Clinical trials: Polytrauma, active
Polytrauma Patients
Predictive Value of Revised Trauma Score(RTS)and Glasgow Coma Scale (GCS)of Mortality in Patients with Multiple Trauma.
This study aims to assess the efficacy of RTS and GCS in predicating the mortality among multiple trauma patients admitted to emergency departments at Assiut university hospital.Which score is better in predicting mortality in…
- Trial name
- NCT06737874
- Volunteers
- 100 people
- Sponsor
- Assiut University
Fractures, Bone, Fracture Multiple
MDR - Biomet Cannulated Screws
The objective of this retrospective enrollment/prospective follow up study is to collect data confirming safety, performance, and clinical benefits of the Biomet Cannulated Bone Screw System (Implants and Instrumentation) when…
- Trial name
- NCT04002518
- Testing
- Biomet Cannulated Screw: 3.0, 4.0, 5.0, 6.5, and 8.0mm screws.
- Where
- 3 sites in United States
- Volunteers
- 51 people
- Sponsor
- Zimmer Biomet
Polytrauma, Resuscitation, Trauma Patients
Pv-aCO₂ Gap-Guided Resuscitation in Adult Polytrauma Patients: A Prospective Randomized Controlled Trial
dult patients with multiple traumatic injuries admitted to the ICU from the operating room, emergency department, or hospital wards who meet the study criteria will be included after obtaining informed consent from the patient or…
- Trial name
- NCT07480655
- Testing
- Veno-arterial Carbondioxide gap, Conventional resuscitation end points
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Pakistan Institute of Medical Sciences
Trauma Injury, Trauma, Multiple
Effectiveness of a Self-management Program After Traumatic Injury
Traumatic injuries, defined as a physical injury with sudden onset, are a leading cause to disability and impaired health. Persons who sustain a traumatic injury often report problems in daily life activities and reduced quality…
- Conditions
- Trauma Injury, Trauma, Multiple, Polytrauma
- Trial name
- SEMPO (NCT06305819)
- Testing
- self-management support program, Control group
- Where
- Norway
- Volunteers
- 220 people
- Sponsor
- Oslo University Hospital
Polytrauma
Comparing Exponential Injury Severity Score (EISS) With Injury Severity Score (ISS) and New Injury Severity Score (NISS)
Trauma is defined as a physical injury from an external source of sudden onset and severity, which require immediate medical attention.
- Trial name
- NCT06653816
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Assiut University
Stroke, Acquired Brain Injury
Machine Learning to Predict Factors Affecting Rehabilitation Length of Stay and Healthcare Costs for Neurological Rehabilitation
The aim of this retrospective study is to ascertain total direct costs, rehabilitation length of stay (RLOS) and factors associated with RLOS for neurological inpatient rehabilitation at the tertiary care hospital.
- Conditions
- Stroke, Acquired Brain Injury, Traumatic Brain Injury, Brain Tumor
- Trial name
- NCT06704997
- Where
- Singapore
- Volunteers
- 10,000 people
- Sponsor
- Tan Tock Seng Hospital
Exanguination, NCTH
Abdominal Aortic Junction Tourniquet (AAJT-S) for Non-compressible Torso Haemorrhage
This study seeks to evaluate the feasibility of a Abdominal Aortic Balloon Occlusion of the Aorta (AAJT-S) in exanguinating trauma patients with non-compressible truncal haemorrhage in the emergency room and the pre-hospital…
- Conditions
- Exanguination, NCTH, Polytrauma
- Trial name
- NCT06622317
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- Medical University of Graz
Polytrauma Patients
Correlation Between Inferior Vena Cava Collapsibility Index and Serum Lactate in Poly-trauma Patients
Polytrauma is defined as the presence of multiple traumatic injuries that may cause systemic physiological derangements and life-threatening conditions.
- Trial name
- NCT07255456
- Testing
- Abdominal ultrasound and Serum Lactate Level
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Farid Esmael Haridy Mohamed
Insomnia Disorder, Mild Traumatic Brain Injury
Sleep MAPP in the Polytrauma/TBI System of Care
This pilot implementation trial will evaluate the Sleep Disorder Management Assistance for Providers and Patients (Sleep MAPP) Care Pathway in one Veterans Health Administration Polytrauma/TBI System of Care clinic.
- Trial name
- Sleep MAPP (NCT07886398)
- Testing
- Sleep MAPP Care Pathway
- Where
- 2 sites in United States
- Volunteers
- 900 people
- Sponsor
- VA Office of Research and Development
Polytrauma
Prognostic Value of Capillary Lactatemia in Potentially Severe Polytrauma Patients
Nowadays, the tools available to assess the severity of a polytrauma patient in the pre-hospital setting (vital parameters, shock index, MGAP score, Vittel criteria) have their limitations and are sometimes subjective.
- Trial name
- CLAT (NCT06969404)
- Testing
- capillary blood sampling
- Where
- 3 sites in France
- Volunteers
- 550 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Spinal Cord Injuries, Polytrauma
Conditioning & Open-Label Placebo (COLP) for Opioid Management in Intensive Inpatient Rehabilitation
The use of the conditioning open-label placebo (COLP) paradigm will be studied as a dose extension method to lower opioid dosage in patients with spinal cord injury, polytrauma, and burn injury.
- Conditions
- Spinal Cord Injuries, Polytrauma, Burns
- Trial name
- NCT05351333
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Spaulding Rehabilitation Hospital
Traumatic Brain Injury, Post-traumatic Stress Disorder
Improving Sleep in Veterans With the Polytrauma Clinical Triad
The "polytrauma clinical triad" (PCT), a highly disabling constellation of factors, is defined by the coexistence of traumatic brain injury, post-traumatic stress disorder, and chronic pain.
- Conditions
- Traumatic Brain Injury, Post-traumatic Stress Disorder, Chronic Pain
- Trial name
- LIONv2 (NCT06477796)
- Testing
- Morning Bright Light Therapy, Negative Ion Generator
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- VA Office of Research and Development
Delirium, Cognitive Impairment
Illuminating Neuropsychological Dysfunction and Systemic Inflammatory Mechanisms Gleaned After Hospitalization in Trauma-ICU Study
Cognitive skills are essential to live independently, manage finances, maintain employment, and function in society. Loss of these cognitive skills puts a tremendous burden on society as seen with dementias, Alzheimer's disease…
- Conditions
- Delirium, Cognitive Impairment, Alzheimer; Early Onset, Trauma
- Trial name
- INSIGHT-ICU (NCT03098459)
- Testing
- Non-interventional observational prospective cohort study
- Where
- United States
- Volunteers
- 432 people
- Sponsor
- Vanderbilt University Medical Center
PTSD - Post Traumatic Stress Disorder
First-Line Intervention for PTSD - Intensive Treatment
The goal of this clinical trial is to learn if an intensive program can treat post-traumatic stress disorder (PTSD) in adults getting treatment for the first time, and whether it has lower societal costs.
- Trial name
- FLIP-IT (NCT06700590)
- Testing
- Intensive Treatment, Treatment as usual
- Where
- 4 sites in Netherlands
- Volunteers
- 186 people
- Sponsor
- ARQ National Psychotrauma Centre
Trauma, Trauma Injury
Whole Blood in Trauma Patients With Hemorrhagic Shock
This study aims to evaluate among trauma patients with hemorrhagic shock the clinical impact of hemostatic resuscitation between whole blood vs.
- Conditions
- Trauma, Trauma Injury, Trauma, Multiple
- Trial name
- WEBSTER (NCT05634109)
- Testing
- Transfusion of blood products
- Where
- Colombia
- Volunteers
- 220 people
- Sponsor
- Fundacion Clinica Valle del Lili
Trauma, Multiple
Mortality Prediction Using Trauma Scores
The goal of this prospective cohort study is to compare the predictive utility of the Injury Severity Score (ISS), New Injury Severity Score (NISS), Revised Trauma Score (RTS), and Trauma and Injury Severity Score (TRISS) in…
- Trial name
- NCT06709547
- Where
- Iraq
- Volunteers
- 150 people
- Sponsor
- Al-Nahrain University
Orthopaedic Trauma, Chronic Opioid Use
Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma Patients
The goal of this randomized clinical trial is to learn if the use of a low-dose nonsteroidal anti-inflammatory drug (NSAID), ketorolac, reduces the rate of chronic opioid use in orthopaedic trauma patients.
- Trial name
- NCT06201676
- Testing
- Ketorolac Injection, Standard of Care (SOC) Multimodal Analgesia
- Where
- 2 sites in United States
- Volunteers
- 458 people
- Sponsor
- Massachusetts General Hospital
Patient Reported Outcome Measures, Recovery of Function
FIT Study (Functional Outcomes In Trauma Study)
Why? There is not much information in the UK on how well patients who sustain major trauma function afterwards. Major trauma is defined as significant injuries with a calculated 'injury severity score' (ISS) over 15.
- Conditions
- Patient Reported Outcome Measures, Recovery of Function, Rehabilitation, Disability Evaluation
- Trial name
- NCT04074382
- Testing
- Online Questionnaires, Qualitative Interviews
- Where
- United Kingdom
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Abdominal Injuries, Wounds and Injuries
Predictors of In-Hospital Mortality in Severe Abdominal Trauma
Severe abdominal trauma is a leading cause of early death from bleeding and of later death from sepsis and organ failure. Clinicians use scoring systems to estimate the risk of dying, but most of these scores were developed and…
- Conditions
- Abdominal Injuries, Wounds and Injuries, Wounds, Nonpenetrating, Wounds, Penetrating
- Trial name
- NCT07843628
- Where
- Egypt
- Volunteers
- 430 people
- Sponsor
- Minia University
Trauma, Multiple, Trauma
Swiss Trauma Registry
The Swiss Conference of Cantonal Health Directors has transferred the planning of highly specialized medicine to a specialized body under the direction of the Swiss Academy of Sciences.
- Trial name
- NCT03526029
- Where
- 12 sites in Switzerland
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Basel, Switzerland