Clinical trials: Polyphenol
Nutrition, Absorption
Bioavailability From Chickpea Meals in Ileostomists?
The matrix of a food can significantly affect how well humans can absorb and use nutrients. Plants like fruits, vegetables, nuts, grains, and legumes have cell walls that form a network around their cells.
- Conditions
- Nutrition, Absorption, Polyphenolic Compounds and Metabolism, Polyphenols Absorption Profile
- Trial name
- NCT06921811
- Testing
- Intact chickpeas, Broken chickpeas
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Type II Diabetes Mellitus
Effects of a Spiced Meat Patty on Inflammation in Men With Type 2 Diabetes
Polyphenols belong to the largest group of secondary metabolites produced by plants, mainly, in response to biotic or abiotic stresses such as infections, wounding, UV irradiation, exposure to ozone, pollutants, and other hostile…
- Trial name
- NCT01076829
- Testing
- Spice polyphenols
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Anemia, Low Iron Stores
Improving Iron Status Through Consumption Of Iron Fortified Cowpea: An Intervention Study
Rationale: Iron deficiency and zinc deficiency, are of public health significance in sub-Saharan Africa. An estimated 50% of children (5-14 years) in developing countries suffer from anaemia, half of which is estimated iron…
- Trial name
- NCT01208363
- Testing
- Cowpea fortified with NaFeEDTA, in form of Toubani.
- Where
- Ghana
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Blood Glucose
A Pilot Study Evaluating Oat Polyphenols on Post-prandial Glucose Response
The trial will use a two period acute double-blind cross-over design to compare the effects of a serving of oatmeal containing high or low amounts of avenanthramides (AV) on post-prandial blood glucose response in healthy adults.
- Trial name
- NCT04260425
- Testing
- Serving of oatmeal made from low avenanthramides oats and water, Serving of oatmeal made from high avenanthramides oats and water
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Healthy
Effect of Consumption of a Novel Functional Yogurt on Blood Biomarkers of Healthy Participants
The purpose of the study is to assess the effect of a dietary intervention that includes the consumption of a novel functional yogurt (enriched with probiotics and polyphenols) on the blood biomarkers of healthy participants.
- Trial name
- FB-CL1 (NCT05612243)
- Testing
- Consumption of a meal with yogurt enriched with probiotics immobilized on oat flakes and polyphenols, Consumption of a meal with yogurt enriched with probiotics immobilized on oat flakes, Consumption of a meal with plain Yogurt with oat flakes
- Where
- Greece
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- ANTONIOS KOUTELIDAKIS
Type II Diabetes
The Effects of Raspberry Leaf Tea on Blood Glucose Control
The aim of the present clinical trial is to assess how raspberry leaf polyphenols impact on postprandial glucose and insulin levels in healthy individuals consuming sucrose.
- Trial name
- RLT (NCT06385626)
- Testing
- Raspberry leaf tea
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Reading
Exercise Capacity
The Effect of Sweet Orange and Pomegranate Extract Supplementation on Exercise Capacity in Middle-aged Adults
The aim of the present study is to investigate the effect of 12-week long daily administration of a sweet orange and pomegranate extract on exercise capacity in healthy adults.
- Trial name
- Actiful2 (NCT05133778)
- Testing
- Sweet orange and pomegranate extract, Maltodextrin control
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Hyperglycaemia
Effects of Polyphenols Found in Pomegranate and Olives Food Supplements on Postprandial Blood Glucose in Vivo.
Consumption of carbohydrate containing foods or sugary drinks brings about changes to the blood glucose levels. After a meal or drink, blood glucose rises until it reaches a peak concentration usually after 30 minutes.
- Trial name
- NCT02486978
- Testing
- Control (109 g white bread), Dose 1, Dose 2
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Bioavailability
Impact of the Source and Food Matrices on the Bioavailability of Peptan® (Collagen Peptides) in Healthy Subjects
The aim of this study is the comparison of the oral bioavailability of hydroxyproline, a key marker for collagen peptide intake, after ingestion of collagen peptides from different sources, sizes and together with different food…
- Trial name
- NCT04097808
- Testing
- collagen peptides
- Where
- Germany
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Rousselot BVBA
Healthy
The Effect of Short-term Supplementation of OliPhenolia® on Fat Oxidation
There is current research interest in the use of fruit and plant-based food products containing high levels of natural antioxidants and their impact on exercise, which may be particularly beneficial for recreationally or…
- Trial name
- NCT07210099
- Testing
- Concentrated olive fruit water, Anhydrous caffeine
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Anglia Ruskin University
Inflammation
Suppression of Postprandial Monocyte Activation by Blueberries or Docosahexaenoic Acid in Humans
The overall goal of the research study is to determine whether a high-fat meal causes postprandial (after meal) inflammation, and whether eating n-3 polyunsaturated fatty acids (PUFAs) or blueberries that are rich in…
- Trial name
- NCT02472171
- Testing
- High saturated fat meal, blueberry powder and sunflower oil
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Obesity, Diabetes
Effect of Pomegranate Extract Intake on Body Composition and Blood Pressure.
Pomegranate has gained widespread popularity since the health effects of the whole fruit, as well as its juices and extracts, have been studied in relation to a variety of chronic conditions such as hypertension, diabetes…
- Conditions
- Obesity, Diabetes, Cardiovascular Disease
- Trial name
- NCT02017132
- Testing
- Pomegranate extract
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
Hypercholesterolemia
Effect of Oleactiv® on LDL Oxidability
Oleactiv® have previously demonstrated beneficial effects in an animal model of diet-induced atherosclerosis. After a 12-week supplementation, a substantial reduction of aortic fatty streak area has been observed.
- Trial name
- e-POL (NCT05221346)
- Testing
- Plant food supplement, Maltodextrin
- Where
- France
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Lille
Skin Ageing
Effect of Pomanox® on Skin Ageing (POMASKIN)
The state of skin health impacts not only on the general health of individuals, but also on mental health. Ultraviolet radiation (UV) is one of the main external factors that causes skin ageing, producing photo-aging…
- Trial name
- POMASKIN (NCT05842447)
- Testing
- 367 mg Pomanox group, 700 mg Pomanox group, Control group
- Where
- 2 sites in Spain
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Fundació Eurecat
Intestinal Functional Disorder, Inflammation
The Antagonistic Effect of Composite Polyphenols on Health Damage Caused by Environmental Pollutants
The study attempts to conduct randomized controlled trials to understand whether daily exposure to environmental pollutants can cause harm to human health, explore whether the intake of composite polyphenols can alleviate…
- Trial name
- NCT06437119
- Testing
- Compound plant nutrients
- Where
- China
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Fudan University
Insulin Resistance
Effect of Dietary Polyphenols on Insulin Sensitivity
A large and growing segment of the population is prediabetic. Dietary interventions that improve insulin sensitivity may be important in preventing the progression to full-blown diabetes in these individuals.
- Trial name
- NCT00668928
- Testing
- Polyphenols (flavon-3-ol monomers and oligomers)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- United States Department of Agriculture (USDA)
Inflammation
Flavonoid-rich Supplement Influence on the Human Metabolome
This study will measure the effect of ingesting a flavonoid-rich supplement on various biomarkers in overweight/obese women during a 12-week period.
- Trial name
- NCT03004742
- Testing
- Flavonoid
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Polyphenols, Cardiovascular Diseases
Autonomic and Cardiovascular Recovery After the Acute Use of Resveratrol in Overweight and Obesity Individuals
The aim of this study is to understand the importance of resveratrol supplementation as a possible adjuvant in improving the metabolic profile and cardiovascular autonomic recovery of individuals with overweight and grade I…
- Conditions
- Polyphenols, Cardiovascular Diseases, Autonomic Nervous System
- Trial name
- Resveratrol (NCT06020313)
- Testing
- Resveratrol Experimental
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Taisy Cinthia Ferro Cavalcante
Inflammation
Effect of a Single Dose of Cranberry Beverage on Inflammation and Oxidative Stress
The purpose of this study is to determine the effects of a single dose of cranberry beverage in healthy adults on the kinetic uptake of polyphenol compounds and polyphenol metabolites, and antioxidative and anti-inflammatory…
- Trial name
- NCT01780922
- Testing
- Low Calorie Cranberry Juice Cocktail, Cranberry Extract Beverage, Non-Cranberry Beverage
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Washington State University
Healthy Volunteers
Grape Polyphenol Kinetics in Humans
The objectives of this study are the following: 1) to confirm that the administration of grape juice, resveratrol, and grape seed polyphenol extract results in a similar plasma and urinary metabolic profile in aged humans…
- Trial name
- NCT01751750
- Testing
- Grape
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Janet Novotny