Clinical trials: Outcome Assessment, active
Symptomatic Irreversible Pulpitis (SIP)
Short Term Comparative Assessment of MTA and Biodentine in Complete Pulpotomy for Symptomatic Irreversible Pulpitis
All Patients coming to the Operative Dentistry Department (DIDC-DUHS) with complain of pain in posterior teeth will be invited to participate. The treatment will be done by one dentist.
- Trial name
- NCT07483788
- Testing
- Biodentine pulpotomy
- Where
- 2 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Quality Indicators
Evaluation of Quality Indicators in Patients Receiving Intensive Care and Their Influence on Outcome Indicators and Economic Indicators
The aim of the study is to identify and evaluate incentive mechanisms for the implementation of quality-relevant care processes.
- Trial name
- EQUINOK (NCT07501494)
- Where
- Germany
- Volunteers
- 35,000 people
- Sponsor
- Charite University, Berlin, Germany
No Disease or Condition is Being Studied
Optimizing Operational Parameters for Diagnostic Vitrectomy
Single-center ex-vivo study using blood samples from healthy donors processed through a 25-gauge vitrectomy system. The study compares four combinations of operational parameters (vacuum pressure and cut rate) to evaluate their…
- Trial name
- CELLVIT (NCT07408466)
- Testing
- Simulated vitrectomy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Acute Ischemic Stroke (AIS)
Tirzepatide in Thrombectomy-Treated Acute Ischemic Stroke: A Randomized Trial
Acute ischemic stroke caused by blockage of a large artery in the brain is one of the leading causes of death and long-term disability worldwide.
- Trial name
- TOPAZ (NCT07734792)
- Testing
- Tirzepatide, Standard Medical Care (SMC)
- Where
- China
- Volunteers
- 726 people
- Sponsor
- yifang zhu
Dental Caries, Cervical Caries
The Effectiveness RMGI and Giomer, Individually and Combined Anterior Cervical Caries
This study compares the effectiveness of three dental materials for restoring anterior cervical caries in high-risk patients: resin-modified glass ionomer (RMGI), Giomer, and a combination technique where RMGI is veneered with…
- Trial name
- NCT06901453
- Testing
- Low shrinkage Giomer restorative material (Beautifil II LS), RMGI alone - Control
- Volunteers
- 75 people
- Sponsor
- Cairo University
Fertility, Fecundability
Physical Activity, Fertility, and Spontaneous Abortion in Danish Couples Trying to Conceive
Physical activity in both the preconception period and during pregnancy may enhance the probability of getting pregnant and reduce the risks of complications during pregnancy.
- Conditions
- Fertility, Fecundability, Time-to-Pregnancy, Spontaneous Abortion
- Trial name
- SF/Activity (NCT06705712)
- Testing
- Use of activity trackers and motivational conversations to enhance focus on physical activity among women trying to conceive.
- Where
- Denmark
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Acute Stroke, Ischemic Stroke
Impact of Stroke Unit Care on Acute Stroke Outcomes
This observational study is designed to evaluate and compare the recovery outcomes of patients who have experienced their first acute stroke.
- Conditions
- Acute Stroke, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- NCT07750860
- Volunteers
- 140 people
- Sponsor
- Assiut University
Multi Drug Resistant Tuberculosis, HIV Infections
An Adaptive Randomized Controlled Trial
This is a prospective, adaptive, randomized controlled trial comparing the effectiveness of 4 intervention arms on a combined endpoint in adults with confirmed MDR-TB HIV initiating Bedaquiline-containing MDR-TB treatment…
- Trial name
- ADAP-TIV (NCT05633056)
- Testing
- Adherence support intevention
- Where
- South Africa
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Columbia University
Urology, Urological Diseases
RUTISS-Diary and RUTISS-65 Study
Existing patient-reported outcome measures assess acute urinary tract infection but do not support daily symptom tracking in recurrent UTI (rUTI) or meet the needs of older adults.
- Conditions
- Urology, Urological Diseases, Patient Satisfaction, Pain, Chronic
- Trial name
- NCT07698041
- Testing
- Non-interventional Patient Reported Outcome Measure Development (RUTISS-Diary), Non-interventional Patient Reported Outcome Measure Development (RUTISS-65)
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- Katherine Finlay
Mental Illness, Psychiatric Disorder
Process and Outcome Evaluation of Different Psychotherapies
In this study, adult patients and therapists at the Outpatient Clinic for Psychotherapy of the Paris Lodron University Salzburg will complete questionnaires throughout the course of psychotherapy in order to evaluate the course…
- Conditions
- Mental Illness, Psychiatric Disorder, Mental Disorder
- Trial name
- NCT06538675
- Testing
- Psychotherapy
- Where
- Austria
- Volunteers
- 120 people
- Sponsor
- University of Salzburg
Bradycardia, Pacing
"Physiological vs Right Ventricular Pacing Outcome Trial Evaluated for bradyCardia Treatment" (PROTECT-HF)
The PROTECT-HF multi-centre randomised controlled trial will compare two different pacing approaches for treating patients with slow heart rates.
- Conditions
- Bradycardia, Pacing, Right Ventricular Pacing, His Bundle Pacing
- Trial name
- PROTECT-HF (NCT05815745)
- Testing
- Pacemaker - Physiological pacing, Pacemaker - Right Ventricular pacing
- Where
- 45 sites in Ireland, Slovenia and 1 more
- Volunteers
- 2,600 people
- Sponsor
- Imperial College London
Communication Aids for Disabled, Communication Disorders
Outcomes of ICT Assistive Technology in RehabiliTAtIoN Pathways
The study aims to improve the quality of prosthetic intervention and verify the adequacy of assistive devices, and measurement outcomes.
- Conditions
- Communication Aids for Disabled, Communication Disorders, Motor Disorders, Cognitive Disorder
- Trial name
- ATTAIN (NCT06546813)
- Testing
- scales and questionnaire administration
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Chronic Graft Versus Host Disease
Improving Outcomes Assessment in Chronic GVHD
The purpose of this study is to see if recent guidelines proposed by the National Institutes of Health for the diagnosis, staging, and response assessment of people with chronic GVHD can improve our understanding of this…
- Trial name
- NCT00637689
- Where
- 9 sites in United States
- Volunteers
- 601 people
- Sponsor
- Fred Hutchinson Cancer Center
STROKE, Rehabilitation Outcome
Prospective Evaluation of Atrial Fibrillation-Related Stroke Patients in Rehabilitation Program (PEARL), an Observational Cohort Study
The goal of this observational study is to determine if rehabilitation program intensity impacts functional recovery and specific needs in adult ischemic stroke patients who require inpatient rehabilitation.
- Conditions
- STROKE, Rehabilitation Outcome, Brain Disease, Cardiovascular Disease Acute
- Trial name
- PEARL (NCT07253974)
- Testing
- Rehabilitation program based on Physiotherapy, occupational therapy and swallow and language therapy
- Where
- Spain
- Volunteers
- 213 people
- Sponsor
- Parc de Salut Mar
Rehabilitation, Excercise
The ACT-ON: A Geriatric 5-Ms-Guided Physical Therapy Intervention for Knee Osteo-Arthritis in Older Adults.
The study is a Random control trail study conducted at King Khalid University Hospital in Riyadh, Saudi Arabia, focusing on Application of 5 framework in rehabilitation program of knee arthritis.
- Conditions
- Rehabilitation, Excercise, Geriatric, Physical Therapy
- Trial name
- 5Ms/PT/KOA/OA (NCT07640529)
- Testing
- Geriatric 5Ms framework, Exercises PT
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- King Saud University
COPD Exacerbation, ICU
Characteristics and Outcomes of Patients Admitted to ICU for a Severe Acute Exacerbation of COPD.
The objective of this prospective observational study is to describe the epidemiological, clinical and biological characteristics of patients admitted in ICU for a severe acute exacerbation of COPD, and to assess the different…
- Trial name
- COPDregister (NCT06257329)
- Testing
- register
- Where
- 4 sites in France
- Volunteers
- 2,000 people
- Sponsor
- Alexis FERRE
Bone Neoplasms, Soft Tissue Neoplasms
Stress and Anxiety Before Biopsy, After Biopsy Results, and During Treatment in Patients With Suspected Bone or Soft Tissue Cancer
This prospective observational study will follow adults who are scheduled for a clinically indicated biopsy because of a suspected solid tumor involving bone or soft tissue.
- Conditions
- Bone Neoplasms, Soft Tissue Neoplasms, Anxiety, Stress, Psychological
- Trial name
- BIOPSY-STRESS (NCT07727434)
- Testing
- Routine Diagnostic and Treatment Pathway
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University
Post-partum Hemorrhage
REBOA in Life-threatening Postpartum Hemorrhage (PPH) in Uganda
Background Maternal mortality rates in many low-income countries (LMICs) remain high. The most prominent cause is bleeding after birth, called postpartum haemorrhage (PPH).
- Trial name
- REBOA-PPH (NCT05598502)
- Testing
- REBOA, Resuscitative Endovascular Occlusion of the Aorta, National guidelines
- Where
- Uganda
- Volunteers
- 95 people
- Sponsor
- Centre For International Health
Lymphatic Malformation, Generalized Lymphatic Anomaly (GLA)
Lymphatic Anomalies Registry for the Assessment of Outcome Data
Lymphatic anomalies are a rare subset of vascular anomalies that are poorly understood. the understanding of the natural history, long-term outcomes, risk factors for morbidity and mortality, and the relative benefit of medical…
- Conditions
- Lymphatic Malformation, Generalized Lymphatic Anomaly (GLA), Central Conducting Lymphatic Anomaly, CLOVES Syndrome
- Trial name
- NCT02399527
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Boston Children's Hospital
Functional Impairment, Frailty
A Partnered Evaluation to Improve the Identification and Management of Functional Impairment and Frailty Among Older Veterans in Primary Care Settings
Maintaining functional status, or the ability to perform daily activities, is central to older adults' quality of life, health, and ability to remain independent.
- Trial name
- NCT06404970
- Testing
- Screening intervention, Standard bundle of implementation strategies, Enhanced bundle of implementation strategies
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- VA Office of Research and Development