Clinical trials: Post Induction Hypotension
Anesthesia, Hemodynamic Instability
Anesthesia Induction with the Target-controlled Infusion of Propofol in High-risk Patients
The purpose of this study is to compare the risk of hypotension following induction of anesthesia in high-risk patients (American Society of Anesthesiologists risk scores III and IV) using target-controlled infusion (TCI) of…
- Trial name
- NCT06535230
- Testing
- Manual anesthesia induction, Anesthesia induction with Target controlled infusions (TCI), Hemodynamic monitoring with pressure recording analytical method (PRAM)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Acibadem University
Anesthesia, General, Hypotension
Can Continuous Cardiac Output Monitoring Before General Anesthesia Predict Hypotension After Induction?
Post-induction hypotension (PIH) is very common with high incidence about 9-60%. There are multiple factors that may cause PIH, like pre-operative fasting, bowel preparation, vasodilatation due to anesthetics, and reduced…
- Conditions
- Anesthesia, General, Hypotension, Cardiac Output
- Trial name
- NCT03718949
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Post-induction Hypotension
Management of Post-Induction Hypotension in Emergency Abdominal Surgery
The goal of this clinical trial is to compare the efficacy of two vasopressors (norepinephrine vs. ephedrine) in treating hypotension in adult patients (aged 18+, ASA I-III) undergoing general anesthesia for abdominal surgical…
- Trial name
- NCT07259655
- Testing
- Ephedrine (6 mg boluses), Norepinephrine (10 µg boluses)
- Where
- Tunisia
- Volunteers
- 100 people
- Sponsor
- Hopital Charles Nicolle
Hemodynamic Instability, Post-induction Hypotension (PIH)
Preoperative Neutrophil-to-Albumin Ratio and Post-Induction Hemodynamic Vulnerability in Major Oncologic Surgery
This prospective observational study aims to evaluate whether the preoperative neutrophil percentage-to-albumin ratio (NPAR) is associated with post-induction hemodynamic vulnerability in adult patients undergoing elective major…
- Trial name
- NCT07804706
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Hypotension After Spinal Anesthesia
Lingual Ondansetron in Reduction of Spinal Hypotension in Cesarean Section
The goal of this clinical trial is to learn if drug ondansetron, used in lingual form, lowers the incidence of spinal anesthesia-induced hypotension in cesarean sections. It will also learn about the safety of drug ondansetron.
- Trial name
- NCT07037654
- Testing
- ondansetron lingual film
- Where
- Egypt
- Volunteers
- 112 people
- Sponsor
- Suez Canal University
Post-induction Hypotension, Lidocaine
Lidocaine-based Versus Opioid-based Induction of Anesthesia in Emergency Laparotomy
Lidocaine-based anesthesia had been recently reported as a successful regimen for induction of anesthesia in elderly population with better hemodynamic profile than opioid-based induction.
- Conditions
- Post-induction Hypotension, Lidocaine, Opioid, Emergency Laparotomy
- Trial name
- NCT06772727
- Testing
- Lidocaine, Fentanyl, Propofol
- Where
- Egypt
- Volunteers
- 149 people
- Sponsor
- Cairo University
Hypotension on Induction
Carotid Artery Corrected Flow Time and Respiratory Variation of Blood Flow Peak Velocity for Prediction of Hypotension After Induction of General Anaesthesia in Adult Patients With Chronic Liver Disease
Baseline Measurements For the ultrasound parameters, it is the average of three readings In supine position . The investigators will continuously monitoring during induction and 10 minutes after.
- Trial name
- NCT07370103
- Where
- Egypt
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hypotension on Induction, Cardiac Surgery
The Impact of Multiple Antihypertensive Therapy on Post-Induction Hypotension Burden in Cardiac Surgery Patients
This study aims to investigate the impact of multiple preoperative antihyperstensive drug use on the burden of post-induction hypotension (PIH) in patients undergoing elective cardiac surgery.
- Conditions
- Hypotension on Induction, Cardiac Surgery, Antihypertensive Agents, Anesthesia, Intravenous
- Trial name
- NCT07541222
- Testing
- Chronic Antihypertensive Medication Use
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Konya City Hospital
Post-induction Hypotension (PIH), Geriatric Patient
Incidence and Risk Factors of Post-Induction Hypotension in Geriatric Cancer Patients
This observational clinical study aims to investigate the incidence and risk factors of post-induction hypotension (PIH) in geriatric cancer patients undergoing surgery under general anesthesia.
- Conditions
- Post-induction Hypotension (PIH), Geriatric Patient, Oncologic Disease, Hemodynamic Effects of General Anesthesia
- Trial name
- NCT07294040
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Dolunay ARIK
Anesthesia
A Study of Changes in Heart Function and Blood Flow in People Receiving Anesthesia
The purpose of this study is to understand changes in heart function (how the heart pumps blood) and blood flow in people who receive general anesthesia during surgery.
- Trial name
- NCT05954832
- Testing
- Echocardiography
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Hypotension During Surgery
Electrical Acupoint Stimulation Reduces Intrathecal Anesthesia Induced Hypotension
The parturients may suffer from hypotension after spinal anesthesia and the incidence could be as high as 70-80% when pharmacological prophylaxis is not used.
- Trial name
- EARTH (NCT05724095)
- Testing
- high frequency acupoint stimulation, low frequency acupoint stimulation, electrodes attached
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Zhihong LU
Hypotension on Induction
Arterial Waveform Analysis for Predicting Post-induction Hypotension
The goal of this observational study is to develop a computation model for accurately predicting post-induction hypotension in patients receiving laparoscopic surgery under general anesthesia.
- Trial name
- NCT05756933
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Taipei Medical University
General Anesthesia, Hypotension on Induction
Ultrasonographic Predictors of Hypotension After Induction
The purpose of the study is to evaluate the predictive value of the inferior vena cava collapsibility index and caval aorta index for detecting hypotension after induction of general anesthesia.
- Trial name
- NCT05239234
- Testing
- Inferior vena cava-Aorta diameter index
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Antalya Training and Research Hospital
Flow Time, Carotid Doppler Ultrasound
Carotis cFT In Prediction Of Hypotension
The aim of our study is to determine the predictive value of pre-anesthesia FTc for hypotension that may develop after general anesthesia induction in patients over 65 years of age and to investigate the correlation between…
- Conditions
- Flow Time, Carotid Doppler Ultrasound, Hypotension, Anesthesia
- Trial name
- NCT05896514
- Testing
- ultrasound-guided carotid artery flow time measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Secondary Peritonitis, Post-induction Hypotension
Low-dose Norepinephrine Infusion for Prevention of Post-induction Hypotension in Emergency Surgery for Peritonitis
This study tests whether giving a low-dose norepinephrine infusion just before induction of anesthesia can reduce low blood pressure during emergency surgery for peritonitis.
- Trial name
- NCT07529795
- Testing
- Norepinephrine (0.05 μg/kg/min)
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Bach Mai Hospital
Norepinephrine, Post-induction Hypotension
Determination of the ED50 and ED95 of Prophylactic Norepinephrine Infusion for Preventing Post-induction Hypotension in Elderly Patients Undergoing Major Abdominal Surgery
The goal of this clinical trial is to determine the ED50 and ED95 of prophylactic norepinephrine infusion for preventing post-induction hypotension in elderly patients undergoing major abdominal surgery using up-and-down…
- Trial name
- NCT05637164
- Testing
- norepinephrine bitartrate
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Elderly Patients Undergoing Elective Non-cardiac Surgery
Ultrasound of the Inferior Vena Cava in the Prevention of Hypotension After Induction of General Anesthesia
Based on the preoperative ultrasound detection of various parametric indicators of the inferior vena cava cross-section, including the ratio of the inferior vena cava's long and short axes, cross-sectional area and circumference…
- Trial name
- NCT06530901
- Testing
- Multidimensional ultrasound of the inferior vena cava
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhuan Zhang
Hypotension
Hypotension After Anesthetic Induction with Remimazolam in Elderly
Even though remimazolam is known to be safely administered without hemodynamic instability, hypotension is the one of the common side effects of remimazolam.
- Trial name
- NCT05538741
- Testing
- Bolus of remimazolam, Continuous infusion of remimazolam
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- Kangbuk Samsung Hospital
IVC Collapsibility Index as Predictor for Hypotension
Inferior Vena Cava Collapsibility Index and Caval Aorta Index for Prediction of Hypotension General Anaesthesia
1. To estimate sensitivity and specificity of preoperative IVCCI, max aortic diameter and IVC:Ao index as predictors of hypotension after induction of general anesthesia. 2.
- Trial name
- NCT05368363
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Hypotension, General Anesthesia Induced Hypotension
Perfusion Index-derived Parameters as Predictors Post-induction Hypotension.
The perfusion index (PI) is a numerical value for the ratio between pulsatile and non-pulsatile blood flow measured by a special pulse oximeter.
- Trial name
- NCT04217226
- Testing
- Perfusion index derived parameters
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Cairo University