Clinical trials: Osteoporotic Fracture of Femur
Osteoporosis, Postmenopausal, Osteoporosis Fracture
New Biomarkers and Therapeutic Targets in Osteoporosis Via Omics Technologies
This study aims to discover novel biomarkers and therapeutic targets for osteoporosis through the use of advanced omics technologies, including proteomics and metabolomics.
- Conditions
- Osteoporosis, Postmenopausal, Osteoporosis Fracture, Osteoporosis, Severe
- Trial name
- NCT06525688
- Testing
- Bone, Serum and Plasma sample
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- National and Kapodistrian University of Athens
Proximal Femur Fracture
Evaluation of the Proximal Femoral Nail Antirotation With Cement Augmentation in Osteoporotic Femoral Neck Fractures
This is an open multicenter study, evaluating a new operative technique in femur neck fractures. The treatment consist of augmentated nails in cases of subtrochanteric or inter fracture due to osteoporosis.There two routine…
- Trial name
- NCT01235169
- Testing
- Proximal Femoral Nail Antirotation(PFNA) with cement augmentation
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Fragility Fracture, Hip Fractures
RESTORE - Study of AGN1 LOEP to Prevent Secondary Hip Fractures
A randomized controlled trial to evaluate AGN1 to prevent secondary hip fractures in osteoporotic women undergoing treatment of index hip fractures.
- Conditions
- Fragility Fracture, Hip Fractures, Osteoporosis
- Trial name
- NCT04796350
- Testing
- AGN1 LOEP treatment
- Where
- 66 sites in Austria, Belgium and 9 more
- Volunteers
- 2,400 people
- Sponsor
- AgNovos Healthcare, LLC
Atypical Femur Fracture
Quebec Registry for Atypical Femur Fractures
Bisphosphonates are recommended as first-line agents to reduce fracture risk in patients with osteoporosis and have in general an excellent safety profile.
- Trial name
- NCT02150850
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- McGill University
Femoral Neck Fractures
Study of A Special Vessel Subtype in Bone Samples From Patients With Osteoporotic and Nonosteoporotic Fracture
RATIONALE: Collecting and storing bone samples from patients with osteoporotic and nonosteoporotic fracture to study a special vessel subtype in the laboratory may help surgeon learn more about the relationship between bone…
- Trial name
- NCT02750046
- Testing
- total hip arthroplasty or proximal femoral nails
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Hip Fracture
Study of Low-Magnitude, High-Frequency Vibration Treatment on Osteoporotic Hip Fracture Healing
Osteoporotic hip fracture is common in elderly. As a result of aging population in Hong Kong, the total number of hip fracture cases is anticipated to increase substantially in the future, and therefore draw more resources in…
- Trial name
- NCT01293721
- Testing
- Low-magnitude high - frequency vibration treatment
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Chinese University of Hong Kong
Frail Elderly, Hip Fracture
Effects of Long-term Intensive Home-based Physiotherapy on Older People With an Operated Hip Fracture or Frailty (RCT).
Our objective is to study the effects of 12 months' intensive home-based physiotherapy (physical exercise) with 12 months' follow-up in two groups of older people: 1) those with an operated hip fracture (60+ y), and 2) those with…
- Trial name
- HIPFRA (NCT02305433)
- Testing
- Home-based physiotherapy (physical exercise)
- Where
- Finland
- Volunteers
- 421 people
- Sponsor
- South Karelia, Social and Health Care District
Hip Fractures, Fragility Fracture
Iron Supplementation for Geriatric Hip Fractures
Geriatric hip fracture is an important disease that affects the health life of the elderly in China. Geriatric hip fracture is often complicated by a variety of comorbidities due to advanced age.
- Conditions
- Hip Fractures, Fragility Fracture, Osteoporotic Fractures
- Trial name
- NCT05489952
- Testing
- iron sucrose and ferrous lactate
- Where
- China
- Volunteers
- 444 people
- Sponsor
- He Qifei
Sepsis, Osteoporotic Hip Fracture
Prediction of Mortality and Morbidity After Hip Fracture Using Monocyte Distribution Width (MDW)
Hip fracture is a common injury in older adults and is often associated with serious complications, longer hospital stays, and increased risk of death.
- Conditions
- Sepsis, Osteoporotic Hip Fracture, Hip Fracture
- Trial name
- MDW (NCT07350785)
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- National and Kapodistrian University of Athens
Osteoporotic Fractures, Hip Fractures
Prediction and Secondary Prevention of Fractures
The purpose of this study is to investigate patient related factors that contribute to increased risk of recurrent fractures and to investigate patient adherence to prescribed anti-osteoporotic drugs.
- Conditions
- Osteoporotic Fractures, Hip Fractures, Wrist Fractures, Ankle Fractures
- Trial name
- NOFRACTsub (NCT02608801)
- Where
- 6 sites in Norway
- Volunteers
- 840 people
- Sponsor
- Oslo University Hospital
Healthy, Osteopenia
Clinical Study to Estimate Bone Mineral Density With the POROUS Ultrasound Device
Osteoporosis is a widespread medical condition among older people. It causes the bones to weaken and become more likely to break.
- Conditions
- Healthy, Osteopenia, Osteoporosis
- Trial name
- POROUS-BMD (NCT07187518)
- Testing
- Measurements with the POROUS R4C ultrasound device at the midshaft tibia, DXA measurement of the hip and lumbar spine
- Where
- 2 sites in Germany
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- POROUS GmbH
Fracture; Pelvic, Insufficiency Fractures
Real World Evidence of SI-BONE's iFuse TORQ TNT Advancing Treatment of Pelvic Ring Fractures
The purpose of this study is to evaluate outcomes in patients treated with iFuse TORQ TNT for pelvic fragility fractures.
- Conditions
- Fracture; Pelvic, Insufficiency Fractures, Fragility Fracture, Sacroiliac; Fusion
- Trial name
- REBAR (NCT07530497)
- Testing
- iFuse TORQ TNT Implant System
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- SI-BONE, Inc.
Hip Fractures, Osteoporotic Fractures
Secondary Fracture Prevention in Patients Who Suffered From Osteoporotic Fracture
Due to its prevalence worldwide, osteoporosis is considered a serious public health concern. The worldwide annual incidence of Osteoporotic fractures is approximately 2 million in the US only.
- Conditions
- Hip Fractures, Osteoporotic Fractures, Osteoporosis
- Trial name
- NCT02223572
- Testing
- hip Xray
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- pninarotman
Osteoporosis, Diet Habit
Soft Drinks and Osteoporosis in WHI Participants
Osteoporotic fractures, as a consequence of a reduced mineral bone density (BMD) represents a major public health problem. The lifetime risk of fractures exceeds 40% for women and 13% for men.
- Trial name
- NCT03371433
- Testing
- Soft drinks
- Volunteers
- 79,885 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Osteopenic Women, Proximal Femur Fracture
Copley II: Long-term Outcome Follow-up Study of Osteoporotic Women Who Underwent a Local Osteo-Enhancement Procedure (LOEP) in the Proximal Femur
To evaluate longer-term (5-7 years) outcomes of the twelve (12) subjects treated with AGN1 Femoral LOEP in the clinical study "A Prospective Pilot Evaluation of Percutaneous Osteo-supplementation in the Proximal Femur of…
- Trial name
- NCT06799143
- Volunteers
- 12 people
- Sponsor
- AgNovos Healthcare, LLC
Hip Fractures, Osteoporotic Fractures
Fixation Methods of Basicervical Fractures
This prospective, randomized study included patients aged over 65 years with basicervical fracture of femur from January 2016 to January 2018.
- Trial name
- NCT04240743
- Testing
- cephalomedullary nail, sliding hip screw
- Volunteers
- 64 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Osteoporotic Fractures, Femoral Neck Fracture
Short-term Functional Recovery Between Early- and Late Bisphosphonate Treatment Following Hemiarthroplasty
Femoral neck fracture in the elderly is one indication for initiating osteoporosis treatment. Bisphosphonates remain the first line therapy; however, many orthopaedic surgeons concern regarding their effects on fracture healing…
- Trial name
- NCT02148848
- Testing
- Risedronate
- Where
- Thailand
- Volunteers
- 86 people
- Sponsor
- Mahidol University
Osteoporosis
GRACE - Study of AGN1 LOEP in Osteopenic and Osteoporotic Patients
The study is designed as a retrospective, single-center study for subjects previously treated with the AGN1 LOEP Kit. This will be a non-randomized and non-blinded study.
- Trial name
- NCT05966974
- Where
- Belgium
- Volunteers
- 44 people
- Sponsor
- AgNovos Healthcare, LLC
Hip Fractures, Osteoporosis
Secondary Prevention of Osteoporotic Fractures in Residents of Long-Term Care Facilities
Osteoporotic fractures of the hip are a major cause of admission to long-term care facilities. Such fractures put patients at high risk for further fractures, pain and disability.
- Trial name
- NCT00280943
- Testing
- Long-term care facilities in the intervention arm will receive education and feedback audit on performance
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Duke University
Hip Fractures
Geriatric Fracture Centers - Evaluation of a Geriatric Co-management Program
The study will assess patients with at least one major AE related to treatment / hospitalization / immobilization in the Geriatric Fracture Center (GFC) group compared to the usual care group.
- Trial name
- NCT02297581
- Where
- 12 sites in United States, Austria and 4 more
- Volunteers
- 282 people
- Sponsor
- AO Innovation Translation Center