Clinical trials: Obsessive Compulsive Personality Disorder
Anxiety
Youth Mayo Clinic Anxiety Coach Randomized Controlled Trial
This research study aims to test the feasibility and effectiveness of using the Mayo Clinic Anxiety Coach smartphone app as an addition to traditional therapy for the treatment of anxiety disorders in youth, particularly those…
- Trial name
- NCT02205203
- Testing
- Mayo Clinic Anxiety Coach, Treatment as Usual
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- Stephen Whiteside
Obsessive-Compulsive Disorder
Cognitive Training in Obsessive Compulsive Disorder
This unique study will allow us to observe the neural correlates associated with working memory in an obsessive compulsive disorder (OCD) paradigm.
- Trial name
- CTOCD (NCT02818088)
- Testing
- n-Back (Cognitive Training)
- Where
- South Africa
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Stellenbosch
Obsessive Compulsive Disorder (OCD)
Neuropsychological Profiles of Pediatric Obsessive Compulsive Disorder (OCD)
The neuropsychological profiles of children treated with standard CBT for OCD are evaluated.
- Trial name
- NCT02160431
- Testing
- CBT for pediatric OCD
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Texas at Austin
Obsessive-compulsive Disorders and Symptoms in Children
Task Control Circuit Targets for Obsessive Compulsive Behaviors in Children
This study will use magnetic resonance imaging (MRI) to assess the function and structure of overlapping task control circuits in children with a range of Obsessive-Compulsive symptoms (OCS).
- Trial name
- NCT03584945
- Testing
- Cognitive Behavioral Therapy, Community Referral as appropriate
- Where
- 2 sites in United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Obsessive-Compulsive Disorder
Tolcapone in Obsessive Compulsive Disorder
The proposed study will consist of a 5-week double-blind cross-over study trial of tolcapone in 20 people (ages 18-65). The study will be divided into an initial 2 week phase and a second 2 week phase, with one of the 2 week…
- Trial name
- NCT03348930
- Testing
- Tolcapone 200 MG
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Chicago
Social Anxiety Disorder, Specific Phobia
Building an Outcomes Assessment Infrastructure to Assess Anxiety Treatment
The collection of patient self-report and diagnostic data will allow us to examine the efficacy of the treatment delivered in the McLean Anxiety Mastery Program.
- Conditions
- Social Anxiety Disorder, Specific Phobia, Separation Anxiety Disorder, Panic Disorder
- Trial name
- NCT02305537
- Testing
- McLean Anxiety Mastery Program
- Where
- United States
- Volunteers
- 559 people
- Sponsor
- Mclean Hospital
Obsessive-compulsive Disorder
Evaluating the Feasibility, Safety and Efficacy of Psychotherapy Assisted Psilocybin for Treatment of Severe OCD
Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder characterized by recurrent distressing thoughts and substantial anxiety, accompanied by repetitive behaviors or mental rituals.
- Trial name
- NCT04882839
- Testing
- psychotherapy assisted psilocybin
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Beersheva Mental Health Center
Obsessive-compulsive Disorder
Efficacy and Adverse Events of Bilateral Single-shot VC/VS Gamma Capsulotomy for OCD: a Pilot Study
Up to 40% of Obsessive-Compulsive Disorder (OCD) patients do not respond to conventional treatments (medications or behavior therapy). For some of them, a neurosurgical treatment can be indicated.
- Trial name
- NCT02433886
- Testing
- Gamma Ventral Capsulotomy
- Where
- Brazil
- Volunteers
- 5 people
- Sponsor
- University of Sao Paulo General Hospital
Obsessive-Compulsive Disorder
Translational Approach to the Understanding and Treatment of Obsessive-Compulsive Disorder (OCD). Can D-Cycloserine Enhance and Stabilize the Treatment-response in Relapsed and Non-responding OCD-patients?
In this randomized controlled trial (RCT) the investigators experimentally test if patients with Obsessive-Compulsive Disorder (OCD) who have received treatment with exposure and response prevention (ERP), but either relapsed or…
- Trial name
- NCT02656342
- Testing
- D-Cycloserine
- Where
- 14 sites in Norway
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Anxiety Disorders in Youth With Autism, Asperger's Syndrome, and Pervasive Developmental Disorder Not Otherwise Specified
Cognitive Behavioral Therapy (CBT) for Anxiety Disorders in Autism: Adapting Treatment for Adolescents
Comorbid anxiety disorders affect as many as 80% of youth with autism spectrum disorders, causing substantial distress and impairment over and above the autism spectrum diagnosis alone.
- Trial name
- NCT01177969
- Testing
- Cognitive-Behavioral Therapy, Wait-list
- Where
- 2 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Obsessive-Compulsive Disorder
Effectiveness of Accelerated Deep TMS in OCD
H-coil high-frequency deep transcranial magnetic stimulation (dTMS) over the medial prefrontal cortex (mPFC) and anterior cingulate cortex (ACC) has been approved by the Food and Drug Administration for use in treatment-resistant…
- Trial name
- NCT06177470
- Testing
- Accelerated deep iTBS
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Pamukkale University
Obsessive Compulsive Disorder
Neurostimulation and OCD, a MRI Study
This study will focus on the use of repetitive Transcranial Magnetic Stimulation (rTMS) as a treatment of Obsessive Compulsive Disorder (OCD), which is a common illness that impairs quality of life and that can be hard to treat.
- Trial name
- ASLTOC (NCT03918837)
- Testing
- Active rTMS
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospital Center Guillaume Régnier
Obsessive-Compulsive Disorder
Randomized Controlled Trial of Standard ERP and OC-Go
Phase II of this study will examine the efficacy of the OC-Go application via a randomized controlled trial comparing standard exposure and response prevention (ERP) treatment for pediatric obsessive compulsive disorder (OCD) to…
- Trial name
- OC-GoPhaseII (NCT03601312)
- Testing
- Exposure and Response Prevention, OC-Go
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of California, Los Angeles
Major Depressive Disorder, Post Traumatic Stress Disorder
Ketamine Safety and Tolerability in Psychiatric Inpatient Care (KetGD)
This observational registry aims to collect real-world data on ketamine use in psychiatric inpatients within a regional tertiary-reference center.
- Conditions
- Major Depressive Disorder, Post Traumatic Stress Disorder, Obsessive-Compulsive Disorder, Somatoform Disorders
- Trial name
- KetGD (NCT05565352)
- Testing
- Ketamine Hydrochloride
- Where
- Poland
- Volunteers
- 140 people
- Sponsor
- Medical University of Gdansk
Bipolar Affective Disorders, Cyclothymic Disorder
The Influence of the Menstrual Cycle on Lithium and Sertraline Blood Levels
The aim of this study is to determine whether blood levels of lithium or sertraline are affected by different phases of the menstrual cycle and whether there is an effect on psychiatric symptoms.
- Conditions
- Bipolar Affective Disorders, Cyclothymic Disorder, Schizoaffective Disorder, Major Depressive Disorder
- Trial name
- NCT01385709
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Weill Medical College of Cornell University
Anxiety Disorders, Depressive Disorder
Transdiagnostic Treatment Personalization
The primary purpose of this study is to explore whether the efficiency of treatment for anxiety and depressive disorders can be increased using two discrete strategies: personalized skill ordering and 2) treatment discontinuation…
- Conditions
- Anxiety Disorders, Depressive Disorder, Post Traumatic Stress Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT04584879
- Testing
- Standard UP Treatment, Capitalization UP Treatment, Compensation UP Treatment
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shannon E. Sauer-Zavala
Trichotillomania
Awareness Enhancement and Monitoring Device for Treatment of Trichotillomania
The goals of the study are to further design, develop, and test an awareness enhancement and monitoring device, which will be used in the self-awareness training and general treatment of patients with compulsive hair-pulling…
- Trial name
- NCT01654523
- Testing
- Awareness Enhancement and Monitoring Device for Treatment of Trichotillomania
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Michigan
Cognitive Behavioral Therapy, Autism Spectrum Disorder
Internet-Based, Parent-Led Cognitive-Behavioral Therapy for Anxiety in Youth With ASD
This study compares the effectiveness of two levels of therapist support for an internet-based, parent-led cognitive behavioral therapy for youth with anxiety and ASD.
- Conditions
- Cognitive Behavioral Therapy, Autism Spectrum Disorder, Anxiety Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT05284435
- Testing
- Cognitive Behavioral Therapy-Email (iCBT-E), Cognitive Behavioral Therapy-Email and Videoconferencing (iCBT-EV)
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Baylor College of Medicine
Obsessive-Compulsive Disorder, Tricholemmoma
Neural Mechanisms of Response Inhibition Training for OCRD
The impaired ability to suppress an inappropriate but pre-potent response (response inhibition; RI) characterizes several debilitating clinical problems, including obsessive-compulsive and related disorders (OCRD) such as…
- Conditions
- Obsessive-Compulsive Disorder, Tricholemmoma, Skin-Picking
- Trial name
- OCRD (NCT05377125)
- Testing
- Computerized cognitive training
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Wisconsin, Milwaukee
Tourette's Disorder
Omega-3 Fatty Acids in Tourette's Disorder
This study examines the safety and efficacy of omega-3 fatty acids (fish oil) for the treatment of Tourette's Disorder.
- Trial name
- NCT01315327
- Testing
- Omega-3 Fatty Acids, Olive oil
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- NYU Langone Health