Clinical trials: Point-of-Care Systems
COVID-19 Infection
PREDICT: A PBRN Feasibility Study on COVID-19 Screening in Dental Practice
The study team will conduct a feasibility study to develop and test out procedures for improved triage and COVID-19 testing in dental practices to increase safety and perceptions of the safety of Dental Health Care Workers (DHCW)…
- Trial name
- PREDICT (NCT05123742)
- Testing
- COVID-19 Testing
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Lower Resp Tract Infection
An Algorithm to Decide on Antibiotic Prescription in Lower Respiratory Tract Infection in Primary Care
The study is randomized clustered pragmatic trial whose objective is to decrease unnecessary antibiotic prescription in adult patients with lower respiratory tract infection managed at primary care level in Switzerland, using a…
- Trial name
- UltraPro (NCT03191071)
- Testing
- UltraPro, Procalcitonin, Blood sampling
- Where
- Switzerland
- Volunteers
- 469 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Peripherally Inserted Central Catheters
Point of Care Ultrasound for PICC Line Monitoring Study
A prospective comparative study evaluating chest x-ray determination of PICC line tip location and POC ultrasound PICC line tip location.
- Trial name
- PUP (NCT03954977)
- Testing
- PICC line ultrasound
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Patellofemoral Disorder
Diagnostic POCUS of Patellar Tendinopathy in Female Athletes
Purpose: The purpose of this study is to determine the clinical effectiveness of point-of-care diagnostic ultrasound in the assessment of patellar tendon pathologies
- Trial name
- POCUS (NCT05880277)
- Testing
- POCUS
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Youngstown State University
Anesthesia
Assessment of Diagnostic Adequacy of AI-assisted Point-of-Care Echocardiography Among Anesthesiology Trainees
This pilot study serves to assess the diagnostic adequacy of Artificial Intelligence (AI)-guided point-of-care. Focused echocardiography examinations will be obtained by Anesthesiology trainees and assessed by an expert…
- Trial name
- NCT06548373
- Testing
- Artificial Intelligence-assisted Point-of-Care Echocardiography
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Anaemia
A Trial of 2 'Point of Care' Diagnostic Methods to Improve Detection and Treatment of Anaemia in African Children
A high proportion of children under the age of 5 years and pregnant women in Tanzania is anaemic, particularly in areas of high malaria transmission.
- Trial name
- EARS (NCT00439595)
- Testing
- Hemocue 210 meter, Copack HBCS
- Where
- Tanzania
- Volunteers
- 450 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Influenza-Like Illness, Influenza
Impact of Rapid Flu Testing in BMC ED
The purpose of the study is to compare Emergency Department patients who undergo influenza testing using an FDA-approved point-of-care device (Cobas Liat Influenza A/B assay) located in the ED, to patients whose samples are sent…
- Trial name
- FluProcess (NCT02979730)
- Testing
- Core Lab Test, ED Point of Care Test
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- Boston Medical Center
Hepatitis C
ED Patient's Perceptions and Acceptability Toward a Novel POC HCV Viral Load Testing
Hepatitis C virus (HCV) infection has become the leading fatal infectious disease in the United States. Approximately 75% of individuals who have been infected with HCV are chronically infected with the virus.
- Trial name
- NCT03767231
- Testing
- Xpert HCV Viral Load Finger-stick Point-of-Care test (Cepheid)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Johns Hopkins University
Tricuspid Regurgitation, Mechanical Ventilation Pressure High
Effect of PEEP on TRJV in Mechanically Intubated Pediatric Patients
Prospective observational cohort study within the Pediatric Intensive Care Unit (PICU). We will perform point-of-care-ultrasound (POCUS) to quantify tricuspid regurgitant jet velocity (TRJV) on mechanically ventilated (MV)…
- Conditions
- Tricuspid Regurgitation, Mechanical Ventilation Pressure High, Pediatric Respiratory Diseases
- Trial name
- NCT06229886
- Testing
- Application of positive-end-expiratory pressure
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Haemodialysis, Volume Assessment
Internal Jugular Vein Ultrasound for Volume Status Assessment in Haemodialysis
To Evaluate accuracy of Internal Jugular Vein Point-of-Care ultrasound for volume status evaluation in chronic haemodialysis
- Conditions
- Haemodialysis, Volume Assessment, Point of Care Ultrasound (POCUS)
- Trial name
- IJV-US (NCT07438613)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Bologna
Vulvar Intraepithelial Neoplasia, HPV-Independent, Vulvar Squamous Cell Carcinoma
Evaluation of a Point-of-Care, AI-Powered Spectroscopy Device for Triage of Suspicious Vulvar Lesions: A Pilot Study
This purpose of this study is to assess the feasibility of using the DermaSensor™ device on vulvar skin.
- Conditions
- Vulvar Intraepithelial Neoplasia, HPV-Independent, Vulvar Squamous Cell Carcinoma, Vulvar Squamous Intraepithelial Lesion, HPV-Associated
- Trial name
- NCT07886203
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Emergency Medicine, POCUS
Point-of-Care Ultrasound for Diagnosing Abdominal Pain in the Emergency Department
The goal of this clinical trial is to learn if adding an abdominal ultrasound scan to the standard examination helps emergency physicians make a correct diagnosis in adults with acute abdominal pain in the emergency department.
- Conditions
- Emergency Medicine, POCUS, Abdominal Pain (AP), Acute Abdominal Pain
- Trial name
- AbdoPOCUS (NCT07849569)
- Testing
- Point of care ultrasound
- Where
- 3 sites in Denmark
- Volunteers
- 508 people
- Sponsor
- University of Aarhus
COVID-19, Upper Respiratory Infection
A Noninvasive Multimodal Biosensing Device for Screening and Monitoring Response to Treatment of Infectious Respiratory Diseases
Background: The COVID-19 outbreak has strained the health care system. New tools are needed for diagnostic testing and monitoring of people who have the virus.
- Conditions
- COVID-19, Upper Respiratory Infection, Lower Respiratory Infection
- Trial name
- NCT05035420
- Testing
- Fitbit, Douglas Bag, Periflux 6000 EPOS
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hemorrhagic Shock, Trauma
Inferior Vena Cava Versus Subclavian Vein Collapsibility for Predicting Fluid Responsiveness in Trauma Hemorrhagic Shock
Hemorrhagic shock from severe bleeding is a leading cause of preventable death in trauma patients. Intravenous (IV) fluid resuscitation is essential for stabilizing blood pressure and organ perfusion, but administering too much…
- Conditions
- Hemorrhagic Shock, Trauma, Hypovolemia, Fluid Responsiveness
- Trial name
- NCT07817966
- Volunteers
- 120 people
- Sponsor
- Assiut University
Trauma, Brain, Subarachnoid Hemorrhage
Non-invasive ONSD-based Neuromonitoring in a Neurointensive Care Setting
Intensive care patients with established invasive intracranial neuromonitoring due to neurotrauma are subjected to a repeated non-invasive sonographic recording of the optic-nerve-sheath-diameter (ONSD).
- Conditions
- Trauma, Brain, Subarachnoid Hemorrhage, Intracranial Hypertension
- Trial name
- ONSDDynamics (NCT05818371)
- Testing
- Sonographic determination of the optic nerve sheath diameter
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Tuebingen
Liver Diseases, Liver Cirrhosis
Point-of-care Ultrasound Screening and Assessment of Chronic Liver Diseases and NASH
The main objective of the study is to determine the diagnostic performances of an ultraportable diagnostic ultrasound system for the assessment of liver fibrosis severity in patients with NASH, and to compare them to other…
- Conditions
- Liver Diseases, Liver Cirrhosis, NASH - Nonalcoholic Steatohepatitis, Non-Alcoholic Fatty Liver Disease
- Trial name
- POCUS-NASH (NCT05120557)
- Testing
- Ultrasound liver assessment
- Volunteers
- 1,000 people
- Sponsor
- E-Scopics
Covid19
Leveraging CHWs to Improve COVID-19 Testing and Mitigation Among CJIs Accessing a Corrections-focused CBO
Given the likelihood of COVID-19 remaining an endemic disease among high-risk populations, establishing effective mitigation interventions will be critical to stemming community transmission.
- Trial name
- NCT04878328
- Testing
- Onsite Point-of-care
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Montefiore Medical Center
Neisseria Gonorrheae Infection
Performance, Acceptability, and Usability of a Novel Rapid Lateral Flow Test for Detecting Neisseria Gonorrhoeae in Pregnant and Symptomatic Women Attending Clinics in South Africa.
Previous studies of the Neisseria gonorrhoeae (NG) lateral flow assay (LFA) have shown promising results. In East London, South Africa, the LFA demonstrated a sensitivity of 80% in asymptomatic women.
- Trial name
- GO-SA (NCT07530406)
- Testing
- Novel Lateral Flow Assay for Neisseria gonorrhoeae
- Where
- South Africa
- Volunteers
- 1,239 people, healthy volunteers welcome
- Sponsor
- Foundation for Professional Development (Pty) Ltd
Cardiovascular Diseases, Acute Abdomen
Effectiveness of Point of Care Blood Analysis Obtained From Skin Puncture Blood
This study aimed to evaluate the correlation between the point of care blood analysis obtained from skin puncture blood and conventional blood analysis obtained from venous and arterial blood.
- Conditions
- Cardiovascular Diseases, Acute Abdomen, Respiratory Disease, Renal Disease
- Trial name
- NCT03096665
- Testing
- blood test
- Where
- South Korea
- Volunteers
- 250 people
- Sponsor
- Hanyang University
Extracorporeal Circulation; Complications, Coagulation Disorder
Impact of Cardiac Surgery With a Minimal Invasive Extracorporeal Circuit οn Coagulation: Data From Point of Care Devices
This study includes patients undergoing elective cardiac surgery on MiECC. Coagulation status is assessed with ROTEM (TEM International GmbH, Munich, Germany) and Platelet function with impedance aggregometry using the…
- Conditions
- Extracorporeal Circulation; Complications, Coagulation Disorder, Extracorporeal Circulation of Blood; Thrombocytopenia
- Trial name
- NCT04159064
- Testing
- Thromboelastometry, Impedance Aggregometry
- Where
- Greece
- Volunteers
- 57 people
- Sponsor
- AHEPA University Hospital
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