Clinical trials: Physical Function
Vaginal Birth After Cesarean
Vaginal Birth After Caesarean Section - Effect on Maternal Psychosocial Function
The incidence of caesarean section has reached 15-20% in most developed countries. Encouraging vaginal birth after caesareans section (VBAC) has been considered a key component of a strategy to reduce the caesarean section rate.
- Trial name
- NCT00294411
- Testing
- elective cesarean section
- Sponsor
- Chinese University of Hong Kong
Pacemaker DDD, Cardiopulmonary Endurance
Effect of Standardized Exercise on Cardiopulmonary Function in Patients With Permanent Pacemaker Implantation
The purpose of this study is to observe the changes of cardiopulmonary endurance in patients with pacemaker implantation after long-term exercise, to explore the significance of exercise on patients with pacemaker implantation…
- Trial name
- NCT04957771
- Testing
- Supervise and guide regular exercise
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Peking University Third Hospital
Advanced Malignancies, Tumors
A Study of Patupilone in Patients With Advanced Solid Tumors and Varying Degrees of Hepatic Function
Patients who participated in the core EPO2121 study and did not clinically progress may participate in this extension protocol to further evaluate the safety, tolerability, and efficacy of patupilone.
- Trial name
- NCT00421044
- Testing
- Patupilone/EPO906
- Where
- 3 sites in United States
- Volunteers
- 14 people
- Sponsor
- Novartis Pharmaceuticals
Postoperative Pulmonary Complications, Respiratory Insufficiency
The PROtective Ventilation Using Open Lung Approach Or Not Trial
Postoperative Pulmonary Complications (PPC) are very common. It severely affects postoperative recovery, particularly in the abdominal surgery.
- Trial name
- PROVOLON (NCT03160144)
- Testing
- open lung approach
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Lumbar Spinal Stenosis
Quantitative Evaluation of Motor Function Before and After Surgery for Degenerative Lumbar Spinal Stenosis
Low back pain is a leading cause of medical consultations in France and in other industrialized countries. Although spinal surgery is a recognized treatment, to date, its impact has only been assessed using subjective or…
- Trial name
- SPEED (NCT03194607)
- Testing
- Functional walk tests, 3D analysis of locomotion and posture, questionnaires
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Metabolic Syndrome, Endothelial Dysfunction
Effect of Eplerenone on Endothelial Function in Metabolic Syndrome
Patients with the metabolic syndrome (MetSyn) are at increased risk for cardiovascular mortality and morbidity.This increased cardiovascular risk is attributed to metabolic dysregulations like impaired glucose tolerance or…
- Trial name
- MetSyn (NCT01319344)
- Testing
- Eplerenone
- Where
- 2 sites in Germany
- Volunteers
- 42 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Oral Health
A Study on the Correlation Between Oral Health and Delirium in Surgical Inpatients
Delirium is a clinical syndrome characterized by acute attention deficits, altered consciousness, and fluctuating cognitive dysfunction, typically triggered by multifactorial causes such as physical illness, medication use, or…
- Trial name
- NCT06969092
- Testing
- Oral Frailty
- Where
- China
- Volunteers
- 550 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Polycystic Ovary Syndrome, Urine Albumin \(UAlb\)
Urine Albumin/Creatinine Ratio and Renal Function Differences in Phenotypes of Polycystic Ovary Syndrome.
Since there are different metabolic effects in different phenotypes of polycystic ovary syndrome (PCOS); in this study; the investigators aimed to investigate whether there is a difference between glomerular filtration rate…
- Conditions
- Polycystic Ovary Syndrome, Urine Albumin \(UAlb\), Urine Creatinine \(UCr\), Glomerular Filtration Rate
- Trial name
- NCT07441811
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Uşak University
Neurodegenerative Diseases, Frontotemporal Degeneration
Clearance Mechanisms in Atypical Neurodegenerative Diseases
The project PeptiClear aims to investigate whether the blood-brain-barrier (BBB) and the glymphatic system are compromised in atypical neurodegenerative diseases, and whether Alzheimer´s disease (AD)-related copathology, vascular…
- Trial name
- PeptiClear (NCT05317871)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Dilated Cardiomyopathy
Bone Marrow Derived Adult Stem Cells for Dilated Cardiomyopathy
A randomised, double-blind, placebo-controlled trial to evaluate the role of intracoronary injection of progenitor cells compared to placebo injection in patients with Dilated Cardiomyopathy who have been pre-treated with G-CSF…
- Trial name
- REGEN-DCM (NCT01302171)
- Testing
- granulocyte colony stimulating factor (GCSF), bone marrow mononuclear cells
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Barts & The London NHS Trust
Chronic Obstructive Pulmonary Disease
Quality of Life in Daxas-treated Patients Older Than 18 Years With Severe Chronic Obstructive Pulmonary Disease (COPD) (DACOTA)
Chronic obstructive pulmonary disease (COPD) is a progressive and largely irreversible lung disease characterized by chronic bronchitis and/or emphysema, resulting in breathlessness, cough and sputum.
- Trial name
- DACOTA (NCT01285167)
- Testing
- Daxas
- Where
- 605 sites in Germany
- Volunteers
- 3,645 people
- Sponsor
- AstraZeneca
Knee Osteoarthritis
Effect of Antigravity Treadmill in Knee Osteoarthritis (AGTreadmill)
To date, the anti-gravity treadmill, as a representative method of lower body positive pressure treadmills, has been rarely reported for knee osteoarthritis rehabilitation.
- Trial name
- AGTreadmill (NCT06347692)
- Testing
- antigravity treadmill, physical therapy exercise program
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Prince Sattam Bin Abdulaziz University
Cirrhosis
Propofol Versus Midazolam for Upper Endoscopy in Cirrhotic Patients
Upper GI endoscopy is often performed in patients with chronic liver disease to screen for esophageal and gastric varices. The purpose of this study is to compare propofol to midazolam for sedation in patients with chronic liver…
- Trial name
- NCT01141036
- Testing
- propofol, Midazolam
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Ziv Hospital
Football Players
Effects of Windlass Versus Calcaneal Taping in Football Player With Plantar Fasciitis.
Plantar fasciitis is a prevalent ailment that affects the plantar fascia, a dense tissue strip that spans the underside of the foot, from the heel bone to the toes.
- Trial name
- NCT06637592
- Testing
- Calcaneal taping, Windlass taping
- Where
- 2 sites in Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Chalazion
Efficacy of Intense Pulsed Light in the Treatment of Recurrent Chalazia
The purpose of the present study was to investigate the efficacy of intense pulse light and meibomian glands expression in cases of recurrent chalazion after surgery.
- Trial name
- NCT05070611
- Testing
- IPL-MGX
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Coronary Disease, Myocardial Infarction
Stem Cell Therapy to Improve Myocardial Function in Patients Undergoing Coronary Artery Bypass Grafting (CABG)
The purpose of this study is to determine whether intracoronary transfer of autologous bone marrow cells can induce angiogenesis, subsequently improving regional myocardial perfusion, and finally resulting in improved systolic…
- Trial name
- NCT00395811
- Testing
- Bone Marrow Stem Cell Therapy combined CABG
- Where
- China
- Volunteers
- 50 people
- Sponsor
- China National Center for Cardiovascular Diseases
Cerebral Palsy (CP)
Effect of a Humanoid Robot With Virtual Reality Games to Train Arm Function in Children With Cerebral Palsy - THRIVE Trial
About 60% of children with cerebral palsy (CP) have impaired arm function. Improving arm function requires hundreds of repetitions per day, which is impossible in a single clinical visit.
- Trial name
- THRIVE (NCT06881407)
- Testing
- Robot, Virtual Reality
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Georgia State University
Reproductive Performance Following Ovarian Transplantation
Transplantation of Frozen Thawed Ovarian Tissue High Reproductive Performance
Design: prospective cohort study. Setting: Tertiary university-affiliated ART and oncology centers. Patients: 20 cancer survivors who underwent ovarian transplantation of frozen-thawed ovarian tissue, with the aim to conceive.
- Trial name
- NCT02659592
- Testing
- transplantation of ovarian tissue
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Intercostal Nerve Block, Pulmonary Ventilation
EIT Evaluation of Pulmonary Ventilation With Different Ropivacaine Concentrations in Intercostal Nerve Blockade
This study aims to find out how different strengths of the anesthetic drug ropivacaine affect lung breathing function when used in intercostal nerve block (a type of local anesthesia) for breast quadrantectomy surgery.
- Conditions
- Intercostal Nerve Block, Pulmonary Ventilation, Anesthesia, Local, Breast Neoplasms
- Trial name
- EIT (NCT07079436)
- Testing
- 0.25% ropivacaine, 0.375% Ropivacaine, 0.5% Ropivacaine
- Where
- China
- Volunteers
- 67 people
- Sponsor
- Fudan University
Cognitive Function
Cognition Intervention Study Dortmund- Glycemic Index (CogniDo GI)
The Cognition Intervention Study Dortmund (CogniDo) and the Cognition Intervention Study Dortmund PLUS (CogniDo PLUS) investigated the short-term effects of having school lunch versus skipping it on children's basal (CogniDo) and…
- Trial name
- CogniDo-GI (NCT02763371)
- Testing
- Dietary: high GI lunch, Dietary: low GI lunch
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Research Institute of Child Nutrition, Dortmund
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