Clinical trials: Point-of-Care Systems
Outbreaks
Respiratory Outbreak Mitigation in Long-Term Care Using Point-of-Care Testing
Outbreaks of seasonal respiratory viruses can spread rapidly in long-term care homes. Timely results for diagnostic tests remains a challenge for respiratory viruses due to the logistics of using a reference laboratory with…
- Trial name
- PROMPT-LTC (NCT06660433)
- Testing
- Point-of-care respiratory test platform, Existing respiratory virus testing platform
- Where
- 2 sites in Canada
- Volunteers
- 24 people
- Sponsor
- Michael Garron Hospital
Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive
Diagnosing Obstructive Lung Disease With Point of Care Ultrasound
The objective of this study is to evaluate the diagnostic accuracy of Point of Care Ultrasound (POCUS) in identifying obstructive lung diseases (OLDs), using pulmonary function tests (PFTs) as the gold standard for comparison.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive, Asthma, COPD
- Trial name
- NCT06251271
- Testing
- Point-of-Care Ultrasound
- Where
- Israel
- Volunteers
- 301 people
- Sponsor
- Soroka University Medical Center
Syphilis, Syphilis, Congenital
Congenital and Maternal Point of Care Rapid Testing for Syphilis Study, Uganda
Syphilis is an infection which affects about 1 in 25 pregnant women in Uganda. If the infection is not diagnosed and treated this can be a risk to the mother and unborn baby's health.
- Trial name
- COMPARTS (NCT07173764)
- Where
- Uganda
- Volunteers
- 24 people
- Sponsor
- St George's, University of London
Vascular Access
Investigating the Utility of Augmented Reality Assistance for Ultrasound-Guided Vascular Access
This study will investigate the benefits of augmented reality assistance on ultrasound-guided vascular access. Using the Microsoft HoloLens 2 headset, the investigators will study the benefits of augmented reality technology as a…
- Trial name
- NCT07208071
- Testing
- Augmented reality headset use
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Alabama at Birmingham
COVID-19
A Randomized Controlled Trial of a Digital, Self-testing Strategy for COVID-19 Infection in South Africa.
As the world opens up to rapidly increasing vaccination coverage and newer variants, there is an even greater need for timely access to at-home COVID-19 testing, or self-testing based out of kiosks, offices, or private spaces.
- Trial name
- NCT05436795
- Testing
- Abbott Panbio rapid antigen self-tests, COVIDSmart CARE! app
- Where
- South Africa
- Volunteers
- 600 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Heart Diseases
POC - Transfusion Algorithm Cardiac Study
This multi-centre study will provide sound, generalizable data on the effectiveness of a POC-based algorithm to determine to what extent this guideline can reduce blood product transfusions.
- Trial name
- TACS (NCT02200419)
- Testing
- POC-based transfusion algorithm
- Where
- 12 sites in Canada
- Volunteers
- 7,402 people
- Sponsor
- University Health Network, Toronto
Diabetes
Point-of-Care Glucose Testing and Insulin Supplementation
Capillary point-of-care (POC) testing is advocated as a valuable aid in the management of diabetes and hyperglycemia in the hospital setting.
- Trial name
- POC (NCT01702311)
- Testing
- Bedtime insulin Aspart (Novolog)
- Where
- 2 sites in United States
- Volunteers
- 235 people
- Sponsor
- Emory University
Communicable Disease, COVID-19
COVID-19 Diagnostic Self-testing Using Virtual Point-of-care
The goal of the research is to assess candidate COVID-19 rapid diagnostic tests (e.g. immunodiagnostic antibody tests, like Cellex qSARS-CoV-2 IgG/IgM Rapid Test, or antigen tests, like Turklab Test-It COVID-19 Home Test, AllBio…
- Conditions
- Communicable Disease, COVID-19, Sars-CoV2, Infectious Disease
- Trial name
- NCT04348864
- Testing
- COVID-19 Antigen/Antibody Rapid Testing, mobile device image capture and telemedicine support, Telemedicine
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Neuroganics LLC
Ultrasound, Nasogastric Tube
Diagnostic Accuracy of Using Point-of-care Ultrasonography for Confirming Nasogastric Tube Placement
A prospective observational diagnostic study will be conducted to assess the sensitivity and specificity of ultrasound in verifying the correct nasogastric tube placement, using X-ray as the reference standard.
- Conditions
- Ultrasound, Nasogastric Tube, Nasogastric Tube Placement
- Trial name
- NCT06821737
- Testing
- Diagnostic ultrasound, Diagnostic X-ray
- Where
- Hong Kong
- Volunteers
- 675 people
- Sponsor
- Pamela Youde Nethersole Eastern Hospital
Abdominal Aortic Aneurism, Abdominal Aortic Rupture
Haemostasis Management of Abdominal Aortic Procedures
Comparative study on efficacy of haemostatic therapy guided either by standard laboratory coagulation parameters or point-of-care testing in patients undergoing vascular surgical procedures.
- Conditions
- Abdominal Aortic Aneurism, Abdominal Aortic Rupture, Perioperative/Postoperative Complications, Surgical Blood Loss
- Trial name
- NCT03426839
- Testing
- Coagulation tests
- Volunteers
- 40 people
- Sponsor
- University of Pecs
Bacterial Infections
Personalized Antibiotic Therapy - Point-of-Care Determination of Blood Levels of Beta-Lactam Antibiotics Using Coated-Blade-Spray Ion Mobility Spectrometry
A new analytical method for determining beta-lactam antibiotic concentrations in the blood of intensive care patients is to be evaluated.
- Trial name
- CBS-IMS (NCT07666230)
- Volunteers
- 200 people
- Sponsor
- Dr. T. Perl
Pulmonary Aspiration of Gastric Contents, Emergency Surgery
Gastric Ultrasound for Airway Management in Emergency Patients
This prospective observational cohort study evaluates the association between gastric residual content and volume, assessed by point-of-care gastric ultrasound (PoCUS), and the choice of airway management technique (Rapid…
- Conditions
- Pulmonary Aspiration of Gastric Contents, Emergency Surgery, Gastric Residual Volume, Airway Management
- Trial name
- NCT07640165
- Testing
- Preoperative Gastric Point-of-Care Ultrasound (PoCUS)
- Where
- Indonesia
- Volunteers
- 43 people
- Sponsor
- Universitas Indonesia
ART Adherence
Randomized Trial to Optimize Virologic Suppression Rates Using a Point-of-Care Urine Monitoring Assay (ROVING PUMA)
Antiretroviral therapy (ART) has significantly decreased the morbidity and mortality of HIV infection. However, adherence challenges in taking daily oral ART persist.
- Trial name
- ROVING-PUMA (NCT06423612)
- Testing
- POC urine assay informed enhanced ART adherence counselling for viral suppression
- Where
- South Africa
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Wheezing
PREcision Medicine Directed Corticosteroids In Children With preSchool Wheeze
Young children frequently attend the emergency department (ED) with wheeze which is usually triggered by a virus infection, such as the common cold.
- Trial name
- PRECISE (NCT06580600)
- Testing
- Point of care respiratory virus testing
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Acute Gastrointestinal Bleeding
Point-of-care Ultrasound Interest in Acute Gastrointestinal Bleeding Emergency Department Patients
Acute Gastrointestinal (GI) Bleeding are a common chief complaint among Emergency Department. The mortality rate for Lower GI Bleeding is 3.9%. While the mortality rate can be as high as 10% for Upper GI Bleeding.
- Trial name
- NCT04436575
- Testing
- Point-of-care ultrasound
- Where
- France
- Volunteers
- 150 people
- Sponsor
- SUD Association pour le Développement de la Recherche et de lEnseignement
Sepsis
Procalcitonin in Diagnosis of Bacterial Infections in Young Infants
A diagnostic accuracy study investigating the accuracy of procalcitonin in diagnosing invasive bacterial infections in your infants.
- Trial name
- NCT03509727
- Where
- United Kingdom
- Volunteers
- 126 people
- Sponsor
- Belfast Health and Social Care Trust
Diaphragm Dysfunction
Point of Care Ultrasound to Evaluate Diaphragmatic Function in Children Undergoing Thoracic Surgery
In children undergoing pulmonary resection, the diaphragm function is evaluated using ultrasound before and after surgery to evaluate the incidence of diaphragm dysfunction after pulmonary resection.
- Trial name
- NCT04400370
- Testing
- Diaphragm ultrasound
- Where
- South Korea
- Volunteers
- 75 people
- Sponsor
- Seoul National University Hospital
Diabetes Mellitus, Type 2, Cardiovascular Diseases
Integrating Abbott Point-of-Care Technologies and the Community Scientist Model to Support HbA1c Testing Per ADA
In the United States, the growing Hispanic/Latino population is at high risk for type 2 diabetes and associated complications, yet underserved in healthcare and underrepresented in research.
- Trial name
- NCT05000840
- Testing
- Enrollment in existing SDRI diabetes education programs
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- Sansum Diabetes Research Institute
Acute Coronary Syndrome
Pre-hospital Rule-out of Acute Coronary Syndrome
Patients with chest pain suspected for non ST-segment elevation acute coronary syndrome (NSTE-ACS) are routinely transferred to the emergency department (ED).
- Trial name
- ARTICA (NCT05466591)
- Testing
- Pre-hospital rule-out strategy
- Where
- Netherlands
- Volunteers
- 866 people
- Sponsor
- Radboud University Medical Center
Pediatric Respiratory Diseases, Respiratory Failure
Use of Lung Ultrasound to Diagnose the Etiology of Respiratory Failure in a PICU.
The purpose of this study is to determine the utility of point-of-care lung ultrasound (POC-LUS) in identifying the etiology of acute respiratory failure in pediatric patients admitted to the pediatric intensive care unit.
- Trial name
- NCT03744169
- Testing
- Lung ultrasound, Clinical exam, Chest x-ray
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of Wisconsin, Madison
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