Clinical trials: Placebo
Turmeric, Placebo
Effects of 8 Weeks of Turmeric Ingestion on Physiology and Wellbeing in Healthy Older Adults
Curcumin (a bioactive compound found in turmeric) has demonstrated anti-inflammatory and antioxidant properties, and there is evidence to suggest that it may produce improvements in quality of life and markers of health in humans…
- Trial name
- NCT07196514
- Testing
- Raw turmeric shots
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Nottingham Trent University
Placebo Analgesia, Pediatric Pain
Applying a Small Procedure Prior to Injection/Vaccination Reduces Pain in Children
In this proposed study, the investigators aim to apply a minor procedure prior to a treatment that induces pain (e.g., injection/vaccination) to help manage pediatric pain.
- Conditions
- Placebo Analgesia, Pediatric Pain, Vaccination
- Trial name
- NCT06313788
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Lingnan University
Placebo Effect, Mindfulness
Interactions Between Placebo Effects and Mindful Awareness State
In this experiment,the investigators study the effects of interpersonally induced placebo effects and a mindful awareness induction on negative affect.
- Conditions
- Placebo Effect, Mindfulness, Pain, Transcranial Direct Current Stimulation (tDCS)
- Trial name
- NCT07108101
- Testing
- tDCS stimulation (real), Mindful state induction, No minfulness induction
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
Testosterone, Placebos
A Multinomial Process Model of Moral Judgment
The main goal of this project to investigate the psychological processes underlying moral judgments in social dilemmas. We will examine neuroendocrine determinants of moral judgment by investigating the effects of exogenous…
- Trial name
- PSY (NCT02799277)
- Testing
- Testosterone
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- Robert Josephs
Nitrate, Placebo - Control
Beetroot Juice and Neuromuscular Performance in Female Basketball Players
A randomized, double-blind, placebo-controlled study investigates the effects of 5 days of nitrate-rich beetroot juice supplementation (70 mL·day-¹; 6.4 mmol NO₃-·day-¹) on physical performance in female basketball players.
- Trial name
- BASKET_BEET (NCT07833579)
- Testing
- Beetroot juice supplementation
- Where
- Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidad Pontificia Comillas
Physical Performance, Placebo Effect
Placebo Effect on Cycling Performance: Laboratory Crossover Study
This study aims to determine the impact of the placebo (PLA) effect on physical and cognitive performance in a controlled laboratory setting.
- Conditions
- Physical Performance, Placebo Effect, Cognitive Performance
- Trial name
- NCT07748429
- Testing
- Caffeine (6mg/kg)
- Where
- Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Lymphedema, Lower Limb, Extracorporeal Shock Wave Therapy
Extracorporeal Shock Wave Therapy in Lower Extremity Lymphedema
Lower extremity lymphedema is a chronic and progressive condition associated with significant functional impairment and reduced quality of life.
- Conditions
- Lymphedema, Lower Limb, Extracorporeal Shock Wave Therapy, Edema Leg, Sham-controlled
- Trial name
- NCT07626645
- Testing
- Extracorporeal Shock Wave Therapy (ESWT)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gazi University
Naltrexone, Placebo
Understanding How Opioids Affect the Experiential and Neural Signatures of Social Experiences
The study is a randomized, placebo-controlled design with the opioid antagonist, oral naltrexone. Following random assignment, participants will take 50mg of naltrexone or placebo once a day for 7 days.
- Trial name
- NCT05007561
- Testing
- Naltrexone Hydrochloride
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Beta Alanine Supplementation, Placebo - Control
Beta-Alanine Effects on Neuromuscular and Cardiovascular Performance in Female Rugby Players
This study will examine the effects of beta-alanine supplementation on physical performance in female rugby players, who will ingest 4.8 grams/day over a four-week period.
- Trial name
- BA_RUGBY (NCT07809321)
- Testing
- Beta-Alanine
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Pontificia Comillas
Intrathecal Morphine, Intrathecal Dexmedetomidine
Intrathecal Morphine Versus Intrathecal Dexmedetomidine Compared to Placebo for Postoperative Pain Relief After Spine Fixation Surgeries
This study aims to compare the efficacy of intrathecal morphine and intrathecal dexmedetomidine in reducing pain following lumbar spine fixation surgeries.
- Conditions
- Intrathecal Morphine, Intrathecal Dexmedetomidine, Placebo, Postoperative Pain
- Trial name
- NCT07777627
- Testing
- Intrathecal Morphine, Intrathecal Dexmedetomidine, Normal Saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Suvorexant, Placebo
Suvorexant as an Adjunct to Buprenorphine in Persons Who Use Fentanyl
This is a 4-week, randomized-controlled trial of suvorexant vs placebo in persons with opioid use disorder who have recent fentanyl exposure.
- Conditions
- Suvorexant, Placebo, Opioid Use Disorder
- Trial name
- NCT05145764
- Testing
- Suvorexant
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Johns Hopkins University
Physical Performance, Placebo Effect
Placebo Effect in Field-Based Physical Performance
This study aims to investigate the placebo (PLA) effect on physical performance across different sports disciplines in real-world, field-based settings.
- Conditions
- Physical Performance, Placebo Effect, Cognitive Performance
- Trial name
- NCT07742150
- Testing
- Caffeine (6mg/kg)
- Where
- Poland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Caffeine, Placebo - Control
Acute Caffeine Intake in Older Adults
Evidence regarding the ergogenic effects of caffeine is well-established in young adults, but evidence in older adults remains scarce, particularly during dynamic resistance exercise.
- Trial name
- CAF+OLD (NCT07711665)
- Testing
- Caffeine
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Caffeine, Placebo
Acute Caffeine Intake in Young vs Older Adults
Evidence regarding the ergogenic effects of caffeine is well-established in young adults, but evidence in older adults remains scarce, particularly during dynamic resistance exercise.
- Trial name
- CAF+Age (NCT07711652)
- Testing
- Caffeine
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Placebo - Control, Ketone Monoester
The Effects of Exogenous Ketones on Cognitive Function
The purpose of this study is to evaluate the acute effects of exogenous ketone monoester (KME) supplementation on cognitive function in three groups of adults aged 19-55 years: (1) obese, sedentary individuals; (2) lean…
- Trial name
- NCT07051655
- Testing
- Ketone Monoester (KE)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Pain, Virtual Reality
Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG)
This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia.
- Conditions
- Pain, Virtual Reality, Placebo, Temporomandibular Disorder
- Trial name
- VR TMD EEG (NCT06214923)
- Testing
- RelieVRx, No-VR (natural history control)
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- University of Maryland, Baltimore
Kidney Transplant Recipient, Sodium Glucose Co-Transporter 2 Inhibitors
SGLT2i Effect on PTDM Development and Kidney Allograft Function in Non-diabetic Kidney Transplant Recipients: A Randomized, Doubleblind, Placebo Controlled, National Multicenter Trial
The goal of this clinical trial is to find out whether 12 months of treatment with the SGLT2 inhibitor Forxiga® (dapagliflozin 10 mg once daily), compared with placebo, can reduce the risk of developing post-transplant diabetes…
- Conditions
- Kidney Transplant Recipient, Sodium Glucose Co-Transporter 2 Inhibitors, Non-Diabetic Patients, Randomized Controlled Trial (RCT)
- Trial name
- SGL-TX-PTDM (NCT07682350)
- Testing
- SGLT2i
- Where
- 3 sites in Denmark
- Volunteers
- 184 people
- Sponsor
- Odense University Hospital
Hip Fracture, Anemia
IRONCARE: Iron Treatment in Older Patients With Hip Fractures
The aim of this study is to investigate the effects of intravenous (IV) iron therapy compared to alternate-day oral iron treatment and no supplementation in older patients with hip fractures.
- Conditions
- Hip Fracture, Anemia, Iron, Placebo - Control
- Trial name
- NCT07659184
- Testing
- Ferric Derisomaltose, Oral Iron (Ferrous sulphate)
- Where
- 5 sites in Denmark
- Volunteers
- 528 people
- Sponsor
- University of Aarhus
Social Anxiety Disorder (SAD), Attention Bias Modification Treatment (ABMT)
Efficacy of Attention Bias Modification vs. Placebo for Social Anxiety Disorder
This study examines whether a computerized attention-training intervention called attention bias modification (ABM) can reduce symptoms of social anxiety disorder (SAD) in adults, and whether symptom improvement is specifically…
- Conditions
- Social Anxiety Disorder (SAD), Attention Bias Modification Treatment (ABMT), Placebo Effect
- Trial name
- NCT07666776
- Testing
- Dot-Probe Attention Bias Modification (ABM)
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Tel Aviv University
Negative Affectivity, Non-invasive Brain Stimulation
Neural Mechanisms of Interpersonal Expectations on Negative Affect
The goal of this clinical trial is to learn whether non-invasive brain stimulation, called transcranial temporal interference stimulation (tTIS), can reduce negative affect, and how expectations shaped by care providers influence…
- Conditions
- Negative Affectivity, Non-invasive Brain Stimulation, Placebo Effect, Expectations
- Trial name
- NCT06980090
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College