Clinical trials: Peri-menopausal Women
Dyslipidemias, Obesity
Time-restricted Eating in Peri- and Postmenopausal Women
The overall objective of the study is to examine the effect of an 8-hour time-restricted eating intervention on lipid levels and body composition in peri- and recently postmenopausal women with untreated dyslipidemia.
- Conditions
- Dyslipidemias, Obesity, Menopause
- Trial name
- NCT06188598
- Testing
- Time-restricted eating
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Perimenopause, Perimenopausal Women
12-week Magnesium Supplementation on Peri-menopause Symptoms, Cognition, Sleep, and Psychological Well-being
Perimenopause is a transition phase into menopause, characterised by menopausal symptoms while menstrual periods are still occurring.
- Conditions
- Perimenopause, Perimenopausal Women, Perimenopause, Climacteric Syndrome
- Trial name
- NCT07235878
- Testing
- Magnesium hydroxide 375mg
- Where
- United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Menopause, Urinary Incontinence, Stress
Pelvic Floor Muscle Training With and Without Biofeedback in Women With Stress Urinary Incontinence
This study evaluates the action of the pelvic floor muscle training with and without EMG Biofeddback in the treatment of stress urinary incontinence in menopausal, peri and post menopausal women and their quality of life before…
- Trial name
- NCT02275728
- Testing
- Pelvic floor muscle training, Eletromyography Biofeedback
- Volunteers
- 45 people
- Sponsor
- Federal University of Rio Grande do Sul
Glucose Monitoring, Continuous, Whole Body Protein Metabolism
Effects of Amylopectin Chromium Blend on Whole-Body Protein Kinetics and Glucose in Peri/Post-Menopausal Women
The goal of this study is to better understand how an amylopectin chromium blend may influence whole body protein balance in women during midlife, when hormonal changes can adversely affect protein metabolism and muscle…
- Conditions
- Glucose Monitoring, Continuous, Whole Body Protein Metabolism, Peri-menopausal Women, Post-menopause
- Trial name
- NCT07402382
- Testing
- Amylopectin-chromium blend, Concentrated Amylopectin-chromium blend
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nutrition 21, Inc.
Vasomotor Symptoms, Menopause
FP-101 Versus Placebo in the Treatment of Menopausal Vasomotor Symptoms
This Phase II proof of concept study is designed to assess the safety and efficacy of FP-101 (60mg b.i.d.), an extended-release oral tablet product, compared to a matching placebo in the treatment of moderate-to-severe hot…
- Trial name
- NCT05312567
- Testing
- FP-101
- Where
- 12 sites in United States
- Volunteers
- 105 people
- Sponsor
- Fervent Pharmaceuticals
Depression, Depressive Disorder
Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) Versus Placebo in Peri- and Postmenopausal Women
Desvenlafaxine succinate (DVS) is a potent and selective serotonin and norepinephrine reuptake inhibitor (SNRI). The sustained-release (SR) formulation, DVS SR, is being studied in the development program for the treatment of…
- Conditions
- Depression, Depressive Disorder, Depressive Disorder, Major
- Trial name
- NCT00369343
- Testing
- Desvenlafaxine administered as a succinate salt in a sustained-release form (DVS SR)
- Where
- 37 sites in United States
- Volunteers
- 381 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Menopausal Symptoms
A Clinical Trial on the Efficacy of a Combination Herbal Product, Biotropics' Nu Femme, on Menopausal Symptoms and Quality of Life in Women
The purpose of this study is to assess the effectiveness of an herbal combination product called Nu Femme, on menopausal symptoms in peri-menopausal women.
- Trial name
- 14NMHB (NCT02269891)
- Testing
- Nu Femme
- Where
- 4 sites in Canada
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- KGK Science Inc.
Osteoporosis, Osteopenia
Melatonin Osteoporosis Prevention Study
Osteoporosis is one of the most common skeletal disorders. Today in the United States, 10 million individuals have osteoporosis and 34 million more have low bone mass or osteopenia, which places them at an increased risk of some…
- Trial name
- MOPS (NCT01152580)
- Testing
- melatonin, sugar pill
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Duquesne University
Nonalcoholic Steatohepatitis, Liver Fibroses
Liver Fibrosis in Peri-menopausal Women
This is a prospective observational study in a single medical center. The aim is to evaluate the status of fibrosis and steatosis of liver parenchyma in peri-menopausal women using noninvasive methods of vibration-controlled…
- Conditions
- Nonalcoholic Steatohepatitis, Liver Fibroses, Menopause
- Trial name
- NCT03602573
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Chang Gung Memorial Hospital
Menopause
Menopausal Symptoms Probiotic Study
In this study, we want to investigate if the active product consisting of a probiotic blend can potentiate the recirculation of active oestrogens into the bloodstream and help to mitigate menopause symptoms, which are closely…
- Trial name
- NCT06446869
- Testing
- Gyntima Menopause
- Where
- United Kingdom
- Volunteers
- 140 people
- Sponsor
- Community Pharmacology Services Ltd
Breast Cancer
Weight Loss Plus Omega-3 Fatty Acids or Placebo in High Risk Women
The purpose of this study is to determine if high dose supplementation with the omega-3 fatty acids EPA and DHA, when added to a weight loss program, is well tolerated in the study population and if there is an increase in the…
- Trial name
- NCT02101970
- Testing
- Omega-3 Fatty Acids, Diet and Exercise
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Carol Fabian, MD
Pregnancy
Urine Sample Collection From Non Pregnant Peri and Post-menopausal Women
This is a sample collection study, participants will be required to collect one (if last menstrual period ≥12 months) or two (if last menstrual period <12 months) urine samples and return them to the study site, together with…
- Trial name
- NCT02945189
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- SPD Development Company Limited
Dry Eye
Herbal Medication to Treat Dry Eye in Peri/ Post-menopausal Women
Dry eye disease (DED) in less severe forms are very common, and should ideally be treated outside hospitals, eg., through primary care services and exploiting holistic therapies such as traditional medicine.
- Trial name
- NCT05319041
- Testing
- Wei's Qi Ju Gan Lu Formula
- Where
- Singapore
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Breast Cancer
Pilot Study of the Effect of Duavee® on Benign Breast Tissue Proliferation
The purpose of this study is to learn whether daily use of Duavee® is accepted and tolerated by peri- and post-menopausal women at moderate risk for development of breast cancer.
- Trial name
- NCT02729701
- Testing
- Duavee
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- University of Kansas Medical Center
Menopause
A Survey Evaluating Prevalence, Severity and Associated Factors in East Asian Women With Moderate-to-severe Menopause-related Vasomotor Symptoms (MR-VMS)
The purpose of this study is to estimate the prevalence of Vasomotor Symptoms (VMS) and prevalence of moderate to severe VMS in peri-menopausal women and post-menopausal women aged 40-65 in East Asia (China, South Korea and…
- Trial name
- NCT04553029
- Testing
- No intervention
- Where
- 3 sites in China, South Korea and 1 more
- Volunteers
- 3,399 people
- Sponsor
- Astellas Pharma Singapore Pte. Ltd.
Menopause, Premature, Menopause Related Conditions
Autologous PRP Infusion May Restore Ovarian Function and May Promote Folliculogenesis in POI Patients
Autologous PRP intra ovarian infusion may restore ovarian function, may promote folliculogenesis and may improve patients' hormonal profile in patients presenting with POI.
- Conditions
- Menopause, Premature, Menopause Related Conditions, Menopausal Syndrome, Premature Ovarian Failure
- Trial name
- PRP (NCT04031456)
- Testing
- Autologous Platelet Rich Plasma
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Genesis Athens Clinic
Perimenopause, Perimenopausal Women
12-week Multi-vitamin/Mineral Supplementation on Peri-menopause Symptoms, Cognition, Sleep, and Psychological Well-being.
Perimenopause is a stage of transition into menopause that is marked by menopausal symptoms while menstruation is still taking place.
- Conditions
- Perimenopause, Perimenopausal Women, Perimenopause, Climacteric Syndrome
- Trial name
- NCT07242430
- Testing
- Multivitamin/mineral supplement
- Where
- United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Menopause, Perimenopause
Cuidar-ME, a Web-based Psychological Intervention for (Peri)Menopausal Women: A Pilot Randomized Controlled Trial
The Cuidar-ME program is a web-based cognitive-behavioral intervention designed to promote well-being and mental health in women during (peri)menopause.
- Trial name
- Cuidar-ME (NCT07672002)
- Testing
- Cuidar-ME
- Where
- Portugal
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Menopause
DBPCT Effects of Omega-3 FA on Memory and Cognition in Peri- and Menopausal Women
The goal of this clinical trial is to learn if daily omega-3 supplementation improves memory and cognitive function in perimenopausal and menopausal women aged 40-60 years.
- Trial name
- NCT07814300
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Dyslipidemia, Menopause
Dose-response Study of Carduus Marianus in Centesimal Scale for Dyslipidemia in Climacteric Overweighed or Obese Women.
Metabolic disorders including hypercholesterolemia and hypertriglyceridemia are present in climacteric women. Carduus marianus is a homeopathic medicine that traditionally has been used for hepatic diseases.
- Conditions
- Dyslipidemia, Menopause, Obesity
- Trial name
- NCT02775448
- Testing
- Carduus marianus 6cH, Carduus marianus 12cH, Carduus marianus 30cH
- Where
- Mexico
- Volunteers
- 62 people
- Sponsor
- Hospital Nacional Homeopático, Mexico