Clinical trials: Post Stroke Recovery
Stroke, Upper Extremity Hemiplegia
"Remind-to-move" for Promoting Upper Extremity Recovery in Patients With Stroke After Subacute Discharge
This is a multi-centered randomized controlled trial to investigate the effects of "Remind-to-Move" (RTM) using wearable devices at home for promoting upper extremity recovery in stroke patients after discharge from subacute…
- Trial name
- NCT02952677
- Testing
- Remind-to-move, Control
- Volunteers
- 84 people
- Sponsor
- The Hong Kong Polytechnic University
Chronic Stroke, Subacute Stroke
IMPULSE - StIMulation of Brain Plasticity to Improve Upper Limb Recovery After StrokE
Stroke is a leading cause of adult long-term disability worldwide. Recovery of arm and hand function after stroke is limited to about 50% of patients and full recovery is achieved in only 12% of stroke survivors by 6 months after…
- Trial name
- IMPULSE (NCT04124367)
- Testing
- Cerebrolysin, non-invasive brain stimulation
- Where
- Austria
- Volunteers
- 4 people
- Sponsor
- Ever Neuro Pharma GmbH
Cerebral Vascular Accident (CVA)/Stroke
The Natural History of Recovery After Stroke
The goal of this longitudinal observational study is to learn the course of recovery after stroke. Specifically, in this study we will learn and describe the changes in cognitive, motor and sensory function over time in stroke…
- Trial name
- RESTRO (NCT06441552)
- Testing
- non-interventional
- Where
- 3 sites in Israel, Palestinian Territories
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Adi Negev-Nahalat Eran
Stroke
Effect of tDCS on Brain Organization and Motor Recovery
Neurological deficits and motor disorders are extremely common after stroke. Physical therapies can improve the autonomy of these patients, but despite an intensive stationary neurorehabilitation, severe deficits often persist.
- Trial name
- ESTCORM (NCT03342534)
- Testing
- DC-stimulator (Neuroconn, Germany)
- Where
- 2 sites in Switzerland
- Volunteers
- 36 people
- Sponsor
- Adrian Guggisberg
Stroke, Acute
Early Neurological Clinical Recovery, 3 Months After Endovascular Treatment of an Acute Ischemic Stroke
This trial aims at collecting standardized data concerning the early neurological clinical recovery of patients, 3 months after endovascular treatment of an acute ischemic stroke.
- Trial name
- AVC-endovasc (NCT02879123)
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Stroke, Hemiparesis
Personalized Robotic Telerehabilitation for Upper Limb Functional Recovery After Stroke in a Home-Based Setting
Stroke is a leading cause of long-term disability worldwide, with upper-limb impairment representing a major determinant of functional limitation and reduced independence.
- Conditions
- Stroke, Hemiparesis, Upper Extremity Paresis, Motor Impairment
- Trial name
- ROBOHOME (NCT07590349)
- Testing
- Robotic-Assisted Telerehabilitation Virtual Reality-Based Telerehabilitation, Virtual reality-based rehabilitation platform without robotic assistance
- Volunteers
- 70 people
- Sponsor
- University of Campania Luigi Vanvitelli
Chronic Cerebral Ischemia
Safety and Efficacy of Sequential Therapy With Mexidol® in Patients With Chronic Cerebral Ischemia
The purpose of this study is to evaluate safety and efficacy of sequential treatment with Mexidol® in patients with chronic cerebral ischemia (CCI).
- Trial name
- MEMO (NCT06834490)
- Testing
- Mexidol
- Where
- 14 sites in Russia, Uzbekistan
- Volunteers
- 318 people
- Sponsor
- Pharmasoft
Stroke, Compliance, Patient
Telemedicine Efficacy in Medication Adherence in Post-ischemic Stroke Patients
Telemedicine is an incipient resource to support the stroke system of care in Colombia. Several studies had demonstrated that patients benefit by implementing telestroke, for instance, providing timely and appropriate…
- Conditions
- Stroke, Compliance, Patient, Compliance, Treatment, Compliance, Medication
- Trial name
- NCT04877171
- Testing
- telemedicine neurology consultation, in-person neurology consultation
- Where
- Colombia
- Volunteers
- 84 people
- Sponsor
- Fundación Cardiovascular de Colombia
Intracerebral Hemorrhage
ROSE-Longitudinal Assessment With Neuroimaging
The investigators will perform follow-up on 250 of 500 cases recruited into the ROSE study of cases with deep and lobar intracerebral hemorrhage to perform advanced neuroimaging at 12-24 months post stroke, and evaluations of…
- Trial name
- ROSE-LAWN (NCT05089331)
- Where
- 7 sites in United States
- Volunteers
- 250 people
- Sponsor
- State University of New York at Buffalo
Stroke
ExoDoF: Robotic Exoskeleton for Upper Limb Motor Rehabilitation After Stroke
Two decades ago, the projection of recovery of the upper extremity (UE) after a stroke had a very poor prognosis worldwide. Nowadays, thanks to medical advances and early rehabilitation, the prognosis for recovery has improved…
- Trial name
- NCT06496529
- Testing
- DoF intervention, Task intervention
- Where
- 4 sites in Chile
- Volunteers
- 44 people
- Sponsor
- University of Chile
Aphasia, Chronic Stroke
Transcutaneous Vagus Nerve Stimulation in Aphasia After Stroke
Aphasia is an acquired language disorder. Stroke is the most common cause of aphasia, which affects 30% of stroke survivors. Speech and Language Therapy (SLT) can help people with aphasia but it may not be provided at the…
- Trial name
- TRANSLATE (NCT06403475)
- Testing
- Transcutaneous Vagus Nerve Stimulation, Computer Based Speech and Language Therapy (Step by Step)
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Aphasia, Stroke
fMRI of Language Recovery Following Stroke in Adults
The purpose of this study is to test the effectiveness of constraint-induced aphasia therapy.
- Trial name
- NCT00843427
- Testing
- CIAT
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Alabama at Birmingham
Stroke
Evaluation of the Effect of Dextro-Amphetamin Added to Physiotherapy in Patients After Stroke
The aim of the study is to evaluate the effect of Dextro-amphetamin added to physiotherapy on motor recovery in patients after stroke. The study is a double-blinded placebo-controlled randomised controlled trial.
- Trial name
- NCT00572767
- Testing
- Dextro-Amphetamin, Glucose
- Where
- Switzerland
- Volunteers
- 16 people
- Sponsor
- Reha Rheinfelden
Stroke
Prospective Cohort Study : Evaluation of Prognosis Criteria for Walking Independently Recovery After Stroke.
Based on a 2017 US study that developed an algorithm for predicting independent walking recovery after stroke, we propose a prospective study to assess the validity and applicability of this algorithm in the majority of stroke…
- Trial name
- NCT05572892
- Testing
- FAC scale
- Where
- France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Caen
Atomoxetine Hydrochloride, Placebos
Post-stroke Neural Plasticity With Atomoxetine
This proposal evaluates the safety and effectiveness of a noradrenergic drug named atomoxetine combined with motor training to enhance cortical plasticity and improve hand function after stroke.
- Trial name
- NCT02788357
- Testing
- Atomoxetine
- Volunteers
- 12 people
- Sponsor
- Lumy Sawaki
Stroke
Aha BOOST Arm-hand BOOST Therapy to Enhance Recovery After Stroke: Clinical, Health Economic and Process Evaluation
The overall aim of this study is to establish the clinical- and cost-effectiveness of the arm-hand BOOST therapy when delivered on top of the usual care program in the sub-acute phase post stroke and to perform a process…
- Trial name
- AHA-BOOST (NCT06517251)
- Testing
- Arm-hand BOOST, Lower limb BOOST
- Where
- 2 sites in Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Stroke
GoHand(TM) to Enhance Recovery of Arm and Hand Function Post-Stroke
This is a proof-of-concept study aimed at contributing evidence towards the need, usability and efficacy potential of the GoHandTM sensor in people with reduced hand function post-stroke.
- Trial name
- GoHand (NCT05321446)
- Testing
- GoHand(TM)
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- McGill University
Stroke
Locomotor Recovery and Compensation Post-stroke (LRC)
The proposed research will characterize of the time course of neurological and locomotor recovery as well as development of compensatory strategies throughout sub-acute and chronic phases post stroke.
- Trial name
- LRC (NCT05081713)
- Testing
- high-intensity training focused on stepping in variable contexts
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Indiana University
Stroke
Comparing Different Rehabilitation Exercise Strategies for Improving Arm Recovery After Stroke
The purpose of this research study is to measure the effect of participating in extra arm exercise in addition to standard rehabilitation exercises in the Acute Rehabilitation Unit.
- Trial name
- Boost (NCT05880940)
- Testing
- Boost - Moveable Wheelchair Armrest, Electronic Arm and Hand Exercise Program
- Where
- 3 sites in United States
- Volunteers
- 35 people
- Sponsor
- University of California, Irvine
Stroke
Comparison of Fatigue and Recovery After Stroke Depending on the Usual Management With or Without Physical Training
After a minor stroke, patients frequently report complaints such as fatigue and difficulty with certain everyday motor tasks, leading to a marked deterioration in their quality of life.
- Trial name
- FRAM (NCT03259932)
- Testing
- no physical activity, physical activity
- Sponsor
- Centre Hospitalier Universitaire Dijon