750015)
- Testing
- FORECAST-PC Prediction Models
- Where
- Switzerland
- Volunteers
- 732 people
- Sponsor
- Dr. med. Alexander Salerno, MD-PhD
Acute Ischemic Stroke, Arterial Thrombosis
Intra-arterial Thrombolysis After Successful Thrombectomy for Acute Ischemic Stroke in the Posterior Circulation (IAT-TOP)
The CHOICE study suggested that the use of adjunct intra-arterial alteplase after successful endovascular reperfusion in large vessel occlusion acute ischemic strokes may result in a greater likelihood of excellent neurological…
- Conditions
- Acute Ischemic Stroke, Arterial Thrombosis, Posterior Circulation Brain Infarction
- Trial name
- NCT05897554
- Testing
- intra-arterial alteplase
- Where
- China
- Volunteers
- 247 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke of Basilar Artery, Optical Coherence Tomography
Optical Coherence Tomography Guided Antithrombotic Treatment After Endovascular Thrombectomy of the Posterior Circulation
Evidence regarding the role of early (<24 hours) antithrombotics post-revascularization with either intravenous thrombolysis (IVT), endovascular thrombectomy (EVT), or a combination of both remains scarce.
- Conditions
- Stroke of Basilar Artery, Optical Coherence Tomography, Antithrombotics, Endovascular Thrombectomy
- Trial name
- NCT04121611
- Testing
- Unfractionated heparin, Acetylsalicylic Acid (ASA)
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Sunnybrook Health Sciences Centre
Brain Tumor
Cerebral Blood Circulation in Patients With Posterior Fossa Brain Tumor
The normal cerebral blood flow is guided by factors such as cerebral autoregulation (CA) and carbon dioxide reactivity (CO2R). Authors have demonstrated that CA and CO2R may be impaired in presence of intracranial tumors.Most…
- Trial name
- NCT01476670
- Testing
- Monitoring
- Where
- India
- Volunteers
- 20 people
- Sponsor
- All India Institute of Medical Sciences
Placenta Previa
Relation of Implantation Site to Placental Site in Presence or Absence of Cesarean Section Scar
After gaining verbal consent , Patients included in this study will be subjected to: 1. history taking : peronal history . obstetric history. past history 2. general examination including vital signs 3.
- Trial name
- NCT03208842
- Testing
- trans vaginal ultrasound
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Posterior Circulation Ischemic Stroke
Endovascular Treatment for Posterior Circulation Ischemic Stroke Post 1 Day （24 Hours）
To evaluate the efficacy and safety of endovascular therapy for posterior circulation ischemic stroke presenting more than 24 hours after symptom onset.
- Trial name
- ETP1-PC (NCT07699029)
- Testing
- Endovascular treatment combined with standard pharmacological treatment, Standard pharmacological treatment
- Where
- China
- Volunteers
- 244 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Basilar Artery Occlusion
Contact Aspiration Versus Stent Retriever for Recanalisation of Acute Stroke Patients With Basilar Artery Occlusion: The Posterior Circulation ASTER Randomized Trial Protocol
Acute ischemic stroke (AIS) patients with basilar artery occlusion (BAO) present a devastating, life-threatening prognosis. Urgent recanalization with endovascular mechanical thrombectomy is routinely performed in patients with…
- Trial name
- pc-ASTER (NCT05320263)
- Testing
- Contact aspiration Thrombectomy, Stent retriever thrombectomy
- Where
- 12 sites in France
- Volunteers
- 480 people
- Sponsor
- Hopital Foch
Healthy Volunteers, Low Back Pain
Effects of Blood Flow Restriction Exercises on Lumbar Muscle Endurance and Balance in Healthy Young Adults
This study aims to examine the effects of blood flow restriction (BFR) exercises on back muscle endurance and balance in healthy young adults.
- Conditions
- Healthy Volunteers, Low Back Pain, Postural Balance, Muscle Fatigue
- Trial name
- BFR-LUMBEX (NCT07182812)
- Testing
- Blood Flow Restriction Sit-to-Stand Exercise, Sit-to-Stand Exercise without Blood Flow Restriction
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Guler
Ischemic Stroke
Remote Ischemic Conditioning for Acute Moderate Posterior Ischemic Stroke
A substantial body of basic and clinical research has demonstrated the protective effects of remote ischemic conditioning (RIC) in ischemic stroke.
- Trial name
- RICAMIS2 (NCT06931535)
- Testing
- remote ischemic conditioning
- Where
- China
- Volunteers
- 1,600 people
- Sponsor
- General Hospital of Shenyang Military Region