Tooth LossPHOTOLOADNCT07700914
Effect of Different Loading Protocols on Photofunctionalized Implants in the Posterior Maxilla
A study testing Immediate loading of UV-photofunctionalized dental implants, Early loading of UV-photofunctionalized dental implants and Conventional loading of UV-photofunctionalized dental implants in people with Tooth Loss and Surface Treatment, run by Mansoura University at 1 site in Egypt.
Trial summary
This randomized clinical trial evaluates different loading protocols for UV-photofunctionalized dental implants in the posterior maxilla. Clinical and radiographic outcomes will be assessed during follow Read more about this study
- Who is it for?
- Ages 18 to 60 years
- Conditions the study is for
- Tooth Loss, Surface Treatment, Immediate Dental Implant Loading
- What is being tested?
- Immediate loading of UV-photofunctionalized dental implants, Early loading of UV-photofunctionalized dental implants and Conventional loading of UV-photofunctionalized dental implants
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Jan 2026to Aug 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- • Patients with missed single tooth or multiple teeth in posterior maxilla
- Patients Free from any para-functional habits.
- Patient with Adequate inter-arch relation and inter-occlusal space to accommodate the prosthetic restoration.
- Patient with good oral hygiene.
- Patients Willing to participate in the study's follow-up intervals.
Who cannot join
- • Patients with any local or systemic disease that absolutely contraindicate implant placement or surgery.
- Pregnancy.
- Patients with any pathological lesion or aggressive periodontal disease at the planned surgical site.
- Patients on drugs that could affect bone healing process such as bisphosphonate.
- Smokers.
- Uncooperative patients.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effects of Different Loading Protocols on Photofunctionalized Dental Implants in the Posterior Maxilla: A Randomized Clinical Trial
This randomized clinical trial evaluates different loading protocols for UV-photofunctionalized dental implants in the posterior maxilla. Clinical and radiographic outcomes will be assessed during follow
Read the detailed description
The study compares immediate, early, and conventional loading of UV-photofunctionalized dental implants placed in the posterior maxilla. Implant stability and peri-implant tissue changes will be evaluated clinically and radiographically
- Conditions
- Tooth Loss, Surface Treatment, Immediate Dental Implant Loading, Implant Loading, Implant Placement, UV Dental Implant
- Being tested
- Immediate loading of UV-photofunctionalized dental implants, Early loading of UV-photofunctionalized dental implants, Conventional loading of UV-photofunctionalized dental implants
- Keywords
- UV-photofunctionalization, Dental implants, Posterior maxilla, Immediate loading, Early loading, Conventional loading, Implant stability, Osseointegration, Peri-implant bone changes, Randomized clinical trial
- Medical subject headings
- Tooth Loss
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Immediate loading of UV-photofunctionalized dental implantsProcedure or surgery
Immediate loading of UV-photofunctionalized dental implants placed in the posterior maxilla.
Early loading of UV-photofunctionalized dental implantsProcedure or surgery
Early loading of UV-photofunctionalized dental implants placed in the posterior maxilla.
Conventional loading of UV-photofunctionalized dental implantsProcedure or surgery
Conventional loading of UV-photofunctionalized dental implants placed in the posterior maxilla
| Study group | Role | What they receive |
|---|---|---|
| Study Group 1 | Experimental | It included 20 patients who received UV treated dental implants placed in maxillary posterior region which were immediately loaded within 3 days of implant placement. Receives: Procedure: Immediate loading of UV-photofunctionalized dental implants |
| Study Group 2 | Experimental | It included 20 patients who received UV-treated dental implants in the maxillary posterior region, with early loading performed 4 weeks after implant placement. Receives: Procedure: Early loading of UV-photofunctionalized dental implants |
| Study Group 3 | Experimental | It included 20 patients who received UV treated dental implants placed in maxillary posterior region which were conventionally loaded after 3 months Receives: Procedure: Conventional loading of UV-photofunctionalized dental implants |
What is being measured
The primary outcome is the main question the study is designed to answer.
Implant Stability
Implant stability will be evaluated using Osstell device based on resonance frequency analysis (ISQ values).
Measured: -Immediately after impant placement -immediately after loading -3 months after loading - 6 months after loading
Hard Tissue (peri-implant bone)
Marginal bone loss will be assessed using CBCT measured in mm.
Measured: - Immediately Postoperative (baseline) - 3 months after loading. - 6 months after loading.
Secondary outcomes (2)
Soft Tissue
The peri-implant mucosa will be evaluated for signs of inflammation using the Modified Sulcus Bleeding Index (mSBI).
Measured: At 6 months after loading.
Peri-implant probing depth
Probing depth will be assessed using a calibrated periodontal probe with light pressure and measured in mm.
Measured: At 6 months after loading.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Jul 2026
- Study start1 Jan 2026
- Primary completionJul 2026 (estimated)
- Study completionAug 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Tooth LossStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- Mansoura University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07700914
- Sponsor's protocol ID
- R.26.01.100
- Acronym
- PHOTOLOAD
- Status last verified
- Jul 2026
- First submitted
- 8 Jul 2026
- Last updated
- 14 Jul 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 14 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Different Loading Protocols on Photofunctionalized Dental Implants in the Posterior Maxilla: A Randomized Clinical Trial
- ClinicalTrials.gov ID
- NCT07700914
- Acronym / sponsor ID
- PHOTOLOAD / R.26.01.100
- Conditions
- Tooth Loss, Surface Treatment, Immediate Dental Implant Loading, Implant Loading, Implant Placement, UV Dental Implant
- Keywords
- UV-photofunctionalization, Dental implants, Posterior maxilla, Immediate loading, Early loading, Conventional loading, Implant stability, Osseointegration
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 60 participants (actual)
- Lead sponsor
- Mansoura UniversityUniversity, hospital or other
- Study start
- 1 Jan 2026 (actual)
- Primary completion
- Jul 2026 (estimated)
- Study completion
- Aug 2026 (estimated)
- First posted
- 14 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized clinical trial evaluates different loading protocols for UV-photofunctionalized dental implants in the posterior maxilla. Clinical and radiographic outcomes will be assessed during follow
Detailed description
The study compares immediate, early, and conventional loading of UV-photofunctionalized dental implants placed in the posterior maxilla. Implant stability and peri-implant tissue changes will be evaluated clinically and radiographically
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Study Group 1 | Experimental | Procedure: Immediate loading of UV-photofunctionalized dental implantsIt included 20 patients who received UV treated dental implants placed in maxillary posterior region which were immediately loaded within 3 days of implant placement. |
| Study Group 2 | Experimental | Procedure: Early loading of UV-photofunctionalized dental implantsIt included 20 patients who received UV-treated dental implants in the maxillary posterior region, with early loading performed 4 weeks after implant placement. |
| Study Group 3 | Experimental | Procedure: Conventional loading of UV-photofunctionalized dental implantsIt included 20 patients who received UV treated dental implants placed in maxillary posterior region which were conventionally loaded after 3 months |
Who may qualify
- Ages
- 18 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- • Patients with missed single tooth or multiple teeth in posterior maxilla
Key exclusion criteria (6 listed)
- • Patients with any local or systemic disease that absolutely contraindicate implant placement or surgery.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Immediate loading of UV-photofunctionalized dental implantsImmediate loading of UV-photofunctionalized dental implants placed in the posterior maxilla. | Procedure or surgery | Study Group 1 |
| Early loading of UV-photofunctionalized dental implantsEarly loading of UV-photofunctionalized dental implants placed in the posterior maxilla. | Procedure or surgery | Study Group 2 |
| Conventional loading of UV-photofunctionalized dental implantsConventional loading of UV-photofunctionalized dental implants placed in the posterior maxilla | Procedure or surgery | Study Group 3 |
Primary outcome
Implant Stability
Time frame: -Immediately after impant placement -immediately after loading -3 months after loading - 6 months after loading
Implant stability will be evaluated using Osstell device based on resonance frequency analysis (ISQ values).
Hard Tissue (peri-implant bone)
Time frame: - Immediately Postoperative (baseline) - 3 months after loading. - 6 months after loading.
Marginal bone loss will be assessed using CBCT measured in mm.
2 secondary outcomes
Soft Tissue
Time frame: At 6 months after loading.
Peri-implant probing depth
Time frame: At 6 months after loading.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Jul 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Immediate loading of UV-photofunctionalized dental implants, Early loading of UV-photofunctionalized dental implants and Conventional loading of UV-photofunctionalized dental implants in people with Tooth Loss and Surface Treatment, run by Mansoura University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 14 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Implant Stability (time frame: -Immediately after impant placement -immediately after loading -3 months after loading - 6 months after loading). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Jul 2026.