Clinical trials: Polypectomy
Colonic Polyps
Cold Snare,Hot Snare and APC Polypectomy for the Complete Removal of Small Left Sided Colon Polyps
Given the limited existing data regarding the advantages and limitations of the existing techniques in the removal of colonic polyps the investigators designed a prospective study in order to compare cold snare vs hot snare vs…
- Trial name
- NCT02479893
- Testing
- polypectomy
- Where
- Greece
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Evangelismos Hospital
Colo-rectal Cancer, Polyp of Colon
Evaluation of Cold Forcep and Cold Snare Polypectomy for Polyps Less Than or Equal to 3mm in Size During Colonoscopy
The focus of the study is to evaluate impact of cold forcep and cold snare in achieving complete resection during polypectomy of polyps <=3mm during colonoscopy.
- Conditions
- Colo-rectal Cancer, Polyp of Colon, Adenomatous Polyp of Colon
- Trial name
- NCT04551001
- Testing
- Cold forcep polypectomy, Cold snare polypectomy
- Where
- United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Stanford University
Transcervical Resection of Endometrium, Transcervical Resection of Fibroids
Comparing Two Types of Sedation to Gynaecological Patients
The primary endpoint is to investigate the difference in pain between patients who receive deep sedation with spontaneous breathing versus patients who receive general anesthesia.
- Conditions
- Transcervical Resection of Endometrium, Transcervical Resection of Fibroids, Transcervical Resection of Polyp
- Trial name
- NCT01412632
- Testing
- Remifentanil, propofol and citanest
- Where
- Denmark
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Procedural Bleeding, Delayed Bleeding
A Comparison of Eleview Versus Hetastarch as Injectate for EMR
EMR is a technique used for the removal of flat or sessile neoplasms confined to the superficial layers of the GI tract using a snare.
- Conditions
- Procedural Bleeding, Delayed Bleeding, Post-Polypectomy Syndrome, Post Procedural Complication
- Trial name
- NCT03350217
- Testing
- Eleview, Hetastarch
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Indiana University
Adenomatous Polyps
A Comparison of the Resection Rate of Cold Snare Polypectomy for Large (10-15 mm) and Small (5-9 mm) Colorectal Polyps
Colorectal cancer remains the third most common cause of death from cancer worldwide. Colonoscopy allows removal of adenomatous polyps is the best colorectal cancer screening, according to the adenoma-carcinoma sequence.
- Trial name
- CSP (NCT03647176)
- Testing
- Cold snare polypectomy
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Yuqi He
Colorectal Adenoma, Colorectal Polyp
Validation of the Global Polypectomy Assessment Tool (GPAT)
Colorectal polypectomy is offten incompletely performed with high variability between endoscopists, resulting in interval cancer or repeated procedures.
- Conditions
- Colorectal Adenoma, Colorectal Polyp, Colo-rectal Cancer
- Trial name
- GPAT (NCT05877456)
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Colorectal Cancer, Colorectal Polyp
Predicting Risk for Post-polypectomy Colorectal Cancer
This originated as an observational study of Kaiser Permanente Northern California (KPNC) patients with a history of adenoma diagnosed by colonoscopy who received a subsequent surveillance colonoscopy between 2014 and 2019.
- Conditions
- Colorectal Cancer, Colorectal Polyp, Colorectal Adenoma, Neoplasm, Colorectal
- Trial name
- PREDICT (NCT05606081)
- Testing
- Logistic regression risk model
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Colorectal Polyp, Colorectal Cancer
Detection of Endoscopic Resection Scars and Delineation of Recurrence is Trainable
Colorectal cancer is prevented by colonoscopy and polypectomy. Failure to recognize the endoscopic resection scar after Endoscopic Mucosal Resection (EMR) risks unrecognized recurrent or residual adenoma (RRA), which may…
- Trial name
- SCAR (NCT06193356)
- Testing
- Learning tool
- Where
- Belgium
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Colorectal Polyp
Assessment of Endoscopic Tip Control Using a Novel Score Based on the Snare Tip Soft Coagulation of Polypectomy Margin Defects
Colorectal cancer is the third most common malignancy worldwide and the second leading cause of cancer related death with approximately 880 792 deaths every year (9,2% of the global yearly 9.6 million cancer deaths).
- Trial name
- NCT05660317
- Testing
- Tip control score
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Polyp Resection Adequacy
Colorectal Polyp Resection Adequacy
The purpose of this study is to determine the best way to ensure that polyps are completely removed by evaluating the borders of the removed polyp.
- Trial name
- NCT02217085
- Where
- United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Endometrial Polyps
Endometrial Polypectomy Performed With Bipolar Electrode Versapoint vs Microscissors or Graspers
Hysteroscopy today is considered the gold standard for the diagnosis and treatment of endometrial polyps. Several hysteroscopic systems to resect endometrial polyps are currently available.
- Trial name
- NCT02590666
- Testing
- Bipolar Polypectomy, Mechanical Polypectomy, Bipolar electrode
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Colorectal Adenoma, Colorectal Lesions
Cold Snare Versus Cold Forceps Polypectomy for Small Lesions
The goal of this clinical trial is to compare the efficacy and the safety of a new device for cold forceps polypectomy (CFP)- a special jumbo forceps- to cold snare polypectomy (CSP) for small colorectal lesions, without adding…
- Trial name
- Cold-SNAPS (NCT06970808)
- Testing
- Sampling from the resection margins
- Where
- Italy
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Azienda USL Modena
Colorectal Cancer, Colorectal Neoplasms
Early Detection of Advanced Adenomas and Colorectal Cancer
This study aims to develop a highly sensitive, specific, and cost-effective blood assay for early detection of colorectal adenomas and cancer, using advanced machine learning and state-of-the-art biological analyses.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Colorectal Polyp, Colorectal Adenocarcinoma
- Trial name
- AACRC (NCT06342440)
- Testing
- DENEB
- Where
- 6 sites in United States, China and 3 more
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Colon Cancer, Colon Polyp
Quad Resection (Hot Snare vs Cold Snare vs Hot EMR vs Cold EMR)
The study will compare the use of cold snare, hot snare, cold EMR, and hot EMR for polyp resection. Although previous studies have compared two of the potential resection methods, no previous study has evaluated all four of the…
- Conditions
- Colon Cancer, Colon Polyp, Colon Adenoma
- Trial name
- NCT03462706
- Testing
- Cold Snare, Hot Snare, Cold EMR
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Indiana University
Bleeding Complication During Colon Polypectomy
Postpolypectomy Bleeding in Patients With Antiplatelet Therapy
The purpose of this study is to determine if the use of aspirin prior to colonoscopy increases the risk of post polypectomy bleeding.
- Trial name
- NCT01465256
- Testing
- Aspirin
- Where
- South Korea
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Soonchunhyang University Hospital
Polyps
Thin Wire Versus Thick Wire Snare for Cold Snare Polypectomy of Diminutive Polyps
Cold snare polypectomy (CSP) is now common practice and has proven to be a safe and effective technique for removal of diminutive polyps. Both thick and thin wire snares are now commonly used for CSP.
- Trial name
- NCT02581254
- Testing
- Thin Wire Snare, Thick Wire Snare
- Where
- Australia
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Western Sydney Local Health District
Large Polyps in the Gastrointestinal Tract
Evaluation of Blood as a Submucosal Cushion During Endoscopic Polypectomy and Mucosal Resection
For removal of large flat lesions of the gastro-intestinal tract injection of a solution under the lesion creates a "safety" cushion and protects from damage to the gastrointestinal tract wall.
- Trial name
- NCT00583466
- Testing
- Autologous blood injection, Normal saline, HPMC
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Polyp Colorectal, Endoscopic Mucosal Resection
Structured TXI-RDI Integration for Endoscopic Resection
The goal of this clinical research study is to learn whether two advanced imaging tools, called Texture and Color Enhancement Imaging (TXI) and Red Dichromatic Imaging (RDI), can make the removal of large colon polyps safer…
- Trial name
- STRIkER (NCT07474844)
- Testing
- Texture and Color Enhancement Imaging (TXI) and Red Dichromatic Imaging (RDI), High Definition White Light Endosocopy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Colorectal Cancer, Colorectal Polyp
Accuracy for Predicting Deep Submucosal Invasion
The main aim of this study is to determine whether the assessment of the invasive pattern based on NBI with dual focus/magnification or BLI with magnification ± chromoendoscopy (NBI+CE) for predicting deep invasion is…
- Trial name
- NBIBLI (NCT03748667)
- Testing
- White light endoscopy (WLE), NBI/BLI +/- chromoendoscopy (NBIBLI +/- CE)
- Where
- 14 sites in United States, Japan and 1 more
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Surveillance Colonoscopy
Post-polypectomy Surveillance Interval In High-risk Subjects After Screening Colonoscopy
With many countries initiating population colorectal cancer (CRC) screening, including Hong Kong, more robust guidance for surveillance interval is required to maximize subject's benefit with optimal use of resources.
- Trial name
- NCT04034563
- Testing
- 1) Risk of metachronous advanced neoplasia at 3-year, beyond 3 years surveillance colonoscopy
- Where
- 2 sites in Hong Kong
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong