Clinical trials: Outcome Assessment
Osteoarthritis
Precision Assessment of Platelet Rich Plasma for Joint Preservation
Knee Osteoarthritis (OA) is a leading cause of premature disability in Veterans who develop knee OA at higher rates and younger ages than the population in general.
- Trial name
- NCT03460236
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- VA Office of Research and Development
Newborn, Infant, Disease, Neurodevelopmental Disorders
Perinatal Covid-19 Infection, NO Pathway, and Minipuberty
Some evidence exists that SARS-COV-2 may infect pituitary axis, and therefore may alter hypothalamic function. Whether perinatal COVID-19 is associated with alterations in the maturation of the Hypothalamic-Pituitary-Gonadal…
- Trial name
- miniNO-COVID (NCT04952870)
- Testing
- Inhaled NO, routine care
- Where
- 2 sites in France, Greece
- Volunteers
- 180 people
- Sponsor
- University Hospital, Lille
Stroke
Pre-stroke Physical Activity in Patients With Stroke
The aim of this study is to explore the level of pre-stroke physical activity in patients with stroke and to investigate associations between physical activity and sociodemographic variables, e.g.
- Trial name
- NCT05051111
- Where
- Denmark
- Volunteers
- 123 people
- Sponsor
- Herlev Hospital
Thrombosis in Children
Evaluation of Risk Factors and Outcome of Thrombosis in Children
Pediatric thrombosis is multifactorial, and usually risk factors either congenital or acquired are present. Patient may has one risk factor or more such as sepsis, cancers, congenital heart disease, post surgery , central venous…
- Trial name
- NCT05840744
- Testing
- complete blood count
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Unrecognized Condition
A 15-year Single Center Experience of Endovascular Treatment of Transplant Renal Artery Stenosis
Stenosis of the renal graft arteries occurs in 1 to 26% of cases and can damage the graft. Endovascular treatment is first-line treatment.
- Trial name
- NCT03477071
- Testing
- Angioplasty for Transplant Renal Artery Stenosis (TRAS)
- Volunteers
- 1,323 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Stroke, Acute, Cerebrovascular Disorders
Therapy Evaluation in Patients With Minor Stroke and Large Vessel Occlusion
This multicenter registry study, which record the therapy strategy and follows up these acute ischemic stroke (AIS) patients with low NIHSS and large vessel occlusion (LVO), is intended to provide the important data for therapy…
- Conditions
- Stroke, Acute, Cerebrovascular Disorders, Brain Diseases, Central Nervous System Diseases
- Trial name
- TEMPOS (NCT06633809)
- Testing
- Immediate endovascular therapy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sir Run Run Shaw Hospital
Apicomarginal Defects
Effect of Combined Use of an Allograft and Membrane on the Healing Outcome of Apicomarginal Defects
Healing of apicomarginal defects using 2 different groups, one being treated with the use of an allograft and a membrane and a control group, will be assessed and compared using 2D and 3D criteria.
- Trial name
- NCT05171543
- Testing
- Periapical surgery with placement of an allograft and a membrane
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Colorectal Cancer
A Trial to Evaluate Laparoscopic Versus Open Surgery for Colorectal Cancer
The purpose of this study is to evaluate oncological outcome of patients for T3 and T4 colorectal cancer undergoing laparoscopic versus open surgery.
- Trial name
- NCT00147134
- Testing
- open colectomy, laparoscopic colectomy
- Where
- 26 sites in Japan
- Volunteers
- 1,050 people
- Sponsor
- Haruhiko Fukuda
COVID-19
Immune Biomarkers of Outcome From COVID-19
A new virus to humans, first identified in December 2019, is causing a global pandemic with over 1 million infections and many thousands of deaths.
- Trial name
- IBOC (NCT04436484)
- Testing
- Peripheral blood sampling
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- University Hospital Plymouth NHS Trust
Simple Biceps Tenotomy, Anchor Tenotomy
Comparison Between Arthroscopic Simple Biceps Tenotomy & Anchor Technique Tenotomy with Clinical and Ultrasound Assessment
Comparison between arthroscopic simple biceps tenotomy \& anchor tenotomy technique regarding clinical outcomes \& ultrasound assessment
- Trial name
- NCT06833398
- Testing
- Arthroscopic Simple Biceps Tenotomy:, Anchor Tenotomy Technique:
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Assiut University
Radiology, Inflammatory Bowel Diseases
CT Using MBIR in Crohn's Disease: Prospective Clinical Evaluation of Diagnostic Efficacy, Safety and Patient Outcome.
This study aims to assess the use of low dose CT reconstructed with MBIR for the assessment of patients with inflammatory bowel disease who need CT to assess for disease complications.
- Trial name
- NCT03140306
- Testing
- Patients who have had split dose CT
- Where
- Ireland
- Volunteers
- 56 people
- Sponsor
- University College Cork
Stroke, Ischemic, Thrombectomy
Prognostic Value of Isolated and Combined Score Aspects in Acute Ischemic Stroke
This study, called TARGET-ASPECT, looks at patients who had a type of stroke called acute ischemic stroke and were treated with clot-busting medicine and a procedure to remove the clot.
- Conditions
- Stroke, Ischemic, Thrombectomy, Thrombolytic Therapy, Brain Ischemia
- Trial name
- NCT07069452
- Where
- France
- Volunteers
- 152 people
- Sponsor
- Centre Hospitalier de Gonesse
Heart Failure With Reduced Ejection Fraction (HF-rEF)
Study of Efficacy and Safety of LCZ696 in Japanese Patients With Chronic Heart Failure and Reduced Ejection Fraction
The purpose of this study was to assess the effect of LCZ696 at a target dose of 200 mg b.i.d. compared to enalapril 10 mg b.i.d., in addition to the background heart failure (HF) treatment, on delaying time to first occurrence…
- Trial name
- PARALLEL-HF (NCT02468232)
- Testing
- LCZ696, Enalapril
- Where
- 49 sites in Japan
- Volunteers
- 225 people
- Sponsor
- Novartis Pharmaceuticals
Renal Carcinoma Metastatic, Kidney Neoplasms
Quality of Life Assessment in Daily Clinical Oncology Practice for Patients With Advanced Renal Cell Carcinoma
Physician mainly use RECIST progression-free survival (PFS) and NCI CTCAE safety as a guide to evaluate treatment efficiency. In contrast Health Related Quality of Life (HRQOL) assessment is often restricted to clinical trial.
- Conditions
- Renal Carcinoma Metastatic, Kidney Neoplasms, Renal Cancer
- Trial name
- QUANARIE (NCT03062410)
- Testing
- Electronic PRO in daily clinical practice
- Where
- 8 sites in France
- Volunteers
- 56 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Total Knee Replacement
Qualitative Interviews With Healthcare Professionals
PLANNING PHASE- Qualitative interviews with Healthcare Professionals to assist in the development of a new Patient Reported Outcome Measure (PROM) to assess patient's emotional wellbeing, and perceptions of Total Knee Replacement…
- Trial name
- NCT05597046
- Testing
- Interview
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Invibio Ltd
Sarcoma of Bone, Sarcoma of Soft Tissue
Retrospective Study in Sarcoma Patients
The objectives of this trial is to evaluate efficacy and safety of treatment with Trabectedin in a large cohort of German patients with soft tissue and bone sarcomas.
- Trial name
- ReTraSarc (NCT03284320)
- Where
- Germany
- Volunteers
- 514 people
- Sponsor
- University Medicine Greifswald
Surgical Site Infection
Tracking Wound Infection With Smartphone Technology
This study aims to evaluate if a smartphone-delivered tool can help assess for wound infections, and if this improves access to care and results in earlier treatment. Participants will be randomised to one of two groups.
- Trial name
- TWIST (NCT02704897)
- Testing
- Wound Assessment Tool
- Where
- 2 sites in United Kingdom
- Volunteers
- 492 people
- Sponsor
- University of Edinburgh
Analgesia, Children, Only
The Use of Midazolam as Adjuvant to Bupivacaine Intrathecal Anesthesia for Children Undergoing Lower Abdominal Surgeries.
The study will be carried on children undergoing lower abdominal surgeries. Patients will be randomly categorized into two study groups.
- Conditions
- Analgesia, Children, Only, Bupivacaine, Midazolam
- Trial name
- NCT04718259
- Testing
- intrathecal bupivacaine, midazolam
- Where
- Saudi Arabia
- Volunteers
- 120 people
- Sponsor
- Tanta University
Chronic Low Back Pain
Validation of the Evaluation of the Perception of Physical Activity Questionnaire Adapted to Chronic Low Back Pain
Physical exercise has a fundamental position in the chronic low back pain treatment. However, the physical activity level is often low in these patients and the adherence to the care program is not enough in the long term.
- Trial name
- EPAP-LOMB (NCT05942196)
- Where
- France
- Volunteers
- 99 people
- Sponsor
- University Hospital, Clermont-Ferrand
Heart Failure
Study of China Heart Failure Registry to Investigate Characteristics of Patients in China
The purpose of this study is to assess clinical characteristics, treatment, and outcome of patients hospitalized with heart failure in China and compared those with other registries
- Trial name
- China-HF (NCT02664818)
- Where
- China
- Volunteers
- 15,000 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
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