Clinical trials: Osseointegration
Jaw, Edentulous
Release of Osteogenic Markers in Immediately and Non-loaded Dental Implants
The aim of this study was to compare the release of the osteoprotegerin (OPG), transforming growth factors (TGF-α), osteocalcin (OCN), osteopontin (OPN), and parathyroid hormone (PTH) during osseointegration of dental implants…
- Trial name
- NCT01909999
- Testing
- Osteogenic markers Evaluation, Clinical parameters evaluation, Implant instalation
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Renato Correa Viana Casarin
Patients With Missing Teeth
Platelet Rich Fibrin Versus Melatonin Around Dental Implants
Dental implant is a dental treatment that allow oral rehabilitation for partial and fully edentulous patients. Osteointegration is the factor that control success s or failure of dental implant that can be improved by addition of…
- Trial name
- NCT05593731
- Testing
- dental implants with melatonin gel
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Osseointegration
Erythropoietin Gel Effect on Dental Implant Stability
Achieving and maintaining long-term osseointegration for dental implants is a key objective in the field of dentistry. The success of osseointegration is influenced by the surface treatment applied to dental implants.
- Trial name
- NCT06665451
- Testing
- Non coated dental implants, Erythropoietin gel coated implants
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Implant Failed, Pre-osseointegration Failure of Dental Implant
Evaluation of the Stability of Implants With Two Different Surface Treatments
The aim of this study is to compare the stability of dental implant surface treated by sandblasting abrasive particles and acid subtraction (Control) with hydrophilic surfaces dental implants (chemical) and with a higher surface…
- Trial name
- NCT02134743
- Testing
- Implant surgery
- Where
- Brazil
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Jaw, Edentulous, Dental Implant
An Implant With an Acid-etched Fixture Surface and Internal-hex Collar May Achieve Greater Osseointegration.
Brånemark System® dental implant osseointegration was introduced clinically in 1965 as a novel approach to the replacement of missing teeth.
- Trial name
- NCT01641198
- Testing
- Configuration 1, Configuration 2, Configuration 3
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Immediate Dental Implant
Immediate Implants in the Aesthetic Zone
The use of immediate implants in the aesthetic area is a technique widely used in modern implantology. The characteristics of the patient, the implant, and the surgical procedure used may influence the final results.
- Trial name
- NCT04343833
- Testing
- Immediate dental implants
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Severe Maxillary Atrophy
Assessment of Bone Density Following Application of BMAC Around Zygomatic Implant
This prospective case series is designed to evaluate the effect of autologous bone marrow aspirate concentrate applied around zygomatic implants placed via the intrasinus approach.
- Trial name
- BMAC (NCT07657026)
- Testing
- zygomatic implants placement
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Cairo University
Dental Implants, Surface Treatment
Surface Treatment of the Dental Implant on the Osseointegration
Dental implants have become a widely accepted treatment modality for the replacement of missing single or multiple teeth in the recent years.
- Trial name
- NCT05194813
- Testing
- Aqua alvim CM, neodent implant (Test), Neoporous alvim CM, neodent implant (Control)
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Hams Hamed Abdelrahman
Tooth Loss, Surface Treatment
Effect of Different Loading Protocols on Photofunctionalized Implants in the Posterior Maxilla
This randomized clinical trial evaluates different loading protocols for UV-photofunctionalized dental implants in the posterior maxilla. Clinical and radiographic outcomes will be assessed during follow
- Conditions
- Tooth Loss, Surface Treatment, Immediate Dental Implant Loading, Implant Loading
- Trial name
- PHOTOLOAD (NCT07700914)
- Testing
- Immediate loading of UV-photofunctionalized dental implants, Early loading of UV-photofunctionalized dental implants, Conventional loading of UV-photofunctionalized dental implants
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Alveolar Ridge Augmentation, Dental Implants
A Clinical Study of the Use of Brushite as Primary Stabilizer in Immediate Dental Implantation
Objective: The evaluation of "PD" VitalOs Cement, an injectable brushite, as a stabilizer of dental implants and a potential source for bone augmentation.
- Trial name
- NCT00299585
- Testing
- using "PD" VitalOs Cement with dental implants
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
X-linked Hypophosphatemia
Dental Implants in Patients With X-linked Hypophosphatemia
X-linked hypophosphatemia (XLH) is a rare genetic skeletal disease where increased phosphate wasting in the kidney leads to hypophosphatemia and prevents normal mineralization of bone and dentin, with osteomalacia as a principal…
- Trial name
- IMPLANTS-XLH (NCT03879915)
- Testing
- Dental Implant placement
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Osseointegration Failure of Dental Implant
A Randomised Control Clinical Trial Investigating the Effect of H-PRF on Implant Stability and Marginal Bone Levels
This research will be a randomised controlled trial (RCT) investigating whether the use of Horizontal Platelet Rich Fibrin (H-PRF) increases implant stability compared to those implants placed without H-PRF, and therefore…
- Trial name
- NCT06453330
- Testing
- Horizontal platelet-rich fibrin (H-PRF)
- Where
- Ireland
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Different Surgical Techniques in Dental Implant Surgery
Effect of Different Drilling Techniques on Primary Stability and Marginal Bone Loss of Extra Short Implants
Our aim in this study is to compare the effects of low-speed drilling surgery technique without irrigation and conventional implant surgery technique with irrigation on extra short implants.
- Trial name
- NCT06234566
- Testing
- Conventional dental implant surgery, Low Speed Drilling Without Irrigation
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Erzincan University
Dental Implantation
Evaluation Of The Effect Of Surface Properties On The Stabılıty Of The Different Implants
This randomised clinical study aims to evaluate different surfaced implants (alkali-modified surfaced implants or sand-blasted surfaced implants) stability with resonance frequency analysis(RFA).
- Trial name
- Surface (NCT03915509)
- Testing
- Evaluation of the effect of surface properties on the stability of the different implants with resonance frequency analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Dental Implants, Immediate Implant Placement
Autologous Demineralized Dentin Graft With or Without Melatonin for Immediate Implant Osseointegration
This randomized clinical study aims to evaluate the effect of autologous demineralized dentin graft (ADDG) with or without melatonin gel on the osseointegration of immediately placed dental implants in the maxillary premolar…
- Conditions
- Dental Implants, Immediate Implant Placement, Osseointegration
- Trial name
- NCT07610876
- Testing
- Autologous Demineralized Dentin Graft, Melatonin gel
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Jaw, Edentulous
Peri-Implant Healing Around Two Different Machined-Collar Designs After 25 Years of Function
Brånemark System® dental implant osseointegration was introduced in 1965 as a novel approach to the replacement of missing teeth.
- Trial name
- NCT03862482
- Testing
- Brånemark® 2, Swede-Vent® 2, Screw-Vent® 1 (Configuration 1), Brånemark® 1, Swede-Vent® 2, Screw-Vent® 2 (Configuration 2), Brånemark® 2, Swede-Vent® 1, Screw-Vent® 2 (Configuration 3)
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Traumatic Amputation of Lower Extremity
Intraosseous Transcutaneous Amputation Prosthesis
Direct Skeletal Fixation of Prosthetic Limbs Following Trans-Femoral Amputation - Study of an Intraosseous Transcutaneous Amputation Prosthesis (ITAPTM).
- Trial name
- (ITAP) (NCT02491424)
- Testing
- Direct skeletal fixation of ITAP to lower limb amputees.
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- Stryker Orthopaedics
Implant Geometry, Osseointegration, Soft Tissue Volume, Marginal Bone Levels, Soft Tissue Recession, Volumetric Analysis
The Influence of a New Implant Neck Configuration on Hard and Soft Tissue Healing
Title: Randomized Controlled Clinical Trial comparing two dental implants with different neck configurations. Objective: To evaluate the changes in peri-implant soft tissues and marginal bone level when using a one-piece implant…
- Trial name
- NCT04308083
- Testing
- dental implant placement
- Where
- Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- PerioCentrum Research
Immediate Dental Implant, Tooth Exratction
Immediate Dental Implant Placed in the Presence of Chronic Inflammatory Periapical Lesions
Compromised teeth with periapical pathologies are removed before dental implant placement and sockets are left to heal. Some clinicians began to immediately place dental implants in fresh extraction sockets associated with…
- Conditions
- Immediate Dental Implant, Tooth Exratction, Periapical; Infection
- Trial name
- NCT05101941
- Testing
- Immediate dental implants
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Hams Hamed Abdelrahman
Amputation
Powered Prosthesis for Use With TF Osseointegration Recipients
The purpose of this study is to evaluate functional mobility, control, and user satisfaction from persons who have an amputation above the knee and have received osseo-integration (OI) and targeted muscle reinnervation (TMR)…
- Trial name
- NCT06160882
- Testing
- Powered Prosthesis Training and EMG data collection, Perform Osseointegration (OI) surgery and Targeted Muscle Reinnervation (TMR)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Shirley Ryan AbilityLab