Clinical trials: Pentosan Polysulfate
Chronic Interstitial Cystitis
Pentosan Polysulfate Treatment's Effectiveness
To examine the relationship between symptoms and quality of life before and after oral pentosan polysulfate (PPS) treatment in cases diagnosed with interstitial cystitis/painful bladder syndrome (IC/BPS).
- Trial name
- NCT05744908
- Testing
- Pentosan Polysulphate
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Hisar Intercontinental Hospital
Osteoarthritis, Knee
Treatment Effects of Subcutaneous Injections of Pentosan Polysulfate Sodium vs Placebo in Participants With Knee OA Pain
The purpose of this study is to measure the change in pain and function with subcutaneous injections of pentosan polysulfate sodium (PPS) compared with subcutaneous injections of placebo in participants with knee osteoarthritis…
- Trial name
- NCT04809376
- Testing
- Pentosan Polysulfate Sodium twice weekly, Pentosan Polysulfate Sodium Fixed Dose, Pentosan Polysulfate Sodium once weekly
- Where
- 33 sites in United States, Australia
- Volunteers
- 602 people
- Sponsor
- Paradigm Biopharmaceuticals USA (INC)
Prostatitis
An Effectiveness and Safety Study of ELMIRON (Pentosan Polysulfate Sodium) for the Treatment of Chronic Non-Bacterial Inflammation of the Prostate Gland
The purpose of this study is to evaluate the safety and effectiveness of ELMIRON® in the treatment of chronic non-bacterial inflammation of the prostate gland.
- Trial name
- NCT00236990
- Testing
- pentosan polysulfate sodium
- Volunteers
- 283 people
- Sponsor
- McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.
Radiation Cystitis
Radiation Cystitis Treated With Pentosan Polysulfate Sodium Trial
The purpose of this study is to evaluate the efficacy and safety of pentosan polysulfate sodium versus placebo and in patients with radiation cystitis who have received radiation therapy in pelvic region.
- Trial name
- NCT05245591
- Testing
- Pentosan Polysulfate Sodium 100 MG Oral Capsule
- Where
- Taiwan
- Volunteers
- 72 people
- Sponsor
- National Taiwan University Hospital
Lower Urinary Tract Symptoms, Bladder Carcinoma
Prevention and Management of Intravesical BCG-related Lower Urinary Tract Symptoms
Common local side effects are generally seen during induction and during the first 6 months of BCG maintenance. BCG-related cystitis is frequent and unavoidable.
- Conditions
- Lower Urinary Tract Symptoms, Bladder Carcinoma, BCG
- Trial name
- NCT03549650
- Testing
- Pentosan Polysulfate Na 100Mg Cap
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Bladder Pain Syndrome, Pentosan Polysulfate
Efficacy Study of Pentosan Polysulfate Sodium,Hydrodistension and Combination Therapy for Bladder Pain Syndrome
The efficacy of pentosan polysulfate sodium, hydrodistension and combination therapy in patients with bladder pain syndrome.
- Conditions
- Bladder Pain Syndrome, Pentosan Polysulfate, Hydrodistension
- Trial name
- NCT01895153
- Where
- South Korea
- Volunteers
- 91 people
- Sponsor
- Samsung Medical Center
Pigmentary Maculopathy, Pigmentary Retinopathy
A Study of Pentosan Polysulfate Sodium and the Development of Pigmentary Maculopathy and Pigmentary Retinopathy
The purpose of this study is to evaluate incidence and prevalence rates of the study endpoints (pigmentary maculopathy [PM]/ pigmentary retinopathy [PR]/Any, PM/PR/ pentosan polysulfate sodium [PPS], and PM/PR/Non-PPS) in…
- Conditions
- Pigmentary Maculopathy, Pigmentary Retinopathy, Interstitial Cystitis
- Trial name
- NCT05179460
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Janssen Research & Development, LLC
Osteoarthritis, Knee
Treatment and Duration Effect of Pentosan Polysulfate Sodium (PPS) in Participants With Knee Osteoarthritis Pain
The purpose of this study is to measure the duration of treatment effect with subcutaneous injections of pentosan polysulfate sodium (PPS) compared with placebo in adult participants with knee osteoarthritis (OA) pain.
- Trial name
- NCT04814719
- Testing
- Pentosan Polysulphate Sodium
- Where
- 2 sites in United States, Australia
- Volunteers
- 133 people
- Sponsor
- Paradigm Biopharmaceuticals Ltd.
Recurrent Urinary Tract Infections in Women
Evaluate the Efficacy and Safety of U101 Oral Capsules in the Prevention of Uncomplicated rUTIs in Women
The goal of this clinical trial is to learn if drug U101 works to prevent recurrent urinary tract infection (rUTI) in women (≥ 20 and < 76 years old) with a medical history.
- Trial name
- U101 (NCT07184827)
- Testing
- U101
- Where
- 18 sites in Taiwan
- Volunteers
- 348 people
- Sponsor
- TCM Biotech International Corp.
Psychotic Disorders, Schizophrenia
Pentosan Polysulfate Sodium and Meclofenamic Acid as Treatments in Patients With Psychotic Disorders
This study evaluates the feasibility of administering meclofenamic acid or pentosan polysulfate sodium as an adjunctive treatment to patients diagnosed with a psychotic disorder.
- Conditions
- Psychotic Disorders, Schizophrenia, Schizoaffective Disorder, Bipolar Disorder
- Trial name
- NCT02930005
- Testing
- Meclofenamic acid, Pentosan polysulfate sodium
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- The University of Texas Health Science Center, Houston
Diarrhea, Radiation Enteritis
Pentosan Polysulfate in Treating Patients With Gastrointestinal Disturbance Caused by Radiation Therapy
RATIONALE: Pentosan polysulfate may be effective in treating side effects of radiation therapy to the abdomen or pelvis. It is not yet known whether pentosan polysulfate is more effective than no further therapy for treating…
- Trial name
- NCT00003825
- Testing
- pentosan polysulfate sodium, quality-of-life assessment
- Where
- 260 sites in United States, Canada
- Volunteers
- 174 people
- Sponsor
- Radiation Therapy Oncology Group
Interstitial Cystitis
Effectiveness and Safety Study of Pentosan Polysulfate Sodium for the Treatment of Interstitial Cystitis
The purpose of this study is to evaluate the safety and effectiveness of pentosan polysulfate sodium 100 mg once a day, pentosan polysulfate sodium 100 mg three times a day, and placebo for 24 weeks for the relief of bladder pain…
- Trial name
- NCT00086684
- Testing
- Pentosan polysulfate sodium 100 mg
- Where
- 65 sites in United States, Canada
- Volunteers
- 369 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Osteoarthritis, Knee
A Study to Investigate the Treatment Effect of Subcutaneous Injections of Pentosan Polysulfate Sodium Compared With Placebo in Adult Participants With Knee Osteoarthritis Pain.
The purpose of this study is to measure the change in pain and function with subcutaneous injections of pentosan polysulfate sodium (PPS) compared with subcutaneous injections of placebo in participants with knee OA pain.
- Trial name
- NCT06917404
- Testing
- Pentosan Polysulfate Sodium twice weekly
- Where
- 57 sites in United States, Australia and 2 more
- Volunteers
- 466 people
- Sponsor
- Paradigm Biopharmaceuticals Ltd.