Clinical trials: Phantom Pain
Phantom Limb Pain
Mixed Reality Based System to Manage Phantom Pain Phantom Pain for Patients With Lower Limb Amputation
The primary goals of this pilot research project are a) to design and develop the a mixed reality based system for managing phantom pain and b) to evaluate the feasibility and preliminary functional outcomes of this system in a…
- Trial name
- MrMAPP (NCT04529083)
- Testing
- Mr. MAPP
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Dallas VA Medical Center
Neuropathic Pain, Phantom Limb Pain
Clinical Evaluation of the Medical Device (MD) (Caloprothese Connected Kit, CCK)
Neuropathic pain is common in limb amputees and causes reductions in activity and participation as well as impaired quality of life.
- Trial name
- KCC (NCT04748484)
- Testing
- KCC Active or inactive
- Where
- 4 sites in France
- Volunteers
- 12 people
- Sponsor
- Gregand Innovations
Phantom Limb Pain
Comparison of Efficacy of Mirror Therapy vs Mental Imagery in Reduction of Phantom Limb Pain in AKAP
Limb amputation results in many types of pain, including localized pain at the stump and projected pain experienced by the patient in the location where the amputated limb used to be, known as phantom limb pain (PLP).
- Trial name
- NCT06428123
- Testing
- Mirror Therapy on present Lower Limb, Mental Imagery on present Lower Limb
- Where
- 2 sites in Pakistan
- Volunteers
- 24 people
- Sponsor
- Superior University
Phantom Limb Pain
Virtual Mirror Therapy for Relief of Chronic Phantom Limb Pain
The purpose of this project is to further investigate the use of Virtual Mirror therapy for alleviating symptoms of chronic phantom limb pain.
- Trial name
- NCT05194800
- Testing
- Virtual Mirror Therapy
- Sponsor
- University of Alabama at Birmingham
Phantom Limb Pain
Treating Phantom Limb Pain Using Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study
When a limb is traumatically severed, pain perceived in the part of the body that no longer exists often develops. This is called "phantom limb" pain, and is different from "stump" pain, which is pain within the part of the limb…
- Trial name
- DoD-PLP-Tx (NCT01824082)
- Testing
- Perineural infusion [continuous peripheral nerve block(s)]
- Where
- 4 sites in United States
- Volunteers
- 144 people
- Sponsor
- University of California, San Diego
Phantom Pain Following Amputation of Lower Limb
the Influence of Virtual Reality Approach on Phantom Pain in Trans Tibial Amputation
1. To investigate the effect of Virtual reality (VR) on phantom limb pain in trans tibial amputation. 2. To investigate the effect of Virtual reality (VR) on lower limb Function in trans tibial amputation.
- Trial name
- NCT06262503
- Testing
- Virtual Reality, Transcutaneous Electrical Nerve Stimulation (TENS), Mirroring Therapy
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Cairo University
Targeted Sensory Reinervation, Amputation
Targeted Sensory Reinnervation (TSR) in Hand Amputation
If a person has to have a part of their body amputated, in this case their hand, the patient then lacks information about the missing limb, which in many cases leads to pain that severely restricts their quality of life and…
- Conditions
- Targeted Sensory Reinervation, Amputation, Phantom Pain
- Trial name
- NCT06249594
- Testing
- targeted sensory reinervation
- Where
- 2 sites in Austria, Italy
- Volunteers
- 3 people
- Sponsor
- Brixsana Private Clinic - Centro di Chirurgia Plastica, Estetica ed Ricostruttiva con Chirurgia dell
Phantom Limb Pain
Graded Motor Imagery in Phantom Limb Pain (GraMI Protocol)
The International Association for the Study of Pain defines phantom limb pain (PLP) as that pain referred to a part of the body that has been previously removed as if it were still present.
- Trial name
- GraMI (NCT05083611)
- Testing
- GraMI
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- University of Vic - Central University of Catalonia
Phantom Limb Pain
The Effect of Distant Reiki on Pain and Holistic Well-being
Phantom limb pain is a condition characterized by painful sensations in the missing part of the amputated limb, which reduces the quality of life of the individual.
- Trial name
- NCT05684445
- Testing
- Distant reiki group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Aksaray University Training and Research Hospital
Pain, Pain Syndrome
Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis
Over the last years a rising medical need for treatment of chronic pain was identified. Based on previous findings indicating the pain modulating effects of cannabinoids in chronic pain disorders, this clinical trial investigates…
- Conditions
- Pain, Pain Syndrome, Pain, Chronic, Chronic Pain
- Trial name
- NCT06071949
- Testing
- Adezunap
- Where
- Germany
- Volunteers
- 558 people
- Sponsor
- Apurano Pharmaceuticals GmbH
Pain, Pain Syndrome
Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis
Over the last years a rising medical need for treatment of chronic pain was identified. Based on previous findings indicating the pain modulating effects of cannabinoids in chronic pain disorders, this clinical trial investigates…
- Conditions
- Pain, Pain Syndrome, Pain, Chronic, Chronic Pain
- Trial name
- NCT06072001
- Testing
- Adezunap (AP707)
- Where
- Germany
- Volunteers
- 558 people
- Sponsor
- Apurano Pharmaceuticals GmbH
Phantom Limb Pain
Electrical Stimulus Therapy for Chronic Phantom Limb Pain
The goal of this pilot study is to assess the effectiveness of an electrical stimulation therapy option for the treatment of chronic phantom limb pain in upper or lower limb amputees.
- Trial name
- NCT03030079
- Testing
- Experimental Electrical Stimulation Regimen
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Amputation, Neuroma Amputation
Effect of Prophylactic TMR and RPNI on Neuroma and Phantom Limb Pain
The purpose of this study is to analyze the efficacy of novel interventions in post-amputation surgical care (specifically Targeted Muscle Reinnervation and Regenerative Peripheral Nerve Interface) on post-amputation pain and…
- Conditions
- Amputation, Neuroma Amputation, Phantom Limb Pain, Residual Limbs
- Trial name
- NCT05344261
- Testing
- Targeted Muscle Re-innervation, Regenerative Peripheral Nerve Interface, Standard Post-Amputation Surgical Care
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Neuropathic Pain, Phantom Limb Pain
Mechanisms and Treatment of Post-amputation Neuropathic Pain
Phantom and residual limb pain are types of peripheral neuropathic pain that are difficult to treat and where the underlying mechanisms are still not fully understood.
- Conditions
- Neuropathic Pain, Phantom Limb Pain, Amputation
- Trial name
- NCT04819503
- Testing
- Spinal anaesthesia (sub-study 1), Repetitive transcranial magnetic stimulation (sub-study 2)
- Where
- Norway
- Volunteers
- 1 people
- Sponsor
- Oslo University Hospital
Complex Regional Pain Syndromes, Postherpetic Neuralgia
The Comparison of Sympathetic Blockade of Stellate Ganglion Block and Thoracic Paravertebral Block
The purpose of this study is to investigate the effect of ultrasound-guided thoracic paravertebral block (TPVB) when performing sympathetic block for upper limb pain control.
- Conditions
- Complex Regional Pain Syndromes, Postherpetic Neuralgia, Phantom Limb Pain, Chronic Post Surgical Pain
- Trial name
- NCT04876989
- Testing
- US-SGB, US-TPVB
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Seoul National University
Amputation, Phantom Limb Pain
The Pain in Amputees Reduced by Administration of Diet Examination
Phantom limb pain (PLP) is defined as pain or discomfort in a missing limb following amputation, whereas residual limb pain (RLP) is often experienced as pain at the site of amputation.
- Conditions
- Amputation, Phantom Limb Pain, Residual Limb Pain
- Trial name
- PARADE (NCT05460845)
- Testing
- Low-Carbohydrate Diet
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Amputation, Phantom Limb Pain
Neuromodulation in Lower Limb Amputees
The goal of this study is to investigate the role of transcutaneous spinal cord stimulation on spinal cord excitability in lower limb amputees.
- Conditions
- Amputation, Phantom Limb Pain, Hoffman's Reflex
- Trial name
- NCT04543786
- Testing
- Transcutaneous spinal cord stimulation
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- University of Pittsburgh
Phantom Limb Pain
Phantom Motor Execution Via MPR, VR/AR, and SG, as a Treatment of PLP
This international, multi-center, double-blind, randomized, controlled clinical trial aims to evaluate the efficacy of Phantom Motor Execution (PME) and Phantom Motor Imagery (PMI) as treatments of Phantom Limb Pain (PLP).
- Trial name
- NCT03112928
- Testing
- Phantom Motor Execution, Phantom Motor Imagery
- Where
- 9 sites in United States, Canada and 5 more
- Volunteers
- 77 people
- Sponsor
- Integrum
Phantom Limb Pain, Phantom Pain
Study of Lower-limb Phantom Pain Syndrome Using Peripheral Nerve and Spinal Cord Stimulation
Brief Summary: The purpose of this study is to evaluate the effectiveness of neuromodulation for relief of phantom limb pain (PLP) using peripheral nerve (PNS) and spinal cord (SCS) stimulation with implantable electrodes.
- Conditions
- Phantom Limb Pain, Phantom Pain, Amputation, Lower Limb Amputation
- Trial name
- NCT05807607
- Testing
- Implantation of PNS electrodes during surgery, mapping to select sites with the best effect and daily modulation., SCS electrode implantation at surgery, mapping to select sites with the best effect and pain modulation, Change according to the scale of the PainDetect questionnaire
- Where
- Russia
- Volunteers
- 10 people
- Sponsor
- Artur Biktimirov
Post-Amputation Phantom Limb Pain
Cryoanalgesia to Treat Post-Amputation Phantom Limb Pain: A Department of Defense Funded Multicenter Study
When a limb is severed, pain perceived in the part of the body that no longer exists often develops and is called "phantom limb" pain.
- Trial name
- NCT03449667
- Testing
- Cryoneurolysis
- Where
- 6 sites in United States
- Volunteers
- 144 people
- Sponsor
- University of California, San Diego